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Volumn 90, Issue 2, 2013, Pages 111-120

Response to pretransplant hypomethylating agents influences the outcome of allogeneic hematopoietic stem cell transplantation in adults with myelodysplastic syndromes

Author keywords

Hematopoietic stem cell transplantation; Hypomethylating agents; Myelodysplastic syndrome

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; DNA METHYLTRANSFERASE INHIBITOR; HYPOMETHYLATING AGENT; UNCLASSIFIED DRUG;

EID: 84872808089     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/ejh.12038     Document Type: Article
Times cited : (16)

References (43)
  • 1
    • 0022893790 scopus 로고
    • Myelodysplastic syndromes: natural history and features of prognostic importance
    • Mufti GJ, Galton DA. Myelodysplastic syndromes: natural history and features of prognostic importance. Clin Haematol 1986;15:953-71.
    • (1986) Clin Haematol , vol.15 , pp. 953-971
    • Mufti, G.J.1    Galton, D.A.2
  • 2
    • 78951487923 scopus 로고    scopus 로고
    • NCCN Clinical Practice Guidelines in Oncology: myelodysplastic syndromes
    • Greenberg PL, Attar E, Bennett JM, et al. NCCN Clinical Practice Guidelines in Oncology: myelodysplastic syndromes. J Natl Compr Canc Netw 2011;9:30-56.
    • (2011) J Natl Compr Canc Netw , vol.9 , pp. 30-56
    • Greenberg, P.L.1    Attar, E.2    Bennett, J.M.3
  • 3
    • 79952092841 scopus 로고    scopus 로고
    • Hypomethylating agents and other novel strategies in myelodysplastic syndromes
    • Garcia-Manero G, Fenaux P. Hypomethylating agents and other novel strategies in myelodysplastic syndromes. J Clin Oncol 2011;29:516-23.
    • (2011) J Clin Oncol , vol.29 , pp. 516-523
    • Garcia-Manero, G.1    Fenaux, P.2
  • 4
    • 62849104641 scopus 로고    scopus 로고
    • Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study
    • Fenaux P, Mufti GJ, Hellstrom-Lindberg E, et al. Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. Lancet Oncol 2009;10:223-32.
    • (2009) Lancet Oncol , vol.10 , pp. 223-232
    • Fenaux, P.1    Mufti, G.J.2    Hellstrom-Lindberg, E.3
  • 5
    • 33947281469 scopus 로고    scopus 로고
    • Survival advantage with decitabine versus intensive chemotherapy in patients with higher risk myelodysplastic syndrome: comparison with historical experience
    • Kantarjian HM, O'Brien S, Huang X, Garcia-Manero G, Ravandi F, Cortes J, Shan J, Davisson J, Bueso-Ramos CE, Issa JP. Survival advantage with decitabine versus intensive chemotherapy in patients with higher risk myelodysplastic syndrome: comparison with historical experience. Cancer 2007;109:1133-7.
    • (2007) Cancer , vol.109 , pp. 1133-1137
    • Kantarjian, H.M.1    O'Brien, S.2    Huang, X.3    Garcia-Manero, G.4    Ravandi, F.5    Cortes, J.6    Shan, J.7    Davisson, J.8    Bueso-Ramos, C.E.9    Issa, J.P.10
  • 6
    • 80051992418 scopus 로고    scopus 로고
    • Outcome of high-risk myelodysplastic syndrome after azacitidine treatment failure
    • Prebet T, Gore SD, Esterni B, et al. Outcome of high-risk myelodysplastic syndrome after azacitidine treatment failure. J Clin Oncol 2011;29:3322-7.
    • (2011) J Clin Oncol , vol.29 , pp. 3322-3327
    • Prebet, T.1    Gore, S.D.2    Esterni, B.3
  • 7
    • 77953057299 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation for myelodysplastic syndrome
    • Parmar S, de Lima M. Hematopoietic stem cell transplantation for myelodysplastic syndrome. Biol Blood Marrow Transplant 2010;16:S37-44.
    • (2010) Biol Blood Marrow Transplant , vol.16
    • Parmar, S.1    de Lima, M.2
  • 8
    • 58149196171 scopus 로고    scopus 로고
    • Allogeneic stem cell transplantation for adults with myelodysplastic syndromes: importance of pretransplant disease burden
    • Warlick ED, Cioc A, Defor T, Dolan M, Weisdorf D. Allogeneic stem cell transplantation for adults with myelodysplastic syndromes: importance of pretransplant disease burden. Biol Blood Marrow Transplant 2009;15:30-8.
