-
1
-
-
17344369139
-
Directing NGF's actions: It's a rap
-
DOI 10.1038/ncb0405-338
-
Directing NGF's actions: it's a Rap. Stork PJ, Nat Cell Biol 2005 7 338 339 10.1038/ncb0405-338 15803132 (Pubitemid 40533122)
-
(2005)
Nature Cell Biology
, vol.7
, Issue.4
, pp. 338-339
-
-
Stork, P.J.1
-
2
-
-
33847392514
-
Untangling the signalling wires
-
DOI 10.1038/ncb0307-247, PII NCB0307-247
-
Untangling the signalling wires. Kholodenko BN, Nat Cell Biol 2007 9 247 249 10.1038/ncb0307-247 17330115 (Pubitemid 46344602)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.3
, pp. 247-249
-
-
Kholodenko, B.N.1
-
3
-
-
0028872649
-
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
-
10.1016/0092-8674(95)90401-8 7834738
-
Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Marshall CJ, Cell 1995 80 179 185 10.1016/0092-8674(95)90401-8 7834738
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
4
-
-
33847355217
-
Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate
-
DOI 10.1038/ncb1543, PII NCB1543
-
Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate. Santos SD, Verveer PJ, Bastiaens PI, Nat Cell Biol 2007 9 324 330 10.1038/ncb1543 17310240 (Pubitemid 46344612)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.3
, pp. 324-330
-
-
Santos, S.D.M.1
Verveer, P.J.2
Bastiaens, P.I.H.3
-
5
-
-
0036051342
-
Molecular interpretation of ERK signal duration by immediate early gene products
-
12134156
-
Molecular interpretation of ERK signal duration by immediate early gene products. Murphy LO, Smith S, Chen RH, Fingar DC, Blenis J, Nat Cell Biol 2002 4 556 564 12134156
-
(2002)
Nat Cell Biol
, vol.4
, pp. 556-564
-
-
Murphy, L.O.1
Smith, S.2
Chen, R.H.3
Fingar, D.C.4
Blenis, J.5
-
6
-
-
33845607123
-
Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling
-
DOI 10.1038/nature05269, PII NATURE05269
-
Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling. Daniels MA, Teixeiro E, Gill J, Hausmann B, Roubaty D, Holmberg K, Werlen G, Hollander GA, Gascoigne NR, Palmer E, Nature 2006 444 724 729 10.1038/nature05269 17086201 (Pubitemid 44949596)
-
(2006)
Nature
, vol.444
, Issue.7120
, pp. 724-729
-
-
Daniels, M.A.1
Teixeiro, E.2
Gill, J.3
Hausmann, B.4
Roubaty, D.5
Holmberg, K.6
Werlen, G.7
Hollander, G.A.8
Gascoigne, N.R.J.9
Palmer, E.10
-
7
-
-
45549102527
-
Dynamics of Proximal Signaling Events after TCR/CD8-Mediated Induction of Proliferation or Apoptosis in Mature CD8+ T Cells
-
18453590
-
Dynamics of Proximal Signaling Events after TCR/CD8-Mediated Induction of Proliferation or Apoptosis in Mature CD8+ T Cells. Wang X, Simeoni L, Lindquist JA, Saez-Rodriguez J, Ambach A, Gilles ED, Kliche S, Schraven B, J Immunol 2008 180 6703 6712 18453590
-
(2008)
J Immunol
, vol.180
, pp. 6703-6712
-
-
Wang, X.1
Simeoni, L.2
Lindquist, J.A.3
Saez-Rodriguez, J.4
Ambach, A.5
Gilles, E.D.6
Kliche, S.7
Schraven, B.8
-
8
-
-
84871406029
-
Analysis of TCR activation kinetics in primary human T cells upon focal or soluble stimulation
-
10.1016/j.jim.2012.11.006 23178863
-
Analysis of TCR activation kinetics in primary human T cells upon focal or soluble stimulation. Arndt B, Poltorak M, Kowtharapu BS, Reichardt P, Philipsen L, Lindquist JA, Schraven B, Simeoni L, J Immunol Methods 2013 387 276 283 10.1016/j.jim.2012.11.006 23178863
-
(2013)
J Immunol Methods
, vol.387
, pp. 276-283
-
-
Arndt, B.1
Poltorak, M.2
Kowtharapu, B.S.3
Reichardt, P.4
Philipsen, L.5
Lindquist, J.A.6
Schraven, B.7
Simeoni, L.8
-
9
-
-
0342313755
-
Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase Csk and is involved in regulation of T cell activation
