Is selective lymphadenectomy more cost-effective than routine lymphadenectomy in patients with endometrial cancer?

Gynecologic Oncology

Volumn 128, Issue 2, 2013, Pages 166-170

  Clements, A E ^a   Tierney, B J ^a   Cohn, D E ^a   Straughn Jr , J M ^b  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Cost effectiveness; Endometrial; Lymphadenectomy; Lymphedema

Indexed keywords

ANTINEOPLASTIC AGENT;

ADULT; ARTICLE; BRACHYTHERAPY; CANCER CHEMOTHERAPY; CANCER GRADING; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SIZE; COHORT ANALYSIS; COST EFFECTIVENESS ANALYSIS; ENDOMETRIUM CANCER; FEMALE; HEALTH CARE COST; HUMAN; INTERMETHOD COMPARISON; LYMPH NODE DISSECTION; LYMPHEDEMA; MAJOR CLINICAL STUDY; MEDICAL FEE; MEDICARE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RISK FACTOR; ROUTINE LYMPHADENECTOMY; SELECTIVE LYMPHADENECTOMY; SENSITIVITY ANALYSIS; TREATMENT PLANNING; UNITED STATES; VAGINAL BRACHYTHERAPY;

COST-BENEFIT ANALYSIS; DECISION SUPPORT TECHNIQUES; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; LYMPH NODE EXCISION; LYMPH NODES; LYMPHATIC METASTASIS; NEOPLASM STAGING; RISK FACTORS; UNITED STATES;

EID: 84872847662     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2012.10.007     Document Type: Article

References (30)

