Association of apolipoprotein A5 gene polymorphisms and serum lipid levels

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 21, Issue 12, 2011, Pages 947-956

  Li, Y Y ^a,b   Yin, R X ^a   Lai, C Q ^c   Li, M ^d   Long, X J ^a   Li, K L ^a   Liu, W Y ^a   Zhang, L ^a   Wu, J Z ^a  

^a FIRST AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIVERSITY   (China)

^b Guangxi Minzu Hospital   (China)

^c TUFTS UNIVERSITY   (United States)

^d Worker's Hospital of Guangxi Liuzhou Iron and Steel Group Company   (China)

Author keywords

Apolipoproteins; Gene; Lipids; Polymorphism; Risk factors

Indexed keywords

APOA5 PROTEIN, HUMAN; APOLIPOPROTEIN A; LIPID;

ADOLESCENT; ADULT; AGED; ALLELE; ARTICLE; BLOOD; CHINA; CORONARY ARTERY DISEASE; ETHNOLOGY; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETICS; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTRIGLYCERIDEMIA; LEUKOCYTE; MALE; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALLELES; APOLIPOPROTEINS A; CHINA; CORONARY ARTERY DISEASE; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; HUMANS; HYPERCHOLESTEROLEMIA; HYPERTRIGLYCERIDEMIA; LEUKOCYTES; LINKAGE DISEQUILIBRIUM; LIPIDS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; YOUNG ADULT;

EID: 81055148185     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.numecd.2010.04.004     Document Type: Article

References (30)

