-
1
-
-
78249276172
-
Hdac3 is essential for the maintenance of chromatin structure and genome stability
-
Bhaskara S, Knutson SK, Jiang G, Chandrasekharan MB, Wilson AJ, Zheng S, Yenamandra A, Locke K, Yuan J, Bonine-Summers AR, Wells CE, Kaiser JF, Washington MK, Zhao Z, Wagner FF, Sun ZW, Xa F, Holson EB, Khabele D, Hiebert SW (2010) Hdac3 is essential for the maintenance of chromatin structure and genome stability. Cancer Cell 18:436-447.
-
(2010)
Cancer Cell
, vol.18
, pp. 436-447
-
-
Bhaskara, S.1
Knutson, S.K.2
Jiang, G.3
Chandrasekharan, M.B.4
Wilson, A.J.5
Zheng, S.6
Yenamandra, A.7
Locke, K.8
Yuan, J.9
Bonine-Summers, A.R.10
Wells, C.E.11
Kaiser, J.F.12
Washington, M.K.13
Zhao, Z.14
Wagner, F.F.15
Sun, Z.W.16
Xa, F.17
Holson, E.B.18
Khabele, D.19
Hiebert, S.W.20
more..
-
2
-
-
0013900616
-
RNA synthesis and histone acetylation during the course of gene activation in lymphocytes
-
Pogo BG, Allfrey VG, Mirsky AE (1966) RNA synthesis and histone acetylation during the course of gene activation in lymphocytes. Proc Natl Acad Sci USA 55:805.
-
(1966)
Proc Natl Acad Sci USA
, vol.55
, pp. 805
-
-
Pogo, B.G.1
Allfrey, V.G.2
Mirsky, A.E.3
-
4
-
-
84862819579
-
Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease
-
Jia H, Pallos J, Jacques V, Lau A, Tang B, Cooper A, Syed A, Purcell J, Chen Y, Sharma S, Sangrey GR, Darnell SB, Plasterer H, Sadri-Vakili G, Gottesfeld JM, Thompson LM, Rusche JR, Marsh JL, Thomas EA (2012) Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease. Neurobiol Dis 46:351-361.
-
(2012)
Neurobiol Dis
, vol.46
, pp. 351-361
-
-
Jia, H.1
Pallos, J.2
Jacques, V.3
Lau, A.4
Tang, B.5
Cooper, A.6
Syed, A.7
Purcell, J.8
Chen, Y.9
Sharma, S.10
Sangrey, G.R.11
Darnell, S.B.12
Plasterer, H.13
Sadri-Vakili, G.14
Gottesfeld, J.M.15
Thompson, L.M.16
Rusche, J.R.17
Marsh, J.L.18
Thomas, E.A.19
-
5
-
-
84857485218
-
Histone deacetylase complexes promote trinucleotide repeat expansions
-
Debacker K, Frizzell A, Gleeson O, Kirkham-McCarthy L, Mertz T, Lahue RS (2012) Histone deacetylase complexes promote trinucleotide repeat expansions. PLoS Biol 10:e1001257.
-
(2012)
PLoS Biol
, vol.10
-
-
Debacker, K.1
Frizzell, A.2
Gleeson, O.3
Kirkham-Mccarthy, L.4
Mertz, T.5
Lahue, R.S.6
-
6
-
-
58149378600
-
The structure and function of histone deacetylases: The target for anti-cancer therapy
-
Zhang Y, Fang H, Jiao J, Xu W (2008) The structure and function of histone deacetylases: the target for anti-cancer therapy. Curr Med Chem 15:2840-2849.
-
(2008)
Curr Med Chem
, vol.15
, pp. 2840-2849
-
-
Zhang, Y.1
Fang, H.2
Jiao, J.3
Xu, W.4
-
7
-
-
84864203255
-
Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
-
Archin NM, Liberty AL, Kashuba AD, Choudhary SK, Kuruc JD, Crooks AM, Parker DC, Anderson EM, Kearney MF, Strain MC, Richman MD, Hudgens MG, Bosch RJ, Coffin JM, Eron JJ, Hazuda DJ, Margolis DM (2012) Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature 487:482-485.
