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Volumn 14, Issue 1, 2013, Pages

Potential contribution of SIM2 and ETS2 functional polymorphisms in Down syndrome associated malignancies

Author keywords

Acute lymphoblastic leukemia; Breast cancer; Down syndrome; ETS2; Oral cancer; SIM2

Indexed keywords

E26 ONCOGENE HOMOLOG 2; SINGLE MINDED 2 PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84872572052     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-14-12     Document Type: Article
Times cited : (7)

References (62)
  • 1
    • 0342905433 scopus 로고    scopus 로고
    • Risks of leukemia and solid tumors in individuals with Down's syndrome
    • 10.1016/S0140-6736(99)05264-2, 10675114
    • Hasle H, Clemmensen IH, Mikkelsen M. Risks of leukemia and solid tumors in individuals with Down's syndrome. Lancet 2000, 355:165-169. 10.1016/S0140-6736(99)05264-2, 10675114.
    • (2000) Lancet , vol.355 , pp. 165-169
    • Hasle, H.1    Clemmensen, I.H.2    Mikkelsen, M.3
  • 2
    • 57649201350 scopus 로고    scopus 로고
    • FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease
    • 10.1186/gb-2008-9-12-r170, 2646274, 19061490
    • Chen R, Morgan AA, Dudley J, Deshpande T, Li L, Kodama K, Chiang AP, Butte AJ. FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease. Genome Biol 2008, 9:R170. 10.1186/gb-2008-9-12-r170, 2646274, 19061490.
    • (2008) Genome Biol , vol.9
    • Chen, R.1    Morgan, A.A.2    Dudley, J.3    Deshpande, T.4    Li, L.5    Kodama, K.6    Chiang, A.P.7    Butte, A.J.8
  • 3
    • 0030750422 scopus 로고    scopus 로고
    • Single-minded-two genes, three chromosomes
    • Michaud J, Fan CM. Single-minded-two genes, three chromosomes. Genome Res 1997, 7:569-571.
    • (1997) Genome Res , vol.7 , pp. 569-571
    • Michaud, J.1    Fan, C.M.2
  • 4
    • 0030200752 scopus 로고    scopus 로고
    • The mammalian single-minded (SIM) gene: mouse cDNA structure and diencephalic expression indicate a candidate gene for Down syndrome
    • 10.1006/geno.1996.0332, 8661114
    • Yamaki A, Noda S, Kudoh J, Shindoh N, Maeda H, Minoshima S, Kawasaki K, Shimizu Y, Shimizu N. The mammalian single-minded (SIM) gene: mouse cDNA structure and diencephalic expression indicate a candidate gene for Down syndrome. Genomics 1996, 35:136-143. 10.1006/geno.1996.0332, 8661114.
    • (1996) Genomics , vol.35 , pp. 136-143
    • Yamaki, A.1    Noda, S.2    Kudoh, J.3    Shindoh, N.4    Maeda, H.5    Minoshima, S.6    Kawasaki, K.7    Shimizu, Y.8    Shimizu, N.9
  • 5
    • 0028172292 scopus 로고
    • Control of CNS midline transcription by asymmetric E-box-like elements: similarity to xenobiotic responsive regulation
    • Wharton KA, Franks RG, Kasai Y, Crews ST. Control of CNS midline transcription by asymmetric E-box-like elements: similarity to xenobiotic responsive regulation. Development 1994, 120:3563-3569.
    • (1994) Development , vol.120 , pp. 3563-3569
    • Wharton, K.A.1    Franks, R.G.2    Kasai, Y.3    Crews, S.T.4
  • 6
    • 0036783335 scopus 로고    scopus 로고
    • Pharmacogenomics, regulation and signaling pathways of phase I and II drugmetabolizing enzymes
    • 10.2174/1389200023337171, 12369894
    • Rushmore TH, Kong AN. Pharmacogenomics, regulation and signaling pathways of phase I and II drugmetabolizing enzymes. Curr Drug Metab 2002, 3:481-490. 10.2174/1389200023337171, 12369894.
