Serum immunoglobulin A/C3 ratio predicts progression of immunoglobulin A nephropathy

Nephrology

Volumn 18, Issue 2, 2013, Pages 125-131

  Zhang, Jun ^a   Wang, Cheng ^a   Tang, Ying ^a   Peng, Hui ^a   Ye, Zeng Chun ^a   Li, Cui Cui ^a   Lou, Tan Qi ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

immunoglobulin A nephropathy; renal survival; risk factors; serum immunoglobulin A C3 ratio

Indexed keywords

COMPLEMENT COMPONENT C3; IMMUNOGLOBULIN A;

ADULT; ARTICLE; CHINESE; CLINICAL EXAMINATION; COHORT ANALYSIS; COMPLEMENT BLOOD LEVEL; DISEASE COURSE; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; HISTOLOGY; HUMAN; HUMAN TISSUE; HYPERTENSION; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOGLOBULIN BLOOD LEVEL; KIDNEY FAILURE; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; PREDICTIVE VALUE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEINURIA; RISK FACTOR; SURVIVAL;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; BIOLOGICAL MARKERS; BIOPSY; CHI-SQUARE DISTRIBUTION; CHINA; COMPLEMENT C3; DISEASE PROGRESSION; FEMALE; GLOMERULAR FILTRATION RATE; GLOMERULONEPHRITIS, IGA; HUMANS; IMMUNOGLOBULIN A; KAPLAN-MEIER ESTIMATE; KIDNEY; KIDNEY FAILURE, CHRONIC; MALE; MULTIVARIATE ANALYSIS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; PROTEINURIA; RISK FACTORS; TIME FACTORS; YOUNG ADULT;

EID: 84872693794     PISSN: 13205358     EISSN: 14401797     Source Type: Journal    
DOI: 10.1111/nep.12010     Document Type: Article

References (33)

