Long-term channelrhodopsin-2 (ChR2) expression can induce abnormal axonal morphology and targeting in cerebral cortex

Frontiers in Neural Circuits

Volumn , Issue JAN, 2013, Pages

  Miyashita, Toshio ^a,b   Shao, Ray ^a   Chung, Jason ^a   Pourzia, Olivia ^a   Feldman, Dan E ^a  

^a University of California Berkeley   (United States)

^b NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

Author keywords

Axon development; Circuit; In utero electroporation; Optogenetics

Indexed keywords

ADENOVIRUS VECTOR; ALPHA CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CHANNELRHODOPSIN 2; ENHANCED YELLOW FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; RHODOPSIN; UNCLASSIFIED DRUG; YELLOW FLUORESCENT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AXONAL ABNORMALITY; CAG REPEAT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPATHOLOGY; DENDRITIC CELL; ELECTROPORATION; EMBRYO; EVOKED RESPONSE; FEMALE; IN UTERO DNA ELECTROPORATION; IN VITRO STUDY; IN VIVO STUDY; NERVE CELL MEMBRANE POTENTIAL; NERVE FIBER; NEUROPATHOLOGY; NONHUMAN; OPTOGENETICS; PERIKARYON; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN TARGETING; PYRAMIDAL NERVE CELL; RAT; SOMATOSENSORY CORTEX; VIRAL GENE DELIVERY SYSTEM;

EID: 84872850382     PISSN: 16625110     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncir.2013.00008     Document Type: Article

References (29)

1. Gordon, M., and O'neill, W.E. (2000). An extralemniscal component of the mustache bat inferior colliculus selective for direction and rate of linear frequency modulations. J Comp Neurol 426, 165-181.
2. Hage, S.R., and Ehret, G. (2003). Mapping responses to frequency sweeps and tones in the inferior colliculus of house mice. Eur J Neurosci 18, 2301-2312.
3. Holy, T.E., and Guo, Z. (2005). Ultrasonic songs of male mice. PLoS Biol 3, e386.
4. Kanwal, J.S., Matsumura, S., Ohlemiller, K., and Suga, N. (1994). Analysis of acoustic elements and syntax in communication sounds emitted by mustached bats. J Acoust Soc Am 96, 1229-1254.
5. Kitamura, K., Judkewitz, B., Kano, M., Denk, W., and Häusser, M. (2008). Targeted patch-clamp recordings and single-cell electroporation of unlabeled neurons in vivo. Nat Methods 5, 61-67.
6. Kuo, R.I., and Wu, G.K. (2012). The generation of direction selectivity in the auditory system. Neuron 73, 1016-1027.
7. Lorteije, J.A.M., and Borst, J.G.G. (2011). Contribution of the mouse calyx of Held synapse to tone adaptation. Eur J Neurosci 33, 251-258.
8. Lui, B., and Mendelson, J.R. (2003). Frequency modulated sweep responses in the medial geniculate nucleus. Exp Brain Res 153, 550-553.
9. Malmierca, M.S., Cristaudo, S., Pérez-González, D., and Covey, E. (2009). Stimulus specific adaptation in the inferior colliculus of the anesthetized rat. J Neurosci 29, 5483-5493.
10. Phillips, D.P., Mendelson, J.R., Cynader, M.S., and Douglas, R.M. (1985). Responses of single neurones in cat auditory cortex to time-varying stimuli: frequency modulated tones of narrow excursion. Exp Brain Res 58, 443-454.
11. Pollak, G.D., Xie, R., Gittelman, J.X., Andoni, S., and Li, N. (2011). The dominance of inhibition in the inferior colliculus. Hear Res 274, 27-39.
12. Poon, P.W.F., Chen, X., and Cheung, Y.M. (1992). Differences in FM response correlate with morphology of neurons in the rat inferior colliculus. Exp Brain Res 91, 94-104.
13. Poon, P.W.F., Chen, X., and Hwang, J.C. (1991). Basic determinants for FM responses in the inferior colliculus of rats. Exp Brain Res 83, 598-606.
14. Razak, K.A., and Fuzessery, Z.M. (2008). Facilitatory mechanisms underlying selectivity for the direction and rate of frequency modulated sweeps in the auditory cortex. J Neurosci 28, 9806-9816.
15. Ryan, M.J. (1983). Frequency modulated calls and species recognition in a neotropical frog. Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology 150, 217-221.
16. Siemers, B.M., Schauermann, G., Turni, H., and Von Merten, S. (2009). Why do shrews twitter? Communication or simple echo-based orientation. Biol Lett 5, 593-596.
17. Simmons, J.A., and Stein, R.A. (1980). Acoustic imaging in bat sonar: Echolocation signals and the evolution of echolocation. Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology 135, 61-84.
18. Stein, R.C. (1968). Modulation in bird sounds. The Auk 85, 229-243.
19. Stiebler, I., Neulist, R., Fichtel, I., and Ehret, G. (1997). The auditory cortex of the house mouse: left-right differences, tonotopic organization and quantitative analysis of frequency representation. J Comp Physiol A 181, 559-571.
20. Suga, N. (1965). Analysis of frequency-modulated sounds by auditory neurones of echo1027-locating bats. J Physiol 179, 26-53.
21. Suga, N., and Schlegel, P. (1973). Coding and processing in the auditory systems of FM1030 signal-producing bats. J Acoust Soc Am 54, 174-190.
22. Voytenko, S.V., and Galazyuk, A.V. (2007). Intracellular recording reveals temporal integration in inferior colliculus neurons of awake bats. J Neurophysiol 97, 1368-1378.
23. Whitfield, I.C., and Evans, E.F. (1965). Responses of auditory cortical neurons to stimuli of changing frequency. J Neurophysiol 28, 655-672.
24. Williams, A.J., and Fuzessery, Z.M. (2010). Facilitatory mechanisms shape selectivity for the rate and direction of FM sweeps in the inferior colliculus of the pallid bat. J Neurophysiol 104, 1456-1471.
25. Williams, A.J., and Fuzessery, Z.M. (2011). Differential roles of GABAergic and glycinergic input on FM selectivity in the inferior colliculus of the pallid bat. J Neurophysiol 106, 2523-2535.
26. Williams, A.J., and Fuzessery, Z.M. (2012). Multiple mechanisms shape FM sweep rate selectivity: complementary or redundant? Front Neural Circuits 6, 54.
27. Ye, C.-Q., Poo, M.-M., Dan, Y., and Zhang, X.-H. (2010). Synaptic mechanisms of direction selectivity in primary auditory cortex. J Neurosci 30, 1861-1868.
28. Zeng, F.G., Nie, K., Stickney, G.S., Kong, Y.Y., Vongphoe, M., Bhargave, A., Wei, C., and Cao, K. (2005). Speech recognition with amplitude and frequency modulations. Proc Natl Acad Sci U S A 102, 2293-2298.
29. Zhang, L.I., Tan, A.Y.Y., Schreiner, C.E., and Merzenich, M.M. (2003). Topography and synaptic shaping of direction selectivity in primary auditory cortex. Nature 424, 201-205.