Obtusilactone B from Machilus thunbergii targets barrier-to-autointegration factor to treat cancer

Molecular Pharmacology

Volumn 83, Issue 2, 2013, Pages 367-376

  Kim, Wanil ^a   Lyu, Ha Na ^a   Kwon, Hyun Sook ^a   Kim, Ye Seul ^a   Lee, Kyung Ha ^a   Kim, Do Yeon ^a   Chakraborty, Goutam ^b   Choi, Kwan Yong ^a   Yoon, Ho Sup ^b   Kim, Kyong Tai ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; BARRIER TO AUTOINTEGRATION FACTOR; BUTYROLACTONE; OBTUSILACTONE B; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG; VACCINIA RELATED KINASE 1;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL NUCLEUS MEMBRANE; COMPUTER MODEL; CONTROLLED STUDY; DISSOCIATION; DRUG DETERMINATION; DRUG PROTEIN BINDING; ENZYME INHIBITION; IN VITRO STUDY; MACHILUS THUNBERGII; MEDICINAL PLANT; MITOSIS INHIBITION; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TARGET CELL DESTRUCTION; TUMOR CELL DESTRUCTION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL CYCLE; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; DNA; DNA-BINDING PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NEOPLASMS; NUCLEAR ENVELOPE; NUCLEAR PROTEINS; PHOSPHORYLATION; PLANT EXTRACTS; PLANT STEMS; PROTEIN-SERINE-THREONINE KINASES;

EID: 84872712508     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.112.082578     Document Type: Article

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