Phospholipases A2: Unveiling the secrets of a functionally versatile group of snake venom toxins

Toxicon

Volumn 62, Issue , 2013, Pages 27-39

  Gutiérrez, José María ^a   Lomonte, Bruno ^a  

^a UNIVERSIDAD DE COSTA RICA   (Costa Rica)

Author keywords

Enzymatic activity; Molecular evolution; Myotoxicity; Neurotoxicity; Phospholipase A2; Receptors; Snake venom; Toxicity

Indexed keywords

BETA BUNGAROTOXIN; BOTHROPSTOXIN I; CROTOXIN; METALLOPROTEINASE; MYOTOXIN; NOTEXIN; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLSERINE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 ISOZYME; PHOSPHOLIPASE A2 RECEPTOR; PHOSPHOLIPID; PHOSPHONIC ACID DERIVATIVE; SERINE PROTEINASE; SNAKE VENOM; UNCLASSIFIED DRUG; NEUROTOXIN; REPTILIAN PROTEIN;

AMINO ACID SEQUENCE; ANTICOAGULATION; BIOLOGICAL FUNCTIONS; CARBOXY TERMINAL SEQUENCE; CARDIOTOXICITY; CATALYSIS; CHEMICAL STRUCTURE; CRYSTALLIZATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; GENE; HEART MUSCLE FIBER MEMBRANE; HEMOLYSIS; LIPID HYDROLYSIS; MOLECULAR EVOLUTION; MOLECULAR WEIGHT; MUSCLE TOXICITY; NEUROTOXICITY; NONHUMAN; PHOSPHOLIPID DEGRADATION; PRESYNAPTIC NERVE; PRESYNAPTIC NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN TRANSPORT; REVIEW; STIMULUS SECRETION COUPLING; THROMBOCYTE FUNCTION; TOXICITY; CHEMISTRY; ENZYMOLOGY; ISOLATION AND PURIFICATION; PROTEIN TERTIARY STRUCTURE; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION;

EVOLUTION, MOLECULAR; MODELS, MOLECULAR; NEUROTOXINS; PHOSPHOLIPASES A2; PROTEIN STRUCTURE, TERTIARY; REPTILIAN PROTEINS; SEQUENCE ANALYSIS, PROTEIN; SNAKE VENOMS; STRUCTURE-ACTIVITY RELATIONSHIP;

MLCS; MLOWN;

EID: 84872502406     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2012.09.006     Document Type: Review

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