    • (2002) Curr Drug Metab , vol.3 , pp. 481-490
    • Rushmore, T.H.1    Kong, A.N.2
  • 7
    • 0028987872 scopus 로고
    • The aryl hydrocarbon receptor complex
    • 10.1146/annurev.pa.35.040195.001515, 7598497
    • Hankinson O. The aryl hydrocarbon receptor complex. Annu Rev Pharmacol Toxicol 1995, 35:307-340. 10.1146/annurev.pa.35.040195.001515, 7598497.
    • (1995) Annu Rev Pharmacol Toxicol , vol.35 , pp. 307-340
    • Hankinson, O.1
  • 8
    • 0033990325 scopus 로고    scopus 로고
    • Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis
    • 10.1016/S0006-2952(99)00310-X, 10605936
    • Nebert DW, Roe AL, Dieter MZ, Solis WA, Yang Y, Dalton TP. Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis. Biochem Pharmacol 2000, 59:65-85. 10.1016/S0006-2952(99)00310-X, 10605936.
    • (2000) Biochem Pharmacol , vol.59 , pp. 65-85
    • Nebert, D.W.1    Roe, A.L.2    Dieter, M.Z.3    Solis, W.A.4    Yang, Y.5    Dalton, T.P.6
  • 9
    • 0037447077 scopus 로고    scopus 로고
    • Identification of Down's syndrome critical locus gene SIM2-s as a drug therapy target for solid tumors
    • 10.1073/pnas.0831000100, 153629, 12676991
    • Young MPD, Tress M, Narayanan R. Identification of Down's syndrome critical locus gene SIM2-s as a drug therapy target for solid tumors. Proc Natl Acad Sci 2003, 100:4760-4765. 10.1073/pnas.0831000100, 153629, 12676991.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 4760-4765
    • Young, M.P.D.1    Tress, M.2    Narayanan, R.3
  • 10
    • 24644525067 scopus 로고    scopus 로고
    • Inhibition of single minded 2 gene expression mediates tumor-selective apoptosis and differentiation in human colon cancer cells
    • 10.1073/pnas.0505484102, 1200285, 16129820
    • Aleman MJ, Young MPD. Inhibition of single minded 2 gene expression mediates tumor-selective apoptosis and differentiation in human colon cancer cells. Proc Natl Acad Sci 2005, 102:12765-12770. 10.1073/pnas.0505484102, 1200285, 16129820.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 12765-12770
    • Aleman, M.J.1    Young, M.P.D.2
  • 15
    • 0347479365 scopus 로고    scopus 로고
    • Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis
    • 10.1016/S0969-9961(03)00107-4, 14678752
    • Wolvetang EJ, Bradfield OM, Hatzistavrou T, Crack PJ, Busciglio J, Kola I, Hertzog PJ. Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis. Neurobiol Dis 2003, 14:349-356. 10.1016/S0969-9961(03)00107-4, 14678752.
    • (2003) Neurobiol Dis , vol.14 , pp. 349-356
    • Wolvetang, E.J.1    Bradfield, O.M.2    Hatzistavrou, T.3    Crack, P.J.4    Busciglio, J.5    Kola, I.6    Hertzog, P.J.7
  • 16
    • 0142075827 scopus 로고    scopus 로고
    • The chromosome 21 transcription factor ETS2 transactivates the beta-APP promoter: implications for Down syndrome
    • 10.1016/S0167-4781(03)00121-0, 12890557
    • Wolvetang EW, Bradfield OM, Tymms M, Zavarsek S, Hatzistavrou T, Kola I, Hertzog PJ. The chromosome 21 transcription factor ETS2 transactivates the beta-APP promoter: implications for Down syndrome. Biochim Biophys Acta 2003, 1628:105-110. 10.1016/S0167-4781(03)00121-0, 12890557.
    • (2003) Biochim Biophys Acta , vol.1628 , pp. 105-110
    • Wolvetang, E.W.1    Bradfield, O.M.2    Tymms, M.3    Zavarsek, S.4    Hatzistavrou, T.5    Kola, I.6    Hertzog, P.J.7
  • 17
    • 0025580727 scopus 로고
    • Molecular analysis of the ets genes and their products
    • Watson DK, Ascione R, Papas TS. Molecular analysis of the ets genes and their products. Crit Rev Oncog 1990, 1:409-436.
