The renal injury and inflammation caused by ischemia-reperfusion are reduced by genetic inhibition of TNF-αR1: A comparison with infliximab treatment

European Journal of Pharmacology

Volumn 700, Issue 1-3, 2013, Pages 134-146

  Di Paola, Rosanna ^a   Genovese, Tiziana ^a   Impellizzeri, Daniela ^a   Ahmad, Akbar ^a   Cuzzocrea, Salvatore ^a,b   Esposito, Emanuela ^a  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Inflammation; Renal ischemia reperfusion injury; TNF R1 gene deletion

Indexed keywords

3 NITROTYROSINE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; CREATININE; CYCLOOXYGENASE 2; FAS LIGAND; GAMMA GLUTAMYLTRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INFLIXIMAB; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; MALONALDEHYDE; MYELOPEROXIDASE; PADGEM PROTEIN; PROTEIN BAX; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL INFILTRATION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG INHIBITION; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME REGULATION; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GENE; GENE DELETION; GENE INACTIVATION; HISTOLOGY; INTRACELLULAR SIGNALING; KIDNEY ARTERY STENOSIS; KIDNEY BIOPSY; KIDNEY FUNCTION; KIDNEY INJURY; LIPID PEROXIDATION; MALE; MOUSE; NEPHRITIS; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPERFUSION INJURY; TNF ALPHA R1 GENE; TREATMENT RESPONSE; UREA BLOOD LEVEL;

ACUTE KIDNEY INJURY; ANIMALS; ANTIBODIES, MONOCLONAL; APOPTOSIS; BIOLOGICAL MARKERS; CELL ADHESION MOLECULES; GENE DELETION; GENE EXPRESSION REGULATION; GENE KNOCKOUT TECHNIQUES; INFLAMMATION; INTERLEUKIN-1BETA; KIDNEY; LIPID PEROXIDATION; MALE; MICE; NEUTROPHIL INFILTRATION; OXIDATIVE STRESS; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; REPERFUSION INJURY; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE;

EID: 84872921643     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.11.066     Document Type: Article

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