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Volumn 13, Issue 1, 2013, Pages

In vivo activity of Nisin A and Nisin v against Listeria monocytogenes in mice

Author keywords

Antimicrobial; Bacteriocin; Lantibiotic; Mutagenesis; Nisin; Peptide engineering

Indexed keywords

NISIN A; NISIN V; PHOSPHATE BUFFERED SALINE; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

EID: 84873028768     PISSN: None     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/1471-2180-13-23     Document Type: Article
Times cited : (61)

References (46)
  • 1
    • 0000185593 scopus 로고
    • Limiting factors in the lactic fermentation
    • 16559334
    • Limiting factors in the lactic fermentation. Rogers LA, Whittier EO, J Bacteriol 1928 16 211 229 16559334
    • (1928) J Bacteriol , vol.16 , pp. 211-229
    • Rogers, L.A.1    Whittier, E.O.2
  • 3
    • 0000609108 scopus 로고
    • Nisin and its uses as a food preservative
    • Nisin and its uses as a food preservative. Delves-Broughton J, Food Technol 1990 44 100 117
    • (1990) Food Technol , vol.44 , pp. 100-117
    • Delves-Broughton, J.1
  • 4
    • 20444503846 scopus 로고    scopus 로고
    • Microbial solutions to microbial problems; Lactococcal bacteriocins for the control of undesirable biota in food
    • 10.1111/j.1365-2672.2005.02552.x 15916645
    • Microbial solutions to microbial problems; lactococcal bacteriocins for the control of undesirable biota in food. Guinane CM, Cotter PD, Hill C, Ross RP, J Appl Microbiol 2005 98 1316 1325 10.1111/j.1365-2672.2005.02552.x 15916645
    • (2005) J Appl Microbiol , vol.98 , pp. 1316-1325
    • Guinane, C.M.1    Cotter, P.D.2    Hill, C.3    Ross, R.P.4
  • 5
    • 0029028865 scopus 로고
    • Maturation pathway of nisin and other lantibiotics: Post-translationally modified antimicrobial peptides exported by Gram-positive bacteria
    • 10.1111/j.1365-2958.1995.mmi-17030427.x 8559062
    • Maturation pathway of nisin and other lantibiotics: post-translationally modified antimicrobial peptides exported by Gram-positive bacteria. de Vos WM, Kuipers OP, van der Meer JR, Siezen RJ, Mol Microbiol 1995 17 427 437 10.1111/j.1365-2958.1995.mmi-17030427.x 8559062
    • (1995) Mol Microbiol , vol.17 , pp. 427-437
    • De Vos, W.M.1    Kuipers, O.P.2    Van Der Meer, J.R.3    Siezen, R.J.4
  • 6
    • 0029055380 scopus 로고
    • Biosynthesis and biological activities of lantibiotics with unique post-translational modifications
    • 10.1111/j.1432-1033.1995.tb20627.x 7601145
    • Biosynthesis and biological activities of lantibiotics with unique post-translational modifications. Sahl H, Jack R, Bierbaum G, Eur J Biochem 1995 230 827 853 10.1111/j.1432-1033.1995.tb20627.x 7601145
    • (1995) Eur J Biochem , vol.230 , pp. 827-853
    • Sahl, H.1    Jack, R.2    Bierbaum, G.3
  • 7
    • 65949089371 scopus 로고    scopus 로고
    • Lantibiotics: Mode of action, biosynthesis and bioengineering
    • 10.2174/138920109787048616 19149587
    • Lantibiotics: mode of action, biosynthesis and bioengineering. Bierbaum G, Sahl HG, Curr Pharm Biotechnol 2009 10 2 18 10.2174/138920109787048616 19149587
    • (2009) Curr Pharm Biotechnol , vol.10 , pp. 2-18
    • Bierbaum, G.1    Sahl, H.G.2
  • 9
    • 0035910508 scopus 로고    scopus 로고
    • Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity
    • 11038353
    • Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity. Wiedemann I, Breukink E, van Kraaij C, Kuipers OP, Bierbaum G, de Kruijff B, Sahl HG, J Biol Chem 2001 276 1772 1779 11038353
    • (2001) J Biol Chem , vol.276 , pp. 1772-1779
    • Wiedemann, I.1    Breukink, E.2    Van Kraaij, C.3    Kuipers, O.P.4    Bierbaum, G.5    De Kruijff, B.6    Sahl, H.G.7
