Characterization of PVL/ACME-positive methicillin-resistant staphylococcus aureus (Genotypes ST8-MRSA-IV and ST5-MRSA-II) isolated from a university hospital in Japan

Microbial Drug Resistance

Volumn 19, Issue 1, 2013, Pages 48-56

  Kawaguchiya, Mitsuyo ^a   Urushibara, Noriko ^a   Yamamoto, Dai ^a   Yamashita, Toshiharu ^a   Shinagawa, Masaaki ^a   Watanabe, Naoki ^a   Kobayashi, Nobumichi ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; COAGULASE; ERYTHROMYCIN; KANAMYCIN; TETRACYCLINE; VIRULENCE FACTOR;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; APH(3') IIIA; ARGININE CATABOLIC MOBILE ELEMENT; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATION; GENE IDENTIFICATION; GENE SEQUENCE; GENETIC PARAMETERS; GENOTYPE; JAPAN; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MSRA GENE; NONHUMAN; PANTON VALENTINE LEUKOCIDIN GENE; PREVALENCE; PRIORITY JOURNAL; STAPHYLOCOCCAL CASSETTE CHROMOSOME MEC TYPE IVA; TET GENE; UNIVERSITY HOSPITAL;

ANTI-BACTERIAL AGENTS; BACTERIAL TOXINS; BASE SEQUENCE; DNA, BACTERIAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; EXOTOXINS; GENOTYPE; HOSPITALS, UNIVERSITY; HUMANS; JAPAN; LEUKOCIDINS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; SEQUENCE ALIGNMENT; STAPHYLOCOCCAL INFECTIONS; VIRULENCE FACTORS;

IVA; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

EID: 84872964191     PISSN: 10766294     EISSN: 19318448     Source Type: Journal    
DOI: 10.1089/mdr.2012.0089     Document Type: Article

References (37)

