Houttuynia cordata thunb fraction induces human leukemic molt-4 cell apoptosis through the endoplasmic reticulum stress pathway

Asian Pacific Journal of Cancer Prevention

Volumn 13, Issue 5, 2012, Pages 1977-1981

  Prommaban, Adchara ^a   Kodchakorn, Kanchanok ^a   Kongtawelert, Prachya ^a   Banjerdpongchai, Ratana ^a  

^a Faculty of Medicine Chiang Mai University   (Thailand)

Author keywords

Apoptosis; Endoplasmic reticulum stress; Houttuynia cordata thunb; Human leukemic Molt 4 cells

Indexed keywords

BAX PROTEIN, HUMAN; CASPASE; DIABLO PROTEIN, HUMAN; HEAT SHOCK PROTEIN; HERBACEOUS AGENT; MITOCHONDRIAL PROTEIN; MOLECULAR CHAPERONE GRP78; PROTEIN BAX; SIGNAL PEPTIDE;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECT; ENDOPLASMIC RETICULUM STRESS; HOUTTUYNIA; HUMAN; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PATHOLOGY; T CELL LEUKEMIA; TUMOR CELL CULTURE; WESTERN BLOTTING;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CASPASES; CELL PROLIFERATION; DRUGS, CHINESE HERBAL; ENDOPLASMIC RETICULUM STRESS; HEAT-SHOCK PROTEINS; HOUTTUYNIA; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKEMIA, T-CELL; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; TUMOR CELLS, CULTURED;

EID: 84872678720     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2012.13.5.1977     Document Type: Article

References (16)

1. Banjerdpongchai R, Kongtawelert P (2011). Ethanolic extract of fermented Thunb induces human leukemic HL-60 and Molt-4 cell apoptosis via oxidative stress and a mitochondrial pathway. Asian Pac J Cancer Prev, 12, 2871-4.
2. Galluzzi L, Vitale I, Abrams JM, et al (2012). Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ, 19, 107-20.
3. Han EH, Park JH, Kim JY, Jeong HG (2009). Houttuynia cordata water extract suppresses anaphylactic reaction and IgE-mediated allergic response by inhibiting multiple steps of FcepsilonRI signaling in mast cells. Food Chem Toxicol, 47, 1659-66.
4. Hengartner MO (2000). The biochemistry of apoptosis. Nature, 407, 770-6.
5. Hussain SG, Ramaiah KVA (2007). Endoplasmic reticulum: Stress, signalling and apoptosis. Cur Sci, 93, 1684-96.
6. Kudo TKS, Hara H, Morimoto N, et al (2008). A molecular chaperone inducer protects neurons from ER stress. Cell Death Differ, 15, 364-75.
7. Kusirisin W, Srichairatanakool S, Lerttrakarnnon P, et al (2009). Antioxidative activity, polyphenolic content and anti-glycation effect of some Thai medicinal plants traditionally used in diabetic patients. Med Chem, 5, 139-47.
8. Lai KC, Chiu YJ, Tang YJ, et al (2010). Houttuynia cordata Thunb extract inhibits cell growth and induces apoptosis in human primary colorectal cancer cells. Anticancer Res, 30, 3549-56.
9. Li J, Xia X, Ke Y, et al (2007). Trichosanthin induced apoptosis in HL-60 cells via mitochondrial and endoplasmic reticulum stress signaling pathways. Biochim Biophys Acta, 1770, 1169-80.
10. Li W, Zhou P, Zhang Y, He L (2011). Houttuynia cordata, a novel and selective COX-2 inhibitor with anti-inflammatory activity. J Ethnopharmacol, 133, 922-7.
11. Pae HO, Jeong SO, Jeong GS, et al (2007). Curcumin induces pro-apoptotic endoplasmic reticulum stress in human leukemia HL-60 cells. Biochem Biophys Res Commun, 353, 1040-5.
12. Park H, Oh MS (2012). Houttuyniae Herba protects rat primary cortical cells from Aβ25-35-induced neurotoxicity via regulation of calcium influx and mitochondria-mediated apoptosis. Hum Exp Toxicol, 31, 698-709
13. Shiraishi H, Okamoto H, Yoshimura A, Yoshida H (2006) ER stress-induced apoptosis and caspase-12 activation occurs downstream of mitochondrial apoptosis involving Apaf-1. J Cell Sci, 119, 3958-66.
14. Su WC, Chang SL, Chen TY, Chen JS, Tsao CJ (2000). Comparison of in vitro growth-inhibitory activity of carboplatin and cisplatin on leukemic cells and hematopoietic progenitors: the myelosuppressive activity of carboplatin may be greater than its antileukemic effect. Jpn J Clin Oncol, 30, 562-7.
15. Tang YJ, Yang JS, Lin CF, et al (2009). Houttuynia cordata Thunb extract induces apoptosis through mitochondrial-dependent pathway in HT-29 human colon adenocarcinoma cells. Oncol Rep, 22, 1051-6.
16. Verfaillie T, Garg AD, Agostinis P (2010). Targeting ER stress induced apoptosis and inflammation in cancer. Cancer Lett, 298, 1-16.