Nano-hydroxyapatite-coated PEEK implants: A pilot study in rabbit bone

Journal of Biomedical Materials Research - Part A

Volumn 101 A, Issue 2, 2013, Pages 465-471

  Barkarmo, Sargon ^a   Wennerberg, Ann ^a,b   Hoffman, Maria ^a   Kjellin, Per ^c   Breding, Karin ^c   Handa, Paul ^c   Stenport, Victoria ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b MALMÖ UNIVERSITY   (Sweden)

^c Promimic AB   (Sweden)

Author keywords

Hydroxyapatite; Nanotopography; Osseointegration; Peek; Polyetheretherketone

Indexed keywords

BONE AREA; BONE-TO-IMPLANT CONTACT; CA/P RATIO; COATED IMPLANTS; HEALING TIME; HISTOMORPHOMETRY; IMPLANT DESIGN; IMPLANT SURFACE; IN-VIVO; NANO-HA; NANOCRYSTALLINES; NANOTOPOGRAPHIES; NEW ZEALAND RABBITS; OPTICAL INTERFEROMETRY; OSSEOINTEGRATION; PILOT STUDIES; POLYMER SURFACES; SEM IMAGE; SURFACE-MODIFIED; THIN LAYERS; XPS ANALYSIS;

ATOMIC FORCE MICROSCOPY; CYLINDERS (SHAPES); ETHERS; HYDROXYAPATITE; IMPLANTS (SURGICAL); NANOCOMPOSITES; PHOTOELECTRONS; POLYETHER ETHER KETONES; SCANNING ELECTRON MICROSCOPY; TISSUE; X RAY PHOTOELECTRON SPECTROSCOPY;

BONE;

HYDROXYAPATITE; POLYETHERETHERKETONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATOMIC FORCE MICROSCOPY; BONE IMPLANT; BONE REGENERATION; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; CONTROLLED STUDY; EXPERIMENTAL RABBIT; FEMALE; FEMUR; FRACTURE HEALING; HISTOLOGY; IN VIVO STUDY; INTERFEROMETRY; MATERIAL COATING; NONHUMAN; PILOT STUDY; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; TISSUE STRUCTURE; X RAY PHOTOELECTRON SPECTROSCOPY;

ANIMALS; BONE AND BONES; COATED MATERIALS, BIOCOMPATIBLE; DURAPATITE; FEMALE; IMPLANTS, EXPERIMENTAL; KETONES; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; PHOTOELECTRON SPECTROSCOPY; PILOT PROJECTS; POLYETHYLENE GLYCOLS; RABBITS; SURFACE PROPERTIES;

EID: 84872680339     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.34358     Document Type: Article

References (29)