1. Aung, M.S., N. Urushibara, M. Kawaguchiya, T.S. Aung, S. Mya, T. San, K.M. Nwe, and N. Kobayashi. 2011. Virulence factors and genetic characteristics of methicillinresistant and -susceptible Staphylococcus aureus isolates in Myanmar. Microb. Drug Resist. 17:525-535
2. Baba, T., F. Takeuchi, M. Kuroda, H. Yuzawa, K. Aoki, A. Oguchi, Y. Nagai, N. Iwama, K. Asano, T. Naimi, H. Kuroda, L. Cui, K. Yamamoto, and K. Hiramatsu. 2002. Genome and virulence determinants of high virulence community-Acquired MRSA. Lancet 359:1819-1827
3. Barbier, F., D. Lebeaux, D. Hernandez, A.S. Delannoy, V. Caro, P. François, J. Schrenzel, E. Ruppé, K. Gaillard, M. Wolff, S. Brisse, A. Andremont, and R. Ruimy. 2011. High prevalence of the arginine catabolic mobile element in carriage isolates of methicillin-resistant Staphylococcus epidermidis. J. Antimicrob. Chemother. 66:29-36
4. Carpaij, N., R.J. Willems, T.W. Rice, R.A. Weinstein, J. Hinds, A.A. Witney, J.A. Lindsay, M.J. Bonten, and A.C. Fluit. 2011. Genetic variation in spatio-Temporal confined USA300 community-Associated MRSA isolates: A shift from clonal dispersion to genetic evolution? PLoS One 6:e16419
5. Clinical and Laboratory Standards Institute. 2009. Performance Standards for Antimicrobial Susceptibility Testing; 19th Informational Supplement. CLSI document M100-S18. Clinical and Laboratory Standards Institute, Wayne, PA.
6. Coombs, G.W., S. Monecke, J.C. Pearson, H.L. Tan, Y.K. Chew, L. Wilson, R. Ehricht, F.G. O'Brien, and K.J. Christiansen. 2011. Evolution and diversity of communityassociated methicillin-resistant Staphylococcus aureus in a geographical region. BMC Microbiol. 11:215
7. Diep, B.A., S.R. Gill, R.F. Chang, T.H. Phan, J.H. Chen, M.G. Davidson, F. Lin, J. Lin, H.A. Carleton, E.F. Mongodin, G.F. Sensabaugh, and F. Perdreau-Remington. 2006. Complete genome sequence of USA300, an epidemic clone of community-Acquired meticillin-resistant Staphylococcus aureus. Lancet 367:731-739
8. Diep, B.A., G.G. Stone, L. Basuino, C.J. Graber, A. Miller, S.A. des Etages, A. Jones, A.M. Palazzolo-Ballance, F. Perdreau-Remington, G.F. Sensabaugh, F.R. DeLeo, and H.F. Chambers. 2008. The arginine catabolic mobile element and staphylococcal chromosomal cassette mec linkage: Convergence of virulence and resistance in the USA300 clone of methicillin-resistant Staphylococcus aureus. J. Infect. Dis. 197:1523-1530
9. Enright, M.C., N.P. Day, C.E. Davies, S.J. Peacock, and B.G. Spratt. 2000. Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus. J. Clin. Microbiol. 38:1008-1015
10. Goering, R.V., L.K. McDougal, G.E. Fosheim, K.K. Bonnstetter, D.J. Wolter, and F.C. Tenover. 2007. Epidemiologic distribution of the arginine catabolic mobile element among selected methicillin-resistant and methicillin-susceptible Staphylococcus aureus isolates. J. Clin. Microbiol. 45:1981-1984
11. Higashiyama, M., T. Ito, X. Han, K. Ono, K. Minamimura, F. Sakakibara, A. Tanno, J. Nishiyama, J. Hatada, K. Hiramatsu, and A. Kawana. 2010. Epidural abscess caused by community-Associated methicillin-resistant Staphylococcus aureus strain USA300 in japan. J. Infect. Chemother. 16: 345-349
12. Highlander, S.K., K.G. Hulte'n, X. Qin, H. Jiang, S. Yerrapragada, E.O. Mason, Jr., Y. Shang, T.M. Williams, R.M. Fortunov, Y. Liu, O. Igboeli, J. Petrosino, M. Tirumalai, A. Uzman, G.E. Fox, A.M. Cardenas, D.M. Muzny, L. Hemphill, Y. Ding, S. Dugan, P.R. Blyth, C.J. Buhay, H.H. Dinh, A.C. Hawes, M. Holder, C.L. Kovar, S.L. Lee, W. Liu, L.V. Nazareth, Q. Wang, J. Zhou, S.L. Kaplan, and G. Weinstock. 2007. Subtle genetic changes enhance virulence of methicillin resistant and sensitive Staphylococcus aureus. BMC Microbiol. 7:99