    • (1990) Crit Rev Oncog , vol.1 , pp. 409-436
    • Watson, D.K.1    Ascione, R.2    Papas, T.S.3
  • 19
    • 0026689098 scopus 로고
    • The ets gene family
    • 10.1016/0968-0004(92)90404-W, 1502727
    • Macleod K, Leprince D, Stehelin D. The ets gene family. Trends Biochem Sci 1992, 17:251-256. 10.1016/0968-0004(92)90404-W, 1502727.
    • (1992) Trends Biochem Sci , vol.17 , pp. 251-256
    • Macleod, K.1    Leprince, D.2    Stehelin, D.3
  • 20
    • 0027458366 scopus 로고
    • The Ets family of transcription factors
    • 10.1111/j.1432-1033.1993.tb19864.x, 8425553
    • Wasylyk B, Hahn SL, Giovane A. The Ets family of transcription factors. Eur J Biochem 1993, 211:7-18. 10.1111/j.1432-1033.1993.tb19864.x, 8425553.
    • (1993) Eur J Biochem , vol.211 , pp. 7-18
    • Wasylyk, B.1    Hahn, S.L.2    Giovane, A.3
  • 21
    • 0002630906 scopus 로고    scopus 로고
    • The ETS family of Transcriptional regulators
    • Switzerland: Birkhauser Verlag: Basel, Yaniv M, Ghysdael J, Volume 1
    • Ghysdael J, Boureux A. The ETS family of Transcriptional regulators. In The ETS family of Transcriptional regulators. 1997, 29-88. Switzerland: Birkhauser Verlag: Basel, Yaniv M, Ghysdael J, Volume 1.
    • (1997) In The ETS family of Transcriptional regulators. , pp. 29-88
    • Ghysdael, J.1    Boureux, A.2
  • 22
    • 0032540454 scopus 로고    scopus 로고
    • Ets trsnscription factor and human disease
    • Dittmer J, Nordheim A. Ets trsnscription factor and human disease. Biochim Biophys Acta 1998, 1377:F1-F11.
    • (1998) Biochim Biophys Acta , vol.1377
    • Dittmer, J.1    Nordheim, A.2
  • 24
    • 0032582476 scopus 로고    scopus 로고
    • Specification of neuronal connectivity: ETS marks the spot
    • 10.1016/S0092-8674(00)81762-6, 9814701
    • Ghosh A, Kolodkin AL. Specification of neuronal connectivity: ETS marks the spot. Cell 1998, 95:303-306. 10.1016/S0092-8674(00)81762-6, 9814701.
    • (1998) Cell , vol.95 , pp. 303-306
    • Ghosh, A.1    Kolodkin, A.L.2
  • 26
    • 0031447517 scopus 로고    scopus 로고
    • The ETS-domain transcription factor family
    • 10.1016/S1357-2725(97)00086-1, 9570133
    • Sharrocks AD, Brown AL, Ling Y, Yates PR. The ETS-domain transcription factor family. Int J Biochem Cell Biol 1997, 29:1371-1387. 10.1016/S1357-2725(97)00086-1, 9570133.
    • (1997) Int J Biochem Cell Biol , vol.29 , pp. 1371-1387
    • Sharrocks, A.D.1    Brown, A.L.2    Ling, Y.3    Yates, P.R.4
  • 27
    • 4043134617 scopus 로고    scopus 로고
    • Triplex DNA-mediated downregulation of Ets2 expression results in growth inhibition and apoptosis in human prostate cancer cells
    • 10.1093/nar/gkh744, 514370, 15314206
    • Carbone GM, Napoli S, Valentini A, Cavalli F, Watson DK, Catapano CV. Triplex DNA-mediated downregulation of Ets2 expression results in growth inhibition and apoptosis in human prostate cancer cells. Nucl Acids Res 2004, 32:4358-4367. 10.1093/nar/gkh744, 514370, 15314206.
