25-hydroxyvitamin D testing: Challenging the performance of current automated immunoassays

Clinical Chemistry and Laboratory Medicine

Volumn 50, Issue 11, 2012, Pages 1953-1963

  Farrell, Chris ^a   Soldo, Joshua ^b   Williams, Paul ^c,d   Herrmann, Markus ^a,c,e  

^a Laverty Pathology   (Australia)

^b Diasorin SpA   (Italy)

^c UNIVERSITY OF SYDNEY   (Australia)

^d ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^e CENTRAL HOSPITAL OF BOLZANO   (Italy)

Author keywords

25 hydroxyvitamin D; C3 epimer; Immunoassays; Liquid chromatography tandem mass spectrometry

Indexed keywords

25 HYDROXYVITAMIN D; HETEROPHILE ANTIBODY; IMMUNOGLOBULIN G ANTIBODY;

ACCURACY; ADULT; ARTICLE; AUTOMATION; BLOOD SAMPLING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EPIMER; HUMAN; HUMAN EXPERIMENT; IMMUNOASSAY; INTERMETHOD COMPARISON; LIQUID CHROMATOGRAPHY; MEASUREMENT REPEATABILITY; NORMAL HUMAN; PERFORMANCE; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

ADULT; AUTOMATION; BLOOD CHEMICAL ANALYSIS; HUMANS; IMMUNOASSAY; REFERENCE VALUES; STEREOISOMERISM; VITAMIN D;

EID: 84872927167     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/cclm-2012-0522     Document Type: Article

References (31)

1. Hollis BW. Assessment and interpretation of circulating 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D in the clinical environment. Endocrinol Metab Clin N Am 2010;39:271 - 86.
2. Hollis BW. Assessment of vitamin D status and definition of a normal circulating range of 25-hydroxyvitamin D. Curr Opin Endocrinol Diabetes Obes 2008;15:489 - 94.
3. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2011;96:1911 - 30.
4. Nowson CA, McGrath JJ, Ebeling PR, Haikerwal A, Daly RM, Sanders KM, et al. Vitamin D and health in Australia and New Zealand: a position statement. Med J Aust 2012;196:686 - 7.
5. Sai AJ, Walters RW, Fang X, Gallagher JC. Relationship between vitamin D, parathyroid hormone and bone health. J Clin Endocrinol Metab 2011;96:E436 - 46.
6. Marcocci C, Cetani F. Primary hyperparathyroidism. N Engl J Med 2011;365:2389 - 97.
7. Eastell R, Arnold A, Brandi ML, Brown EM, D'Amour P, Hanley DA, et al. Diagnosis of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop. J Clin Endocrinol Metab 2009;94:340 - 50.
8. Krasowski MD. Pathology consultation on vitamin D testing. Am J Clin Pathol 2011;136:507 - 14.
9. Lau SL, Gunton JE, Athayde NP, Byth K, Cheung NW. Serum 25-hydroxyvitamin D and glycated haemoglobin levels in women with gestational diabetes mellitus. Med J Aust 2011;194:334 - 7.
10. Robinson CL, Alanis MC, Wagner CL, Hollis BW, Johnson DD. Plasma 25-hydroxyvitamin D levels in early-onset severe preeclampsia. Am J Obstet Gynecol 2010;203:366.e1 - 6.
11. Samoszuk M, Leuther M, Hoyle N. Role of serum P1NP measurement for monitoring treatment response in osteoporosis. Biomark Med 2008;5:495 - 508.
12. Holick MF. Vitamin D deficiency. N Engl J Med 2007;357:266 - 81.
13. Grant WB, Holick MF. Benefits and requirements of vitamin D for optimal health: a review. Alt Med Rev 2005;10:94 - 111.
14. Holick MF. Vitamin D: the underappreciated D-lightful hormone that is important for skeletal and cellular health. Curr Opin Endocrinol Diabetes Obes 2002;9:87 - 98.
15. Farrell CL, Martin S, McWhinney B, Straub I, Williams P, Herrmann M. State-of-the-art vitamin D assays: a comparison of automated immunoassays with liquid chromatography-tandem mass spectrometry methods. Clin Chem 2012;58:531 - 42.
16. Janssen MJ, Wielders JP, Bekker CC, Boesten LS, Buijs MM, Heijboer AC, et al. Multicenter comparison study of current methods to measure 25-hydroxyvitamin D in serum. Ned Tijdschr Klin Chem Labgeneesk 2012;37:223 - 6.
17. Ong L, Saw S, Sahabdeen NB, Tey KT, Ho CS, Sethi SK. 25-Hydroxyvitamin D assays: do they pass the test ? Clin Chim Acta 2012;413:1127 - 34.
18. Moon HW, Cho JH, Hur M, Song J, Oh GY, Park CM, et al. Comparison of four current 25-hydroxyvitamin D assays. Clin Biochem 2012;45:326 - 30.
19. Carter DG. 25-Hydroxyvitamin D: a difficult analyte. Clin Chem 2012;58:486 - 8.
20. Heijboer AC, Blankenstein MA, Kema IP, Buijs MM. Accuracy of 6 routine 25-hydroxyvitamin D assays: influence of vitamin D binding protein concentration. Clin Chem 2012;58:543 - 8.
21. Cavalier E, Carlisi A, Bekaert AC, Rousselle O, Chapelle JP. Human anti-animal interference in DiaSorin Liaison total 25(OH)-vitamin D assay: towards the end of a strange story ? Clin Chim Acta 2012;413:527 - 8.
22. Singh RJ, Taylor RL, Reddy GS, Grebe SK. C-3 epimers can account for a significant proportion of total circulating 25-hydroxyvitamin D in infants, complicating accurate measurement and interpretation of vitamin D status. J Clin Endocrinol Metab 2006;91:3055 - 61.
23. Lu CM. Pathology consultation on vitamin D testing: clinical indications for 25(OH) vitamin D measurement. Am J Clin Pathol 2012;137:831 - 2.
24. Lai JK, Lucas RM, Clements MS, Harrison SL, Banks E. Assessing vitamin D status: pitfalls for the unwary. Mol Nutr Food Res 2010;54:1062 - 71.
25. Carter GD. Accuracy of 25-hydroxyvitamin D assays: confronting the issues. Curr Drug Targets 2011;12:19 - 28.
26. Yates AM, Bowron A, Calton L, Heynes J, Field H, Rainbow S, et al. Interlaboratory variation in 25-hydroxyvitamin D 2 and 25-hydroxyvitamin D 3 is significantly improved if common calibration material is used. Clin Chem 2008;54:2082 - 4.
27. Phinney KW, Bedner M, Tai SS, Vamathevan VV, Sander LC, Sharpless KE, et al. Development and certification of a standard reference material for vitamin D metabolites in human serum. Anal Chem 2010;84:956 - 62.
28. Bedner M, Phinney KW. Development and comparison of three liquid chromatography-atmospheric pressure chemical ionization/mass spectrometry methods for determining vitamin D metabolites in human serum. J Chromatogr A 2012;1240:132 - 9.
29. Tai SS, Bedner M, Phinney KW. Development of a candidate reference measurement procedure for the determination of 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 in human serum using isotope-dilution liquid chromatography-tandem mass spectrometry. Anal Chem 2010;82:1942 - 8.
30. Fraser CG. Biological variation from principles to practice. Washington (DC): AACC Press, 2001.
31. Viljoen A, Singh DK, Farrington K, Twomey PJ. Analytical quality goals for 25-vitamin D based on biological variation. J Clin Lab Anal 2011;25:130 - 3.