  • 10
    • 2342498649 scopus 로고    scopus 로고
    • Lipid II-mediated pore formation by the peptide antibiotic nisin: A black lipid membrane study
    • 10.1128/JB.186.10.3259-3261.2004 15126490
    • Lipid II-mediated pore formation by the peptide antibiotic nisin: a black lipid membrane study. Wiedemann I, Benz R, Sahl HG, J Bacteriol 2004 186 3259 3261 10.1128/JB.186.10.3259-3261.2004 15126490
    • (2004) J Bacteriol , vol.186 , pp. 3259-3261
    • Wiedemann, I.1    Benz, R.2    Sahl, H.G.3
  • 11
    • 13844314218 scopus 로고    scopus 로고
    • Bacterial lantibiotics: Strategies to improve therapeutic potential
    • 10.2174/1389203053027584 15638769
    • Bacterial lantibiotics: strategies to improve therapeutic potential. Cotter PD, Hill C, Ross RP, Curr Protein Pept Sci 2005 6 61 75 10.2174/1389203053027584 15638769
    • (2005) Curr Protein Pept Sci , vol.6 , pp. 61-75
    • Cotter, P.D.1    Hill, C.2    Ross, R.P.3
  • 12
    • 62149120629 scopus 로고    scopus 로고
    • Discovery of medically significant lantibiotics
    • 10.2174/157016309787581075 19275538
    • Discovery of medically significant lantibiotics. Piper C, Cotter PD, Ross RP, Hill C, Curr Drug Discov Technol 2009 6 1 18 10.2174/157016309787581075 19275538
    • (2009) Curr Drug Discov Technol , vol.6 , pp. 1-18
    • Piper, C.1    Cotter, P.D.2    Ross, R.P.3    Hill, C.4
  • 13
    • 37349086129 scopus 로고    scopus 로고
    • Two-peptide lantibiotics: A medical perspective
    • 10.2174/138955707782795638 18220976
    • Two-peptide lantibiotics: a medical perspective. Lawton EM, Ross RP, Hill C, Cotter PD, Mini Rev Med Chem 2007 7 1236 1247 10.2174/138955707782795638 18220976
    • (2007) Mini Rev Med Chem , vol.7 , pp. 1236-1247
    • Lawton, E.M.1    Ross, R.P.2    Hill, C.3    Cotter, P.D.4
  • 14
    • 84875912564 scopus 로고    scopus 로고
    • New antibiotic compound enters phase I clinical trial
    • New antibiotic compound enters phase I clinical trial, http://www.wellcome.ac.uk/News/2011/News/WTVM053339.htm
  • 15
    • 77955814236 scopus 로고    scopus 로고
    • Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes
    • 10.1073/pnas.1008285107 20628010
    • Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes. Foulston LC, Bibb MJ, Proc Natl Acad Sci U S A 2010 107 13461 13466 10.1073/pnas.1008285107 20628010
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 13461-13466
    • Foulston, L.C.1    Bibb, M.J.2
  • 16
    • 79953242162 scopus 로고    scopus 로고
    • Efficacy of the new lantibiotic NAI-107 in experimental infections induced by MDR Gram-positive pathogens
    • 10.1128/AAC.01288-10 21220527
    • Efficacy of the new lantibiotic NAI-107 in experimental infections induced by MDR Gram-positive pathogens. Jabes D, Brunati C, Candiani G, Riva S, Romano G, Donadio S, Antimicrob Agents Chemother 2011 55 1671 1676 10.1128/AAC.01288-10 21220527
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 1671-1676
    • Jabes, D.1    Brunati, C.2    Candiani, G.3    Riva, S.4    Romano, G.5    Donadio, S.6
  • 17
    • 84954358663 scopus 로고    scopus 로고
    • Therapeutic potential of type A (I) lantibiotics, a group of cationic peptide antibiotics
    • 10.1016/j.mib.2008.09.008 18848642
    • Therapeutic potential of type A (I) lantibiotics, a group of cationic peptide antibiotics. Smith L, Hillman J, Curr Opin Microbiol 2008 11 401 408 10.1016/j.mib.2008.09.008 18848642
    • (2008) Curr Opin Microbiol , vol.11 , pp. 401-408
    • Smith, L.1    Hillman, J.2
  • 18
    • 84856479279 scopus 로고    scopus 로고
    • The lantibiotic lacticin 3147 prevents systemic spread of Staphylococcus aureus in a murine infection model
    • 2012.
