Enzymatic activity of allergenic house dust and storage mite extracts

Journal of Medical Entomology

Volumn 50, Issue 1, 2013, Pages 147-154

  Morales, María ^a   Iraola, Víctor ^a   Leonor, Jose R ^a   Carnés, Jerónimo ^a  

^a Research and Development   (Spain)

Author keywords

Allergen extract; Allergen immunotherapy; Enzymatic activity; Mite

Indexed keywords

BIOLOGICAL PRODUCT; HOUSE DUST ALLERGEN; PEPTIDE HYDROLASE;

ACARIDAE; ANIMAL; ARTICLE; ENZYMOLOGY; IMMUNOLOGY; METABOLISM; PYROGLYPHIDAE;

ACARIDAE; ANIMALS; ANTIGENS, DERMATOPHAGOIDES; BIOLOGICAL AGENTS; PEPTIDE HYDROLASES; PYROGLYPHIDAE;

ACARI; ACARUS SIRO; BLOMIA TROPICALIS; CHORTOGLYPHUS ARCUATUS; DERMATOPHAGOIDES FARINAE; DERMATOPHAGOIDES PTERONYSSINUS; EUROGLYPHUS MAYNEI; GLYCYPHAGUS DOMESTICUS; LEPIDOGLYPHUS DESTRUCTOR; PYROGLYPHIDAE; TYROPHAGUS PUTRESCENTIAE;

EID: 84872730443     PISSN: 00222585     EISSN: None     Source Type: Journal    
DOI: 10.1603/ME12154     Document Type: Article

References (35)