-
DOI 10.1084/jem.191.9.1591
-
Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation. Brdicka T, Pavlistova D, Leo A, Bruyns E, Korinek V, Angelisova P, Scherer J, Shevchenko A, Hilgert I, Cerny J, et al. J Exp Med 2000 191 1591 1604 10.1084/jem.191.9.1591 10790433 (Pubitemid 30257355)
-
(2000)
Journal of Experimental Medicine
, vol.191
, Issue.9
, pp. 1591-1604
-
-
Brdicka, T.1
Pavlistova, D.2
Leo, A.3
Bruyns, E.4
Korinek, V.5
Angelisova, P.6
Scherer, J.7
Shevchenko, A.8
Shevchenko, A.9
Hilgert, I.10
Cerny, J.11
Drbal, K.12
Kuramitsu, Y.13
Kornacker, B.14
Horejsi, V.15
Schraven, B.16
-
10
-
-
0032530696
-
Sustained TCR signaling is required for mitogen-activated protein kinase activation and degranulation by cytotoxic T lymphocytes
-
Sustained TCR signaling is required for mitogen-activated protein kinase activation and degranulation by cytotoxic T lymphocytes. Berg NN, Puente LG, Dawicki W, Ostergaard HL, J Immunol 1998 161 2919 2924 9743353 (Pubitemid 28425714)
-
(1998)
Journal of Immunology
, vol.161
, Issue.6
, pp. 2919-2924
-
-
Berg, N.N.1
Puente, L.G.2
Dawicki, W.3
Ostergaard, H.L.4
-
11
-
-
0037338890
-
TCR ligand discrimination is enforced by competing ERK positive and SHP-I negative feedback pathways
-
DOI 10.1038/ni895
-
TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways. Stefanova I, Hemmer B, Vergelli M, Martin R, Biddison WE, Germain RN, Nat Immunol 2003 4 248 254 12577055 (Pubitemid 36322134)
-
(2003)
Nature Immunology
, vol.4
, Issue.3
, pp. 248-254
-
-
Stefanova, I.1
Hemmer, B.2
Vergelli, M.3
Martin, R.4
Biddison, W.E.5
Germain, R.N.6
-
12
-
-
27844541328
-
Modeling T cell antigen discrimination based on feedback control of digital ERK responses
-
DOI 10.1371/journal.pbio.0030356, e356
-
Modeling T cell antigen discrimination based on feedback control of digital ERK responses. Altan-Bonnet G, Germain RN, PLoS Biol 2005 3 356 10.1371/journal.pbio.0030356 16231973 (Pubitemid 41652444)
-
(2005)
PLoS Biology
, vol.3
, Issue.11
, pp. 1925-1938
-
-
Altan-Bonnet, G.1
Germain, R.N.2
-
13
-
-
50249105938
-
Tailoring T-cell receptor signals by proximal negative feedback mechanisms
-
10.1038/nri2397 18728635
-
Tailoring T-cell receptor signals by proximal negative feedback mechanisms. Acuto O, Di Bartolo V, Micheli F, Nat Rev Immunol 2008 8 699 712 10.1038/nri2397 18728635
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 699-712
-
-
Acuto, O.1
Di Bartolo, V.2
Micheli, F.3
-
14
-
-
34249293731
-
Regulation of peripheral T cell tolerance by the E3 ubiquitin ligase Cbl-b
-
DOI 10.1016/j.smim.2007.02.004, PII S1044532307000115, Molecular Mechanisms Supporting Peripheral T cell Tolerance: Potential Therapeutic Approaches to Autoimmunity and Allograft Rejection
-
Regulation of peripheral T cell tolerance by the E3 ubiquitin ligase Cbl-b. Loeser S, Penninger JM, Semin Immunol 2007 19 206 214 10.1016/j.smim.2007.02.004 17391982 (Pubitemid 46810290)
-
(2007)
Seminars in Immunology
, vol.19
, Issue.3
, pp. 206-214
-
-
Loeser, S.1
Penninger, J.M.2
-
15
-
-
33750530393
-
T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2
-
DOI 10.1084/jem.20060650
-
T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2. Dong S, Corre B, Foulon E, Dufour E, Veillette A, Acuto O, Michel F, J Exp Med 2006 203 2509 2518 10.1084/jem.20060650 17043143 (Pubitemid 44664620)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.11
, pp. 2509-2518
-
-
Dong, S.1
Corre, B.2
Foulon, E.3
Dufour, E.4
Veillette, A.5
Acuto, O.6
Michel, F.7
-
16
-
