Adaptive control of epileptiform excitability in an in vitro model of limbic seizures

Experimental Neurology

Volumn 241, Issue 1, 2013, Pages 179-183

  Panuccio, Gabriella ^a   Guez, Arthur ^b   Vincent, Robert ^c   Avoli, Massimo ^a   Pineau, Joelle ^c  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Closed loop strategy; Deep brain stimulation; Epilepsy

Indexed keywords

ADULT ANIMAL; ANIMAL TISSUE; ARTICLE; BRAIN DEPTH STIMULATION; BRAIN SLICE; COMPLEX PARTIAL SEIZURE; CONTROLLED STUDY; DISEASE CONTROL; ENTORHINAL CORTEX; EPILEPTIC DISCHARGE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SUBICULUM;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; BIOPHYSICS; ELECTRIC STIMULATION; EVOKED POTENTIALS; LIMBIC SYSTEM; NEURAL PATHWAYS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84872856940     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.01.002     Document Type: Article

References (26)

1. Avoli M., Barbarosie M., Lucke A., Nagao T., Lopantsev V., Kohling R. Synchronous GABA-mediated potentials and epileptiform discharges in the rat limbic system in vitro. J. Neurosci. 1996, 16:3912-3924.
2. Avoli M., D'Antuono M., Louvel J., Kohling R., Biagini G., Pumain R., D'Arcangelo G., Tancredi V. Network and pharmacological mechanisms leading to epileptiform synchronization in the limbic system in vitro. Prog. Neurobiol. 2002, 68:167-207.
3. Barbarosie M., Avoli M. CA3-driven hippocampal-entorhinal loop controls rather than sustains in vitro limbic seizures. J. Neurosci. 1997, 17:9308-9314.
4. Boon P., Vonck K., De Herdt V., Van Dycke A., Goethals M., Goossens L., Van Zandijcke M., De Smedt T., Dewaele I., Achten R., Wadman W., Dewaele F., Caemaert J., Van Roost D. Deep brain stimulation in patients with refractory temporal lobe epilepsy. Epilepsia 2007, 48:1551-1560.
5. Bush K., Pineau J. Manifold embeddings for model-based reinforcement learning under partial observability. Advances in Neural Information Processing Systems 2009, 189-197. Y. Bengio, D. Schuurmans, J. Lafferty, C.K.I. Williams, A. Culotta (Eds.).
6. Bush K., Panuccio G., Avoli M., Pineau J. Evidence-based modeling of network discharge dynamics during periodic pacing to control epileptiform activity. J. Neurosci. Methods 2012, 204:318-325.
7. Cohen-Gadol A.A., Stoffman M.R., Spencer D.D. Emerging surgical and radiotherapeutic techniques for treating epilepsy. Curr. Opin. Neurol. 2003, 16:213-219.
8. D'Arcangelo G., Panuccio G., Tancredi V., Avoli M. Repetitive low-frequency stimulation reduces epileptiform synchronization in limbic neuronal networks. Neurobiol. Dis. 2005, 19:119-128.
9. Durand M.D., Bikson M. Suppression and control of epileptiform activity by electrical stimulation: a review. Proc. IEEE 2001, 89:1065-1082.
10. Ellis T.L., Stevens A. Deep brain stimulation for medically refractory epilepsy. Neurosurg. Focus 2008, 25:E11.
11. Fountas K.N., Smith J.R., Murro A.M., Politsky J., Park Y.D., Jenkins P.D. Implantation of a closed-loop stimulation in the management of medically refractory focal epilepsy: a technical note. Stereotact. Funct. Neurosurg. 2005, 83:153-158.
12. Geurts P., Ernst D., Wehenkel L. Extremely randomized trees. Mach. Learn. 2006, 63:3-42.
13. Guez A., Vincent R.D., Avoli M., Pineau J. Adaptive treatment of epilepsy via batch-mode reinforcement learning. Proceedings of the Twentieth Innovative Applications of Artificial Intelligence Conference 2008, 1671-1678.
14. Hamani C., Andrade D., Hodaie M., Wennberg R., Lozano A. Deep brain stimulation for the treatment of epilepsy. Int. J. Neural Syst. 2009, 19:213-226.
15. Kossoff E.H., Ritzl E.K., Politsky J.M., Murro A.M., Smith J.R., Duckrow R.B., Spencer D.D., Bergey G.K. Effect of an external responsive neurostimulator on seizures and electrographic discharges during subdural electrode monitoring. Epilepsia 2004, 45:1560-1567.
16. Kotsopoulos I.A., van Merode T., Kessels F.G., de Krom M.C., Knottnerus J.A. Systematic review and meta-analysis of incidence studies of epilepsy and unprovoked seizures. Epilepsia 2002, 43:1402-1409.
17. Kwan P., Brodie M.J. Early identification of refractory epilepsy. N. Engl. J. Med. 2000, 342:314-319.
18. Loscher W., Schmidt D. New horizons in the development of antiepileptic drugs: the search for new targets. Epilepsy Res. 2004, 60:77-159.
19. Marks W.J. Deep brain stimulation in epilepsy. Deep Brain Stimulation in Neurological and Psychiatric Disorders 2008, 561-569. Humana Press, New York. D. Tarsy, J.L. V., P. Starr, M. Okun (Eds.).
20. Nakagawa M., Durand D. Suppression of spontaneous epileptiform activity with applied currents. Brain Res. 1991, 567:241-247.
21. Osorio I., Frei M.G., Sunderam S., Giftakis J., Bhavaraju N.C., Schaffner S.F., Wilkinson S.B. Automated seizure abatement in humans using electrical stimulation. Ann. Neurol. 2005, 57:258-268.
22. Panuccio G., D'Antuono M., de Guzman P., De Lannoy L., Biagini G., Avoli M. In vitro ictogenesis and parahippocampal networks in a rodent model of temporal lobe epilepsy. Neurobiol. Dis. 2010, 39:372-380.
23. Pineau J., Guez A., Vincent R., Panuccio G., Avoli M. Treating epilepsy via adaptive neurostimulation: a reinforcement learning approach. Int. J. Neural Syst. 2009, 19:227-240.
24. Schiff S.J., Jerger K., Duong D.H., Chang T., Spano M.L., Ditto W.L. Controlling chaos in the brain. Nature 1994, 370:615-620.
25. Schiller Y., Bankirer Y. Cellular mechanisms underlying antiepileptic effects of low- and high-frequency electrical stimulation in acute epilepsy in neocortical brain slices in vitro. J. Neurophysiol. 2007, 97:1887-1902.
26. Theodore W.H., Fisher R.S. Brain stimulation for epilepsy. Lancet Neurol. 2004, 3:111-118.