Effect of desvenlafaxine on mood and climacteric symptoms in menopausal women with moderate to severe vasomotor symptoms

Climacteric

Volumn 16, Issue 1, 2012, Pages 17-27

  Cheng, R J ^a   Dupont, C ^b   Archer, D F ^c   Bao, W ^a   Racketa, J ^a   Constantine, G ^a   Pickar, J H ^a,d  

^a PFIZER INC   (United States)

^b DuPont Associates   (United States)

^c The Clinical Research Center   (United States)

^d NewYork Presbyterian Hospital   (United States)

Author keywords

Climacteric; Menopause; Mood Disturbance; Serotonin Norepinephrine Reuptake Inhibitor; Vasomotor Symptoms

Indexed keywords

DESVENLAFAXINE;

AMENORRHEA; ANGER; ANXIETY; AROUSAL; ARTICLE; BOTHERSOMENESS; CONFUSION; CONTROLLED STUDY; DEPRESSION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG TOLERABILITY; FATIGUE; FEMALE; FOLLITROPIN BLOOD LEVEL; HOSTILITY; HOT FLUSH; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MENOPAUSAL SYNDROME; MOOD DISORDER; MULTICENTER STUDY; OUTCOME ASSESSMENT; PAIN; PAIN ASSESSMENT; PATIENT SATISFACTION; POSTMENOPAUSE; PRIORITY JOURNAL; PROFILE OF MOOD STATES; RANDOMIZED CONTROLLED TRIAL; TENSION; VASOMOTOR DISORDER; VISUAL ANALOG SCALE;

EID: 84872451597     PISSN: 13697137     EISSN: 14730804     Source Type: Journal    
DOI: 10.3109/13697137.2012.672495     Document Type: Article

References (62)