    • (2009) Biol Blood Marrow Transplant , vol.15 , pp. 30-38
    • Warlick, E.D.1    Cioc, A.2    Defor, T.3    Dolan, M.4    Weisdorf, D.5
  • 9
    • 19044388157 scopus 로고    scopus 로고
    • Impact of disease burden at time of allogeneic stem cell transplantation in adults with acute myeloid leukemia and myelodysplastic syndromes
    • Kebriaei P, Kline J, Stock W, Kasza K, Le Beau MM, Larson RA, Van Besien K. Impact of disease burden at time of allogeneic stem cell transplantation in adults with acute myeloid leukemia and myelodysplastic syndromes. Bone Marrow Transplant 2005;35:965-70.
    • (2005) Bone Marrow Transplant , vol.35 , pp. 965-970
    • Kebriaei, P.1    Kline, J.2    Stock, W.3    Kasza, K.4    Le Beau, M.M.5    Larson, R.A.6    Van Besien, K.7
  • 10
    • 0025073138 scopus 로고
    • Allogeneic bone marrow transplantation for secondary leukaemia and myelodysplastic syndrome: a survey by the Leukaemia Working Party of the European Bone Marrow Transplantation Group (EBMTG)
    • De Witte Y, Zwaan G, Hermans J, et al. Allogeneic bone marrow transplantation for secondary leukaemia and myelodysplastic syndrome: a survey by the Leukaemia Working Party of the European Bone Marrow Transplantation Group (EBMTG). Br J Haematol 1990;74:151-5.
    • (1990) Br J Haematol , vol.74 , pp. 151-155
    • De Witte, Y.1    Zwaan, G.2    Hermans, J.3
  • 11
    • 27244435820 scopus 로고    scopus 로고
    • Comparison of 2 preparative regimens for stem cell transplantation from HLA-matched sibling donors in patients with advanced myelodysplastic syndrome
    • Kim YJ, Kim DW, Lee S, et al. Comparison of 2 preparative regimens for stem cell transplantation from HLA-matched sibling donors in patients with advanced myelodysplastic syndrome. Int J Hematol 2005;82:66-71.
    • (2005) Int J Hematol , vol.82 , pp. 66-71
    • Kim, Y.J.1    Kim, D.W.2    Lee, S.3
  • 12
    • 8944243549 scopus 로고    scopus 로고
    • Factors influencing outcome in de novo myelodysplastic syndromes treated by allogeneic bone marrow transplantation: a long-term study of 71 patients Societe Francaise de Greffe de Moelle
    • Sutton L, Chastang C, Ribaud P, et al. Factors influencing outcome in de novo myelodysplastic syndromes treated by allogeneic bone marrow transplantation: a long-term study of 71 patients Societe Francaise de Greffe de Moelle. Blood 1996;88:358-65.
    • (1996) Blood , vol.88 , pp. 358-365
    • Sutton, L.1    Chastang, C.2    Ribaud, P.3
  • 13
    • 0033920696 scopus 로고    scopus 로고
    • Analysis of prognostic factors for allogeneic marrow transplantation following busulfan and cyclophosphamide in myelodysplastic syndrome and after leukemic transformation
    • Copelan EA, Penza SL, Elder PJ, Ezzone SA, Scholl MD, Bechtel TP, Belt PS, Avalos BR. Analysis of prognostic factors for allogeneic marrow transplantation following busulfan and cyclophosphamide in myelodysplastic syndrome and after leukemic transformation. Bone Marrow Transplant 2000;25:1219-22.
    • (2000) Bone Marrow Transplant , vol.25 , pp. 1219-1222
    • Copelan, E.A.1    Penza, S.L.2    Elder, P.J.3    Ezzone, S.A.4    Scholl, M.D.5    Bechtel, T.P.6    Belt, P.S.7    Avalos, B.R.8
  • 14
    • 0028861053 scopus 로고
    • Intensive chemotherapy for poor prognosis myelodysplasia (MDS) and secondary acute myeloid leukemia (sAML) following MDS of more than 6 months duration. A pilot study by the Leukemia Cooperative Group of the European Organisation for Research and Treatment in Cancer (EORTC-LCG)
    • De Witte T, Suciu S, Peetermans M, Fenaux P, Strijckmans P, Hayat M, Jaksic B, Selleslag D, Zittoun R, Dardenne M. Intensive chemotherapy for poor prognosis myelodysplasia (MDS) and secondary acute myeloid leukemia (sAML) following MDS of more than 6 months duration. A pilot study by the Leukemia Cooperative Group of the European Organisation for Research and Treatment in Cancer (EORTC-LCG). Leukemia 1995;9:1805-11.
