Identification of two novel human putative serine/threonine kinases, VRK1 and VRK2, with structural similarity to vaccinia virus B1R kinase

Genomics

Volumn 45, Issue 2, 1997, Pages 327-331

  Nezu, Jun Ichi ^a   Oku, Asuka ^a   Jones, Michael H ^a   Shimane, Miyuki ^a  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN SERINE THREONINE KINASE;

ARTICLE; CELL PROLIFERATION; CHROMOSOME 14Q; CHROMOSOME 2P; CONTROLLED STUDY; FETUS; FETUS LIVER; GENE ISOLATION; GENE LOCATION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; VACCINIA VIRUS; VIRUS REPLICATION;

VACCINIA; VACCINIA VIRUS;

EID: 0030711601     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1997.4938     Document Type: Article

References (32)

1. Banham, A. H., Leader, D. P., and Smith, G. L. (1993). Phosphorylation of ribosomal proteins by the vaccinia virus B1R protein kinase. FEBS Lett. 321: 27-31.
2. Banham, A. H., and Smith, G. L. (1992). Vaccinia virus gene B1R encodes a 34-kDa serine/threonine protein kinase that localizes in cytoplasmic factories and is packaged into virions. Virology 191: 803-812.
3. Beaud, G., Beaud, R., and Leader, D. P. (1995). Vaccinia virus gene H5R encodes a protein that is phosphorylated by the multisubstrate vaccinia virus B1R protein kinase. J. Virol. 69: 1819-1826.
4. Beaud, G., Sharif, A., Topa-Masse, A., and Leader, D. P. (1994). Ribosomal protein S2/Sa kinase purified from HeLa cells infected with vaccinia virus corresponds to the B1R protein kinase and phosphorylates in vitro the viral ssDNA-binding protein. J. Gen. Virol. 75: 283-293.
5. Bell, S. P., and Stillman, B. (1992). Nucleotide dependent recognition of chromosomal origins of DNA replication by multiprotein complex. Nature 357: 128-134.
6. Botchan, M. (1996). Coordinating DNA replication with cell division: Current status of the licensing concept. Proc. Natl. Acad. Sci. USA 93: 9997-10000.
7. Chellappan, S. P., Hiebert, M., Mudryj, M., Horowitz, J. M., and Nevins, J. R. (1991). The E2F transcription factor is a cellular target for the RB protein. Cell 65: 1053-1061.
8. Chenchik, A., Moqadam, F., and Siebert, P. (1995). Marathon cDNA amplification: A new method for cloning full-length cDNAs. CLONTECHniques X(1): 5-8.
9. Condit, R. C., Motyczka, A., and Spizz, G. (1983). Isolation, characterization, and physical mapping of temperature-sensitive mutants of vaccinia virus. Virology 128: 429-443.
10. Condit, R. C., and Motyczka, A. (1981). Isolation and preliminary characterization of temperature-sensitive mutants of vaccinia virus. Virology 113: 224-241.
11. Diatchenko, L., Lau, Y. C., Campbell, A. P., Chenchik, A., Moqadam, F., Huang, B., Lukyanov, S., Lukyanov, K., Gurskaya, N., Sverdlov, E. D., and Siebert, P. D. (1996). Suppression subtractive hybridization: A method for generating differentially regulated or tissue-specific cDNA probes and libraries. Proc. Natl. Acad. Sci. USA 93: 6025-6030.
12. Diffley, J. F. X. (1996). Once and only once upon a time: Specifying and regulating origins of DNA replication in eukaryotic cells. Genes Dev. 10: 2819-2830.
13. Hanks, S. K., and Hunter, T. (1995). Protein kinases 6. The eukaryotic protein kinase superfamily: Kinase (catalytic) domain structure and classification. FASEB J. 9: 576-596.
14. Hanks, S. K., Quinn, A. M., and Hunter, T. (1988). The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains. Science 241: 42-52.
15. Howard, S. T., and Smith, G. L. (1989). Two early vaccinia virus genes encode polypeptides related to protein kinases. J. Gen. Virol. 70: 3187-3201.
16. Huyhn, A., Dommergues, M., Izac, B., Croisille, L., Katz, A., Vainchenker, W., and Coulombel, L. (1995). Characterization of hematopoietic progenitors from human yolk sacs and embryos. Blood 86: 4474-4485.
17. Knighton, D. R., Zheng, J. H., Ten Eyck, L. F., Ashford, V. A., Xuong, N. H., Taylor, S. S., and Sowadski, J. M. (1991). Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science 253: 407-414.
18. Lin, S., Chen, W., and Broyles, S. S. (1992). The vaccinia virus B1R gene product is a serine/threonine protein kinase. J. Virol. 66: 2717-2723.
19. Moss, B. (1996). The viruses and their replication. In "Poxviridae" B. N. Fields, D. M. Knipe, and P. M. Howley, Eds.), Vol. 2, pp. 2637-2671, Lippincott-Raven, Philadelphia.
20. Nasmyth, K. (1996). Viewpoint: Putting the cell cycle in order. Science 274: 1643-1645.
21. Rempel, R. E., Anderson, M. K., Evans, E., and Traktman, P. (1990). Temperature-sensitive vaccinia virus mutants identify a gene with an essential role in viral replication. J. Virol. 64: 574-583.
22. Rempel, R. E. and Traktman, P. (1992). Vaccinia virus B1 kinase: phenotypic analysis of temperature-sensitive mutants and enzymatic characterization of recombinant proteins. J. Virol. 66: 4413-4426.
23. Sherr, C. J. (1996). Cancer cell cycle. Science 274: 1672-1677.
24. Smith, G. L., Chan, Y. S., and Howard, S. T. (1991). Nucleotide sequence of 42 kbp of vaccinia virus strain WR from near the right inverted terminal repeat. J. Gen. Virol. 72: 1349-1376.
25. Stillman, B. (1996). Cell cycle control of DNA replication. Science 274: 1659-1664.
26. Su, L., Hershberger, R. J., and Weissman, I. L. (1993). LYAR, a novel nucleolar protein with zinc finger DNA-binding motifs, is involved in cell growth regulation. Genes Dev. 7: 735-748.
27. Tanaka, M., Sasaki, H., Kino, I., Sugimura, T., and Terada, M. (1992). Genes preferentially expressed in embryo stomach are predominantly expressed in gastric cancer. Cancer Res. 52: 3372-3377.
28. Taya, Y., Yasuda, H., Kamijo, M., Nakaya, K., Nakamura, Y., Ohba, Y., Nishimura, S. (1989). In vitro phosphorylation of the tumor suppressor gene RB protein by mitosis-specific histone H1 kinase. Biochem. Biophys. Res. Commun. 164: 580-586.
29. Traktman, P., Anderson, M. K., and Rempel, R. E. (1989). Vaccinia virus encodes an essential gene with strong homology to protein kinases. J. Biol. Chem. 264(36): 21458-21461.
30. Walter, M. A., Spillett, D. J., Thomas, P., Weissenbach, J., and Goodfellow, P. N. (1994). A method for constructing radiation hybrid maps of whole genomes. Nature Genet. 7: 22-28
31. Yan, H., Gibson, S., Tye, B. K. (1991). Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function. Genes Dev. 5: 944-957.
32. Yan, H., Merchant, A. M., and Tye, B. K. (1993). Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast. Genes Dev. 7: 2149-2160.