State-of-the-art vitamin D assays: A comparison of automated immunoassays with liquid chromatography-tandem mass spectrometry methods

Clinical Chemistry

Volumn 58, Issue 3, 2012, Pages 531-542

  Farrell, Christopher John L ^a,b   Martin, Steven ^a   McWhinney, Brett ^c   Straub, Isabella ^d   Williams, Paul ^e   Herrmann, Markus ^a,d  

^a Laverty Pathology   (Australia)

^b ROYAL NORTH SHORE HOSPITAL   (Australia)

^c Pathology Queensland   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

^e UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIFEDIOL;

ARTICLE; AUTOMATED IMMUNOASSAY; BLOOD SAMPLING; CONTROLLED STUDY; IMMUNOASSAY; LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY; VITAMIN BLOOD LEVEL;

AUTOMATION; CHROMATOGRAPHY, LIQUID; HUMANS; IMMUNOASSAY; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; VITAMIN D;

EID: 84857866069     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2011.172155     Document Type: Article

References (28)

1. Holick MF. Vitamin D deficiency. N Engl J Med 2007;357:266-81.
2. Rosen CJ. Clinical practice: vitamin D insufficiency. N Engl J Med 2011;364:248-54.
3. Medical Benefits Rev Task Group. Review of the funding arrangements for pathology services. http://www.health.gov.au/internet/main/publishing.nsf/ Content/A7F7F7F944757607CA2576A2001C1725/ $File/ Pathology%20Review%20Discussion%20Paper. pdf (Accessed December 2011).
4. DeLuca HF. Overview of general physiologic features and functions of vitamin D. Am J Clin Nutr 2004;80:1689S-96S.
5. Holick MF, Biancuzzo RM, Chen TC, Klein EK, Young A, Bibuld D, et al. Vitamin D2 is as effective as vitamin D3 in maintaining circulating concentrations of 25-hydroxyvitamin D. J Clin Endocrinol Metab 2008;93:677-81. (Pubitemid 351398538)
6. Clemens TL, Zhou XY, Myles M, Endres D, Lindsay R. Serum vitamin D2 and vitamin D3 metabolite concentrations and absorption of vitamin D2 in elderly subjects. J Clin Endocrinol Metab 1986; 63:656-60. (Pubitemid 16050566)
7. Leventis P, Kiely PD. The tolerability and biochemical effects of high-dose bolus vitamin D2 and D3 supplementation in patients with vitamin D insufficiency. Scand J Rheumatol 2009;38:149-53.
8. Romagnoli E, Mascia ML, Cipriani C, Fassino V, Mazzei F, D'Erasmo E, et al. Short and long-term variations in serum calciotropic hormones after a single very large dose of ergocalciferol (vitamin D2) or cholecalciferol (vitamin D3) in the elderly. J Clin Endocrinol Metab 2008;93:3015-20.
9. Herrmann M, Williams P. Measurement of vitamin D. In: Herrmann W, Obeid R, eds. Vitamins in the prevention of human disease. 1st ed. Berlin/New York: Walter de Gruyter GmbH & Co KG; 2011. P 395-9.
10. Hart GR, Furniss JL, Laurie D, Durham SK. Measurement of vitamin D status: background, clinical use, and methodologies. Clin Lab 2006;52: 335-43. (Pubitemid 44336214)
11. Lensmeyer GL, Wiebe DA, Binkley N, Drezner MK. HPLC method for 25-hydroxyvitamin D measurement: comparison with contemporary assays. Clin Chem 2006;52:1120-6. (Pubitemid 43794425)
12. Herrmann M, Harwood T, Gaston-Parry O, Kouzios D, Wong T, Lih A, et al. A new quantitative LC tandem mass spectrometry assay for serum 25-hydroxy vitamin D. Steroids 2010;75:1106-12.
13. Glendenning P, Taranto M, Noble JM, Musk AA, Hammond C, Goldswain PR, et al. Current assays overestimate 25-hydroxyvitamin D3 and underestimate 25-hydroxyvitamin D2 compared with HPLC: need for assay-specific decision limits and metabolite-specific assays. Ann Clin Biochem 2006;43:23-30. (Pubitemid 43105054)
14. Christakos S, Ajibade DV, Dhawan P, Fechner AJ, Mady LJ. Vitamin D: metabolism. Endocrinol Metab Clin North Am 2010;39:243-53.
15. Tai SS, Bedner M, Phinney KW. Development of a candidate reference measurement procedure for the determination of 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 in human serum using isotope-dilution liquid chromatography-tandem mass spectrometry. Anal Chem 2010;82:1942-8.
16. Stepman HC, Vanderroost A, Van Uytfanghe K, Thienpont LM. Candidate reference measurement procedures for serum 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 by using isotope-dilution liquid chromatography-tandem mass spectrometry. Clin Chem 2011;57:441-8.
17. Binkley N, Krueger DC, Morgan S, Wiebe D. Current status of clinical 25-hydroxyvitamin D measurement: an assessment of between-laboratory agreement. Clin Chim Acta 2010;411: 1976-82.
18. Liao JJ, Lewis JW. A note on concordance correlation coefficient. PDA J Pharm Sci Technol 2000; 54:23-6. (Pubitemid 30183797)
19. Lin LI. A concordance correlation coefficient to evaluate reproducibility. Biometrics 1989;45: 255-68.
20. Passing H, Bablok. A new biometrical procedure for testing the equality of measurements from two different analytical methods. Application of linear regression procedures for method comparison studies in clinical chemistry, Part I. J Clin Chem Clin Biochem 1983;21:709-20. (Pubitemid 14208512)
21. Fraser CG. Biological variation: from principles to practice. Washington (DC): AACC Press; 2001.
22. Viljoen A, Singh DK, Farrington K, Twomey PJ. Analytical quality goals for 25-vitamin D based on biological variation. J Clin Lab Anal 2011;25:130-3.
23. Holick MF, Binkley NC, Bischoff-Ferrari H, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: An endocrine society clinical practice guideline. J Clin Endocrinol Metab 2011; 96:1911-30.
24. Carter GD, Jones JC. Use of a common standard improves the performance of liquid chromatography-tandem mass spectrometry methods for serum 25-hydroxyvitamin-D. Ann Clin Biochem 2009;46:79-81.
25. Singh RJ, Taylor RL, Reddy GS, Grebe SKG. C-3 epimers can account for a significant proportion of total circulating 25-hydroxyvitamin D in infants, complicating accurate measurement and interpretation of vitamin D status. J Clin Endocrinol Metab 2006;91:3055-61. (Pubitemid 44271755)
26. Stepman HCM, Vanderrost A, Stöckl D, Thienpont LM. Full-scan mass spectral evidence for 3-epi-25-hydroxyvitamin D3 in serum of infants and adults. Clin Chem Lab Med 2011;49:253-6.
27. Lewis JG, Elder PA. Serum 25-OH vitamin D2 and D3 are stable under exaggerated conditions. Clin Chem 2008;54:1931-2.
28. Antoniucci DM, Black DM, Sellmeyer DE. Serum 25-hydroxyvitamin D is unaffected by multiple freeze-thaw cycles. Clin Chem 2005;51:258-61. (Pubitemid 40024054)