-
0033392493
-
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1
-
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1. Levkowitz G, Waterman H, Ettenberg SA, Katz M, Tsygankov AY, Alroy I, Lavi S, Iwai K, Reiss Y, Ciechanover A, et al. Mol Cell 1999 4 1029 1040 10.1016/S1097-2765(00)80231-2 10635327 (Pubitemid 30054908)
-
(1999)
Molecular Cell
, vol.4
, Issue.6
, pp. 1029-1040
-
-
Levkowitz, G.1
Waterman, H.2
Ettenberg, S.A.3
Katz, M.4
Tsygankov, A.Y.5
Alroy, I.6
Lavi, S.7
Iwai, K.8
Reiss, Y.9
Ciechanover, A.10
Lipkowitz, S.11
Yarden, Y.12
-
17
-
-
3142618052
-
Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations
-
DOI 10.1074/jbc.M404114200
-
Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations. Kassenbrock CK, Anderson SM, J Biol Chem 2004 279 28017 28027 10.1074/jbc.M404114200 15117950 (Pubitemid 38900072)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.27
, pp. 28017-28027
-
-
Kassenbrock, C.K.1
Anderson, S.M.2
-
18
-
-
0035854665
-
Cbl Promotes Ubiquitination of the T Cell Receptor zeta through an Adaptor Function of Zap-70
-
DOI 10.1074/jbc.M010738200
-
Cbl promotes ubiquitination of the T cell receptor zeta through an adaptor function of Zap-70. Wang HY, Altman Y, Fang D, Elly C, Dai Y, Shao Y, Liu YC, J Biol Chem 2001 276 26004 26011 10.1074/jbc.M010738200 11353765 (Pubitemid 37412808)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.28
, pp. 26004-26011
-
-
Wang, H.-Y.1
Altman, Y.2
Fang, D.3
Elly, C.4
Dai, Y.5
Shao, Y.6
Liu, Y.-C.7
-
19
-
-
0027421614
-
Phosphorylation of serine 59 of p56(lck) in activated T cells
-
Phosphorylation of serine 59 of p56lck in activated T cells. Watts JD, Sanghera JS, Pelech SL, Aebersold R, J Biol Chem 1993 268 23275 23282 8226850 (Pubitemid 23328046)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.31
, pp. 23275-23282
-
-
Watts, J.D.1
Sanghera, J.S.2
Pelech, S.L.3
Aebersold, R.4
-
20
-
-
0027164317
-
Phosphorylation of Ser-42 and Ser-59 in the N-terminal region of the tyrosine kinase p56(lck)
-
Phosphorylation of Ser-42 and Ser-59 in the N-terminal region of the tyrosine kinase p56lck. Winkler DG, Park I, Kim T, Payne NS, Walsh CT, Strominger JL, Shin J, Proc Natl Acad Sci USA 1993 90 5176 5180 10.1073/pnas.90.11.5176 8506364 (Pubitemid 23183000)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.11
, pp. 5176-5180
-
-
Winkler, D.G.1
Park, I.2
Kim, T.3
Payne, N.S.4
Walsh, C.T.5
Strominger, J.L.6
Shin, J.7
-
21
-
-
0028983399
-
Modification of Ser59 in the unique N-terminal region of tyrosine kinase p56lck regulates specificity of its Src homology 2 domain
-
10.1073/pnas.92.13.5778 7597029
-
Modification of Ser59 in the unique N-terminal region of tyrosine kinase p56lck regulates specificity of its Src homology 2 domain. Joung I, Kim T, Stolz LA, Payne G, Winkler DG, Walsh CT, Strominger JL, Shin J, Proc Natl Acad Sci USA 1995 92 5778 5782 10.1073/pnas.92.13.5778 7597029
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5778-5782
-
-
Joung, I.1
Kim, T.2
Stolz, L.A.3
Payne, G.4
Winkler, D.G.5
Walsh, C.T.6
Strominger, J.L.7
Shin, J.8
-
22
-
-
55249092772
-
Reduced Cbl phosphorylation and degradation of the zeta-chain of the T-cell receptor/CD3 complex in T cells with low Lck levels
-
10.1002/eji.200737837 18792408
-
Reduced Cbl phosphorylation and degradation of the zeta-chain of the T-cell receptor/CD3 complex in T cells with low Lck levels. Methi T, Berge T, Torgersen KM, Tasken K, Eur J Immunol 2008 38 2557 2563 10.1002/eji.200737837 18792408
-
(2008)
Eur J Immunol
, vol.38
, pp. 2557-2563
-
