Invasive candidiasis in Pakistan: Clinical characteristics, species distribution and antifungal susceptibility

Journal of Medical Microbiology

Volumn 62, Issue PART 2, 2013, Pages 259-268

  Farooqi, Joveria Qais ^a   Jabeen, K ^a   Saeed, N ^a   Iqbal, N ^b   Malik, B ^a   Lockhart, S R ^b   Zafar, A ^a   Brandt, M E ^b   Hasan, R ^a  

^a Department of Pathology Microbiology   (Pakistan)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; ANTIFUNGAL AGENT; CASPOFUNGIN; ECHINOCANDIN; FLUCONAZOLE; ITRACONAZOLE;

ADULT; AGED; ANTIBIOTIC SENSITIVITY; ARTICLE; CANDIDA ALBICANS; CANDIDA GLABRATA; CANDIDA KRUSEI; CANDIDA PARAPSILOSIS; CANDIDA TROPICALIS; DEMOGRAPHY; DEVICES; FEMALE; FUNGUS ISOLATION; HEALTH CARE; HOSPITAL ADMISSION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFECTION CONTROL; INVASIVE CANDIDIASIS; MALE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PAKISTAN; PRIORITY JOURNAL; RISK FACTOR; SPECIES DISTRIBUTION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIFUNGAL AGENTS; CANDIDA; CANDIDIASIS, INVASIVE; CHILD; CHILD, PRESCHOOL; DRUG RESISTANCE, FUNGAL; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; PAKISTAN; YOUNG ADULT;

EID: 84872710238     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.048785-0     Document Type: Article

References (40)

