-
1
-
-
23744473720
-
Aromatase inhibitors: Combinations with fulvestrant or signal transduction inhibitors as a strategy to overcome endocrine resistance
-
DOI 10.1016/j.jsbmb.2005.04.004, PII S0960076005001822
-
Johnston SR, Martin LA, Head J, et al: Aromatase inhibitors: Combinations with fulvestrant or signal transduction inhibitors as a strategy to overcome endocrine resistance. J Steroid Biochem Mol Biol 95:173-181, 2005 (Pubitemid 41137308)
-
(2005)
Journal of Steroid Biochemistry and Molecular Biology
, vol.95
, Issue.1-5
, pp. 173-181
-
-
Johnston, S.R.D.1
Martin, L.-A.2
Head, J.3
Smith, I.4
Dowsett, M.5
-
2
-
-
77950633401
-
New strategies in estrogen receptor-positive breast cancer
-
Johnston SRD: New strategies in estrogen receptor-positive breast cancer. Clinical Cancer Res 16:1979-1987, 2010
-
(2010)
Clinical Cancer Res
, vol.16
, pp. 1979-1987
-
-
Srd, J.1
-
3
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
Network CGA: Comprehensive molecular portraits of human breast tumours. Nature 490:61-70, 2012
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
Cga, N.1
-
4
-
-
0036633164
-
Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells
-
Clark AS, West K, Streicher S, et al: Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells. Mol Cancer Ther 1:707-717, 2002
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 707-717
-
-
Clark, A.S.1
West, K.2
Streicher, S.3
-
5
-
-
84872517569
-
Resistance to endocrine therapy in estrogen receptor-positive (ER+) breast cancer is dependent upon phosphatidylinositol-3 kinase (PI3K) signaling
-
Miller T, Fox E, Gonzalez-Angulo A, et al: Resistance to endocrine therapy in estrogen receptor-positive (ER+) breast cancer is dependent upon phosphatidylinositol-3 kinase (PI3K) signaling. Cancer Res 69:24, 2009 (suppl)
-
(2009)
Cancer Res
, vol.69
, Issue.SUPPL.
, pp. 24
-
-
Miller, T.1
Fox, E.2
Gonzalez-Angulo, A.3
-
6
-
-
6944235337
-
Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt activity
-
DOI 10.1158/1078-0432.CCR-04-0035
-
deGraffenried LA, Friedrichs WE, Russell DH, et al: Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity. Clin Cancer Res 10:8059-8067, 2004 (Pubitemid 39587547)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.23
, pp. 8059-8067
-
-
DeGraffenried, L.A.1
Friedrichs, W.E.2
Russell, D.H.3
Donzis, E.J.4
Middleton, A.K.5
Silva, J.M.6
Roth, R.A.7
Hidalgo, M.8
-
7
-
-
84860390340
-
Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer
-
Sanchez CG, Ma CX, Crowder RJ, et al: Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer. Breast Cancer Res 13:R21, 2011
-
(2011)
Breast Cancer Res
, vol.13
-
-
Sanchez, C.G.1
Ma, C.X.2
Crowder, R.J.3
-
8
-
-
78650339362
-
Intrinsic breast tumor subtypes, race, and long-term survival in the Carolina Breast Cancer Study
-
O'Brien KM, Cole SR, Tse CK, et al: Intrinsic breast tumor subtypes, race, and long-term survival in the Carolina Breast Cancer Study. Clin Cancer Res 16:6100-6110, 2010
-
(2010)
Clin Cancer Res
, vol.16
, pp. 6100-6110
-
-
O'brien, K.M.1
Cole, S.R.2
Tse, C.K.3
-
9
-
-
84863078767
-
Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer
-
Baselga J, Campone M, Piccart M, et al: Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer. N Engl J Med 366:520-529, 2012
-
(2012)
N Engl J Med
, vol.366
, pp. 520-529
-
-
Baselga, J.1
Campone, M.2
Piccart, M.3
-
10
-
-
84864773253
-