-
Methi, T.1
Berge, T.2
Torgersen, K.M.3
Tasken, K.4
-
23
-
-
28244434854
-
Short-interfering RNA-mediated Lck knockdown results in augmented downstream T cell responses
-
Short-interfering RNA-mediated Lck knockdown results in augmented downstream T cell responses. Methi T, Ngai J, Mahic M, Amarzguioui M, Vang T, Tasken K, J Immunol 2005 175 7398 7406 16301647 (Pubitemid 41713437)
-
(2005)
Journal of Immunology
, vol.175
, Issue.11
, pp. 7398-7406
-
-
Methi, T.1
Ngai, J.2
Mahic, M.3
Amarzguioui, M.4
Vang, T.5
Tasken, K.6
-
24
-
-
1642264751
-
Calcineurin B1 is essential for positive but not negative selection during thymocyte development
-
DOI 10.1016/S1074-7613(04)00052-4, PII S1074761304000524
-
Calcineurin B1 is essential for positive but not negative selection during thymocyte development. Neilson JR, Winslow MM, Hur EM, Crabtree GR, Immunity 2004 20 255 266 10.1016/S1074-7613(04)00052-4 15030770 (Pubitemid 38388228)
-
(2004)
Immunity
, vol.20
, Issue.3
, pp. 255-266
-
-
Neilson, J.R.1
Winslow, M.M.2
Hur, E.M.3
Crabtree, G.R.4
-
25
-
-
77953911933
-
Constitutively active Lck kinase in T cells drives antigen receptor signal transduction
-
10.1016/j.immuni.2010.05.011 20541955
-
Constitutively active Lck kinase in T cells drives antigen receptor signal transduction. Nika K, Soldani C, Salek M, Paster W, Gray A, Etzensperger R, Fugger L, Polzella P, Cerundolo V, Dushek O, et al. Immunity 2010 32 766 777 10.1016/j.immuni.2010.05.011 20541955
-
(2010)
Immunity
, vol.32
, pp. 766-777
-
-
Nika, K.1
Soldani, C.2
Salek, M.3
Paster, W.4
Gray, A.5
Etzensperger, R.6
Fugger, L.7
Polzella, P.8
Cerundolo, V.9
Dushek, O.10
-
26
-
-
0022352684
-
Perturbation of the T4 molecule transmits a negative signal to T cells
-
DOI 10.1084/jem.162.4.1294
-
Perturbation of the T4 molecule transmits a negative signal to T cells. Bank I, Chess L, J Exp Med 1985 162 1294 1303 10.1084/jem.162.4.1294 2413158 (Pubitemid 16225121)
-
(1985)
Journal of Experimental Medicine
, vol.162
, Issue.4
, pp. 1294-1303
-
-
Bank, I.1
Chess, L.2
-
27
-
-
0026784923
-
Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis
-
10.1084/jem.176.4.1099 1402655
-
Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis. Banda NK, Bernier J, Kurahara DK, Kurrle R, Haigwood N, Sekaly RP, Finkel TH, J Exp Med 1992 176 1099 1106 10.1084/jem.176.4.1099 1402655
-
(1992)
J Exp Med
, vol.176
, pp. 1099-1106
-
-
Banda, N.K.1
Bernier, J.2
Kurahara, D.K.3
Kurrle, R.4
Haigwood, N.5
Sekaly, R.P.6
Finkel, T.H.7
-
28
-
-
33645924074
-
A novel PKC regulates ERK activation and degranulation of cytotoxic T lymphocytes: Plasticity in PKC regulation of ERK
-
10.1002/eji.200535277 16552708
-
A novel PKC regulates ERK activation and degranulation of cytotoxic T lymphocytes: Plasticity in PKC regulation of ERK. Puente LG, He JS, Ostergaard HL, Eur J Immunol 2006 36 1009 1018 10.1002/eji.200535277 16552708
-
(2006)
Eur J Immunol
, vol.36
, pp. 1009-1018
-
-
Puente, L.G.1
He, J.S.2
Ostergaard, H.L.3
-
29
-
-
80053000911
-
The Transmembrane Adaptor Protein SIT Inhibits TCR-Mediated Signaling
-
10.1371/journal.pone.0023761 21957439
-
The Transmembrane Adaptor Protein SIT Inhibits TCR-Mediated Signaling. Arndt B, Krieger T, Kalinski T, Thielitz A, Reinhold D, Roessner A, Schraven B, Simeoni L, PLoS One 2011 6 23761 10.1371/journal.pone.0023761 21957439
-
(2011)
PLoS One
, vol.6
, pp. 523761
-
-
Arndt, B.1
Krieger, T.2
Kalinski, T.3
Thielitz, A.4
Reinhold, D.5
Roessner, A.6
Schraven, B.7
Simeoni, L.8
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