    • The lantibiotic lacticin 3147 prevents systemic spread of Staphylococcus aureus in a murine infection model. Piper C, Casey PG, Hill C, Cotter PD, Int J Microbiol 2012 2012.
    • (2012) Int J Microbiol
    • Piper, C.1    Casey, P.G.2    Hill, C.3    Cotter, P.D.4
  • 19
    • 0031949637 scopus 로고    scopus 로고
    • Antibacterial efficacy of nisin against multidrug-resistant Gram-positive pathogens
    • 10.1093/jac/41.3.341 9578160
    • Antibacterial efficacy of nisin against multidrug-resistant Gram-positive pathogens. Severina E, Severin A, Tomasz A, J Antimicrob Chemother 1998 41 341 347 10.1093/jac/41.3.341 9578160
    • (1998) J Antimicrob Chemother , vol.41 , pp. 341-347
    • Severina, E.1    Severin, A.2    Tomasz, A.3
  • 20
    • 0036848132 scopus 로고    scopus 로고
    • Nisin, alone and combined with peptidoglycan-modulating antibiotics: Activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci
    • 10.1093/jac/dkf190 12407132
    • Nisin, alone and combined with peptidoglycan-modulating antibiotics: activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci. Brumfitt W, Salton MR, Hamilton-Miller JM, J Antimicrob Chemother 2002 50 731 734 10.1093/jac/dkf190 12407132
    • (2002) J Antimicrob Chemother , vol.50 , pp. 731-734
    • Brumfitt, W.1    Salton, M.R.2    Hamilton-Miller, J.M.3
  • 21
    • 69049102140 scopus 로고    scopus 로고
    • A comparison of the activities of lacticin 3147 and nisin against drug-resistant Staphylococcus aureus and Enterococcus species
    • A comparison of the activities of lacticin 3147 and nisin against drug-resistant Staphylococcus aureus and Enterococcus species. Piper C, Draper LA, Cotter PD, Ross RP, Hill C, J Antimicrob Chemother 2009 63 546 551
    • (2009) J Antimicrob Chemother , vol.63 , pp. 546-551
    • Piper, C.1    Draper, L.A.2    Cotter, P.D.3    Ross, R.P.4    Hill, C.5
  • 22
    • 79955421170 scopus 로고    scopus 로고
    • Bioengineering of a nisin A-producing Lactococcus lactis to create isogenic strains producing the natural variants nisin F, Q and Z
    • 10.1111/j.1751-7915.2010.00207.x 21375711
    • Bioengineering of a nisin A-producing Lactococcus lactis to create isogenic strains producing the natural variants nisin F, Q and Z. Piper C, Hill C, Cotter PD, Ross RP, Microb Biotechnol 2011 4 375 382 10.1111/j.1751-7915. 2010.00207.x 21375711
    • (2011) Microb Biotechnol , vol.4 , pp. 375-382
    • Piper, C.1    Hill, C.2    Cotter, P.D.3    Ross, R.P.4
  • 24
    • 0031821357 scopus 로고    scopus 로고
    • Activity of nisin against Streptococcus pneumoniae, in vitro, and in a mouse infection model
    • 10.1093/jac/42.2.277 9738856
    • Activity of nisin against Streptococcus pneumoniae, in vitro, and in a mouse infection model. Goldstein BP, Wei J, Greenberg K, Novick R, J Antimicrob Chemother 1998 42 277 278 10.1093/jac/42.2.277 9738856
    • (1998) J Antimicrob Chemother , vol.42 , pp. 277-278
    • Goldstein, B.P.1    Wei, J.2    Greenberg, K.3    Novick, R.4
  • 25