1. Available from: http://seer.cancer.gov/statfacts/html/corp.html
2. S. Pecorelli Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium Int J Gynaecol Obstet 105 2 2009 103 104 (Epub 2009/04/16)
3. W.T. Creasman, C.P. Morrow, B.N. Bundy, H.D. Homesley, J.E. Graham, and P.B. Heller Surgical pathologic spread patterns of endometrial cancer. A Gynecologic Oncology Group Study Cancer 60 8 Suppl. 1987 2035 2041 (Epub 1987/10/15) (Pubitemid 17145924)
4. P.B. Panici, A. Maggioni, N. Hacker, F. Landoni, S. Ackermann, and E. Campagnutta Systematic aortic and pelvic lymphadenectomy versus resection of bulky nodes only in optimally debulked advanced ovarian cancer: a randomized clinical trial J Natl Cancer Inst 97 8 2005 560 566 (Epub 2005/04/21) (Pubitemid 40723783)
5. H. Kitchener, A.M. Swart, Q. Qian, C. Amos, and M.K. Parmar Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study Lancet 373 9658 2009 125 136 (Epub 2008/12/17)
6. A. Mariani, M.J. Webb, G.L. Keeney, M.G. Haddock, G. Calori, and K.C. Podratz Low-risk corpus cancer: is lymphadenectomy or radiotherapy necessary? Am J Obstet Gynecol 182 6 2000 1506 1519 (Epub 2000/06/28) (Pubitemid 30437424)
7. J.N. Bakkum-Gamez, J. Gonzalez-Bosquet, N.N. Laack, A. Mariani, and S.C. Dowdy Current issues in the management of endometrial cancer Mayo Clin Proc 83 1 2008 97 112 (Epub 2008/01/05)
8. Center for Medicare and Medicaid Services Available from www.cms.gov
9. C.L. Creutzberg, R.A. Nout, M.L. Lybeert, C.C. Warlam-Rodenhuis, J.J. Jobsen, and J.W. Mens Fifteen-year radiotherapy outcomes of the randomized PORTEC-1 trial for endometrial carcinoma Int J Radiat Oncol Biol Phys 81 4 2011 e631 e638 (Epub 2011/06/07)
10. D.E. Cohn, W.K. Huh, J.M. Fowler, and J.M. Straughn Jr. Cost-effectiveness analysis of strategies for the surgical management of grade 1 endometrial adenocarcinoma Obstet Gynecol 109 6 2007 1388 1395 (Epub 2007/06/02) (Pubitemid 46869879)
11. H.M. Keys, J.A. Roberts, V.L. Brunetto, R.J. Zaino, N.M. Spirtos, and J.D. Bloss A phase III trial of surgery with or without adjunctive external pelvic radiation therapy in intermediate risk endometrial adenocarcinoma: a Gynecologic Oncology Group study Gynecol Oncol 92 3 2004 744 751 (Epub 2004/02/27) (Pubitemid 38251372)
12. R.R. Barakat Principles and practice of gynecologic oncology 2009 Lippincott, Williams & Wilkins Philadelphia, PA
13. J.N. Barlin, I. Puri, and R.E. Bristow Cytoreductive surgery for advanced or recurrent endometrial cancer: a meta-analysis Gynecol Oncol 118 1 2010 14 18 Epub 2010/05/04
14. H.D. Homesley, V. Filiaci, S.K. Gibbons, H.J. Long, D. Cella, and N.M. Spirtos A randomized phase III trial in advanced endometrial carcinoma of surgery and volume directed radiation followed by cisplatin and doxorubicin with or without paclitaxel: a Gynecologic Oncology Group study Gynecol Oncol 112 3 2009 543 552 (Epub 2008/12/26)
15. M.E. Randall, V.L. Filiaci, H. Muss, N.M. Spirtos, R.S. Mannel, and J. Fowler Randomized phase III trial of whole-abdominal irradiation versus doxorubicin and cisplatin chemotherapy in advanced endometrial carcinoma: a Gynecologic Oncology Group Study J Clin Oncol 24 1 2006 36 44 (Epub 2005/12/07) (Pubitemid 46630491)
16. A.N. Fader, D. Boruta, A.B. Olawaiye, and P.A. Gehrig Uterine papillary serous carcinoma: epidemiology, pathogenesis and management Curr Opin Obstet Gynecol 22 1 2010 21 29 (Epub 2009/12/03)
17. B.M. Sood, J. Jones, S. Gupta, D. Khabele, C. Guha, and C. Runowicz Patterns of failure after the multimodality treatment of uterine papillary serous carcinoma Int J Radiat Oncol Biol Phys 57 1 2003 208 216 (Epub 2003/08/12) (Pubitemid 36959758)
18. R.A. Nout, V.T. Smit, H. Putter, I.M. Jurgenliemk-Schulz, J.J. Jobsen, and L.C. Lutgens Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial Lancet 375 9717 2010 816 823 (Epub 2010/03/09)
19. N.S. Horowitz, W.A. Peters III, M.R. Smith, and C.W. Drescher Adjuvant high dose rate vaginal brachytherapy as treatment of stage I and II endometrial carcinoma Obstet Gynecol 99 2 2002 235 240 (Epub 2002/01/30) (Pubitemid 34113995)
20. Operating room charges Available from http://www.akrongeneral.org/portal/ page/portal/AGMC-PAGEGROUP/Price-guide/PRICE-GUIDE5
21. D.E. Cohn, K.H. Kim, K.E. Resnick, D.M. O'Malley, and J.M. Straughn Jr. At what cost does a potential survival advantage of bevacizumab make sense for the primary treatment of ovarian cancer? A cost-effectiveness analysis J Clin Oncol 29 10 2011 1247 1251 (Epub 2011/03/09)
22. I. Cleemput, M. Neyt, N. Thiry, C. De Laet, and M. Leys Using threshold values for cost per quality-adjusted life-year gained in healthcare decisions Int J Technol Assess Health Care 27 1 2011 71 76 (Epub 2011/01/26)
23. P.J. Neumann, E.A. Sandberg, C.M. Bell, P.W. Stone, and R.H. Chapman Are pharmaceuticals cost-effective? A review of the evidence Health Aff (Millwood) 19 2 2000 92 109 (Epub 2000/03/16)
24. Y.C. Shih, Y. Xu, J.N. Cormier, S. Giordano, S.H. Ridner, and T.A. Buchholz Incidence, treatment costs, and complications of lymphedema after breast cancer among women of working age: a 2-year follow-up study J Clin Oncol 27 12 2009 2007 2014 (Epub 2009/03/18)
25. N.R. Abu-Rustum, K. Alektiar, A. Iasonos, G. Lev, Y. Sonoda, and C. Aghajanian The incidence of symptomatic lower-extremity lymphedema following treatment of uterine corpus malignancies: a 12-year experience at Memorial Sloan-Kettering Cancer Center Gynecol Oncol 103 2 2006 714 718 (Epub 2006/06/03) (Pubitemid 44602163)
26. S. Kumar, S. Bandyopadhyay, A. Semaan, J.P. Shah, H. Mahdi, and R. Morris The role of frozen section in surgical staging of low risk endometrial cancer PLoS One 6 9 2011 e21912 (Epub 2011/09/14)
27. A.S. Case, R.P. Rocconi, J.M. Straughn Jr., M. Conner, L. Novak, and W. Wang A prospective blinded evaluation of the accuracy of frozen section for the surgical management of endometrial cancer Obstet Gynecol 108 6 2006 1375 1379 (Epub 2006/12/02) (Pubitemid 44901010)
28. P.A. Convery, L.A. Cantrell, N. Di Santo, G. Broadwater, S.C. Modesitt, and A.A. Secord Retrospective review of an intraoperative algorithm to predict lymph node metastasis in low-grade endometrial adenocarcinoma Gynecol Oncol 123 1 2011 65 70 (Epub 2011/07/12)
29. M.R. Milam, J. Java, J.L. Walker, D.S. Metzinger, L.P. Parker, and R.L. Coleman Nodal metastasis risk in endometrioid endometrial cancer Obstet Gynecol 119 2 Pt 1 2012 286 292 (Epub 2012/01/25)
30. A.L. Cheville, M. Almoza, J.N. Courmier, and J.R. Basford A prospective cohort study defining utilities using time trade-offs and the Euroqol-5D to assess the impact of cancer-related lymphedema Cancer 116 15 2010 3722 3731 (Epub 2010/06/22)