1. Ariff, S., Saleem, A. F., Soofi, S. B. & Sajjad, R. (2011). Clinical spectrum and outcomes of neonatal candidiasis in a tertiary care hospital in Karachi, Pakistan. J Infect Dev Ctries 5, 216-223.
2. Bader, M. S., Lai, S. M., Kumar, V. & Hinthorn, D. (2004). Candidemia in patients with diabetes mellitus: epidemiology and predictors of mortality. Scand J Infect Dis 36, 860-864.
3. Basu, S., Chakraborty, D., Dey, S. K. & Das, S. (2011). Biological characteristics of nosocomial Candida tropicalis isolated from different clinical materials of critically ill patients at ICU. Int J Microbiol Res 2, 112-119.
4. Chai, Y. A., Wang, Y., Khoo, A. L., Chan, F. Y., Chow, C., Kumarasinghe, G., Singh, K. & Tambyah, P. A. (2007). Predominance of Candida tropicalis bloodstream infections in a Singapore teaching hospital. Med Mycol 45, 435-439.
5. CLSI (2008). Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts; 3rd edn. Approved Standard M27-A3. Wayne, PA: Clinical and Laboratory Standards Institute.
6. Colombo, A. L., Nucci, M., Park, B. J., Nouér, S. A., Arthington-Skaggs, B., da Matta, D. A., Warnock, D., Morgan, J. & Brazilian Network Candidemia Study (2006). Epidemiology of candidemia in Brazil: a nationwide sentinel surveillance of candidemia in eleven medical centers. J Clin Microbiol 44, 2816-2823.
7. Das, S., Brown, T. M., Kellar, K. L., Holloway, B. P. & Morrison, C. J. (2006). DNA probes for the rapid identification of medically important Candida species using a multianalyte profiling system. FEMS Immunol Med Microbiol 46, 244-250.
8. Deak, E., Etienne, K. A., Lockhart, S. R., Gade, L., Chiller, T. & Balajee, S. A. (2010). Utility of a Luminex-based assay for multiplexed, rapid species identification of Candida isolates from an ongoing candidemia surveillance. Can J Microbiol 56, 348-351.
9. Diaz, M. R. & Fell, J. W. (2004). High-throughput detection of pathogenic yeasts of the genus Trichosporon. J Clin Microbiol 42, 3696-3706.
10. Dimopoulos, G., Karabinis, A., Samonis, G. & Falagas, M. E. (2007). Candidemia in immunocompromised and immunocompetent critically ill patients: a prospective comparative study. Eur J Clin Microbiol Infect Dis 26, 377-384.
11. Erdem, I., Oguzoglu, N., Ozturk Engin, D., Ozgultekin, A., Inan, A. S., Ceran, N., Kaya, F., Genc, I. & Goktas, P. (2010). Incidence, etiology and risk factors associated with mortality of nosocomial candidemia in a tertiary care hospital in Istanbul, Turkey. Med Princ Pract 19, 463-467.
12. Falagas, M. E., Roussos, N. & Vardakas, K. Z. (2010). Relative frequency of albicans and the various non-albicans Candida spp among candidemia isolates from inpatients in various parts of the world: a systematic review. Int J Infect Dis 14, e954-e966.
13. Hassan, I., Powell, G., Sidhu, M., Hart, W. M. & Denning, D. W. (2009). Excess mortality, length of stay and cost attributable to candidaemia. J Infect 59, 360-365.
14. Horn, D. L., Neofytos, D., Anaissie, E. J., Fishman, J. A., Steinbach, W. J., Olyaei, A. J., Marr, K. A., Pfaller, M. A., Chang, C.-H. & Webster, K. M. (2009). Epidemiology and outcomes of candidemia in 2019 patients: data from the prospective antifungal therapy alliance registry. Clin Infect Dis 48, 1695-1703.
15. Kontoyiannis, D. P., Marr, K. A., Park, B. J., Alexander, B. D., Anaissie, E. J., Walsh, T. J., Ito, J., Andes, D. R., Baddley, J. W. & other authors (2010). Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001-2006: overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database. Clin Infect Dis 50, 1091-1100.
16. Kothari, A. & Sagar, V. (2009). Epidemiology of Candida bloodstream infections in a tertiary care institute in India. Indian J Med Microbiol 27, 171-172.
17. Kothavade, R. J., Kura, M. M., Valand, A. G. & Panthaki, M. H. (2010). Candida tropicalis: its prevalence, pathogenicity and increasing resistance to fluconazole. J Med Microbiol 59, 873-880.
18. Kusne, S., Tobin, D., Pasculle, A. W., Van Thiel, D. H., Ho, M. & Starzl, T. E. (1994). Candida carriage in the alimentary tract of liver transplant candidates. Transplantation 57, 398-402.
19. Lin, M. Y., Carmeli, Y., Zumsteg, J., Flores, E. L., Tolentino, J., Sreeramoju, P. & Weber, S. G. (2005). Prior antimicrobial therapy and risk for hospital-acquired Candida glabrata and Candida krusei fungemia: a case-case-control study. Antimicrob Agents Chemother 49, 4555-4560.
20. Liu, C.-Y., Liao, C.-H., Chen, Y.-C. & Chang, S.-C. (2010). Changing epidemiology of nosocomial bloodstream infections in 11 teaching hospitals in Taiwan between 1993 and 2006. J Microbiol Immunol Infect 43, 416-429.
21. Nucci, M. & Colombo, A. L. (2007). Candidemia due to Candida tropicalis: clinical, epidemiologic, and microbiologic characteristics of 188 episodes occurring in tertiary care hospitals. Diagn Microbiol Infect Dis 58, 77-82.
22. O'Grady, N. P., Alexander, M., Burns, L. A., Dellinger, E. P., Garland, J., Heard, S. O., Lipsett, P. A., Masur, H., Mermel, L. A. & other authors (2011). Guidelines for the prevention of intravascular catheter-related infections. Clin Infect Dis 52, e162-e193.