    • 0005678537 scopus 로고
    • The treatment of bovine streptococcal and staphylococcal mastitis with nisin
    • The treatment of bovine streptococcal and staphylococcal mastitis with nisin. Taylor J, Hirsch AR, Mattick AT, Vet Res 1949 61 197 198
    • (1949) Vet Res , vol.61 , pp. 197-198
    • Taylor, J.1    Hirsch, A.R.2    Mattick, A.T.3
  • 26
    • 35948966079 scopus 로고    scopus 로고
    • Efficacy of nisin in treatment of clinical mastitis in lactating dairy cows
    • 10.3168/jds.2007-0153 17639009
    • Efficacy of nisin in treatment of clinical mastitis in lactating dairy cows. Cao LT, Wu JQ, Xie F, Hu SH, Mo Y, J Dairy Sci 2007 90 3980 3985 10.3168/jds.2007-0153 17639009
    • (2007) J Dairy Sci , vol.90 , pp. 3980-3985
    • Cao, L.T.1    Wu, J.Q.2    Xie, F.3    Hu, S.H.4    Mo, Y.5
  • 27
    • 35948938492 scopus 로고    scopus 로고
    • Therapeutic effect of nisin Z on subclinical mastitis in lactating cows
    • 10.1128/AAC.00629-07 17606675
    • Therapeutic effect of nisin Z on subclinical mastitis in lactating cows. Wu J, Hu S, Cao L, Antimicrob Agents Chemother 2007 51 3131 3135 10.1128/AAC.00629-07 17606675
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 3131-3135
    • Wu, J.1    Hu, S.2    Cao, L.3
  • 28
    • 58149295989 scopus 로고    scopus 로고
    • Nisin F in the treatment of respiratory tract infections caused by Staphylococcus aureus
    • 10.1111/j.1472-765X.2008.02488.x 19018962
    • Nisin F in the treatment of respiratory tract infections caused by Staphylococcus aureus. De Kwaadsteniet M, Doeschate KT, Dicks LM, Lett Appl Microbiol 2009 48 65 70 10.1111/j.1472-765X.2008.02488.x 19018962
    • (2009) Lett Appl Microbiol , vol.48 , pp. 65-70
    • De Kwaadsteniet, M.1    Doeschate, K.T.2    Dicks, L.M.3
  • 29
    • 78349303438 scopus 로고    scopus 로고
    • The ability of nisin F to control Staphylococcus aureus infection in the peritoneal cavity, as studied in mice
    • 10.1111/j.1472-765X.2010.02948.x 21029139
    • The ability of nisin F to control Staphylococcus aureus infection in the peritoneal cavity, as studied in mice. Brand AM, De Kwaadsteniet M, Dicks LMT, Lett Appl Microbiol 2010 51 645 649 10.1111/j.1472-765X.2010.02948.x 21029139
    • (2010) Lett Appl Microbiol , vol.51 , pp. 645-649
    • Brand, A.M.1    De Kwaadsteniet, M.2    Dicks, L.M.T.3
  • 30
    • 84858287925 scopus 로고    scopus 로고
    • Nisin F-loaded brushite bone cement prevented the growth of Staphylococcus aureus in vivo
    • 10.1111/j.1365-2672.2012.05241.x 22268790
    • Nisin F-loaded brushite bone cement prevented the growth of Staphylococcus aureus in vivo. van Staden AD, Brand AM, Dicks LMT, J Appl Microbiol 2012 112 831 840 10.1111/j.1365-2672.2012.05241.x 22268790
    • (2012) J Appl Microbiol , vol.112 , pp. 831-840
    • Van Staden, A.D.1    Brand, A.M.2    Dicks, L.M.T.3
  • 31
    • 78649556678 scopus 로고    scopus 로고
    • The dawning of a 'Golden era' in lantibiotic bioengineering
    • 10.1111/j.1365-2958.2010.07406.x 21091497