1. Adam, E., K. K. Hansen, O. Astudillo Fernandez, L. Coulon, F. Bex, X. Duhant, E. Jaumotte, M. D. Hollenberg, and A. Jacquet. 2006. The house dust mite allergen Der p 1, unlike Der p 3, stimulates the expression of interleukin-8 inhumanairway epithelial cells via a proteinase-activated receptor-2-independent mechanism. J. Biol. Chem. 281: 6910-6923.
2. Asokananthan, N., P. T. Graham, J. Fink, D. A. Knight, A. J. Bakker, A. S. McWilliam, P. J. Thompson, and G. A. Stewart. 2002. Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells. J. Immunol. 168: 3577-3585.
3. Brown, A., K. Farmer, L. MacDonald, N. Kalsheker, D. Pritchard, C. Haslett, J. Lamb, and J. M. Sallenave. 2003. House dust mite Der p 1 downregulates defenses of the lung by inactivating elastase inhibitors. Am. J. Respir. Cell Mol. Biol. 29: 381-389.
4. Carnés, J., M. Boquete, F. J. Carballada, V. Iraola, M. T. Gallego, and E. Fernandez-Caldas. 2008. Enzymatic activity in body and fecal extracts of the storage mite Chortoglyphus arcuatus. Int. Arch Allergy Immunol. 145: 207-212.
5. Comoy, E. E., J. Pestel, C. Duez, G. A. Stewart, C. Vendeville, C. Fournier, F. Finkelman, A. Capron, and G. Thyphronitis. 1998. The house dust mite allergen, Dermatophagoides pteronyssinus, promotes type 2 responses by modulating the balance between IL-4 and IFN-gamma. J. Immunol. 160: 2456-2462.
6. Chavira, R., T. Burnett, and J. Hageman. 1984. Assaying proteinases with azocoll. Anal. Biochem. 136: 446-450.
7. Deb, R., F. Shakib, K. Reid, and H. Clark. 2007. Major house dust mite allergens Dermatophagoides pteronyssinus 1 and Dermatophagoides farinae 1 degrade and inactivate lung surfactant proteins A and D. J. Biol. Chem. 282: 36808-36819.
8. Elias, J. A., R. J. Homer, Q. Hamid, and C. G. Lee. 2005. Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma. J. Allerg. Clin. Immunol. 116: 497-500.
9. Fernandez-Caldas, E., M. Gallego, J. Carnés, and V. Iraola. 2008. Enzymatic activity of Dermatophagoides pteronyssinus extracts after acidic treatment. Int. Arch. Allegy Immunol. 145: 298-304.
10. Furmonaviciene, R., A. M. Ghaemmaghami, S. E. Boyd, N. S. Jones, K. Bailey, A. C. Willis, H. F. Sewell, D. A. Mitchell, and F. Shakib. 2007. The protease allergen Der p 1 cleaves cell surface DC-SIGN and DC-SIGNR: experimental analysis of in silico substrate identification and implications in allergic responses. Clin. Exp. Allergy 37: 231-242.
11. Gallego, M. T., V. Iraola, M. Himly, D. S. Robinson, C. Badiola, J. C. Garcia-Robaina, P. Briza, and J. Carnes. 2010. Depigmented and polymerised house dust mite allergoid: allergen content, induction of IgG4 and clinical response. Int. Arch. Allegy Immunol. 153: 61-69.
12. Ghaemmaghami, A. M., L. Gough, H. F. Sewell, and F. Shakib. 2002. The proteolytic activity of the major dust mite allergen Der p 1 conditions dendritic cells to produce less interleukin-12: allergen-induced Th2 bias determined at the dendritic cell level. Clin. Exp. Allergy 32: 1468-1475.
13. Gough, L., O. Schulz, H. F. Sewell, and F. Shakib. 1999. The cysteine protease activity of the major dust mite allergen Der p 1 selectively enhances the immunoglobulin E antibody response. J. Exp. Med. 190: 1897-1902.
14. Gunawan, H., T. Takai, S. Ikeda, K. Okumura, and H. Ogawa. 2008. Protease activity of allergenic pollen of cedar, cypress, juniper, birch and ragweed. Allergol. Int. 57: 83-91.
15. Herbert, C. A., C. M. King, P. C. Ring, S. T. Holgate, G. A. Stewart, P. J. Thompson, and C. Robinson. 1995. Augmentation of permeability in the bronchial epithelium by the house dust mite allergen Der p1. Am. J. Respir. Cell Mol. Biol. 12: 369-378.
16. Hubert, J., I. Køížková Kudlí ková, and V. Stejskal. 2004. Review of digestive enzymes of stored product and house dust mites. Phytophaga 14: 695-710.
17. Iraola, V., and E. Fernández-Caldas. 2009. Mapa acarológico de España. Elsevier España, Barcelona, Spain.
18. Kheradmand, F., A. Kiss, J. Xu, S. H. Lee, P. E. Kolattukudy, and D. B. Corry. 2002. A protease-activated pathway underlying Th cell type 2 activation and allergic lung disease. J. Immunol. 169: 5904-5911.
19. Kikuchi, Y., T. Takai, T. Kuhara, M. Ota, T. Kato, H. Hatanaka, S. Ichikawa, T. Tokura, H. Akiba, K. Mitsuishi, S. Ikeda, K. Okumura, and H. Ogawa. 2006. Crucial commitment of proteolytic activity of a purified recombinant major house dust mite allergen Der p1 to sensitization toward IgE and IgG responses. J. Immunol. 177: 1609-1617.
20. King, C., R. J. Simpson, R. L. Moritz, G. E. Reed, P. J. Thompson, and G. A. Stewart. 1996. The isolation and characterization of a novel collagenolytic serine protease allergen (Der p 9) from the dust mite Dermatophagoides pteronyssinus. J. Allergy Clin. Immunol. 98: 739-747.
21. Maruo, K., T. Akaike, T. Ono, T. Okamoto, and H. Maeda. 1997. Generation of anaphylatoxins through proteolytic processing of C3 and C5 by house dust mite protease. J. Allergy Clin. Immunol. 100: 253-260.
22. Morgan, M. S., and L. G. Arlian. 2006. Enzymatic activity in extracts of allergy-causing astigmatid mites. J. Med. Entomol. 43: 1200-1207.
23. Nisbet, A. J., and B. P. Billingsley. 2000. A comparative survey of the hydrolytic enzymes of ectoparasitic and freeliving mites. Int. J. Parasitol. 20: 19-27.
24. Page, K., V. S. Strunk, and M. B. Hershenson. 2003. Cockroach proteases increase IL-8 expression in human bronchial epithelial cells via activation of protease-activated receptor (PAR)-2 and extracellular-signal-regulated kinase. J. Allergy Clin. Immunol. 112: 1112-1118.
25. Polosa, R. 1993. Role of the kinin-kallikrein pathway in allergic diseases. Allergy 48: 217-225.
26. Runswick, S. M., T. Mitchell, P. Davies, C. Robinson, and D. R. Garrod. 2007. Pollen proteolytic enzymes degrade tight junctions. Respirology 12: 834-842.
27. Sanchez-Ramos, I., C. A. Hernandez, P. Castanera, and F. Ortego. 2004. Proteolytic activities in body and faecal extracts of the storage mite, Acarus farris. Med. Vet. Entomol. 18: 378-386.
28. Sarfati, M., and G. Delespesse. 1988. Possible role of human lymphocyte receptor for IgE (CD23) or its soluble fragments in the in vitro synthesis of human IgE. J. Immunol. 141: 2195-2199.
29. Schulz, O., H. F. Sewell, and F. Shakib. 1998. Proteolytic cleavage of CD25, the alpha subunit of the human T cell interleukin 2 receptor, by Der p 1, a major mite allergen with cysteine protease activity. J. Exp. Med. 187: 271-275.
30. Schulz, O., P. Laing, H. F. Sewell, and F. Shakib. 1995. Der p I, a major allergen of the house dust mite, proteolytically cleaves the low-affinity receptor for human IgE (CD23). Eur. J. Immunol. 25: 3191-3194.
31. Stewart, G. A. 1995. Dust mite allergens. Clin. Rev. Allergy Immunol. 13: 135-150.
32. Sun, G., M. A. Stacey, M. Schmidt, L. Mori, and S. Mattoli. 2001. Interaction of mite allergens Der p3 and Der p9 with protease-activated receptor-2 expressed by lung epithelial cells. J. Immunol. 167: 1014-1021.
33. Takahashi, K., T. Aoki, S. Kohmoto, H. Nishimura, Y. Kodera, A. Matsushima, and Y. Inada. 1990. Activation of kallikrein-kinin system in human plasma with purified serine protease from Dermatophagoides farinae. Int. Arch Allergy Appl. Immunol. 91: 80-85.
34. Tovey, E. R., M. D. Chapman, and T. A. Platts-Mills. 1981. Mite faeces are a major source of house dust allergens. Nature 289: 592-593.
35. Vinhas, R., L. Cortes, I. Cardoso, V. M. Mendes, B. Manadas, A. Todo-Bom, E. Pires, and P. Verissimo. 2011. Pollen proteases compromise the airway epithelial barrier through degradation of transmembrane adhesion proteins and lung bioactive peptides. Allergy 66: 1088-1098.