Angioedema after tPA: What neurointensivists should know

Neurocritical Care

Volumn 16, Issue 3, 2012, Pages 440-443

  Fugate, Jennifer E ^a   Kalimullah, Ejaaz A ^a   Wijdicks, Eelco F M ^a  

^a MAYO CLINIC   (United States)

Author keywords

Airway management; Angiotensin converting enzyme inhibitors; Keywords angioedema; Thrombolytic therapy; Tissue plasminogen activator; TPA

Indexed keywords

ADRENALIN; ALTEPLASE; ATENOLOL; COMPLEMENT COMPONENT C1S INHIBITOR; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; DEXAMETHASONE; DIPHENHYDRAMINE; HYDROCHLOROTHIAZIDE; LISINOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FIBRINOLYTIC AGENT; TISSUE PLASMINOGEN ACTIVATOR;

AGED; ANGIONEUROTIC EDEMA; ARTICLE; BRAIN ISCHEMIA; CASE REPORT; CEREBRAL ARTERY DISEASE; COMPUTER ASSISTED TOMOGRAPHY; DIFFUSION WEIGHTED IMAGING; FEMALE; HEMIANOPIA; HEMIPLEGIA; HUMAN; HYPERTENSION; LIP DISEASE; LOWER LIPS EDEMA; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; PRIORITY JOURNAL; TONGUE EDEMA; URTICARIA; CEREBROVASCULAR ACCIDENT; CHEMICALLY INDUCED DISORDER; DRUG INTERACTION; INTENSIVE CARE; LIP; METHODOLOGY; TONGUE;

AGED; ANGIOEDEMA; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; DRUG INTERACTIONS; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; INTENSIVE CARE; LIP; STROKE; TISSUE PLASMINOGEN ACTIVATOR; TONGUE;

EID: 84873042266     PISSN: 15416933     EISSN: 15560961     Source Type: Journal    
DOI: 10.1007/s12028-012-9678-0     Document Type: Article

References (20)

1. The National Institute of Neurological Disorders and Stroke rt- PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995;333:1581-7.
2. Wahlgren N, Ahmed N, Davalos A, et al. Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study. Lancet. 2007;369:275-82.
3. Hacke W, Kaste M, Fieschi C, et al. Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Second European-Australasian Acute Stroke Study Investigators. Lancet. 1998;352:1245-51.
4. Hill MD, Buchan AM. Thrombolysis for acute ischemic stroke: results of the Canadian Alteplase for Stroke Effectiveness Study. CMAJ. 2005;172:1307-12.
5. Hill MD, Lye T, Moss H, et al. Hemi-orolingual angioedema and ACE inhibition after alteplase treatment of stroke. Neurology. 2003;60:1525-7.
6. Engelter ST, Fluri F, Buitrago-Tellez C, et al. Life-threatening orolingual angioedema during thrombolysis in acute ischemic stroke. J Neurol. 2005;252:1167-70.
7. Papamitsakis NI, Kuyl J, Lutsep HL, Clark WM. Benign angioedema after thrombolysis for acute stroke. J Stroke Cerebrovasc Dis. 2000;9:79-81.
8. Shaps HJ, Snyder GE, Sama AE, Rudolph GS. Airway compromise secondary to lingual hematoma complicating administration of tissue plasminogen activator for acute ischemic stroke. Ann Emerg Med. 2001;38:447-9.
9. Pancioli A, Brott T, Donaldson V, Miller R. Asymmetric angioneurotic edema associated with thrombolysis for acute stroke. Ann Emerg Med. 1997;30:227-9.
10. Molinaro G, Gervais N, Adam A. Biochemical basis of angioedema associated with recombinant tissue plasminogen activator treatment: an in vitro experimental approach. Stroke. 2002;33:1712-6.
11. Hill MD, Barber PA, Takahashi J, Demchuk AM, Feasby TE, Buchan AM. Anaphylactoid reactions and angioedema during alteplase treatment of acute ischemic stroke. CMAJ. 2000;162:1281-4.
12. Grant NN, Deeb ZE, Chia SH. Clinical experience with angio-tensin- converting enzyme inhibitor-induced angioedema. Otolaryngol Head Neck Surg. 2007;137:931-5.
13. Al-Khudari S, Loochtan MJ, Peterson E, Yaremchuk KL. Management of angiotensin-converting enzyme inhibitor-induced angioedema. Laryngoscope. 2011;121:2327-34.
14. Abdelmalak B, Makary L, Hoban J, Doyle DJ. Dexmedetomidine as sole sedative for awake intubation in management of the critical airway. J Clin Anesth. 2007;19:370-3.
15. Puchner W, Egger P, Puhringer F, Lockinger A, Obwegeser J, Gombotz H. Evaluation of remifentanil as single drug for awake fiberoptic intubation. Acta Anaesthesiol Scand. 2002;46:350-4.
16. Schaeuble J, Heidegger T, Gerig HJ, Ulrilch B, TW S Comparison of etomidate and propofol for fibreoptic intubation as part of an airway management algorithm:a prospective, randomizes, double-blind study. Eur J Anaesthesiol. 2005;22:762-7.
17. Kim YC, Lee SH, Noh GJ, et al. Thermosoftening treatment of the nasotracheal tube before intubation can reduce epistaxis and nasal damage. Anesth Analg. 2000;91:698-701.
18. Maertins M, Wold R, Swider M. Angioedema after administration of tPA for ischemic stroke: case report. Air Med J. 2011;30:276-8.
19. Walls RM, Pollack CV Jr. Successful cricothyrotomy after thrombolytic therapy for acute myocardial infarction: a report of two cases. Ann Emerg Med. 2000;35:188-91.
20. Bas M, Greve J, Stelter K, et al. Therapeutic efficacy of icatibant in angioedema induced by angiotensin-converting enzyme inhibitors: a case series. Ann Emerg Med. 2010;56:278-82.