    • The dawning of a 'Golden era' in lantibiotic bioengineering. Field D, Hill C, Cotter PD, Ross RP, Mol Microbiol 2010 78 1077 1087 10.1111/j.1365-2958. 2010.07406.x 21091497
    • (2010) Mol Microbiol , vol.78 , pp. 1077-1087
    • Field, D.1    Hill, C.2    Cotter, P.D.3    Ross, R.P.4
  • 32
    • 45149121558 scopus 로고    scopus 로고
    • The generation of nisin variants with enhanced activity against specific Gram-positive pathogens
    • 10.1111/j.1365-2958.2008.06279.x 18485077
    • The generation of nisin variants with enhanced activity against specific Gram-positive pathogens. Field D, O'Connor PM, Cotter PD, Hill C, Ross RP, Mol Microbiol 2008 69 218 230 10.1111/j.1365-2958.2008.06279.x 18485077
    • (2008) Mol Microbiol , vol.69 , pp. 218-230
    • Field, D.1    O'Connor, P.M.2    Cotter, P.D.3    Hill, C.4    Ross, R.P.5
  • 33
    • 78650097693 scopus 로고    scopus 로고
    • The gene encoded antimicrobial peptides, a template for the design of novel anti-mycobacterial drugs
    • 10.4161/bbug.1.6.13642 21468208
    • The gene encoded antimicrobial peptides, a template for the design of novel anti-mycobacterial drugs. Carroll J, Field D, O' Connor PM, Cotter PD, Coffey A, Hill C, Ross RP, O' Mahony J, Bioengineered Bugs 2010 1 408 412 10.4161/bbug.1.6.13642 21468208
    • (2010) Bioengineered Bugs , vol.1 , pp. 408-412
    • Carroll, J.1    Field, D.2    O'Connor, P.M.3    Cotter, P.D.4    Coffey, A.5    Hill, C.6    Ross, R.P.7    O'Mahony, J.8
  • 34
    • 77954168712 scopus 로고    scopus 로고
    • Studies with bioengineered nisin peptides highlight the broad-spectrum potency of nisin v
    • 10.1111/j.1751-7915.2010.00184.x 21255345
    • Studies with bioengineered nisin peptides highlight the broad-spectrum potency of nisin V. Field D, Quigley L, O'Connor PM, Rea MC, Daly K, Cotter PD, Hill C, Ross RP, Microb Biotechnol 2010 3 473 486 10.1111/j.1751-7915.2010. 00184.x 21255345
    • (2010) Microb Biotechnol , vol.3 , pp. 473-486
    • Field, D.1    Quigley, L.2    O'Connor, P.M.3    Rea, M.C.4    Daly, K.5    Cotter, P.D.6    Hill, C.7    Ross, R.P.8
  • 35
    • 34248190621 scopus 로고    scopus 로고
    • Improved luciferase tagging system for Listeria monocytogenes allows real-time monitoring in vivo and in vitro
    • 10.1128/AEM.02940-06 17351089
    • Improved luciferase tagging system for Listeria monocytogenes allows real-time monitoring in vivo and in vitro. Riedel CU, Monk IR, Casey PG, Morrissey D, O'Sullivan GC, Tangney M, Hill C, Gahan CGM, Appl Environ Microbiol 2007 73 3091 3094 10.1128/AEM.02940-06 17351089
    • (2007) Appl Environ Microbiol , vol.73 , pp. 3091-3094
    • Riedel, C.U.1    Monk, I.R.2    Casey, P.G.3    Morrissey, D.4    O'Sullivan, G.C.5    Tangney, M.6    Hill, C.7    Gahan, C.G.M.8
  • 36
    • 0038647812 scopus 로고    scopus 로고
    • The bacteriocin piscicolin 126 retains antilisterial activity in vivo
    • 10.1093/jac/dkg229 12716771