    • (1995) Leukemia , vol.9 , pp. 1805-1811
    • De Witte, T.1    Suciu, S.2    Peetermans, M.3    Fenaux, P.4    Strijckmans, P.5    Hayat, M.6    Jaksic, B.7    Selleslag, D.8    Zittoun, R.9    Dardenne, M.10
  • 15
    • 76149131707 scopus 로고    scopus 로고
    • Hypomethylating agent induction therapy followed by hematopoietic cell transplantation is feasible in patients with myelodysplastic syndromes
    • Cogle CR, Imanirad I, Wiggins LE, Hsu J, Brown R, Scornik JC, Wingard JR. Hypomethylating agent induction therapy followed by hematopoietic cell transplantation is feasible in patients with myelodysplastic syndromes. Clin Adv Hematol Oncol 2010;8:40-6.
    • (2010) Clin Adv Hematol Oncol , vol.8 , pp. 40-46
    • Cogle, C.R.1    Imanirad, I.2    Wiggins, L.E.3    Hsu, J.4    Brown, R.5    Scornik, J.C.6    Wingard, J.R.7
  • 16
    • 76749156659 scopus 로고    scopus 로고
    • 5-Azacitidine for myelodysplasia before allogeneic hematopoietic cell transplantation
    • Field T, Perkins J, Huang Y, et al. 5-Azacitidine for myelodysplasia before allogeneic hematopoietic cell transplantation. Bone Marrow Transplant 2010;45:255-60.
    • (2010) Bone Marrow Transplant , vol.45 , pp. 255-260
    • Field, T.1    Perkins, J.2    Huang, Y.3
  • 17
    • 70749131024 scopus 로고    scopus 로고
    • Non-intensive treatment with low-dose 5-aza-2′-deoxycytidine (DAC) prior to allogeneic blood SCT of older MDS/AML patients
    • Lubbert M, Bertz H, Ruter B, Marks R, Claus R, Wasch R, Finke J. Non-intensive treatment with low-dose 5-aza-2′-deoxycytidine (DAC) prior to allogeneic blood SCT of older MDS/AML patients. Bone Marrow Transplant 2009;44:585-8.
    • (2009) Bone Marrow Transplant , vol.44 , pp. 585-588
    • Lubbert, M.1    Bertz, H.2    Ruter, B.3    Marks, R.4    Claus, R.5    Wasch, R.6    Finke, J.7
  • 18
    • 67549109557 scopus 로고    scopus 로고
    • Feasibility of allo-SCT after hypomethylating therapy with decitabine for myelodysplastic syndrome
    • De Padua Silva L, de Lima M, Kantarjian H, et al. Feasibility of allo-SCT after hypomethylating therapy with decitabine for myelodysplastic syndrome. Bone Marrow Transplant 2009;43:839-43.
    • (2009) Bone Marrow Transplant , vol.43 , pp. 839-843
    • De Padua Silva, L.1    de Lima, M.2    Kantarjian, H.3
  • 19
    • 84858071500 scopus 로고    scopus 로고
    • Feasibility of hypomethylating agents followed by allogeneic hematopoietic cell transplantation in patients with myelodysplastic syndrome
    • Kim DY, Lee JH, Park YH, et al. Feasibility of hypomethylating agents followed by allogeneic hematopoietic cell transplantation in patients with myelodysplastic syndrome. Bone Marrow Transplant 2011;47:374-9.
    • (2011) Bone Marrow Transplant , vol.47 , pp. 374-379
    • Kim, D.Y.1    Lee, J.H.2    Park, Y.H.3
  • 20
    • 84864018433 scopus 로고    scopus 로고
    • Pretransplantation Therapy with Azacitidine vs Induction Chemotherapy and Posttransplantation Outcome in Patients with MDS
    • Gerds AT, Gooley TA, Estey EH, Appelbaum FR, Deeg HJ, Scott BL. Pretransplantation Therapy with Azacitidine vs Induction Chemotherapy and Posttransplantation Outcome in Patients with MDS. Biol Blood Marrow Transplant 2012;18:1211-8.
    • (2012) Biol Blood Marrow Transplant , vol.18 , pp. 1211-1218
    • Gerds, A.T.1    Gooley, T.A.2    Estey, E.H.3    Appelbaum, F.R.4    Deeg, H.J.5    Scott, B.L.6
  • 21
    • 70349256226 scopus 로고    scopus 로고
    • The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
    • Vardiman JW, Thiele J, Arber DA, et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood 2009;114:937-51.