1. Shekelle R.B., Shryock A.M., Paul O., Lepper M., Stamler J., Liu S., et al. Diet, serum cholesterol, and death from coronary heart disease. The Western Electric study. N Engl J Med 1981, 304:65-70.
2. Jeppesen J., Hein H.O., Suadicani P., Gyntelberg F. Triglyceride concentration and ischemic heart disease: an eight-year follow-up in the Copenhagen Male Study. Circulation 1998, 97:1029-1036.
3. Achari V., Thakur A.K. Association of major modifiable risk factors among patients with coronary artery disease - a retrospective analysis. J Assoc Physicians India 2004, 52:103-108.
4. Durrington P.N., Hunt L., Ishola M., Kane J., Stephens W.P. Serum apolipoproteins AI and B and lipoproteins in middle aged men with and without previous myocardial infarction. Br Heart J 1986, 56:206-212.
5. Gordon D.J., Probstfield J.L., Garrison R.J., Neaton J.D., Castelli W.P., Knoke J.D., et al. High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies. Circulation 1989, 79:8-15.
6. Wu L.L. Review of risk factors for cardiovascular diseases. Ann Clin Lab Sci 1999, 29:127-133.
7. Pérusse L., Rice T., Després J.P., Bergeron J., Province M.A., Gagnon J., et al. Familial resemblance of plasma lipids, lipoproteins and postheparin lipoprotein and hepatic lipases in the HERITAGE Family Study. Arterioscler Thromb Vasc Biol 1997, 17:3263-3269.
8. Ishihara M., Kujiraoka T., Iwasaki T., Nagano M., Takano M., Ishii J., et al. A sandwich enzyme-linked immunosorbent assay for human plasma apolipoprotein A-V concentration. J Lipid Res 2005, 46:2015-2022.
9. Pennacchio L.A., Olivier M., Hubacek J.A., Cohen J.C., Cox D.R., Fruchart J.C., et al. An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Science 2001, 294:169-173.
10. Endo K., Yanagi H., Araki J., Hirano C., Yamakawa-Kobayashi K., Tomura S. Association found between the promoter region polymorphism in the apolipoprotein A-V gene and the serum triglyceride level in Japanese schoolchildren. Hum Genet 2002, 111:570-572.
11. Van der Vliet H.N., Schaap F.G., Levels J.H., Ottenhoff R., Looije N., Wesseling J.G., et al. Adenovirus overexpression of apolipoprotein A-V reduces serum levels of triglycerides and cholesterol in mice. Biochem Biophys Res Commun 2002, 295:1156-1159.
12. Pennacchio L.A., Olivier M., Hubacek J.A., Krauss R.M., Rubin E.M., Cohen J.C. Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels. Hum Mol Genet 2001, 11:3031-3038.
13. Nabika T., Nasreen S., Kobayashi S., Masuda J. The genetic effect of the apoprotein AV gene on the serum triglyceride level in Japanese. Atherosclerosis 2002, 165:201-204.
14. Lai C.Q., Tai E.S., Tan C.E., Cutter J., Chew S.K., Zhu Y.P., et al. The ApoA5 locus is a strong determinant of plasma triglyceride concentrations across ethnic groups in Singapore. J Lipid Res 2003, 44:2365-2373.
15. Talmud P.J., Hawe E., Martin S., Olivier M., Miller G.J., Rubin E.M., et al. Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides. Hum Mol Genet 2002, 11:3039-3046.
16. Aouizerat B.E., Kulkarni M., Heilbron D., Drown D., Raskin S., Pullinger C.R., et al. Genetic analysis of a polymorphism in the human apoA-V gene: effect on plasma lipids. J Lipid Res 2003, 44:1167-1173.
17. Baum L., Tomlinson B., Thomas G.N. ApoA5-1131T>C polymorphism is associated with triglyceride levels in Chinese men. Clin Genet 2003, 63:377-379.
18. Kao J.T., Wen H.C., Chien K.L., Hsu H.C., Lin S.W. A novel genetic variant in the apolipoprotein A5 gene is associated with hypertriglyceridemia. Hum Mol Genet 2003, 12:2533-2539.
19. Chaaba R., Attia N., Hammami S., Smaoui M., Mahjoub S., Hammami M., et al. Association of SNP3 polymorphism in the apolipoprotein A-V gene with plasma triglyceride level in Tunisian type 2 diabetes. Lipids Health Dis 2005, 4:1.
20. Lai C.Q., Demissie S., Cupples L.A., Zhu Y., Adiconis X., Parnell L.D., et al. Influence of the APOA5 locus on plasma triglyceride, lipoprotein subclasses, and CVD risk in the Framingham Heart Study. J Lipid Res 2004, 45:2096-2105.
21. Liu H., Zhang S., Lin J., Li H., Huang A., Xiao C., et al. Association between DNA variant sites in the apolipoprotein A5 gene and coronary heart disease in Chinese. Metabolism 2005, 54:568-572.
22. Hsu L.A., Ko Y.L., Chang C.J., Hu C.F., Wu S., Teng M.S., et al. Genetic variation of apolipoprotein A5 gene is associated with the risk of coronary artery disease among Chinese in Taiwan. Atherosclerosis 2006, 185:143-149.
23. Tang Y., Sun P., Guo D., Ferro A., Ji Y., Chen Q., et al. A genetic variant c.553G>T in the apolipoprotein A5 gene is associated with an increased risk of coronary artery disease and altered triglyceride levels in a Chinese population. Atherosclerosis 2006, 185:433-437.
24. Lee K.W.J., Ayyobi A.F., Frohlich J.J., Hill J.S. APOA5 gene polymorphism modulates levels of triglyceride, HDL cholesterol and FERHDL but is not a risk factor for coronary artery disease. Atherosclerosis 2004, 176:165-172.
25. Ribalta J., Figuera L., Fernandez-Ballart J., Vilella E., Castro Cabezas M., Masana L., et al. Newly identified apolipoprotein AV gene predisposes to high plasma triglycerides in familial combined hyperlipidemia. Clin Chem 2002, 48:1597-1600.
26. Ruixing Y., Yuming C., Shangling P., Fengping H., Tangwei L., Dezhai Y., et al. Effects of demographic, dietary and other lifestyle factors on the prevalence of hyperlipidemia in Guangxi Hei Yi Zhuang and Han populations. Eur J Cardiovasc Prev Rehabil 2006, 13:977-984.
27. Ruixing Y., Limei Y., Yuming C., Dezhai Y., Weixiong L., Muyan L., et al. Prevalence, awareness, treatment, control and risk factors of hypertension in the Guangxi Hei Yi Zhuang and Han populations. Hypertens Res 2006, 29:423-432.
28. Hubácek J.A., Adámková V., Ceska R., Poledne R., Horínek A., Vráblík M. New variants in the apolipoprotein AV gene in individuals with extreme triglyceride levels. Physiol Res 2004, 53:225-228.
29. Hubacek J.A., Adamkova V., Prusikova M., Snejdrlova M., Hirschfeldova K., Lanska V., et al. Impact of apolipoprotein A5 variants on statin treatment efficacy. Pharmacogenomics 2009, 10:945-950.
30. Humphries S., Talmud P., Monsalve V., McKeigue P. RFLP studies in different ethnic groups. Atherosclerosis 1989, 75:249-250.