1. D'Amico G,. The commonest glomerulonephritis in the world: IgA nephropathy. Q. J. Med. 1987; 64: 709-727.
2. Li LS, Liu ZH,. Epidemiologic data of renal diseases from a single unit in China: Analysis based on 13 519 renal biopsies. Kidney Int. 2004; 66: 920-923.
3. Lai KN, Mac-Moune LF, Li PK, Chan KW, Au TC, Tong KL,. The clinicopathological characteristics of IgA nephropathy in Hong Kong. Pathology 1988; 20: 15-19.
4. D'Amico G,. Natural history of idiopathic IgA nephropathy and factors predictive of disease outcome. Semin. Nephrol. 2004; 24: 179-196.
5. Frimat L, Briancon S, Hestin D, et al. IgA nephropathy: Prognostic classification of end-stage renal failure. L'Association des Nephrologues de l'Est. Nephrol. Dial. Transplant. 1997; 12: 2569-2575.
6. Le W, Liang S, Hu Y, et al. Long-term renal survival and related risk factors in patients with IgA nephropathy: Results from a cohort of 1155 cases in a Chinese adult population. Nephrol. Dial. Transplant. 2012; 27: 1479-1485.
7. Radford MJ, Donadio JJ, Bergstralh EJ, Grande JP,. Predicting renal outcome in IgA nephropathy. J. Am. Soc. Nephrol. 1997; 8: 199-207.
8. Bonnet F, Deprele C, Sassolas A, et al. Excessive body weight as a new independent risk factor for clinical and pathological progression in primary IgA nephritis. Am. J. Kidney Dis. 2001; 37: 720-727.
9. Syrjanen J, Mustonen J, Pasternack A,. Hypertriglyceridaemia and hyperuricaemia are risk factors for progression of IgA nephropathy. Nephrol. Dial. Transplant. 2000; 15: 34-42.
10. Trascasa ML, Egido J, Sancho J, Hernando L,. IgA glomerulonephritis (Berger's disease): Evidence of high serum levels of polymeric IgA. Clin. Exp. Immunol. 1980; 42: 247-254.
11. Schena FP, Pastore A, Ludovico N, Sinico RA, Benuzzi S, Montinaro V,. Increased serum levels of IgA1-IgG immune complexes and anti-F(ab')2 antibodies in patients with primary IgA nephropathy. Clin. Exp. Immunol. 1989; 77: 15-20.
12. Moldoveanu Z, Wyatt RJ, Lee JY, et al. Patients with IgA nephropathy have increased serum galactose-deficient IgA1 levels. Kidney Int. 2007; 71: 1148-1154.
13. Lai KN, Lai FM, Chui SH, et al. Studies of lymphocyte subpopulations and immunoglobulin production in IgA nephropathy. Clin. Nephrol. 1987; 28: 281-287.
14. van den Wall BA, Daha MR, Haaijman JJ, Radl J, van der, Ark A, van, Es LA,. Elevated production of polymeric and monomeric IgA1 by the bone marrow in IgA nephropathy. Kidney Int. 1989; 35: 1400-1404.
15. Harper SJ, Allen AC, Layward L, Hattersley J, Veitch PS, Feehally J,. Increased immunoglobulin A and immunoglobulin A1 cells in bone marrow trephine biopsy specimens in immunoglobulin A nephropathy. Am. J. Kidney Dis. 1994; 24: 888-892.
16. Barratt J, Smith AC, Molyneux K, Feehally J,. Immunopathogenesis of IgAN. Semin. Immunopathol. 2007; 29: 427-443.
17. Tomino Y, Suzuki S, Imai H, et al. Measurement of serum IgA and C3 may predict the diagnosis of patients with IgA nephropathy prior to renal biopsy. J. Clin. Lab. Anal. 2000; 14: 220-223.
18. Nakayama K, Ohsawa I, Maeda-Ohtani A, Murakoshi M, Horikoshi S, Tomino Y,. Prediction of diagnosis of immunoglobulin A nephropathy prior to renal biopsy and correlation with urinary sediment findings and prognostic grading. J. Clin. Lab. Anal. 2008; 22: 114-118.
19. Komatsu H, Fujimoto S, Hara S, Sato Y, Yamada K, Eto T,. Relationship between serum IgA/C3 ratio and progression of IgA nephropathy. Intern. Med. 2004; 43: 1023-1028.
20. Ishiguro C, Yaguchi Y, Funabiki K, Horikoshi S, Shirato I, Serum TY,. IgA/C3 ratio may predict diagnosis and prognostic grading in patients with IgA nephropathy. Nephron 2002; 91: 755-758.
21. Maeda A, Gohda T, Funabiki K, Horikoshi S, Shirato I, Tomino Y,. Significance of serum IgA levels and serum IgA/C3 ratio in diagnostic analysis of patients with IgA nephropathy. J. Clin. Lab. Anal. 2003; 17: 73-76.
22. Shen P, He L, Jiang Y, Wang C, Chen M,. Useful indicators for performing renal biopsy in adult patients with isolated microscopic haematuria. Int. J. Clin. Pract. 2007; 61: 789-794.
23. Lee SM, Rao VM, Franklin WA, et al. IgA nephropathy: Morphologic predictors of progressive renal disease. Hum. Pathol. 1982; 13: 314-322.
24. Ma YC, Zuo L, Chen JH, et al. Improved GFR estimation by combined creatinine and cystatin C measurements. Kidney Int. 2007; 72: 1535-1542.
25. Berthoux F, Mohey H, Laurent B, Mariat C, Afiani A, Thibaudin L,. Predicting the risk for dialysis or death in IgA nephropathy. J. Am. Soc. Nephrol. 2011; 22: 752-761.
26. Descamps-Latscha B, Witko-Sarsat V, Nguyen-Khoa T, et al. Early prediction of IgA nephropathy progression: Proteinuria and AOPP are strong prognostic markers. Kidney Int. 2004; 66: 1606-1612.
27. Shi Y, Chen W, Jalal D, et al. Clinical outcome of hyperuricemia in IgA nephropathy: A retrospective cohort study and randomized controlled trial. Kidney Blood Press. Res. 2012; 35: 153-160.
28. Lv J, Zhang H, Zhou Y, Li G, Zou W, Wang H,. Natural history of immunoglobulin A nephropathy and predictive factors of prognosis: A long-term follow up of 204 cases in China. Nephrology (Carlton) 2008; 13: 242-246.
29. Berger J, Hinglais N,. [Intercapillary deposits of IgA-IgG]. J. Urol. Nephrol. (Paris) 1968; 74: 694-695.
30. Hiemstra PS, Biewenga J, Gorter A, et al. Activation of complement by human serum IgA, secretory IgA and IgA1 fragments. Mol. Immunol. 1988; 25: 527-533.
31. Roos A, Bouwman LH, van, Gijlswijk-Janssen DJ, Faber-Krol MC, Stahl GL, Daha MR,. Human IgA activates the complement system via the mannan-binding lectin pathway. J. Immunol. 2001; 167: 2861-2868.
32. Cattran DC, Coppo R, Cook HT, et al. The Oxford classification of IgA nephropathy: Rationale, clinicopathological correlations, and classification. Kidney Int. 2009; 76: 534-545.
33. Roberts IS, Cook HT, Troyanov S, et al. The Oxford classification of IgA nephropathy: Pathology definitions, correlations, and reproducibility. Kidney Int. 2009; 76: 546-556.