Controlled treadmill exercise eliminates chondroid deposits and restores tensile properties in a new murine tendinopathy model

Journal of Biomechanics

Volumn 46, Issue 3, 2013, Pages 498-505

  Bell, Rebecca ^a   Li, Jun ^a   Gorski, Daniel J ^a   Bartels, Anne K ^a   Shewman, Elizabeth F ^a   Wysocki, Robert W ^a   Cole, Brian J ^a   Bach, Bernard R ^a   Mikecz, Katalin ^a   Sandy, John D ^a   Plaas, Anna H ^a   Wang, Vincent M ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Aggrecan; Collagen; Gene expression; Mechanical loading; Tendinopathy

Indexed keywords

ACHILLES TENDONS; AGGRECAN; BIOLOGICAL PATHWAYS; COLLAGEN FIBER; MATERIAL PROPERTY; MAXIMUM STRESS; MECHANICAL LOADING; NORMAL CONTROLS; TENDINOPATHY;

BIOMECHANICS; COLLAGEN; GENE EXPRESSION; LOADING; MAMMALS; SPORTING GOODS;

TENDONS;

COLLAGEN; COLLAGEN TYPE 1A1; COLLAGEN TYPE 2A1; COLLAGEN TYPE 3A1; MEMBRANE PROTEIN; PROTEIN ACAN; PROTEIN FN1; STROMELYSIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ACHILLES TENDINITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; CARTILAGE CELL; CHONDROPATHY; CONTROLLED STUDY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; KINESIOTHERAPY; LOCOMOTION; MALE; MECHANICAL STRESS; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STRESS STRAIN RELATIONSHIP; TENDON STRESS; TREADMILL EXERCISE; TREATMENT DURATION;

ANIMALS; DISEASE MODELS, ANIMAL; EXERCISE THERAPY; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION; HUMANS; MALE; MICE; TENDINOPATHY; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA1; WEIGHT-BEARING;

EID: 84872595617     PISSN: 00219290     EISSN: 18732380     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2012.10.020     Document Type: Article

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