DNA repair gene variants are associated with an increased risk of myelodysplastic syndromes in a Czech population

Journal of Hematology and Oncology

Volumn 6, Issue 1, 2013, Pages

  Belickova, Monika ^a,b   Merkerova, Michaela Dostalova ^a   Stara, Eliska ^a   Vesela, Jitka ^a   Sponerova, Dana ^a   Mikulenkova, Dana ^a   Brdicka, Radim ^a   Neuwirtova, Radana ^b,c   Jonasova, Anna ^b,c   Cermak, Jaroslav ^a,b  

^a INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Association study; DNA repair; Myelodysplastic syndromes; SNP

Indexed keywords

AURORA A KINASE; CARRIER PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; ROS1 PROTEIN; SLC4A2 PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; CZECH REPUBLIC; DISEASE PREDISPOSITION; DNA REPAIR; DRUG RESPONSE; FEMALE; GENETIC ANALYSIS; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MYELODYSPLASTIC SYNDROME; OVERALL SURVIVAL; OXIDATIVE STRESS; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; CZECH REPUBLIC; DNA REPAIR; DNA REPAIR ENZYMES; DNA, NEOPLASM; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; RISK FACTORS; SURVIVAL RATE; YOUNG ADULT;

EID: 84872469877     PISSN: None     EISSN: 17568722     Source Type: Journal    
DOI: 10.1186/1756-8722-6-9     Document Type: Article

References (16)