    • (2009) Blood , vol.114 , pp. 937-951
    • Vardiman, J.W.1    Thiele, J.2    Arber, D.A.3
  • 22
    • 0030897009 scopus 로고    scopus 로고
    • International scoring system for evaluating prognosis in myelodysplastic syndromes
    • Greenberg P, Cox C, LeBeau MM, et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 1997;89:2079-88.
    • (1997) Blood , vol.89 , pp. 2079-2088
    • Greenberg, P.1    Cox, C.2    LeBeau, M.M.3
  • 23
    • 33745968917 scopus 로고    scopus 로고
    • Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia
    • Cheson BD, Greenberg PL, Bennett JM, et al. Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia. Blood 2006;108:419-25.
    • (2006) Blood , vol.108 , pp. 419-425
    • Cheson, B.D.1    Greenberg, P.L.2    Bennett, J.M.3
  • 24
    • 81255136909 scopus 로고    scopus 로고
    • Survival benefits from reduced intensity conditioning in allogeneic stem cell transplantation for young lower-risk MDS patients without significant co-morbidities
    • Lee SE, Kim YJ, Yahng SA, et al. Survival benefits from reduced intensity conditioning in allogeneic stem cell transplantation for young lower-risk MDS patients without significant co-morbidities. Eur J Haematol 2011;87:510-20.
    • (2011) Eur J Haematol , vol.87 , pp. 510-520
    • Lee, S.E.1    Kim, Y.J.2    Yahng, S.A.3
  • 25
    • 44649167561 scopus 로고    scopus 로고
    • Classification of HLA-matching for retrospective analysis of unrelated donor transplantation: revised definitions to predict survival
    • Weisdorf D, Spellman S, Haagenson M, et al. Classification of HLA-matching for retrospective analysis of unrelated donor transplantation: revised definitions to predict survival. Biol Blood Marrow Transplant 2008;14:748-58.
    • (2008) Biol Blood Marrow Transplant , vol.14 , pp. 748-758
    • Weisdorf, D.1    Spellman, S.2    Haagenson, M.3
  • 26
    • 18244407767 scopus 로고    scopus 로고
    • The effect of first-line imatinib interim therapy on the outcome of allogeneic stem cell transplantation in adults with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia
    • Lee S, Kim YJ, Min CK, Kim HJ, Eom KS, Kim DW, Lee JW, Min WS, Kim CC. The effect of first-line imatinib interim therapy on the outcome of allogeneic stem cell transplantation in adults with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood 2005;105:3449-57.
    • (2005) Blood , vol.105 , pp. 3449-3457
    • Lee, S.1    Kim, Y.J.2    Min, C.K.3    Kim, H.J.4    Eom, K.S.5    Kim, D.W.6    Lee, J.W.7    Min, W.S.8    Kim, C.C.9
  • 31
    • 50949133921 scopus 로고    scopus 로고
    • Della Porta MG, Bacigalupo A, WHO classification and WPSS predict posttransplantation outcome in patients with myelodysplastic syndrome: a study from the Gruppo Italiano Trapianto di Midollo Osseo (GITMO)
    • Alessandrino EP. Della Porta MG, Bacigalupo A, et al. WHO classification and WPSS predict posttransplantation outcome in patients with myelodysplastic syndrome: a study from the Gruppo Italiano Trapianto di Midollo Osseo (GITMO). Blood 2008;112:895-902.
    • (2008) Blood , vol.112 , pp. 895-902
    • Alessandrino, E.P.1
  • 32
    • 34948869819 scopus 로고    scopus 로고
    • Comorbidity and disease status based risk stratification of outcomes among patients with acute myeloid leukemia or myelodysplasia receiving allogeneic hematopoietic cell transplantation
    • Sorror ML, Sandmaier BM, Storer BE, Maris MB, Baron F, Maloney DG, Scott BL, Deeg HJ, Appelbaum FR, Storb R. Comorbidity and disease status based risk stratification of outcomes among patients with acute myeloid leukemia or myelodysplasia receiving allogeneic hematopoietic cell transplantation. J Clin Oncol 2007;25:4246-54.
    • (2007) J Clin Oncol , vol.25 , pp. 4246-4254
    • Sorror, M.L.1    Sandmaier, B.M.2    Storer, B.E.3    Maris, M.B.4    Baron, F.5    Maloney, D.G.6    Scott, B.L.7    Deeg, H.J.8    Appelbaum, F.R.9    Storb, R.10
  • 34
    • 80051718182 scopus 로고    scopus 로고
    • Mechanisms of resistance to decitabine in the myelodysplastic syndrome
    • Qin T, Castoro R, El Ahdab S, et al. Mechanisms of resistance to decitabine in the myelodysplastic syndrome. PLoS ONE 2011;6:e23372.