-
(2012)
Nature
, vol.487
, pp. 482-485
-
-
Archin, N.M.1
Liberty, A.L.2
Kashuba, A.D.3
Choudhary, S.K.4
Kuruc, J.D.5
Crooks, A.M.6
Parker, D.C.7
Anderson, E.M.8
Kearney, M.F.9
Strain, M.C.10
Richman, M.D.11
Hudgens, M.G.12
Bosch, R.J.13
Coffin, J.M.14
Eron, J.J.15
Hazuda, D.J.16
Margolis, D.M.17
-
8
-
-
79959337704
-
Inhibitors of histone deacetylases: Correlation between isoform specificity and reactivation of HIV type 1 (HIV-1) from latently infected cells
-
Huber K, Doyon G, Plaks J, Fyne E, Mellors JW, Sluis- Cremer N (2011) Inhibitors of histone deacetylases: correlation between isoform specificity and reactivation of HIV type 1 (HIV-1) from latently infected cells. J Biol Chem 286:22211-22218.
-
(2011)
J Biol Chem
, vol.286
, pp. 22211-22218
-
-
Huber, K.1
Doyon, G.2
Plaks, J.3
Fyne, E.4
Mellors, J.W.5
Sluis- Cremer, N.6
-
9
-
-
38949148986
-
HDAC3 overexpression and colon cancer cell proliferation and differentiation
-
Spurling CC, Godman CA, Noonan EJ, Rasmussen TP, Rosenberg DW, Giardina C (2008) HDAC3 overexpression and colon cancer cell proliferation and differentiation. Mol Carcinog 47:137-147.
-
(2008)
Mol Carcinog
, vol.47
, pp. 137-147
-
-
Spurling, C.C.1
Godman, C.A.2
Noonan, E.J.3
Rasmussen, T.P.4
Rosenberg, D.W.5
Giardina, C.6
-
10
-
-
0034663815
-
Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3
-
Li J, Wang J, Wang J, Nawaz Z, Liu JM, Qin J, Wong J (2000) Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3. EMBO J 19:4342-4350.
-
(2000)
EMBO J
, vol.19
, pp. 4342-4350
-
-
Li, J.1
Wang, J.2
Wang, J.3
Nawaz, Z.4
Liu, J.M.5
Qin, J.6
Wong, J.7
-
11
-
-
79551626803
-
Structural basis for the assembly of the SMRT/ NCoR core transcriptional repression machinery
-
Oberoi J, Fairall L, Watson PJ, Yang J-C, Czimmerer Z, Kampmann T, Goult BT, Greenwood JA, Gooch JT, Kallenberger BC, Nagy L, Neuhaus D, Schwabe JWR (2011) Structural basis for the assembly of the SMRT/ NCoR core transcriptional repression machinery. Nat Struct Mol Biol 18:177-184.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 177-184
-
-
Oberoi, J.1
Fairall, L.2
Watson, P.J.3
Yang, J.-C.4
Czimmerer, Z.5
Kampmann, T.6
Goult, B.T.7
Greenwood, J.A.8
Gooch, J.T.9
Kallenberger, B.C.10
Nagy, L.11
Neuhaus, D.12
Jwr, S.13
-
12
-
-
84855984763
-
Structure of HDAC3 bound to corepressor and inositol tetraphosphate
-
Watson PJ, Fairall L, Santos GM, Schwabe JWR (2012) Structure of HDAC3 bound to corepressor and inositol tetraphosphate. Nature 481:335-340.