    • (2004) Nucl Acids Res , vol.32 , pp. 4358-4367
    • Carbone, G.M.1    Napoli, S.2    Valentini, A.3    Cavalli, F.4    Watson, D.K.5    Catapano, C.V.6
  • 28
    • 0034684619 scopus 로고    scopus 로고
    • Ets target genes: past, present and future
    • 10.1038/sj.onc.1204034, 11175369
    • Sementchenko VI, Watson DK. Ets target genes: past, present and future. Oncogene 2000, 19:6533-6548. 10.1038/sj.onc.1204034, 11175369.
    • (2000) Oncogene , vol.19 , pp. 6533-6548
    • Sementchenko, V.I.1    Watson, D.K.2
  • 29
    • 0038719698 scopus 로고    scopus 로고
    • Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter
    • 10.1074/jbc.M209480200, 12637547
    • Baker KM, Wei G, Schaffner AE, Ostrowski MC. Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter. J Biol Chem 2003, 278:17876-17884. 10.1074/jbc.M209480200, 12637547.
    • (2003) J Biol Chem , vol.278 , pp. 17876-17884
    • Baker, K.M.1    Wei, G.2    Schaffner, A.E.3    Ostrowski, M.C.4
  • 31
    • 65349165222 scopus 로고    scopus 로고
    • ETS2 and ERG promote megakaryopoiesis and synergize with alterations in GATA-1 to immortalize hematopoietic progenitor cells
    • Stankiewicz MJ, Crispino JD. ETS2 and ERG promote megakaryopoiesis and synergize with alterations in GATA-1 to immortalize hematopoietic progenitor cells. Blood 2009, 113:1347-3337.
    • (2009) Blood , vol.113 , pp. 1347-3337
    • Stankiewicz, M.J.1    Crispino, J.D.2
  • 33
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucl Acid Res 1988, 16:1215.
    • (1988) Nucl Acid Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 35
    • 0041857847 scopus 로고    scopus 로고
    • Pedigree disequilibrium tests for multilocus haplotypes
    • 10.1002/gepi.10252, 12916020
    • Dudbridge F. Pedigree disequilibrium tests for multilocus haplotypes. Genet Epidemiol 2003, 25(2):115-121. 10.1002/gepi.10252, 12916020.
    • (2003) Genet Epidemiol , vol.25 , Issue.2 , pp. 115-121
    • Dudbridge, F.1
  • 36
    • 28444496622 scopus 로고    scopus 로고
    • Extension of multifactor dimensionality reduction for identifying multilocus effects in the GAW14 simulated data
    • 10.1186/1471-2156-6-S1-S145, 1866790, 16451605
    • Mei H, Ma D, Ashley-Koch A, Martin ER. Extension of multifactor dimensionality reduction for identifying multilocus effects in the GAW14 simulated data. BMC Genet 2005, 6:S145-S149. 10.1186/1471-2156-6-S1-S145, 1866790, 16451605.
    • (2005) BMC Genet , vol.6
    • Mei, H.1    Ma, D.2    Ashley-Koch, A.3    Martin, E.R.4
  • 37
    • 34548032852 scopus 로고    scopus 로고
    • Statistical power calculations
    • 10.2527/jas.2006-449, 17060421
    • Lenth RV. Statistical power calculations. J Anim Sci 2007, 85:E24-E29. 10.2527/jas.2006-449, 17060421.
    • (2007) J Anim Sci , vol.85
    • Lenth, R.V.1
  • 38
    • 80955139749 scopus 로고    scopus 로고
    • Exploratory investigation on functional significance of ETS2 and SIM2 genes in Down syndrome
    • Chatterjee A, Dutta S, Sinha S, Mukhopadhyay K. Exploratory investigation on functional significance of ETS2 and SIM2 genes in Down syndrome. Disease Markers 2011, 31:247-257.
    • (2011) Disease Markers , vol.31 , pp. 247-257
    • Chatterjee, A.1    Dutta, S.2    Sinha, S.3    Mukhopadhyay, K.4
  • 39
    • 79951675833 scopus 로고    scopus 로고
    • Differential expression of tartrate-resistant acid phosphatase isoforms 5a and 5b by tumor and stromal cells in human metastatic bone disease
    • 10.1007/s10585-010-9358-4, 20967488
    • Zenger S, He W, Ek-Rylander B, Vassiliou D, Wedin R, Bauer H, Andersson G. Differential expression of tartrate-resistant acid phosphatase isoforms 5a and 5b by tumor and stromal cells in human metastatic bone disease. Clin Exp Metastasis 2011, 28(1):65-73. 10.1007/s10585-010-9358-4, 20967488.
