The polymorphism -1131T>C in apolipoprotein A5 gene is associated with dyslipidemia in Brazilian subjects

Gene

Volumn 516, Issue 1, 2013, Pages 171-175

  Ferreira, Cláudia N ^a   Carvalho, Maria G ^a   Fernandes, Ana P ^a   Santos, Izabela R ^a   Rodrigues, Kathryna F ^a   Lana, Ângela M Q ^a   Almeida, Cristina R ^b   Loures Vale, Andréia A ^c   Gomes, Karina B ^a   Sousa, Marinez O ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b PETROBRAS   (Brazil)

^c Hospital Geral Socor   (Brazil)

Author keywords

Apolipoprotein; Dyslipidemia; Lipid parameters; Polymorphism

Indexed keywords

APOLIPOPROTEIN A5; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; ALLELE; ARTICLE; BODY MASS; BRAZIL; CARDIOVASCULAR RISK; CASE CONTROL STUDY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DNA POLYMORPHISM; DYSLIPIDEMIA; FEMALE; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MENOPAUSE; PRIORITY JOURNAL; RISK; RISK ASSESSMENT; SEX DIFFERENCE; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; ALLELES; APOLIPOPROTEINS A; BRAZIL; CARDIOVASCULAR DISEASES; CASE-CONTROL STUDIES; CHOLESTEROL; DYSLIPIDEMIAS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; TRIGLYCERIDES;

EID: 84873085393     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2012.12.016     Document Type: Article

References (43)