1. National Institutes of Health. National Institutes of Health Stateof- the-Science Conference statement: management of menopauserelated symptoms. Ann Intern Med 2005;142: 1003-13
2. Freeman EW, Sherif K. Prevalence of hot flushes and night sweats around the world: a systematic review. Climacteric 2007;10: 197-214 (Pubitemid 46752443)
3. Utian WH. Psychosocial and socioeconomic burden of vasomotor symptoms in menopause: a comprehensive review. Health Qual Life Outcomes 2005;3: 47
4. Kravitz HM, Ganz PA, Bromberger J, et al. Sleep difficulty in women at midlife: a community survey of sleep and the menopausal transition. Menopause 2003;10: 19-28 (Pubitemid 36706318)
5. Ohayon MM. Severe hot flashes are associated with chronic insomnia. Arch Intern Med 2006;166: 1262-8 (Pubitemid 43967577)
6. Freedman RR, Roehrs TA. Effects of REM sleep and ambient temperature on hot flash-induced sleep disturbance. Menopause 2006;13: 576-83 (Pubitemid 44079528)
7. Bromberger JT, Assmann SF, Avis NE, et al. Persistent mood symptoms in a multiethnic community cohort of pre- and perimenopausal women. Am J Epidemiol 2003;158: 347-56 (Pubitemid 41288802)
8. Cohen LS, Soares CN, Vitonis AF, Otto MW, Harlow BL. Risk for new onset of depression during the menopausal transition: the Harvard study of moods and cycles. Arch Gen Psychiatry 2006;63: 385-90
9. Joffe H, Hall JE, Soares CN, et al. Vasomotor symptoms are associated with depression in perimenopausal women seeking primary care. Menopause 2002;9: 392-8 (Pubitemid 36706332)
10. Bosworth HB, Bastian LA, Kuchibhatla MN, et al. Depressive symptoms, menopausal status, and climacteric symptoms in women at midlife. Psychosom Med 2001;63: 603-8 (Pubitemid 32695141)
11. Dennerstein L, Dudley EC, Hopper JL, Guthrie JR, Burger HG. A prospective population-based study of menopausal symptoms. Obstet Gynecol 2000;96: 351-8
12. Avis NE, Brambilla D, McKinlay SM, Vass K. A longitudinal analysis of the association between menopause and depression. Results from the Massachusetts Women's Health Study. Ann Epidemiol 1994;4: 214-20 (Pubitemid 24154300)
13. MacLennan AH, Broadbent JL, Lester S, Moore V. Oral oestrogen and combined oestrogen/progestogen therapy versus placebo for hot flushes. Cochrane Database Syst Rev 2004;CD002978
14. Schmidt PJ, Nieman L, Danaceau MA, et al. Estrogen replacement in perimenopause-related depression: a preliminary report. Am J Obstet Gynecol 2000;183: 414-20 (Pubitemid 30651090)
15. Soares CN, Almeida OP, Joffe H, Cohen LS. Efficacy of estradiol for the treatment of depressive disorders in perimenopausal women: a double-blind, randomized, placebo-controlled trial. Arch Gen Psychiatry 2001;58: 529-34 (Pubitemid 32523731)
16. Morrison MF, Kallan MJ, Ten HT, et al. Lack of efficacy of estradiol for depression in postmenopausal women: a randomized, controlled trial. Biol Psychiatry 2004;55: 406-12 (Pubitemid 38199991)
17. Zweifel JE, O'Brien WH. A meta-analysis of the effect of hormone replacement therapy upon depressed mood. Psychoneuroendocrinology 1997;22: 189-212 (Pubitemid 27293623)
18. McEwen B. Estrogen actions throughout the brain. Recent Prog Horm Res 2002;57: 357-84
19. Delgado PL. Common pathways of depression and pain. J Clin Psychiatry 2004;65: 16-19
20. Soares CN, Arsenio H, Joffe H, et al. Escitalopram versus ethinyl estradiol and norethindrone acetate for symptomatic peri- and postmenopausal women: impact on depression, vasomotor symptoms, sleep, and quality of life. Menopause 2006;13: 780-6 (Pubitemid 44435032)
21. Loprinzi CL, Flynn PJ, Carpenter LA, et al. Pilot evaluation of citalopram for the treatment of hot flashes in women with inadequate benefit from venlafaxine. J Palliat Med 2005;8: 924-30 (Pubitemid 41579234)
22. Barton DL, Loprinzi CL, Novotny P, et al. Pilot evaluation of citalopram for the relief of hot flashes. J Support Oncol 2003; 1: 47-51
23. Stearns V, Isaacs C, Rowland J, et al. A pilot trial assessing the efficacy of paroxetine hydrochloride (Paxil) in controlling hot flashes in breast cancer survivors. Ann Oncol 2000;11: 17-22 (Pubitemid 30084574)
24. Weitzner MA, Moncello J, Jacobsen PB, Minton S. A pilot trial of paroxetine for the treatment of hot flashes and associated symptoms in women with breast cancer. J Pain Symptom Manage 2002;23: 337-45 (Pubitemid 34462946)
25. Biglia N, Torta R, Roagna R, et al. Evaluation of low-dose venlafaxine hydrochloride for the therapy of hot flushes in breast cancer survivors. Maturitas 2005;52: 78-85 (Pubitemid 41242746)
26. Pristiq [package insert]. Philadelphia, PA: Wyeth Pharmaceuticals Inc., a subsidiary of Pfizer, 2011.
27. Archer DF, Seidman L, Constantine GD, et al. A double-blind, randomly assigned, placebo-controlled study of desvenlafaxine efficacy and safety for the treatment of vasomotor symptoms associated with menopause. Am J Obstet Gynecol 2009;200: 172.e1-10
28. Speroff L, Gass M, Constantine G, Olivier S, for the Study 315 investigators. Efficacy and tolerability of desvenlafaxine succinate treatment for menopausal vasomotor symptoms: a randomized controlled trial. Obstet Gynecol 2008;111: 77-87