    • The bacteriocin piscicolin 126 retains antilisterial activity in vivo. Ingham A, Ford M, Moore RJ, Tizard M, J Antimicrob Chemother 2003 51 1365 1371 10.1093/jac/dkg229 12716771
    • (2003) J Antimicrob Chemother , vol.51 , pp. 1365-1371
    • Ingham, A.1    Ford, M.2    Moore, R.J.3    Tizard, M.4
  • 37
    • 67650305939 scopus 로고    scopus 로고
    • In vivo study on the effectiveness of pediocin PA-1 and Pediococcus acidilactici UL5 at inhibiting Listeria monocytogenes
    • 10.1016/j.ijfoodmicro.2009.05.005 19541383
    • In vivo study on the effectiveness of pediocin PA-1 and Pediococcus acidilactici UL5 at inhibiting Listeria monocytogenes. Dabour N, Zihler A, Kheadr E, Lacroix C, Fliss I, Int J Food Microbiol 2009 133 225 233 10.1016/j.ijfoodmicro.2009.05.005 19541383
    • (2009) Int J Food Microbiol , vol.133 , pp. 225-233
    • Dabour, N.1    Zihler, A.2    Kheadr, E.3    Lacroix, C.4    Fliss, I.5
  • 38
    • 33645119895 scopus 로고    scopus 로고
    • Investigation of the cytotoxicity of eukaryotic and prokaryotic antimicrobial peptides in intestinal epithelial cells in vitro
    • 10.1016/j.bcp.2006.01.012 16530733
    • Investigation of the cytotoxicity of eukaryotic and prokaryotic antimicrobial peptides in intestinal epithelial cells in vitro. Maher S, McClean S, Biochem Pharmacol 2006 71 1289 1298 10.1016/j.bcp.2006.01.012 16530733
    • (2006) Biochem Pharmacol , vol.71 , pp. 1289-1298
    • Maher, S.1    McClean, S.2
  • 39
    • 37449032001 scopus 로고    scopus 로고
    • Evaluation of developmental toxicity of microbicide nisin in rats
    • 10.1016/j.fct.2007.09.006 17949878
    • Evaluation of developmental toxicity of microbicide nisin in rats. Gupta SM, Aranha CC, Reddy KV, Food Chem Toxicol 2008 46 598 603 10.1016/j.fct.2007. 09.006 17949878
    • (2008) Food Chem Toxicol , vol.46 , pp. 598-603
    • Gupta, S.M.1    Aranha, C.C.2    Reddy, K.V.3
  • 40
    • 0025330037 scopus 로고
    • Some chemical and physical properties of nisin, a small-protein antibiotic produced by Lactococcus lactis
    • 2119570
    • Some chemical and physical properties of nisin, a small-protein antibiotic produced by Lactococcus lactis. Liu W, Hansen JN, Appl Environ Microbiol 1990 56 2551 2558 2119570
    • (1990) Appl Environ Microbiol , vol.56 , pp. 2551-2558
    • Liu, W.1    Hansen, J.N.2
  • 41
    • 0029093410 scopus 로고
    • Improvement of solubility and stability of the antimicrobial peptide nisin by protein engineering
    • 7487019
    • Improvement of solubility and stability of the antimicrobial peptide nisin by protein engineering. Rollema HS, Kuipers OP, Both P, de Vos WM, Siezen RJ, Appl Environ Microbiol 1995 61 2873 2878 7487019
    • (1995) Appl Environ Microbiol , vol.61 , pp. 2873-2878
    • Rollema, H.S.1    Kuipers, O.P.2    Both, P.3    De Vos, W.M.4    Siezen, R.J.5
  • 42
    • 84862011041 scopus 로고    scopus 로고
    • Bioengineered nisin derivatives with enhanced activity in complex matrices
    • 10.1111/j.1751-7915.2011.00324.x 22260415
