Genotype-phenotype relationship between DNA repair gene genetic polymorphisms and DNA repair capacity

Asian Pacific Journal of Cancer Prevention

Volumn 9, Issue 3, 2008, Pages 501-505

  Shin, Aesun ^a   Lee, Kyoung Mu ^b   Ahn, Byungchan ^c   Park, Chung Gyu ^d   Park, Sue Kyung ^e   Noh, Dong Young ^f   Ahn, Sei Hyun ^g   Yoo, Keun Young ^e   Kang, Daehee ^e  

^a National Cancer Center   (South Korea)

^b NATIONAL CANCER INSTITUTE   (United States)

^c University of Ulsan   (South Korea)

^d Cancer Research Center   (South Korea)

^e Dept of Preventive Medicine ^*  (South Korea)

^f Seoul National University College of Medicine   (South Korea)

^g University of Ulsan College of Medicine   (South Korea)

Author keywords

Breast neoplasms; DNA repair; Genetic polymorphisms; Physiological influence

Indexed keywords

EID: 67650921928     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Ahn B, Kang D, Kim H, Wei Q (2004). Repair of mitomycin C cross-linked DNA in mammalian cells measured by a host cell reactivation assay. Molecules Cells, 18, 249-55.
2. Antoniou AC, Sinilnikova OM, Simard J, et al (2007). RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies. Am J Human Genetics, 81, 1186-200.
3. Bau DT, Mau YC, Ding SL, Wu PE, Shen CY (2007). DNA double-strand break repair capacity and risk of breast cancer. Carcinogenesis, 28, 1726-30.
4. Berwick M, Vineis P (2000). Markers of DNA repair and susceptibility to cancer in humans: an epidemiologic review. J Natl Cancer Inst, 92, 874-97.
5. Dasika GK, Lin SC, Zhao S, et al (1999). DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis. Oncogene, 18, 7883-99.
6. Dixon K, Kopras E (2004). Genetic alterations and DNA repair in human carcinogenesis. Sem Cancer Biol, 14, 441-8.
7. Hung RJ, Hall J, Brennan P, Boffetta P (2005). Genetic polymorphisms in the base excision repair pathway and cancer risk: a HuGE review. Am J Epidemiol, 162, 925-42.
8. Kennedy DO, Agrawal M, Shen J, et al (2005). DNA repair capacity of lymphoblastoid cell lines from sisters discordant for breast cancer. J Natl Cancer Inst, 97, 127-32.
9. Lee KM, Choi JY, Kang C, et al (2005a). Genetic polymorphisms of selected DNA repair genes, estrogen and progesterone receptor status, and breast cancer risk. Clin Cancer Res, 11, 4620-6.
10. Lee KM, Choi JY, Park SK, et al (2005b). Genetic polymorphisms of ataxia telangiectasia mutated and breast cancer risk. Cancer Epidemiol Biomarkers Prev, 14, 821-5.
11. Manuguerra M, Saletta F, Karagas MR, et al (2006). XRCC3 and XPD/ERCC2 single nucleotide polymorphisms and the risk of cancer: a HuGE review. Am J Epidemiol, 164, 297-302.
12. Muller-Vogt US, Maurer JE, Grabenbauer GG, et al (2003). Altered DNA repair capacity in young patients suffering from multiple cancers. Int J Molec Med, 11, 669-74.
13. Narod SA, Foulkes WD (2004). BRCA1 and BRCA2: 1994 and beyond. Nature Reviews, 4, 665-76.
14. Qiao Y, Spitz MR, Guo Z, et al (2002a). Rapid assessment of repair of ultraviolet DNA damage with a modified host-cell reactivation assay using a luciferase reporter gene and correlation with polymorphisms of DNA repair genes in normal human lymphocytes. Mutat Res, 509, 165-74.
15. Qiao Y, Spitz MR, Shen H, et al (2002b). Modulation of repair of ultraviolet damage in the host-cell reactivation assay by polymorphic XPC and XPD/ERCC2 genotypes. Carcinogenesis, 23, 295-9.
16. Shen J, Desai M, Agrawal M, et al (2006). Polymorphisms in nucleotide excision repair genes and DNA repair capacity phenotype in sisters discordant for breast cancer. Cancer Epidemiol Biomarkers Prev, 15, 1614-9.
17. Shi Q, Wang LE, Bondy ML, et al (2004). Reduced DNA repair of benzo[a]pyrene diol epoxide-induced adducts and common XPD polymorphisms in breast cancer patients. Carcinogenesis, 25, 1695-700.
18. Spitz MR, Wu X, Wang Y, et al (2001). Modulation of nucleotide excision repair capacity by XPD polymorphisms in lung cancer patients. Cancer Res, 61, 1354-7.
19. Stiff T, Walker SA, Cerosaletti K, et al (2006). ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling. EMBO J, 25, 5775-82.
20. Thacker J, (2005). The RAD51 gene family, genetic instability and cancer. Cancer Lett, 219, 125-35.
21. Venkitaraman AR, (2004). Tracing the network connecting BRCA and Fanconi anaemia proteins. Nature Reviews, 4, 266-76.
22. Wei Q, Matanoski GM, Farmer ER, Hedayati MA, Grossman L (1993). DNA repair and aging in basal cell carcinoma: a molecular epidemiology study. Proceedings of the National Academy of Sciences of the United States of America 90: 1614-8
23. Wood RD, Mitchell M, Sgouros J, Lindahl T (2001). Human DNA repair genes. Science, 291, 1284-9.
24. Wu X, Zhao H, Wei Q, et al (2003). XPA polymorphism associated with reduced lung cancer risk and a modulating effect on nucleotide excision repair capacity. Carcinogenesis, 24, 505-9.
25. Yasui A, McCready SJ (1998). Alternative repair pathways for UV-induced DNA damage. Bioessays, 20, 291-7.