23. Odds, F. C., Hanson, M. F., Davidson, A. D., Jacobsen, M. D., Wright, P., Whyte, J. A., Gow, N. A. & Jones, B. L. (2007). One year prospective survey of Candida bloodstream infections in Scotland. J Med Microbiol 56, 1066-1075.
24. Ortega, M., Marco, F., Soriano, A., Almela, M., Martínez, J. A., López, J., Pitart, C. & Mensa, J. (2011). Candida species bloodstream infection: epidemiology and outcome in a single institution from 1991 to 2008. J Hosp Infect 77, 157-161.
25. Pappas, P. G., Alexander, B. D., Andes, D. R., Hadley, S., Kauffman, C. A., Freifeld, A., Anaissie, E. J., Brumble, L. M., Herwaldt, L. & other authors (2010). Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET). Clin Infect Dis 50, 1101-1111.
26. Pereira, G. H., Müller, P. R., Szeszs, M. W., Levin, A. S. & Melhem, M. S. (2010). Five-year evaluation of bloodstream yeast infections in a tertiary hospital: the predominance of non-C. albicans Candida species. Med Mycol 48, 839-842.
27. Pfaller, M. A. & Diekema, D. J. (2007). Epidemiology of invasive candidiasis: a persistent public health problem. Clin Microbiol Rev 20, 133-163.
28. Pfaller, M. A., Andes, D., Diekema, D. J., Espinel-Ingroff, A., Sheehan, D. & CLSI Subcommittee for Antifungal Susceptibility Testing (2010a). Wild-type MIC distributions, epidemiological cutoff values and species-specific clinical breakpoints for fluconazole and Candida: time for harmonization of CLSI and EUCAST broth microdilution methods. Drug Resist Updat 13, 180-195.
29. Pfaller, M. A., Castanheira, M., Messer, S. A., Moet, G. J. & Jones, R. N. (2010b). Variation in Candida spp. distribution and antifungal resistance rates among bloodstream infection isolates by patient age: report from the SENTRY Antimicrobial Surveillance Program (2008-2009). Diagn Microbiol Infect Dis 68, 278-283.
30. Pfaller, M. A., Andes, D., Arendrup, M. C., Diekema, D. J., Espinel-Ingroff, A., Alexander, B. D., Brown, S. D., Chaturvedi, V., Fowler, C. L. & other authors (2011a). Clinical breakpoints for voriconazole and Candida spp. revisited: review of microbiologic, molecular, pharmacodynamic, and clinical data as they pertain to the development of species-specific interpretive criteria. Diagn Microbiol Infect Dis 70, 330-343.
31. Pfaller, M. A., Castanheira, M., Diekema, D. J., Messer, S. A. & Jones, R. N. (2011b). Triazole and echinocandin MIC distributions with epidemiological cutoff values for differentiation of wild-type strains from non-wild-type strains of six uncommon species of Candida. J Clin Microbiol 49, 3800-3804.
32. Pfaller, M. A., Diekema, D. J., Andes, D., Arendrup, M. C., Brown, S. D., Lockhart, S. R., Motyl, M., Perlin, D. S. & CLSI Subcommittee for Antifungal Testing (2011c). Clinical breakpoints for the echinocandins and Candida revisited: integration of molecular, clinical, and microbiological data to arrive at species-specific interpretive criteria. Drug Resist Updat 14, 164-176.
33. Pfaller, M. A., Moet, G. J., Messer, S. A., Jones, R. N. & Castanheira, M. (2011d). Candida bloodstream infections: comparison of species distributions and antifungal resistance patterns in community-onset and nosocomial isolates in the SENTRY Antimicrobial Surveillance Program, 2008-2009. Antimicrob Agents Chemother 55, 561-566.
34. Pfaller, M. A., Espinel-Ingroff, A., Canton, E., Castanheira, M., Cuenca-Estrella, M., Diekema, D. J., Fothergill, A., Fuller, J., Ghannoum, M. & other authors (2012). Wild-type MIC distributions and epidemiological cutoff values for amphotericin B, flucytosine, and itraconazole and Candida spp. as determined by CLSI broth microdilution. J Clin Microbiol 50, 2040-2046.
35. Picazo, J. J., González-Romo, F. & Candel, F. J. (2008). Candidemia in the critically ill patient. Int J Antimicrob Agents 32 (Suppl. 2), S83-S85.
36. Tan, T. Y., Tan, A. L., Tee, N. W., Ng, L. S. & Chee, C. W. (2010). The increased role of non-albicans species in candidaemia: results from a 3-year surveillance study. Mycoses 53, 515-521.
37. Wang, Q. M., Li, J., Wang, S. A. & Bai, F. Y. (2008). Rapid differentiation of phenotypically similar yeast species by single-strand conformation polymorphism analysis of ribosomal DNA. Appl Environ Microbiol 74, 2604-2611.
38. Yap, H. Y., Kwok, K. M., Gomersall, C. D., Fung, S. C., Lam, T. C., Leung, P. N., Hui, M. & Joynt, G. M. (2009). Epidemiology and outcome of Candida bloodstream infection in an intensive care unit in Hong Kong. Hong Kong Med J 15, 255-261.
39. Zaoutis, T. (2010). Candidemia in children. Curr Med Res Opin 26, 1761-1768.
40. Zimbeck, A. J., Iqbal, N., Ahlquist, A. M., Farley, M. M., Harrison, L. H., Chiller, T. & Lockhart, S. R. (2010). FKS mutations and elevated echinocandin MIC values among Candida glabrata isolates from U.S. population-based surveillance. Antimicrob Agents Chemother 54, 5042-5047.