Dexmedetomidine as sole sedative for awake intubation in management of the critical airway

Journal of Clinical Anesthesia

Volumn 19, Issue 5, 2007, Pages 370-373

  Abdelmalak, Basem ^a   Makary, Laila ^a   Hoban, Jeremy ^a   Doyle, D John ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Awake intubation; Dexmedetomidine; Difficult airway; Fiberoptic bronchoscopy; Sedation

Indexed keywords

ANESTHETIC AGENT; ANTINEOPLASTIC AGENT; DEXMEDETOMIDINE; LIDOCAINE;

ADULT; AGED; AIRWAY OBSTRUCTION; AMNESIA; ANALGESIA; ANAMNESIS; ARTICLE; CASE REPORT; CLINICAL FEATURE; DOSE RESPONSE; DRUG MECHANISM; FEMALE; HUMAN; INTUBATION; LARYNGECTOMY; LARYNGOSCOPY; LOADING DRUG DOSE; MALE; OBESITY; PNEUMONIA; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; SEDATION; SQUAMOUS CELL CARCINOMA; STRIDOR; THORAX RADIOGRAPHY; THYROID MASS; TRACHEA COMPRESSION; TRANQUILIZING ACTIVITY; WAKEFULNESS;

ADULT; AGED; AIRWAY OBSTRUCTION; CONSCIOUS SEDATION; DEXMEDETOMIDINE; FEMALE; FIBER OPTICS; HUMANS; HYPNOTICS AND SEDATIVES; INTUBATION, INTRATRACHEAL; MALE; MIDDLE AGED; WAKEFULNESS;

EID: 34548498412     PISSN: 09528180     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jclinane.2006.09.006     Document Type: Article

References (8)

1. Caplan R.A., Posner K.L., Ward R.J., and Cheney F.W. Adverse respiratory events in anesthesia: a closed claims analysis. Anesthesiology 72 (1990) 828-833
2. Ramsay M.A., Savage T.M., Simpson B.R., and Goodwin R. Controlled sedation with alphaxalone-alphadolone. BMJ 2 (1974) 656-659
3. Maze M. Pharmacology and use of alpha-2 agonists in anaesthesia. Eur Soc Anaesthesiologists Refresh Course RC1 (2003) 37-43
4. Hall J.E., Uhrich T.D., Barney J.A., Arain S.R., and Ebert T.J. Sedative, amnestic, and analgesic properties of small-dose dexmedetomidine infusions. Anesth Analg 90 (2000) 699-705
5. Scher C.S., and Gitlin M.C. Dexmedetomidine and low-dose ketamine provide adequate sedation for awake fiberoptic intubation. Can J Anaesth 50 (2003) 607-610
6. Belleville J.P., Ward D.S., Bloor B.C., and Maze M. Effects of intravenous dexmedetomidine in humans. I. Sedation, ventilation, and metabolic rate. Anesthesiology 77 (1992) 1125-1133
7. Ramsay M.A., and Luterman D.L. Dexmedetomidine as a total intravenous anesthetic agent. Anesthesiology 101 (2004) 787-790
8. Ebert T.J., Hall J.E., Barney J.A., Uhrich T.D., and Colinco M.D. The effects of increasing plasma concentrations of dexmedetomidine in humans. Anesthesiology 93 (2000) 382-394