-
(2012)
Nature
, vol.481
, pp. 335-340
-
-
Watson, P.J.1
Fairall, L.2
Santos, G.M.3
Schwabe, J.W.R.4
-
13
-
-
0034691131
-
The histone deacetylase-3 complex contains nuclear receptor corepressors
-
Wen Y-D, Perissi V, Staszewski LM, Yang W-M, Krones A, Glass CK, Rosenfeld MG, Seto E (2000) The histone deacetylase-3 complex contains nuclear receptor corepressors. Proc Natl Acad Sci USA 97:7202-7207.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 7202-7207
-
-
Wen, Y.-D.1
Perissi, V.2
Staszewski, L.M.3
Yang, W.-M.4
Krones, A.5
Glass, C.K.6
Rosenfeld, M.G.7
Seto, E.8
-
14
-
-
0036211850
-
The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2
-
Zhang J, Kalkum M, Chait BT, Roeder RG (2002) The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2. Mol Cell 9:611-623.
-
(2002)
Mol Cell
, vol.9
, pp. 611-623
-
-
Zhang, J.1
Kalkum, M.2
Chait, B.T.3
Roeder, R.G.4
-
15
-
-
0035724413
-
The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3
-
Guenther MG, Barak O, Lazar MA (2001) The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3. Mol Cell Biol 21:6091-6101.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 6091-6101
-
-
Guenther, M.G.1
Barak, O.2
Lazar, M.A.3
-
16
-
-
17844371338
-
Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors
-
Codina A, Love JD, Li Y, Lazar MA, Neuhaus D, Schwabe JWR (2005) Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors. Proc Natl Acad Sci USA 102:6009-6014.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 6009-6014
-
-
Codina, A.1
Love, J.D.2
Li, Y.3
Lazar, M.A.4
Neuhaus, D.5
Schwabe, J.W.R.6
-
17
-
-
36649006642
-
Clustering molecular dynamics trajectories: 1. characterizing the performance of different clustering algorithms
-
Shao J, Tanner SW, Thompson N, Cheatham TE (2007) Clustering molecular dynamics trajectories: 1. characterizing the performance of different clustering algorithms. J Chem Theory Comput 3:2312-2334.
-
(2007)
J Chem Theory Comput
, vol.3
, pp. 2312-2334
-
-
Shao, J.1
Tanner, S.W.2
Thompson, N.3
Cheatham, T.E.4
-
18
-
-
58149144730
-
Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors
-
Dowling DP, Gantt SL, Gattis SG, Fierke CA, Christianson DW (2008) Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry 47: 13554-13563.
-
(2008)
Biochemistry
, vol.47
, pp. 13554-13563
-
-
Dowling, D.P.1
Gantt, S.L.2
Gattis, S.G.3
Fierke, C.A.4
Christianson, D.W.5
-
19
-
-
77955808765
-
A proton- shuttle reaction mechanism for histone deacetylase 8 and the CATALYTIC ROLE of METAL IONS
-
Wu R, Wang S, Zhou N, Cao Z, Zhang Y (2010) A proton- shuttle reaction mechanism for histone deacetylase 8 and the CATALYTIC ROLE OF METAL IONS. J Am Chem Soc 132:9471-9479.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 9471-9479
-
-
Wu, R.1
Wang, S.2
Zhou, N.3
Cao, Z.4
Zhang, Y.5
-
20
-
-
35548947488
-
Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8- substrate complex
-
Vannini A, Volpari C, Gallinari P, Jones P, Mattu M, Carfí A, De Francesco R, Steinkuhler C, Di Marco S (2007) Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8- substrate complex. EMBO Rep 8:879-884.