Everolimus for postmenopausal women with advanced breast cancer: Updated results of Bolero-2 phase III trial
-
suppl; abstr 559
-
Piccart-Gebhart MJ, Noguchi S, Pritchard KI, et al: Everolimus for postmenopausal women with advanced breast cancer: Updated results of Bolero-2 phase III trial. J Clin Oncol 30:21s, 2012 (suppl; abstr 559)
-
(2012)
J Clin Oncol
, vol.30
-
-
Piccart-Gebhart, M.J.1
Noguchi, S.2
Pritchard, K.I.3
-
11
-
-
84864558874
-
Randomized phase II trial of everolimus in combination with tamoxifen in patients with hormone receptorpositive, human epidermal growth factor receptor 2-negative metastatic breast cancer with prior exposure to aromatase inhibitors: A GINECO study
-
Bachelot T, Bourgier C, Cropet C, et al: Randomized phase II trial of everolimus in combination with tamoxifen in patients with hormone receptorpositive, human epidermal growth factor receptor 2-negative metastatic breast cancer with prior exposure to aromatase inhibitors: A GINECO study. J Clin Oncol 30:2718-2724, 2012
-
(2012)
J Clin Oncol
, vol.30
, pp. 2718-2724
-
-
Bachelot, T.1
Bourgier, C.2
Cropet, C.3
-
12
-
-
84872537904
-
-
Genitourinary Cancers Symposium, San Francisco, CA, March 5-7, 2010
-
Chulikavit M, Casciano R, Stern L, et al: Cost of treating patients with advanced renal cell carcinoma with everolimus versus temsirolimus after failure on sunitinib or sorafenib. 2010 Genitourinary Cancers Symposium, San Francisco, CA, March 5-7, 2010
-
(2010)
Cost of Treating Patients with Advanced Renal Cell Carcinoma with Everolimus Versus Temsirolimus after Failure on Sunitinib or Sorafenib
-
-
Chulikavit, M.1
Casciano, R.2
Stern, L.3
-
13
-
-
84872518645
-
Randomized phase III placebocontrolled trial of letrozole plus oral temsirolimus as first-line endocrine therapy in postmenopausal women with locally advanced or metastatic breast cancer
-
Wolff AC, Lazar AA, Bondarenko I, et al: Randomized phase III placebocontrolled trial of letrozole plus oral temsirolimus as first-line endocrine therapy in postmenopausal women with locally advanced or metastatic breast cancer. J Clin Oncol 31:195-202, 2013
-
(2013)
J Clin Oncol
, vol.31
, pp. 195-202
-
-
Wolff, A.C.1
Lazar, A.A.2
Bondarenko, I.3
-
14
-
-
84872515250
-
Safety of everolimus for women over age 65 with advanced breast cancer (BC): 12.5-month follow-up of BOLERO-2
-
abstr 104
-
Rugo HS, Burris HA III, Gnant M, et al: Safety of everolimus for women over age 65 with advanced breast cancer (BC): 12.5-month follow-up of BOLERO-2. J Clin Oncol 30, 2012 (abstr 104)
-
(2012)
J Clin Oncol
, vol.30
-
-
Rugo, H.S.1
Burris III, H.A.2
Gnant, M.3
-
15
-
-
66849136781
-
Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer
-
Baselga J, Semiglazov V, van Dam P, et al: Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer. J Clin Oncol 27:2630-2637, 2009
-
(2009)
J Clin Oncol
, vol.27
, pp. 2630-2637
-
-
Baselga, J.1
Semiglazov, V.2
Van Dam, P.3
-
16
-
-
34548083672
-
Cytochrome P450 3A polymorphisms and immunosuppressive drugs: An update
-
DOI 10.2217/14622416.8.7.835
-
Anglicheau D, Legendre C, Beaune P, et al: Cytochrome P450 3A polymorphisms and immunosuppressive drugs: An update. Pharmacogenomics 8:835-849, 2007 (Pubitemid 47288980)
-
(2007)
Pharmacogenomics
, vol.8
, Issue.7
, pp. 835-849
-
-
Anglicheau, D.1
Legendre, C.L.2
Beaune, P.3
Thervet, E.4
-
17
-
-
84858842073
-
