Synthetic hydrogel scaffold is an effective vehicle for delivery of INFUSE (rhBMP2) to critical-sized calvaria bone defects in rats

Journal of Orthopaedic Research

Volumn 31, Issue 3, 2013, Pages 401-406

  Mariner, Peter D ^a   Wudel, Justin M ^b   Miller, David E ^b   Genova, E Erin ^c   Streubel, Sven Olrik ^b   Anseth, Kristi S ^a,d  

^a UCB 450   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

absorbable collagen sponge (ACS); delivery vehicle; hydrogel; INFUSE bone graft; recombinant human bone morphogenic protein 2 (rhBMP2)

Indexed keywords

RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; TISSUE SCAFFOLD;

ANIMAL MODEL; ARTICLE; BIOCOMPATIBILITY; BONE GRAFT; BONE MASS; COMPUTER ASSISTED TOMOGRAPHY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENCAPSULATION; HYDROGEL; IMAGE PROCESSING; IMPLANT DELIVERY DEVICE; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; RAT; SKULL DEFECT; SKULL SURGERY;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; BONE TRANSPLANTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; FRACTURE HEALING; GELATIN SPONGE, ABSORBABLE; HUMANS; HYDROGEL; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SKULL; TISSUE SCAFFOLDS;

EID: 84872800198     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.22243     Document Type: Article

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