Montmorillonite K-10 catalyzed green synthesis of 2,6-unsubstituted dihydropyridines as potential inhibitors of PDE4

European Journal of Medicinal Chemistry

Volumn 62, Issue , 2013, Pages 395-404

  Reddy, T Ram ^a,b   Reddy, G Rajeshwar ^a   Reddy, L Srinivasula ^a   Meda, Chandana Lakshmi T ^c   Parsa, Kishore V L ^c   Kumar, K Shiva ^c   Lingappa, Y ^b   Pal, Manojit ^c  

^a DR REDDY'S LABORATORIES LTD   (India)

^b SRI VENKATESWARA UNIVERSITY   (India)

^c INSTITUTE OF LIFE SCIENCES   (India)

Author keywords

Dihydropyridine; MCR; Montmorillonite K 10; PDE4

Indexed keywords

1,4 DIHYDROPYRIDINE DERIVATIVE; DIETHYL 1 (2 METHOXYPHENYL) 4 (4 METHOXYPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 1 (2 METHOXYPHENYL) 4 PHENYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 1 (3 CHLOROPHENYL) 4 (4 FLUOROPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 1 (4 METHOXYPHENYL) 4 PHENYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 4 (3 BROMOPHENYL) 1 (2 METHOXYPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 4 (3 BROMOPHENYL) 1 (4 METHOXYPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 4 (3 CHLOROPHENYL) 1 (2 METHOXYPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXLATE; DIETHYL 4 (3,4 DIFLUOROPHENYL) 1 (2 METHOXYPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 4 (3,4 DIFLUOROPHENYL) 1 (2,4 DIMETHOXYPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 4 (3,4 DIFLUOROPHENYL) 1 (4 METHOXYPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 4 (4 BROMOPHENYL) 1 (2 METHOXYPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 4 (4 BROMOPHENYL) 1 (4 METHOXYPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 4 (4 FLUOROPHENYL) 1 (2 METHOXYPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; DIETHYL 4 (4 FLUOROPHENYL) 1 (4 METHOXYPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; MONTMORILLONITE; MONTMORILLONITE K 10; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV B; TRIETHYL 1 (2 METHOXYPHENYL) 1,4 DIHYDROPYRIDINE 3,4,5 TRICARBOXYLATE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYMATIC ASSAY; ENZYME INHIBITION; ENZYME PURIFICATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR DOCKING;

BENTONITE; CATALYSIS; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; DIHYDROPYRIDINES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PHOSPHODIESTERASE 4 INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84873046050     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.12.052     Document Type: Article

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