1. Aouizerat B.E., et al. Genetic analysis of a polymorphism in the human apo A-V gene: effect on plasma lipids. J. Lipid Res. 2003, 44:1167-1173.
2. Araújo F., et al. Lipidic profile of individuals without cardiopathy with overweight and obesity. Arq. Bras. Cardiol. 2005, 84:405-409.
3. Brito D.D., et al. Apolipoprotetein A5-1131T>C polymorphism, but not APOE genotypes, increases susceptibility for dyslipidemia in children and adolescents. Mol. Biol. Rep. 2011, 38:4381-4388.
4. Charriere S., et al. Association of APOA5-1131T>C and S19W gene polymorphisms with both mild hypertriglyceridemia and hyperchylomicronemia in type 2 diabetic patients. Clin. Chim. Acta 2008, 394:99-103.
5. Choy P.C., et al. Lipids and atherosclerosis. Biochem. Cell Biol. 2004, 82:212-224.
6. Endo K., et al. Association found between the promoter region polymorphism in the apolipoprotein A-V gene and the serum triglyceride level in Japanese schoolchildren. Hum. Genet. 2002, 111:570-572.
7. Evans D., Buchwald A., Beil F.U. The single nucleotide polymorphism -1131T>C in the apolipoprotein A5 (APOA5) gene is associated with elevated triglycerides in patients with hyperlipidemia. J. Mol. Med. (Berl.) 2003, 81:645-654.
8. Friedewald W.T., Levy R.I., Fredrickison D.S. Estimation of the concentration of low density lipoprotein cholesterol in plasma, without the use of preparative ultra. Clin. Chem. 1972, 18:499-502.
9. Guardiola M., et al. The apolipoprotein A5 (APOA5) gene predisposes Caucasian children to elevated triglycerides and vitamin E (Four Provinces Study). Atherosclerosis 2010, 212:543-547.
10. Hořínek A., et al. T1131C polymorphism within the apolipoprotein AV gene in hypertriglyceridemic individuals. Atherosclerosis 2003, 167:369-370.
11. Huang X., et al. Association of plasma apolipoprotein AV with lipid profiles in patients with acute coronary syndrome. Atherosclerosis 2009, 204:e99-e102.
12. Jang Y., et al. The apolipoprotein A5-1131T>C promoter polymorphism in Koreans: association with plasma APOA5 and serum triglyceride concentrations, LDL particle size and coronary artery disease. Clin. Chim. Acta 2009, 402:83-87.
13. Jardim P.C., et al. High blood pressure and some risk factors in a Brazilian capital. Arq. Bras. Cardiol. 2007, 88:452-457.
14. Kluger M., Heeren J., Merkel M. Apoprotein A-V: an important regulator of triglyceride metabolism. J. Inherit. Metab. Dis. 2008, 31:281-288.
15. Komurcu-Bayrak E., et al. Gender-modulated impact of apolipoprotein A5 gene (APOA5) -1131T>C and c.56C>G polymorphisms on lipids, dyslipidemia and metabolic syndrome in Turkish adults. Clin. Chem. Lab. Med. 2008, 46:778-784.
16. Lai C.Q., Parnell L.D., Ordovas J.M. The APOA1/C3/A4/A5 gene cluster, lipid metabolism and cardiovascular disease risk. Curr. Opin. Lipidol. 2005, 16:153-166.
17. Lauer M.S., Fontanarosa P.B. NCEP - National Cholesterol Education Program. Executive Summary of The Third Report of The National Cholesterol Education Program - Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). Updated guidelines for cholesterol management. Jama 2001, 285:2486-2497.
18. Li G.P., et al. Genetic effect of two polymorphisms in the apolipoproteín A5 gene and apolipoproteín C3 gene on serum lipids and lipoproteins levels in a Chinese population. Clin. Genet. 2004, 65:470-476.
19. Li Y.Y., et al. Association of apolipoprotein A5 gene polymorphisms and serum lipid levels. Nutr. Metab. Cardiovasc. Dis. 2011, 21:947-956.
20. Liu H., et al. Association between DNA variants sites in the apolipoprotein A5 gene and coronary heart disease in Chinese. Metabolism 2005, 54:568-572.
21. Maász A., et al. Apolipoprotein A5 gene C56G variant confers risk for the development of large-vessel associated ischemic stroke. J. Neurol. 2008, 255:649-654.
22. Mahley R.W., et al. Low levels of high density lipoproteins in Turks, a population with elevated hepatic lipase. High density lipoprotein characterization and gender-specific effects of apolipoprotein e genotype. J. Lipid Res. 2000, 41:1290-1301.
23. Matsunaga A., et al. Strong linkage disequilibrium and association of -1131T>C and c.553G>T of the apolipoprotein A5 gene with hypertriglyceridemia in a Japanese population. Circ. J. 2007, 71:746-752.
24. Maturana M.A., Irigoyen M.C., Spritzer P.M. Menopause, estrogens, and endothelial dysfunction: current concepts. Clinics (Sao Paulo) 2007, 62:77-86.
25. Nabika T., et al. The genetic effect of the apoprotein AV gene on the serum triglyceride level in Japanese. Atherosclerosis 2002, 165:201-204.
26. Olano-Martin E., et al. Influence of apoA-V gene variants on postprandial triglyceride metabolism: impact of gender. J. Lipid Res. 2008, 49:945-953.
27. Parra F.C., et al. Color and genomic ancestry in Brazilians. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:177-182.
28. Peacock R.E., et al. Variation at the lipoprotein lipase and apolipoprotein AI-CIII gene loci are associated with fasting lipid and lipoprotein traits in a population sample from Iceland: interaction between genotype, gender, and smoking status. Genet. Epidemiol. 1997, 14:265-282.
29. Pennacchio L.A., Rubin E.M. Apolipoprotein A5, a newly identified agent that affects plasma triglyceride levels in humans and mice. Arterioscler. Thromb. Vasc. Biol. 2003, 23:529-534.
30. Pennacchio L.A., et al. An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Science 2001, 294:169-173.
31. Pennacchio L.A., et al. Two independent apolipoprotein A5 haplotypes influence plasma triglyceride levels. Hum. Mol. Genet. 2002, 11:3031-3038.
32. Ribalta J., et al. Newly identified apolipoprotein AV gene predisposes to high plasma triglycerides in familial combined hyperlipidemia. Clin. Chem. 2002, 48:1597-1600.
33. Sarwar N., et al. Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. Lancet 2010, 375:1634-1639.
34. Sousa M.O., et al. Interaction between APOA5-1131T>C and APOE polymorphisms and their association with severe hypertriglyceridemia. Clin. Chim. Acta 2008, 395:68-71.
35. Sposito A.C., et al. IV Brazilian Guideline for dyslipidemia and atherosclerosis prevention: Department of Atherosclerosis of Brazilian Society of Cardiology. Arq. Bras. Cardiol. 2007, 88:2-19.
36. Szalai C., et al. Polymorphism in the promoter region of the apolipoprotein A5 gene is associated with an increased susceptibility for coronary artery disease. Atherosclerosis 2004, 173:109-114.
37. Talayero B.G., Sacks F.M. The role of triglycerides in atherosclerosis. Curr. Cardiol. Rep. 2011, 13(6):544-552.
38. Talmud P.J., et al. Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides. Hum. Mol. Genet. 2002, 11:3039-3046.
39. Van der Vliet H.N., et al. Adenoviral overexpression of apolipoprotein A-V reduces serum levels of triglycerides and cholesterol in mice. Biochem. Biophys. Res. Commun. 2002, 295:1156-1159.
40. Wang J., et al. APOA5 genetic variants are markers for classic hyperlipoproteinemia phenotypes and hypertriglyceridemia. Nat. Clin. Pract. Cardiovasc. Med. 2008, 5:730-737.
41. Yamada Y., et al. Prediction of genetic risk for dyslipidemia. Genomics 2007, 90:551-558.
42. Yin R.X., et al. Interactions of the apolipoprotein a5 gene polymorphisms and alcohol consumption on serum lipid levels. PLoS One 2011, 6:e17954.
43. Zhao T., Zhao J. Association of the apolipoprotein A5 gene -1131 T>C polymorphism with fasting blood lipids: a meta-analysis in 37859 subjects. BMC Med. Genet. 2010, 11:120.