    • (2011) Clin Exp Metastasis , vol.28 , Issue.1 , pp. 65-73
    • Zenger, S.1    He, W.2    Ek-Rylander, B.3    Vassiliou, D.4    Wedin, R.5    Bauer, H.6    Andersson, G.7
  • 41
    • 33645753197 scopus 로고    scopus 로고
    • Primary and secondary transcriptional effects in the developing human down syndrome brain and heart
    • 10.1186/gb-2005-6-13-r107, 1414106, 16420667
    • Mao R, Wang X, Spitznagel EL, Frelin LP, Ting JC, Ding H, Kim JW, Ruczinski I, Downey TJ, Pevsner J. Primary and secondary transcriptional effects in the developing human down syndrome brain and heart. Genome Biol 2005, 6(13):R107. 10.1186/gb-2005-6-13-r107, 1414106, 16420667.
    • (2005) Genome Biol , vol.6 , Issue.13
    • Mao, R.1    Wang, X.2    Spitznagel, E.L.3    Frelin, L.P.4    Ting, J.C.5    Ding, H.6    Kim, J.W.7    Ruczinski, I.8    Downey, T.J.9    Pevsner, J.10
  • 43
    • 34548496286 scopus 로고    scopus 로고
    • Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy
    • 10.1186/1471-2164-8-268, 1964766, 17683628
    • Conti A, Fabbrini F, D'Agostino P, Negri R, Greco D, Genesio R, D'Armiento M, Olla C, Paladini D, Zannini M, Nitsch L. Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy. BMC Genomics 2007, 8:268. 10.1186/1471-2164-8-268, 1964766, 17683628.
    • (2007) BMC Genomics , vol.8 , pp. 268
    • Conti, A.1    Fabbrini, F.2    D'Agostino, P.3    Negri, R.4    Greco, D.5    Genesio, R.6    D'Armiento, M.7    Olla, C.8    Paladini, D.9    Zannini, M.10    Nitsch, L.11
  • 44
    • 39649103820 scopus 로고    scopus 로고
    • Identification of dysregulated genes in lymphocytes from children with down syndrome
    • 10.1139/G07-100, 18356936
    • Sommer CA, Pavarino-Bertelli EC, Goloni-Bertollo EM, Henrique-Silva F. Identification of dysregulated genes in lymphocytes from children with down syndrome. Genome 2008, 51:19-29. 10.1139/G07-100, 18356936.
    • (2008) Genome , vol.51 , pp. 19-29
    • Sommer, C.A.1    Pavarino-Bertelli, E.C.2    Goloni-Bertollo, E.M.3    Henrique-Silva, F.4
  • 45
    • 36448964118 scopus 로고    scopus 로고
    • Gene expression proWling in the adult down syndrome brain
    • 10.1016/j.ygeno.2007.08.005, 17950572
    • Lockstone HE, Harris LW, Swatton JE, Wayland MT, Holland AJ, Bahn S. Gene expression proWling in the adult down syndrome brain. Genomics 2007, 90:647-660. 10.1016/j.ygeno.2007.08.005, 17950572.
    • (2007) Genomics , vol.90 , pp. 647-660
    • Lockstone, H.E.1    Harris, L.W.2    Swatton, J.E.3    Wayland, M.T.4    Holland, A.J.5    Bahn, S.6
  • 47
    • 67651124806 scopus 로고    scopus 로고
    • Molecular genetic analysis of down syndrome
    • 10.1007/s00439-009-0696-8, 19526251
    • Patterson D. Molecular genetic analysis of down syndrome. Hum Genet 2009, 126:195-214. 10.1007/s00439-009-0696-8, 19526251.