-
(2007)
EMBO Rep
, vol.8
, pp. 879-884
-
-
Vannini, A.1
Volpari, C.2
Gallinari, P.3
Jones, P.4
Mattu, M.5
Carfí, A.6
De Francesco, R.7
Steinkuhler, C.8
Di Marco, S.9
-
21
-
-
84907007074
-
Gaussian 03
-
Frisch MJ, Trucks GW, Schlegel HB, Scuseria GE, Robb MA, Cheeseman JR, Montgomery, Jr. JA, Vreven T, Kudin KN, Burant JC, Millam JM, Iyengar SS, Tomasi J, Barone V, Mennucci B, Cossi M, Scalmani G, Rega N, Petersson GA, Nakatsuji H, Hada M, Ehara M, Toyota K, Fukuda R, Hasegawa J, Ishida M, Nakajima T, Honda Y, Kitao O, Nakai H, Klene M, Li X, Knox JE, Hratchian HP, Cross JB, Bakken V, Adamo C, Jaramillo J, Gomperts R, Stratmann RE, Yazyev O, Austin AJ, Cammi R, Pomelli C, Ochterski JW, Ayala PY, Morokuma K, Voth GA, Salvador P, Dannenberg JJ, Zakrzewski VG, Dapprich S, Daniels AD, Strain MC, Farkas O, Malick DK, Rabuck AD, Raghavachari K, Foresman JB, Ortiz JV, Cui Q, Baboul AG, Clifford S, Cioslowski J, Stefanov BB, Liu G, Liashenko A, Piskorz P, Komaromi I, Martin RL, Fox DJ, Keith T, Al- Laham MA, Peng CY, Nanayakkara A, Challacombe M, Gill PMW, Johnson B, Chen W, Wong MW, Gonzalez C, Pople JA. Gaussian 03, Revision C.02.
-
Revision C.02
-
-
Frisch, M.J.1
Trucks, G.W.2
Schlegel, H.B.3
Scuseria, G.E.4
Robb, M.A.5
Cheeseman, J.R.6
Montgomery Jr., J.A.7
Vreven, T.8
Kudin, K.N.9
Burant, J.C.10
Millam, J.M.11
Iyengar, S.S.12
Tomasi, J.13
Barone, V.14
Mennucci, B.15
Cossi, M.16
Scalmani, G.17
Rega, N.18
Petersson, G.A.19
Nakatsuji, H.20
Hada, M.21
Ehara, M.22
Toyota, K.23
Fukuda, R.24
Hasegawa, J.25
Ishida, M.26
Nakajima, T.27
Honda, Y.28
Kitao, O.29
Nakai, H.30
Klene, M.31
Li, X.32
Knox, J.E.33
Hratchian, H.P.34
Cross, J.B.35
Bakken, V.36
Adamo, C.37
Jaramillo, J.38
Gomperts, R.39
Stratmann, R.E.40
Yazyev, O.41
Austin, A.J.42
Cammi, R.43
Pomelli, C.44
Ochterski, J.W.45
Ayala, P.Y.46
Morokuma, K.47
Voth, G.A.48
Salvador, P.49
Dannenberg, J.J.50
Zakrzewski, V.G.51
Dapprich, S.52
Daniels, A.D.53
Strain, M.C.54
Farkas, O.55
Malick, D.K.56
Rabuck, A.D.57
Raghavachari, K.58
Foresman, J.B.59
Ortiz, J.V.60
Cui, Q.61
Baboul, A.G.62
Clifford, S.63
Cioslowski, J.64
Stefanov, B.B.65
Liu, G.66
Liashenko, A.67
Piskorz, P.68
Komaromi, I.69
Martin, R.L.70
Fox, D.J.71
Keith, T.72
Al- Laham, M.A.73
Peng, C.Y.74
Nanayakkara, A.75
Challacombe, M.76
Pmw, G.77
Johnson, B.78
Chen, W.79
Wong, M.W.80
Gonzalez, C.81
Pople, J.A.82
more..
-
22
-
-
30344440627
-
-
University of California, San Francisco
-
Case DA, Darden TA, Cheatham TE, III, Simmerling CL, Wang J, Duke RE, Luo R, Walker RC, Zhang W, Merz KM, Roberts BP, Wang B, Hayik S, Roitberg A, Seabra G, Kolossvai I, Wong KF, Paesani F, Vanicek J, Liu J, Wu X, Brozell SR, Steinbrecher T, Gohlke H, Cai Q, Ye X, Wang J, Hsieh MJ, Cui G, Roe DR, Mathews DH, Seetin MG, Sagui C, Babin V, Luchko T, Gusarov S, Kovalenko A, Kollman PA (2010) Amber 11. University of California, San Francisco.