Tumor genetic testing for patient selection in phase i clinical trials: The case of PI3K inhibitors
-
Juric D, Baselga J: Tumor genetic testing for patient selection in phase I clinical trials: The case of PI3K inhibitors. J Clin Oncol 30:765-766, 2012
-
(2012)
J Clin Oncol
, vol.30
, pp. 765-766
-
-
Juric, D.1
Baselga, J.2
-
18
-
-
40949118437
-
Temsirolimus, an inhibitor of mammalian target of rapamycin
-
DOI 10.1158/1078-0432.CCR-07-4719
-
Rini BI: Temsirolimus, an inhibitor of mammalian target of rapamycin. Clinical Cancer Res 14:1286-1290, 2008 (Pubitemid 351413905)
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.5
, pp. 1286-1290
-
-
Rini, B.I.1
-
19
-
-
48949117156
-
Everolimus: An update on the mechanism of action, pharmacokinetics and recent clinical trials
-
DOI 10.1517/17425255.4.6.807
-
Sanchez-Fructuoso AI: Everolimus: An update on the mechanism of action, pharmacokinetics and recent clinical trials. Expert Opin Drug Metab Toxicol 4:807-819, 2008 (Pubitemid 352003202)
-
(2008)
Expert Opinion on Drug Metabolism and Toxicology
, vol.4
, Issue.6
, pp. 807-819
-
-
Sanchez-Fructuoso, A.I.1
-
20
-
-
84868514318
-
MTOR inhibitors in breast cancer: A systematic review
-
Zagouri F, Sergentanis TN, Chrysikos D, et al: MTOR inhibitors in breast cancer: A systematic review. Gynecol Oncol 127:662-672, 2012
-
(2012)
Gynecol Oncol
, vol.127
, pp. 662-672
-
-
Zagouri, F.1
Sergentanis, T.N.2
Chrysikos, D.3
-
21
-
-
70249128382
-
Enhancing the efficacy of hormonal agents with selected targeted agents
-
Johnston SR: Enhancing the efficacy of hormonal agents with selected targeted agents. Clin Breast Cancer 9:S28-S36, 2009 (suppl 1)
-
(2009)
Clin Breast Cancer
, vol.9
, Issue.SUPPL. 1
-
-
Johnston, S.R.1
-
22
-
-
79551576468
-
Mechanisms of endocrine resistance in breast cancer
-
Osborne CK, Schiff R: Mechanisms of endocrine resistance in breast cancer. Annu Rev Med 62:233-247, 2011
-
(2011)
Annu Rev Med
, vol.62
, pp. 233-247
-
-
Osborne, C.K.1
Schiff, R.2
-
23
-
-
84864512253
-
Combination anastrozole and fulvestrant in metastatic breast cancer
-
Mehta RS, Barlow WE, Albain KS, et al: Combination anastrozole and fulvestrant in metastatic breast cancer. N Engl J Med 367:435-444, 2012
-
(2012)
N Engl J Med
, vol.367
, pp. 435-444
-
-
Mehta, R.S.1
Barlow, W.E.2
Albain, K.S.3
-
24
-
-
84863892191
-
FACT: An open-label randomized phase III study of fulvestrant and anastrozole in combination compared with anastrozole alone as first-line therapy for patients with receptor-positive postmenopausal breast cancer
-
Bergh J, Jonsson PE, Lidbrink EK, et al: FACT: An open-label randomized phase III study of fulvestrant and anastrozole in combination compared with anastrozole alone as first-line therapy for patients with receptor-positive postmenopausal breast cancer. J Clin Oncol 30:1919-1925, 2012
-
(2012)
J Clin Oncol
, vol.30
, pp. 1919-1925
-
-
Bergh, J.1
Jonsson, P.E.2
Lidbrink, E.K.3
-
25
-
-
68949102467
-
Lower-dose vs high-dose oral estradiol therapy of hormone receptor-positive, aromatase inhibitor-resistant advanced breast cancer: A phase 2 randomized study
-
Ellis MJ, Gao F, Dehdashti F, et al: Lower-dose vs high-dose oral estradiol therapy of hormone receptor-positive, aromatase inhibitor-resistant advanced breast cancer: A phase 2 randomized study. JAMA 302:774-780, 2009
-
(2009)
JAMA
, vol.302
, pp. 774-780
-
-
Ellis, M.J.1
Gao, F.2
Dehdashti, F.3
|