    • Bioengineered nisin derivatives with enhanced activity in complex matrices. Rouse S, Field D, Daly KM, O'Connor PM, Cotter PD, Hill C, Ross RP, Microb Biotechnol 2012 5 501 508 10.1111/j.1751-7915.2011.00324.x 22260415
    • (2012) Microb Biotechnol , vol.5 , pp. 501-508
    • Rouse, S.1    Field, D.2    Daly, K.M.3    O'Connor, P.M.4    Cotter, P.D.5    Hill, C.6    Ross, R.P.7
  • 43
    • 3142701459 scopus 로고    scopus 로고
    • Site-directed mutagenesis of the hinge region of nisin Z and properties of nisin Z mutants
    • 10.1007/s00253-004-1599-1 15048591
    • Site-directed mutagenesis of the hinge region of nisin Z and properties of nisin Z mutants. Yuan J, Zhang ZZ, Chen XZ, Yang W, Huan LD, Appl Microbiol Biotechnol 2004 64 806 815 10.1007/s00253-004-1599-1 15048591
    • (2004) Appl Microbiol Biotechnol , vol.64 , pp. 806-815
    • Yuan, J.1    Zhang, Z.Z.2    Chen, X.Z.3    Yang, W.4    Huan, L.D.5
  • 44
    • 84867326984 scopus 로고    scopus 로고
    • Bioengineered nisin A derivatives with enhanced activity against both Gram positive and Gram negative pathogens
    • 10.1371/journal.pone.0046884 23056510
    • Bioengineered nisin A derivatives with enhanced activity against both Gram positive and Gram negative pathogens. Field D, Begley M, O'Connor PM, Daly KM, Hugenholtz F, Cotter PD, Hill C, Ross RP, PLoS One 2012 7 46884 10.1371/journal.pone.0046884 23056510
    • (2012) PLoS One , vol.7 , pp. 546884
    • Field, D.1    Begley, M.2    O'Connor, P.M.3    Daly, K.M.4    Hugenholtz, F.5    Cotter, P.D.6    Hill, C.7    Ross, R.P.8
  • 45
    • 77955096108 scopus 로고    scopus 로고
    • A 90-day oral toxicity study of nisin A, an anti-microbial peptide derived from Lactococcus lactis subsp. lactis, in F344 rats
    • 10.1016/j.fct.2010.06.002 20621644
    • A 90-day oral toxicity study of nisin A, an anti-microbial peptide derived from Lactococcus lactis subsp. lactis, in F344 rats. Hagiwara A, Imai N, Nakashima H, Toda Y, Kawabe M, Furukawa F, Delves-Broughton J, Yasuhara K, Hayashi S-M, Food Chem Toxicol 2010 48 2421 2428 10.1016/j.fct.2010.06.002 20621644
    • (2010) Food Chem Toxicol , vol.48 , pp. 2421-2428
    • Hagiwara, A.1    Imai, N.2    Nakashima, H.3    Toda, Y.4    Kawabe, M.5    Furukawa, F.6    Delves-Broughton, J.7    Yasuhara, K.8    Hayashi, S.-M.9
  • 46
    • 0027162304 scopus 로고
    • Characterization of the nisin gene cluster nisABTCIPR of Lactococcus lactis. Requirement of expression of the nisA and nisI genes for development of immunity
    • 10.1111/j.1432-1033.1993.tb18143.x 7689965
    • Characterization of the nisin gene cluster nisABTCIPR of Lactococcus lactis. Requirement of expression of the nisA and nisI genes for development of immunity. Kuipers OP, Beerthuyzen MM, Siezen RJ, De Vos WM, Eur J Biochem 1993 216 281 291 10.1111/j.1432-1033.1993.tb18143.x 7689965
    • (1993) Eur J Biochem , vol.216 , pp. 281-291
    • Kuipers, O.P.1    Beerthuyzen, M.M.2    Siezen, R.J.3    De Vos, W.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.