Screening and analyzing the potential bioactive components from reduning injection, using macrophage cell extraction and ultra-high performance liquid chromatography coupled with mass spectrometry

American Journal of Chinese Medicine

Volumn 41, Issue 1, 2013, Pages 221-229

  Li, Yonghui ^a,b   Wang, Peixiang ^c   Xiao, Wei ^a,c   Zhao, Li ^c   Wang, Zhenzhong ^a,c   Yu, Li ^d  

^a State Key Laboratory of New tech for Chinese Medicine Pharmaceutical Process   (China)

^b HAINAN MEDICAL UNIVERSITY   (China)

^c JIANGSU KANION PHARMACEUTICAL CO   (China)

^d NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Bioactive Components; Macrophage Extraction; RDN Injection; UPLC MS

Indexed keywords

3,4 DICAFFEOYLQUINIC ACID; CHINESE DRUG; CHLOROGENIC ACID; INTERLEUKIN 6; ISOCHLOROGENIC ACID; LIPOPOLYSACCHARIDE; PROSTAGLANDIN E2; REDUNING; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL PROTECTION; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG SCREENING; IN VITRO STUDY; MACROPHAGE; MACROPHAGE CELL EXTRACTION; MOUSE; NONHUMAN; PROSTAGLANDIN RELEASE; PROSTAGLANDIN SYNTHESIS INHIBITION; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; CHLOROGENIC ACID; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DINOPROSTONE; DRUGS, CHINESE HERBAL; INFLAMMATION MEDIATORS; INJECTIONS; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MASS SPECTROMETRY; MICE;

EID: 84872959548     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X1350016X     Document Type: Article

References (16)

1. Bi, Y.A., Z.Z. Wang, A.H. Song, T. Liu, X.H. Fu and W. Xiao. The fingerprint research and multicomponent qualitative analysis of Reduning injection via HPLC. World Sci. Technol./Modern Tradit. Chin. Med. Mater. Med. 12: 298-303, 2010
2. Huang, X.M., Y.J. Liu, Y.Z. He, F.F. Chen and Y.K. Wang. Clinical observation of Reduning injection in treatment of patients with acute upper respiratory tract infections. Chin. J. Clin Pharmacol. Ther. 11: 470-473, 2006
3. Kim, M.C., D.S. Kim, S.J. Kim, J. Park, H.L. Kim, S.Y. Kim, K.S. Ahn, H.J. Jang, S.G. Lee, K.M. Lee, S.H. Hong and J.Y. Um. Eucommiae cortex inhibits TNF- and IL-6 through the suppression of caspase-1 in lipopolysaccharide- stimulated mouse peritoneal macrophages Am. J. Chin. Med. 40: 135-149, 2012
4. Kozak, W., M.J. Kluger, D. Soszynski, C.A. Conn, K. Rudolph, L.R. Leon and H. Zheng. IL-6 and IL-1β in fever: Studies using cytokine-deficient (knockout) mice. Ann. N. Y. Acad. Sci. 856: 33-47, 1998
5. LeMay, L.G., A.J. Vander and M.J. Kluger. Role of interleukin 6 in fever in rats. Am. J. Physiol. 258: 798-803, 1990
6. Li, S.L., P. Li, L.H. Sheng, R.Y. Li, L.W. Qi and L.Y. Zhang. Live cell extraction and HPLC-MS analysis for predicting bioactive components of traditional Chinese medicines. J. Pharm Biomed. Anal. 41: 576-581, 2006
7. Meng, X.L., H.W. Li, Y. Li, Q. Yu, L.L. Wan and C. Guo. Advances in studies on chemical constituents and pharmacological activities of Gardenia jasminoides. Chin. J. New Drug 20: 959-967, 2011
8. Shao, Q.M. and J.J. Yan. Efficacy observation of reduning injection in treating hand, foot and mouth disease (HFMD) in 200 cases of children. China Modern Doctor 49: 31-32, 2011
9. Su, S.L., L. Yu, Y.Q. Hua, J.A. Duan, H.S. Deng, Y.P. Tang, Y. Lu and A.W. Ding. Screening and analyzing the potential bioactive components from Shaofu Zhuyu decoction, using human umbilical vein endothelial cell extraction and high-performance liquid chromatography coupled with mass spectrometry. Biomed. Chromatogr. 22: 1385-1392, 2008
10. Sun, L.M., X.C. Chang, R.B. Zhao, Y.L. Cui and L.J. Wang. Reduning treatment of children with herpes angina efficacy. China Med. Herald 8: 149-150, 2011
11. Sundgren-Andersson, A.K., P. Ostlund and T. Bartfai. IL-6 is essential in TNF-induced fever. Am. J. Physiol. 275: 2028-2034, 1998
12. Ushiroyama, T., N. Yokoyama, M. Hakukawa, K. Sakuma, F. Ichikawa and S. Yoshida. Clinical efficacy of macrophage-activating Chinese mixed herbs (MACH) in improvement of embryo qualities in women with long-term infertility of unknown etiology. Am. J. Chin. Med. 40: 1-10, 2012
13. Wu, Y.H., Y.C. Wei, Y.S. Tai, K.J. Chen and H.Y. Li. Clinical outcomes of traditional Chinese medicine compound formula in treating sleep-disordered breathing patients. Am. J. Chin. Med 11-24, 2012
14. Yu, S.L., L. Zhang and L. Sun. Flos lonicerae's research progress. Lishizhen Med. Mater. Med. Res 498-500, 2002
15. Yu, L., J. Zhao, Q. Zhu and S.P. Li. Macrophage biospecial extraction and high performance liquid chromatography for hypothesis of immunological active components in Cordyceps sinensis J. Pharm. Biomed. Anal. 44: 439-443, 2007
16. Zhang, Y. The clinical efficacy of reduning in the treatment of HFMD. Guide China Med. 9: 33-34, 2011