    • (2009) Hum Genet , vol.126 , pp. 195-214
    • Patterson, D.1
  • 51
    • 0037256549 scopus 로고    scopus 로고
    • Expression of H-ficolin/Hakata antigen, mannose-binding lectin-associated serine protease (MASP)-1 and MASP-3 by human glioma cell line T98G
    • 10.1093/intimm/dxg008, 12502731
    • Kuraya M, Matsushita M, Endo Y, Thiel S, Fujita T. Expression of H-ficolin/Hakata antigen, mannose-binding lectin-associated serine protease (MASP)-1 and MASP-3 by human glioma cell line T98G. Int Immunol 2003, 15(1):109-117. 10.1093/intimm/dxg008, 12502731.
    • (2003) Int Immunol , vol.15 , Issue.1 , pp. 109-117
    • Kuraya, M.1    Matsushita, M.2    Endo, Y.3    Thiel, S.4    Fujita, T.5
  • 52
    • 36649023670 scopus 로고    scopus 로고
    • Differential expression of Na+/K + -ATPase alpha-subunits in mouse hippocampal interneurones and pyramidal cells
    • 2375485, 17947306
    • Richards KS, Bommert K, Szabo G, Miles R. Differential expression of Na+/K + -ATPase alpha-subunits in mouse hippocampal interneurones and pyramidal cells. J Physiol 2007, 585(Pt 2):491-505. 2375485, 17947306.
    • (2007) J Physiol , vol.585 , Issue.PART 2 , pp. 491-505
    • Richards, K.S.1    Bommert, K.2    Szabo, G.3    Miles, R.4
  • 53
    • 70349847251 scopus 로고    scopus 로고
    • Expression and prognostic significance of THBS1, Cyr61 and CTGF in esophageal squamous cell carcinoma
    • 10.1186/1471-2407-9-291, 2748090, 19698122
    • Zhou ZQ, Cao WH, Xie JJ, Lin J, Shen ZY, Zhang QY, Shen JH, Xu LY, Li EM. Expression and prognostic significance of THBS1, Cyr61 and CTGF in esophageal squamous cell carcinoma. BMC Cancer 2009, 9:291. 10.1186/1471-2407-9-291, 2748090, 19698122.
    • (2009) BMC Cancer , vol.9 , pp. 291
    • Zhou, Z.Q.1    Cao, W.H.2    Xie, J.J.3    Lin, J.4    Shen, Z.Y.5    Zhang, Q.Y.6    Shen, J.H.7    Xu, L.Y.8    Li, E.M.9
  • 57
    • 0034780112 scopus 로고    scopus 로고
    • Frequent allelic imbalance and loss of protein expression of the DNA repair gene hOGG1 in head and neck squamous cell carcinoma
    • 10.1038/labinvest.3780356, 11598155
    • Fan CY, Liu KL, Huang HY, Barnes EL, Swalsky PA, Bakker A, Woods J, Finkelstein SD. Frequent allelic imbalance and loss of protein expression of the DNA repair gene hOGG1 in head and neck squamous cell carcinoma. Lab Investig 2001, 81:1429-1438. 10.1038/labinvest.3780356, 11598155.
    • (2001) Lab Investig , vol.81 , pp. 1429-1438
    • Fan, C.Y.1    Liu, K.L.2    Huang, H.Y.3    Barnes, E.L.4    Swalsky, P.A.5    Bakker, A.6    Woods, J.7    Finkelstein, S.D.8
  • 60
    • 77952020384 scopus 로고    scopus 로고
    • The role of chromosome 21 in hematology and oncology
    • Fonatsch C. The role of chromosome 21 in hematology and oncology. Genes Chromosomes Cancer 2010, 49:497-508.
    • (2010) Genes Chromosomes Cancer , vol.49 , pp. 497-508
    • Fonatsch, C.1
  • 61
    • 38649123691 scopus 로고    scopus 로고
    • Acute leukemias in children with down syndrome
    • 10.1016/j.pcl.2007.11.001, 18242315
    • Zwaan MC, Reinhardt D, Hitzler J, Vyas P. Acute leukemias in children with down syndrome. Pediatr Clin North Am 2008, 55:53-70. 10.1016/j.pcl.2007.11.001, 18242315.
    • (2008) Pediatr Clin North Am , vol.55 , pp. 53-70
    • Zwaan, M.C.1    Reinhardt, D.2    Hitzler, J.3    Vyas, P.4


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