Overexpression of AQP5 in cervical cancer: Correlation with clinicopathological features and prognosis

Medical Oncology

Volumn 29, Issue 3, 2012, Pages 1998-2004

  Zhang, Ting ^a   Zhao, Chun ^a   Chen, Daozhen ^a   Zhou, Zuomin ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

AQP5; Cervical cancer; Ki 67; Prognosis

Indexed keywords

AQP5 PROTEIN; KI 67 ANTIGEN; MESSENGER RNA; PROTEIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CARCINOGENESIS; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; FOLLOW UP; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; OVERALL SURVIVAL; POSTMENOPAUSE; PREMENOPAUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR VOLUME; UTERINE CERVIX CANCER; WESTERN BLOTTING;

ADULT; AQUAPORIN 5; BLOTTING, WESTERN; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; NEOPLASM GRADING; NEOPLASM STAGING; PROGNOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION; UTERINE CERVICAL NEOPLASMS;

EID: 84872778597     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-011-0095-6     Document Type: Article

References (18)

1. Hu X, Schwarz JK, Lewis JS Jr, et al. A microRNA expression signature for cervical cancer prognosis. Cancer Res. 2010;70: 1441-8.
2. Behtash N, Mehrdad N. Cervical cancer: screening and prevention. Asian Pac J Cancer Prev. 2006;7:683-6.
3. Nico B, Ribatti D. Aquaporins in tumor growth and angiogenesis. Cancer Lett. 2010;294:135-8.
4. Verkman AS, Hara-Chikuma M, Papadopoulos MC. Aquaporins-new players in cancer biology. J Mol Med. 2008;86:523-9.
5. Moon C, Soria JC, Jang SJ, et al. Involvement of aquaporins in colorectal carcinogenesis. Oncogene. 2003;22:6699-703.
6. Yang JH, Shi YF, Cheng Q, et al. Expression and localization of aquaporin-5 in the epithelial ovarian tumors. Gynecol Oncol. 2006;100:294-9.
7. Zhang Z, Chen Z, Song Y, et al. Expression of aquaporin 5 increases proliferation and metastasis potential of lung cancer. J Pathol. 2010;221:210-20.
8. Chae YK, Woo J, Kim MJ, et al. Expression of aquaporin 5 (AQP5) promotes tumor invasion in human non small cell lung cancer. PLoS One. 2008;3:e2162.
9. Mann CD, Neal CP, Garcea G, et al. Prognostic molecular markers in hepatocellular carcinoma: a systematic review. Eur J Cancer. 2007;43:979-92.
10. Inagawa S, Itabashi M, Adachi S, et al. Expression and prognostic roles of beta-catenin in hepatocellular carcinoma: correlation with tumor progression and postoperative survival. Clin Cancer Res. 2002;8:450-6.
11. Ishibashi K, Hara S, Kondo S. Aquaporin water channels in mammals. Clin Exp Nephrol. 2009;13:107-17.
12. Saadoun S, Papadopoulos MC, Hara-Chikuma M, Verkman AS. Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption. Nature. 2005;434:786-92.
13. Hoque MO, Soria JC, Woo J, et al. Aquaporin 1 is overexpressed in lung cancer and stimulates NIH-3T3 cell proliferation and anchorage-independent growth. Am J Pathol. 2006;168:1345-53.
14. King LS, Agre P. Pathophysiology of the aquaporin water channels. Annu Rev Physiol. 1996;58:619-48.
15. Shen L, Zhu Z, Huang Y, et al. Expression profile of multiple aquaporins in human gastric carcinoma and its clinical significance. Biomed Pharmacother. 2010;64:313-8.
16. Kang SK, Chae YK, Woo J, et al. Role of human aquaporin 5 in colorectal carcinogenesis. Am J Pathol. 2008;173:518-25.
17. Watanabe T, Fujii T, Oya T, et al. Involvement of aquaporin-5 in differentiation of human gastric cancer cells. J Physiol Sci. 2009;59:113-22.
18. Woo J, Lee J, Chae YK, et al. Overexpression of AQP5, a putative oncogene, promotes cell growth and transformation. Cancer Lett. 2008;264:54-62.