13. Higuchi, W., S. Mimura, Y. Kurosawa, T. Takano, Y. Iwao, S. Yabe, O. Razvina, A. Nishiyama, Y. Ikeda-Dantsuji, F. Sakai, H. Hanaki, and T. Yamamoto. 2010. Emergence of the community-Acquired methicillin-resistant Staphylococcus aureus USA300 clone in a Japanese child, demonstrating multiple divergent strains in Japan. J. Infect. Chemother. 16:292-297
14. Hirose, M., N. Kobayashi, S. Ghosh, S.K. Paul, T. Shen, N. Urushibara, M. Kawaguchiya, M. Shinagawa, and N. Watanabe. 2010. Identification of staphylocoagulase genotypes I-X and discrimination of type IV and V subtypes by multiplex PCR assay for clinical isolates of Staphylococcus aureus. Jpn. J. Infect. Dis. 63:257-263
15. Kawaguchiya, M., N. Urushibara, O. Kuwahara, M. Ito, K. Mise, and N. Kobayashi. 2011. Molecular characteristics of community-Acquired methicillin-resistant Staphylococcus aureus in Hokkaido, northern main island of Japan: Identification of sequence types 6 and 59 Panton-Valentine leucocidin-positive community-Acquired methicillin-resistant Staphylococcus aureus. Microb. Drug Resist. 17:241-250
16. Kennedy, A.D., M. Otto, K.R. Braughton, A.R. Whitney, L. Chen, B. Mathema, J.R. Mediavilla, K.A. Byrne, L.D. Parkins, F.C. Tenover, B.N. Kreiswirth, J.M. Musser, and F.R. DeLeo. 2008. Epidemic community-Associated methicillinresistant Staphylococcus aureus: Recent clonal expansion and diversification. Proc. Natl. Acad. Sci. U S A. 105:1327-1332
17. Kennedy, A.D., S.F. Porcella, C. Martens, A.R. Whitney, K.R. Braughton, L. Chen, C.T. Craig, F.C. Tenover, B.N. Kreiswirth, J.M. Musser, and F.R. DeLeo. 2010. Complete nucleotide sequence analysis of plasmids in strains of Staphylococcus aureus clone USA300 reveals a high level of identity among isolates with closely related core genome sequences. J. Clin. Microbiol. 48:4504-4511
18. Klevens, R.M., M.A. Morrison, J. Nadle, S. Petit, K. Gershman, S. Ray, L.H. Harrison, R. Lynfield, G. Dumyati, J.M. Townes, A.S. Craig, E.R. Zell, G.E. Fosheim, L.K. McDougal, R.B. Carey, and S.K. Fridkin. 2007. Invasive methicillin-resistant Staphylococcus aureus infections in the United States. JAMA 298:1763-1771
19. Kluytmans-Vandenbergh, M.F., and J.A. Kluytmans. 2006. Community-Acquired methicillin-resistant Staphylococcus aureus: Current perspectives. Clin. Microbiol. Infect. 12 Suppl 1:9-15
20. Kondo, Y., T. Ito, X.X. Ma, S. Watanabe, B.N. Kreiswirth, J. Etienne, and K. Hiramatsu. 2007. Combination of multiplex PCRs for staphylococcal cassette chromosome mec type assignment: Rapid identification system for mec, ccr, and major differences in junkyard regions. Antimicrob. Agents Chemother. 51:264-274
21. Manna, A.C., and A.L. Cheung. 2003. sarU, a sarA homolog, is repressed by SarT and regulates virulence genes in Staphylococcus aureus. Infect. Immun. 71:343-353
22. Milheirico, C., D.C. Oliveira, and H. de Lencastre. 2007. Multiplex PCR strategy for subtyping the staphylococcal cassette chromosome mec type IV in methicillin-resistant Staphylococcus aureus: 'SCCmec IV multiplex'. J. Antimicrob. Chemother. 60:42-48
23. Mine, Y., W. Higuchi, K. Taira, I. Nakasone, M. Tateyama, T. Yamamoto, H. Uezato, and K. Takahashi. 2011. Nosocomial outbreak of multidrug-resistant USA300 methicillinresistant Staphylococcus aureus causing severe furuncles and carbuncles in Japan. J. Dermatol. 38:1167-1171
24. Miragaia, M., H. de Lencastre, F. Perdreau-Remington, H.F. Chambers, J. Higashi, P.M. Sullam, J. Lin, K.I. Wong, K.A. King, M. Otto, G.F. Sensabaugh, and B.A. Diep. 2009. Genetic diversity of arginine catabolic mobile element in Staphylococcus epidermidis. PLoS One 4:e7722
25. Monecke, S., G. Coombs, A.C. Shore, D.C. Coleman, P. Akpaka, M. Borg, H. Chow, M. Ip, L. Jatzwauk, D. Jonas, K. Kadlec, A. Kearns, F. Laurent, F.G. O'Brien, J. Pearson, A. Ruppelt, S. Schwarz, E. Scicluna, P. Slickers, H.L. Tan, S. Weber, and R. Ehricht. 2011. A field guide to pandemic, epidemic and sporadic clones of methicillin-resistant Staphylococcus aureus. PLoS One 6:e17936