1. Williams DF, McNamara A, Turner RM Potential of polyetheretherketone (PEEK) and carbon-fibre-reinforced PEEK in medical applications. J Mater Sci Lett 1987; 6: 188-190.
2. Kurtz SM, Devine JN PEEK biomaterials in trauma, orthopedic, and spinal implants. Biomaterials 2007; 28: 4845-4869.
3. Harsha AP, Tewari US The effect of fibre reinforcement and solid lubricants on abrasive wear behavior of polyetheretherketone composites. J Reinf Plast Compos 2003; 22: 751-767.
4. Skinner HB. Composite technology for total hip arthroplasty. Clin Orthop Relat Res 1988: 224-236.
5. Toth JM, Wang M, Estes B.T., Scifert JL, Seim HB, III, Turner AS. Polyetheretherketone as a biomaterial for spinal applications. Biomaterials 2006; 27: 324-334.
6. Katzer A, Marquardt H, Westendorf J., Wening JV, von Foerster G. Polyetheretherketone - Cytotoxicity and mutagenicity in vitro. Biomaterials 2002; 23: 1749-1759.
7. Morrison C, Macnair R, MacDonald C., Wykman A, Goldie I, Grant MH In vitro biocompatibility testing of polymers for orthopaedic implants using cultured fibroblasts and osteoblasts. Biomaterials 1995; 16: 987-992.
8. Rivard CH, Rhalmi S, Coillard C. In vivo biocompatibility testing of peek polymer for a spinal implant system: A study in rabbits. J Biomed Mater Res 2002; 62: 488-498.
9. Abu Bakar M.S., Cheng MH, Tang S.M., Yu SC, Liao K, Tan CT, Khor K.A., Cheang P. Tensile properties, tension-tension fatigue and biological response of polyetheretherketone-hydroxyapatite composites for load-bearing orthopedic implants. Biomaterials 2003; 24: 2245-2250.
10. Ha SW, Mayer J, Koch B., Wintermantel E. Plasma-sprayed hydroxylapatite coating on carbon fibre reinforced thermoplastic composite materials. J Mater Sci: Mater Med 1994; 5: 481-484.
11. Tan KH, Chua CK, Leong K.F., Cheah CM, Cheang P, Abu Bakar MS, Cha SW Scaffold development using selective laser sintering of polyetheretherketone- hydroxyapatite biocomposite blends. Biomaterials 2003; 24: 3115-3123.
12. Boyan BD, Hummert TW, Dean D.D., Schwartz Z. Role of material surfaces in regulating bone and cartilage cell response. Biomaterials 1996; 17: 137-146.
13. Ha SW, Gisep A, Mayer J., Wintermantel E, Gruner H, Wieland M. Topographical characterization and microstructural interface analysis of vacuum-plasma-sprayed titanium and hydroxyapatite coatings on carbon fibre-reinforced poly(etheretherketone). J Mater Sci Mater Med 1997; 8: 891-896.
14. Gottlander M, Albrektsson T, Carlsson LV A histomorphometric study of unthreaded hydroxyapatite-coated and titanium-coated implants in rabbit bone. Int J Oral Maxillofac Implants 1992; 7: 485-490.
15. Soballe K, Overgaard S. The current status of hydroxyapatite coating of prostheses. J Bone Joint Surg Br 1996; 78: 689-691.
16. Zhu X, Eibl O, Scheideler L., Geis-Gerstorfer J. Characterization of nano hydroxyapatite/collagen surfaces and cellular behaviors. J Biomed Mater Res A 2006; 79: 114-127.
17. Meirelles L, Arvidsson A, Andersson M., Kjellin P, Albrektsson T, Wennerberg A. Nano hydroxyapatite structures influence early bone formation. J Biomed Mater Res A 2008; 87: 299-307.
18. Kjellin P, Andersson M. SE527610. 2004.
19. Wennerberg A, Albrektsson T. Suggested guidelines for the topographic evaluation of implant surfaces. Int J Oral Maxillofac Implants 2000; 15: 331-344.
20. Donath K. Die trenn-dünnschliff-technik zur herstellung histologischer präparate von nicht schneidbaren geweben und materialien. Der Präparator 1988; 34: 197-206.
21. Sakoh J, Wahlmann U, Stender E., Nat R, Al-Nawas B, Wagner W. Primary stability of a conical implant and a hybrid, cylindric screwtype implant in vitro. Int J Oral Maxillofac Implants 2006; 21: 560-566.
22. Ivanoff CJ, Sennerby L, Lekholm U. Influence of initial implant mobility on the integration of titanium implants. Clin Oral Implants Res 1996; 7: 120-127.
23. Schatzker J, Horne JG, Sumner-Smith G. The effect of movement on the holding power of screws in bone. Clin Orthop Relat Res 1975: 257-262.
24. Albrektsson T, Branemark PI, Hansson H.A., Lindstrom J. Osseointegrated titanium implants. Acta Orthop Scand 1981; 52: 155-170.
25. Albrektsson T, Wennerberg A. Oral implant surfaces: Part 1 - Review focusing on topographic and chemical properties of different surfaces and in vivo responses to them. Int J Prosthodont 2004; 17: 536-543.
26. Wennerberg A. On surface roughness and implant incorporation. PhD thesis. Göteborg, Sweden; 1996.
27. Jarcho M, Kay JF, Gumaer K.I., Doremus RH, Drobeck HP Tissue, cellular and subcellular events at a bone-ceramic hydroxylapatite interface. J Bioeng 1977; 1: 79-92.
28. Ducheyne P, Qiu Q. Bioactive ceramics: The effect of surface reactivity on bone formation and bone cell function. Biomaterials 1999; 20: 2287-2303.
29. Cook SD, Thomas KA, Dalton J.E., Volkman TK, Whitecloud TS, III, Kay JF. Hydroxylapatite coating of porous implants improves bone ingrowth and interface attachment strength. J Biomed Mater Res 1992; 26: 989-1001.