Of mice and men: The need for humanized mouse models to study human igg activity in Vivo

Journal of Clinical Immunology

Volumn 33, Issue SUPPL.1, 2013, Pages

  Lux, Anja ^a   Nimmerjahn, Falk ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Fc receptor; humanized mouse; immunoglobulin G; inflammation

Indexed keywords

CD16 ANTIGEN; CD64 ANTIGEN; CD64A ANTIGEN; FC GAMMA RECEPTOR IV; FC RECEPTOR; FC RECEPTOR IIA; FC RECEPTOR IIB; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; PHENYLALANINE; RITUXIMAB; TRASTUZUMAB; UNCLASSIFIED DRUG; VALINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIGEN ANTIBODY COMPLEX; AUTOIMMUNE DISEASE; BINDING AFFINITY; BREAST CANCER; EXPERIMENTAL MODEL; EXPERIMENTAL MOUSE; FCGAMMAR GENE; GENE; GENETIC VARIABILITY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN DEPOSITION; IMMUNOGLOBULIN STRUCTURE; IN VIVO STUDY; INNATE IMMUNITY; LYMPHOPROLIFERATIVE DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAG2 GENE; REVIEW; SEQUENCE HOMOLOGY; SEVERE COMBINED IMMUNODEFICIENCY;

ANIMALS; HUMANS; IMMUNOGLOBULIN G; MICE; MODELS, ANIMAL; RECEPTORS, IGG;

EID: 84872518803     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-012-9782-0     Document Type: Review

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