1. Association between polymorphisms of folate-metabolizing enzymes and hematological malignancies. Kim HN, Kim YK, Lee IK, Yang DH, Lee JJ, Shin MH, Park KS, Choi JS, Park MR, Jo DY, Won JH, Kwak JY, Kim HJ, Leuk Res 2009 33 82 87 10.1016/j.leukres.2008.07.026 18774170
2. Genetic variant of the human homologous recombination-associated gene RMI1 (S455N) impacts the risk of AML/MDS and malignant melanoma. Broberg K, Höglund M, Gustafsson C, Björk J, Ingvar C, Albin M, Olsson H, Cancer Lett 2007 258 38 44 10.1016/j.canlet.2007.08.005 17900800 (Pubitemid 47600487)
3. Polymorphisms of detoxification and DNA repair enzymes in myelodyplastic syndromes. Fabiani E, D'Alò F, Scardocci A, Greco M, Di Ruscio A, Criscuolo M, Fianchi L, Pagano L, Hohaus S, Leone G, Voso MT, Leuk Res 2009 33 1068 1071 10.1016/j.leukres.2008.10.012 19027952
4. Significant association between polymorphism of the erythropoietin gene promoter and myelodysplastic syndrome. Ma W, Kantarjian H, Zhang K, Zhang X, Wang X, Chen C, Donahue AC, Zhang Z, Yeh CH, O'Brien S, Garcia-Manero G, Caporaso N, Landgren O, Albitar M, BMC Med Genet 2010 11 163 10.1186/1471-2350-11-163 21078205
5. Association between polymorphisms in RMI1, TOP3A, and BLM and risk of cancer, a case-control study. Broberg K, Huynh E, Schläwicke Engström K, Björk J, Albin M, Ingvar C, Olsson H, Höglund M, BMC Cancer 2009 9 140 10.1186/1471-2407-9-140 19432957
6. The 2008 revision of the WHO classification of myeloid neoplasms and acute leukemia: rationale and important changes. Vardiman JW, Thiele J, Arber DA, Brunning RD, Borowitz MJ, Porwit A, Harris NL, Le Beau MM, Hellström-Lindberg E, Tefferi A, Bloomfield CD, Blood 2009 114 937 951 10.1182/blood-2009-03-209262 19357394
7. Bladder cancer SNP panel predicts susceptibility and survival. Andrew AS, Gui J, Sanderson AC, Mason RA, Morlock EV, Schned AR, Kelsey KT, Marsit CJ, Moore JH, Karagas MR, Hum Genet 2009 125 527 539 10.1007/s00439-009-0645-6 19252927
8. Association of an MDR1 gene (C3435T) polymorphism with acute leukemia in India. Rao DN, Anuradha C, Vishnupriya S, Sailaja K, Surekha D, Raghunadharao D, Rajappa S, Asian Pac J Cancer Prev 2010 11 1063 1066 21133625
9. A case-control study of the association of the polymorphisms and haplotypes of DNA ligase I with lung and upper-aerodigestive-tract cancers. Lee YC, Morgenstern H, Greenland S, Tashkin DP, Papp J, Sinsheimer J, Cao W, Hashibe M, You NC, Mao JT, Cozen W, Mack TM, Zhang ZF, Int J Cancer 2008 122 1630 1638 18059021 (Pubitemid 351294974)
10. Genotype-phenotype relationship between DNA repair gene genetic polymorphisms and DNA repair capacity. Shin A, Lee KM, Ahn B, Park CG, Noh SK, Park DY, Ahn SH, Yoo KY, Kang D, Asian Pac J Cancer Prev 2008 9 501 505 18990028
11. Association between single-nucleotide polymorphisms in hormone metabolism and DNA repair genes and epithelial ovarian cancer: results from two Australian studies and an additional validation set. Beesley J, Jordan SJ, Spurdle AB, Song H, Ramus SJ, Kjaer SK, Hogdall E, DiCioccio RA, McGuire V, Whittemore AS, Gayther SA, Pharoah PD, Webb PM, Chenevix-Trench G, Australian Ovarian Cancer Study Group, Australian Cancer Study (Ovarian Cancer), Australian Breast Cancer Family Study, Cancer Epidemiol Biomarkers Prev 2007 16 2557 2565 10.1158/1055-9965.EPI-07-0542 18086758 (Pubitemid 351196309)
12. A distinct expression of various gene subsets in CD34+ cells from patients with early and advanced myelodysplastic syndrome. Vasikova A, Belickova M, Budinska E, Cermak J, Leuk Res 2010 34 1566 1572 10.1016/j.leukres.2010.02. 021 20303173
13. Aurora-A/STK15 T + 91A is a general low penetrance cancersusceptibility gene: a meta-analysis of multiple cancer types. Ewart-Toland A, Dai Q, Gao YT, Nagase H, Dunlop MG, Farrington SM, Barnetson RA, Anton-Culver H, Peel D, Ziogas A, Lin D, Miao X, Sun T, Ostrander EA, Stanford JL, Langlois M, Chan JM, Yuan J, Harris CC, Bowman ED, Clayman GL, Lippman SM, Lee JJ, Zheng W, Balmain A, Carcinogenesis 2005 26 1368 1373 10.1093/carcin/bgi085 15802297 (Pubitemid 41417879)
14. Functional analysis of the Aurora Kinase A Ile31 allelic variant in human prostate. Matarasso N, Bar-Shira A, Rozovski U, Rosner S, Orr-Urtreger A, Neoplasia 2007 9 707 715 10.1593/neo.07322 17898866 (Pubitemid 47523232)
15. Flt3 receptor inhibition reduces constitutive NFkappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia. Grosjean-Raillard J, Adès L, Boehrer S, Tailler M, Fabre C, Braun T, De Botton S, Israel A, Fenaux P, Kroemer G, Apoptosis 2008 13 1148 1161 10.1007/s10495-008-0243-4 18670883
16. Identification of a novel mechanism of NF-kappaB inactivation by progesterone through progesterone receptors in Hec50co poorly differentiated endometrial cancer cells: induction of A20 and ABIN-2. Davies S, Dai D, Feldman I, Pickett G, Leslie KK, Gynecol Oncol 2004 94 463 470 10.1016/j.ygyno.2004.05. 028 15297189 (Pubitemid 39024554)