-
(2010)
Amber
, vol.11
-
-
Case, D.A.1
Darden, T.A.2
Cheatham, T.E.3
Iii Simmerling, C.L.4
Wang, J.5
Duke, R.E.6
Luo, R.7
Walker, R.C.8
Zhang, W.9
Merz, K.M.10
Roberts, B.P.11
Wang, B.12
Hayik, S.13
Roitberg, A.14
Seabra, G.15
Kolossvai, I.16
Wong, K.F.17
Paesani, F.18
Vanicek, J.19
Liu, J.20
Wu, X.21
Brozell, S.R.22
Steinbrecher, T.23
Gohlke, H.24
Cai, Q.25
Ye, X.26
Wang, J.27
Hsieh, M.J.28
Cui, G.29
Roe, D.R.30
Mathews, D.H.31
Seetin, M.G.32
Sagui, C.33
Babin, V.34
Luchko, T.35
Gusarov, S.36
Kovalenko, A.37
Kollman, P.A.38
more..
-
23
-
-
77956608400
-
Structural survey of zinc containing proteins and the development of the zinc AMBER force field (ZAFF)
-
Peters MB, Yang Y, Wang B, Fusti-Molnár L, Weaver MN, Merz KM (2010) Structural survey of zinc containing proteins and the development of the zinc AMBER force field (ZAFF). J Chem Theory Comput 6: 2935-2947.
-
(2010)
J Chem Theory Comput
, vol.6
, pp. 2935-2947
-
-
Peters, M.B.1
Yang, Y.2
Wang, B.3
Fusti-Molnár, L.4
Weaver, M.N.5
Merz, K.M.6
-
24
-
-
28644432877
-
Very fast empirical prediction and rationalization of protein pKa values
-
Li H, Robertson AD, Jensen JH (2005) Very fast empirical prediction and rationalization of protein pKa values. Proteins 61:704-721.
-
(2005)
Proteins
, vol.61
, pp. 704-721
-
-
Li, H.1
Robertson, A.D.2
Jensen, J.H.3
-
25
-
-
77953513118
-
Improved sidechain torsion potentials for the Amber ff99SB protein force field
-
Lindorff-Larsen K, Piana S, Palmo K, Maragakis P, Klepeis JL, Dror RO, Shaw DE (2010) Improved sidechain torsion potentials for the Amber ff99SB protein force field. Proteins 78:1950-1958.
-
(2010)
Proteins
, vol.78
, pp. 1950-1958
-
-
Lindorff-Larsen, K.1
Piana, S.2
Palmo, K.3
Maragakis, P.4
Klepeis, J.L.5
Dror, R.O.6
Shaw, D.E.7
-
26
-
-
49449085241
-
Determination of alkali and halide monovalent ion parameters for use in explicitly solvated biomolecular simulations
-
Joung IS, Cheatham, TE (2008) Determination of alkali and halide monovalent ion parameters for use in explicitly solvated biomolecular simulations. J Phys Chem B 112:9020-9041.
-
(2008)
J Phys Chem B
, vol.112
, pp. 9020-9041
-
-
Joung, I.S.1
Cheatham, T.E.2
-
27
-
-
33646940952
-
Numerical integration of the cartesian equations of motion of a system with constraints: Molecular dynamics of n-alkanes
-
Ryckaert JP, Ciccotti G, Berendsen HJC (1977) Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes. J Comp Phys 23:327-341.
-
(1977)
J Comp Phys
, vol.23
, pp. 327-341
-
-
Ryckaert, J.P.1
Ciccotti, G.2
Hjc, B.3
|