    • (2011) PLoS ONE , vol.6
    • Qin, T.1    Castoro, R.2    El Ahdab, S.3
  • 35
    • 77955900102 scopus 로고    scopus 로고
    • In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia
    • Choi J, Ritchey J, Prior JL, Holt M, Shannon WD, Deych E, Piwnica-Worms DR, DiPersio JF. In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia. Blood 2010;116:129-39.
    • (2010) Blood , vol.116 , pp. 129-139
    • Choi, J.1    Ritchey, J.2    Prior, J.L.3    Holt, M.4    Shannon, W.D.5    Deych, E.6    Piwnica-Worms, D.R.7    DiPersio, J.F.8
  • 36
    • 74949115148 scopus 로고    scopus 로고
    • Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting
    • Sanchez-Abarca LI, Gutierrez-Cosio S, Santamaria C, et al. Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting. Blood 2010;115:107-21.
    • (2010) Blood , vol.115 , pp. 107-121
    • Sanchez-Abarca, L.I.1    Gutierrez-Cosio, S.2    Santamaria, C.3
  • 37
    • 84859582203 scopus 로고    scopus 로고
    • Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia
    • Goodyear OC, Dennis M, Jilani NY, et al. Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia. Blood 2012;119:3361-9.
    • (2012) Blood , vol.119 , pp. 3361-3369
    • Goodyear, O.C.1    Dennis, M.2    Jilani, N.Y.3
  • 38
    • 78649601394 scopus 로고    scopus 로고
    • Maintenance therapy with low-dose azacitidine after allogeneic hematopoietic stem cell transplantation for recurrent acute myelogenous leukemia or myelodysplastic syndrome: a dose and schedule finding study
    • De Lima M, Giralt S, Thall PF, De Padua Silva L, Jones RB, Komanduri K, Braun TM, Nguyen HQ, Champlin R, Garcia-Manero G. Maintenance therapy with low-dose azacitidine after allogeneic hematopoietic stem cell transplantation for recurrent acute myelogenous leukemia or myelodysplastic syndrome: a dose and schedule finding study. Cancer 2010;116:5420-31.
    • (2010) Cancer , vol.116 , pp. 5420-5431
    • De Lima, M.1    Giralt, S.2    Thall, P.F.3    De Padua Silva, L.4    Jones, R.B.5    Komanduri, K.6    Braun, T.M.7    Nguyen, H.Q.8    Champlin, R.9    Garcia-Manero, G.10
  • 39
    • 77949425446 scopus 로고    scopus 로고
    • Potential role of adoptively transferred allogeneic WT1-specific CD4 +  and CD8 +  T lymphocytes for the sustained remission of refractory AML
    • Kim YJ, Cho SG, Lee S, et al. Potential role of adoptively transferred allogeneic WT1-specific CD4 +  and CD8 +  T lymphocytes for the sustained remission of refractory AML. Bone Marrow Transplant 2010;45:597-9.
    • (2010) Bone Marrow Transplant , vol.45 , pp. 597-599
    • Kim, Y.J.1    Cho, S.G.2    Lee, S.3
  • 41
    • 78650172030 scopus 로고    scopus 로고
    • Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine
    • Itzykson R, Thepot S, Quesnel B, et al. Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine. Blood 2011;117:403-11.
    • (2011) Blood , vol.117 , pp. 403-411
    • Itzykson, R.1    Thepot, S.2    Quesnel, B.3
  • 42
    • 70349753260 scopus 로고    scopus 로고
    • Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS
    • Follo MY, Finelli C, Mongiorgi S, et al. Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS. Proc Natl Acad Sci USA 2009;106:16811-6.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 16811-16816
    • Follo, M.Y.1    Finelli, C.2    Mongiorgi, S.3
  • 43
    • 84860781677 scopus 로고    scopus 로고
    • Safety, efficacy and biological predictors of response to sequential azacitidine and lenalidomide for elderly patients with acute myeloid leukemia
    • Pollyea DA, Kohrt HE, Gallegos L, et al. Safety, efficacy and biological predictors of response to sequential azacitidine and lenalidomide for elderly patients with acute myeloid leukemia. Leukemia 2012;26:893-901.
    • (2012) Leukemia , vol.26 , pp. 893-901
    • Pollyea, D.A.1    Kohrt, H.E.2    Gallegos, L.3


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