26. Nagao, M., Y. Iinuma, M. Suzuki, A. Matsushima, S. Takakura, Y. Ito, and S. Ichiyama. 2010. First outbreak of methicillin-resistant Staphylococcus aureus USA300 harboring the panton-valentine leukocidin genes among japanese health care workers and hospitalized patients. Am. J. Infect. Control 38:e37-e39
27. Rolo, J., M. Miragaia, A. Turlej-Rogacka, J. Empel, O. Bouchami, N.A. Faria, A. Tavares, W. Hryniewicz, A.C. Fluit, and H. de Lencastre; CONCORD Working Group. 2012. High genetic diversity among community-Associated Staphylococcus aureus in Europe: Results from a multicenter study. PLoS One 7:e34768
28. Shibuya, Y., M. Hara, W. Higuchi, T. Takano, Y. Iwao, and T. Yamamoto. 2008. Emergence of the community-Acquired methicillin-resistant Staphylococcus aureus USA300 clone in japan. J. Infect. Chemother. 14:439-441
29. Shopsin, B., M. Gomez, S.O. Montgomery, D.H. Smith, M. Waddington, D.E. Dodge, D.A. Bost, M. Riehman, S. Naidich, and B.N. Kreiswirth. 1999. Evaluation of protein A gene polymorphic region DNA sequencing for typing of Staphylococcus aureus strains. J. Clin. Microbiol. 37:3556-3563
30. Shore, A.C., O.M. Brennan, R. Ehricht, S. Monecke, S. Schwarz, P. Slickers, and D.C. Coleman. 2010. Identification and characterization of the multidrug resistance gene cfr in a Panton-Valentine leukocidin-positive sequence type 8 methicillin-resistant Staphylococcus aureus IVa (USA300) isolate. Antimicrob. Agents Chemother. 54:4978-4984
31. Shore, A.C., A.S. Rossney, O.M. Brennan, P.M. Kinnevey, H. Humphreys, D.J. Sullivan, R.V. Goering, R. Ehricht, S. Monecke, and D.C. Coleman. 2011. Characterization of a novel arginine catabolic mobile element (ACME) and staphylococcal chromosomal cassette mec composite island with significant homology to Staphylococcus epidermidis ACME type II in methicillin-resistant Staphylococcus aureus genotype ST22-MRSA-IV. Antimicrob. Agents Chemother. 55:1896-1905
32. Tenover, F.C., and R.V. Goering. 2009. Methicillin-resistant Staphylococcus aureus strain USA300: Origin and epidemiology. J. Antimicrob. Chemother. 64:441-446
33. Tenover, F.C., L.K. McDougal, R.V. Goering, G. Killgore, S.J. Projan, J.B. Patel, and P.M. Dunman. 2006. Characterization of a strain of community-Associated methicillinresistant Staphylococcus aureus widely disseminated in the United States. J. Clin. Microbiol. 44:108-118
34. Urushibara, N., M. Kawaguchiya, and N. Kobayashi. 2012. Two novel arginine catabolic mobile elements and staphylococcal chromosome cassette mec composite islands in community-Acquired methicillin-resistant Staphylococcus aureus genotypes ST5-MRSA-V and ST5-MRSA-II. J. Antimicrob. Chemother. 67:1828-1834
35. Yabe, S., T. Takano, W. Higuchi, S. Mimura, Y. Kurosawa, and T. Yamamoto. 2010. Spread of the community-Acquired methicillin-resistant Staphylococcus aureus USA300 clone among family members in Japan. J. Infect. Chemother. 16:372-374
36. Yamamoto, T., A. Nishiyama, T. Takano, S. Yabe, W. Higuchi, O. Razvina, and D. Shi. 2010. Community-Acquired methicillin-resistant Staphylococcus aureus: Community transmission, pathogenesis, and drug resistance. J. Infect. Chemother. 16:225-254
37. Zhang, K., J.A. McClure, S. Elsayed, T. Louie, and J.M. Conly. 2008. Novel multiplex PCR assay for simultaneous identification of community-Associated methicillin-resistant Staphylococcus aureus strains USA300 and USA400 and detection of mecA and panton-valentine leukocidin genes, with discrimination of Staphylococcus aureus from coagulasenegative staphylococci. J. Clin. Microbiol. 46:1118-1122