29. Archer DF, Dupont CM, Constantine GD, et al. Desvenlafaxine for the treatment of vasomotor symptoms associated with menopause: a double-blind, randomized, placebo-controlled trial of efficacy and safety. Am J Obstet Gynecol 2009;200: 238.e1-10
30. Miller KJ, Conney JC, Rasgon NL, Fairbanks LA, Small GW. Mood symptoms and cognitive performance in women estrogen users and nonusers and men. J Am Geriatr Soc 2002;50: 1826-30 (Pubitemid 35291726)
31. Cummings JA, Brizendine L. Comparison of physical and emotional side effects of progesterone or medroxyprogesterone in early postmenopausal women. Menopause 2002;9: 253-63 (Pubitemid 34743450)
32. Boyle GJ, Murrihy R. A preliminary study of hormone replacement therapy and psychological mood states in perimenopausal women. Psychol Rep 2001;88: 160-70 (Pubitemid 33600405)
33. Slaven L, Lee C. Mood and symptom reporting among middleaged women: the relationship between menopausal status, hormone replacement therapy, and exercise participation. Health Psychol 1997;16: 203-8 (Pubitemid 127465957)
34. Greene JG. Constructing a standard climacteric scale. Maturitas 1998;29: 25-31 (Pubitemid 28247565)
35. Hill CD, Fehnel SE, Bobula JD, Yu H, McLeod LD. Development and preliminary validation of the Menopause Symptoms Treatment Satisfaction Questionnaire (MS-TSQ). Menopause 2007;14: 1047-55 (Pubitemid 350098665)
36. DeLoach LJ, Higgins MS, Caplan AB, Stiff JL. The visual analog scale in the immediate postoperative period: intrasubject variability and correlation with a numeric scale. Anesth Analg 1998;86: 102-6 (Pubitemid 28040099)
37. Avis NE, Crawford S, Stellato R, Longcope C. Longitudinal study of hormone levels and depression among women transitioning through menopause. Climacteric 2001;4: 243-9 (Pubitemid 32896914)
38. Freeman EW, Sammel MD, Lin H, Nelson DB. Associations of hormones and menopausal status with depressed mood in women with no history of depression. Arch Gen Psychiatry 2006;63: 375-82
39. Liebowitz MR, Manley AL, Padmanabhan SK, et al. Efficacy, safety, and tolerability of desvenlafaxine 50 mg/day and 100 mg/day in outpatients with major depressive disorder. Curr Med Res Opin 2008;24: 1877-90
40. Magliano M. Menopausal arthralgia: fact or fiction. Maturitas 2010;67: 29-33
41. Freeman MP, Hill R, Brumbach BH. Escitalopram for perimenopausal depression: an open-label pilot study. J Womens Health (Larchmt) 2006;15: 857-61 (Pubitemid 46381704)
42. Ladd CO, Newport DJ, Ragan KA, Loughhead A, Stowe ZN. Venlafaxine in the treatment of depressive and vasomotor symptoms in women with perimenopausal depression. Depress Anxiety 2005;22: 94-7 (Pubitemid 41598045)
43. Cohen LS, Soares CN, Poitras JR, et al. Short-term use of estradiol for depression in perimenopausal and postmenopausal women: a preliminary report. Am J Psychiatry 2003;160: 1519-22 (Pubitemid 41070931)
44. Soares CN, Prouty J, Born L, Steiner M. Treatment of menopauserelated mood disturbances. CNS Spectr 2005;10: 489-97
45. Baber RJ, Templeman C, Morton T, Kelly GE, West L. Randomized placebo-controlled trial of an isoflavone supplement and menopausal symptoms in women. Climacteric 1999;2: 85-92 (Pubitemid 29333647)
46. Knight DC, Howes JB, Eden JA. The effect of Promensil, an isoflavone extract, on menopausal symptoms. Climacteric 1999; 2: 79-84 (Pubitemid 29333646)
47. van de Weijer PHM, Barentsen R. Isoflavones from red clover (Promensil®) significantly reduce menopausal hot flush symptoms compared with placebo. Maturitas 2002;42: 187-93 (Pubitemid 34876810)
48. Tice JA, Ettinger B, Ensrud K, et al. Phytoestrogen supplements for the treatment of hot flashes: the Isoflavone Clover Extract (ICE) Study: a randomized controlled trial. JAMA 2003;290: 207-14 (Pubitemid 37430059)
49. Secreto G, Chiechi LM, Amadori A, et al. Soy isoflavones and melatonin for the relief of climacteric symptoms: a multicenter, double-blind, randomized study. Maturitas 2004;47: 11-20 (Pubitemid 38050011)
50. Duffy R, Wiseman H, File SE. Improved cognitive function in postmenopausal women after 12 weeks of consumption of a soya extract containing isoflavones. Pharmacol Biochem Behav 2003; 75: 721-9 (Pubitemid 36936904)
51. Verhoeven MO, van der Mooren MJ, van de Weijer PHM, et al. Effect of a combination of isoflavones and Actaea racemosa Linnaeus on climacteric symptoms in healthy symptomatic perimenopausal women: a 12-week randomized, placebo-controlled, double-blind study. Menopause 2005;12: 412-20 (Pubitemid 41098654)
52. Geller SE, Shulman LP, van Breemen RB, et al. Safety and efficacy of black cohosh and red clover for the management of vasomotor symptoms: a randomized controlled trial. Menopause 2009;16: 1156-66
53. Lontos S, Jones RM, Angus PW, Gow PJ. Acute liver failure associated with the use of herbal preparations containing black cohosh. Med J Aust 2003;179: 390-1 (Pubitemid 37265139)
54. Lynch CR, Folkers ME, Hutson WR. Fulminant hepatic failure associated with the use of black cohosh: a case report. Liver Transpl 2006;12: 989-92 (Pubitemid 43960376)
55. Cagnacci A, Arangino S, Renzi A, et al. Kava-Kava administration reduces anxiety in perimenopausal women. Maturitas 2003;44: 103-9 (Pubitemid 36173967)
56. Biglia N, Sgandurra P, Peano E, et al. Non-hormonal treatment of hot flushes in breast cancer survivors: gabapentin vs. vitamin E. Climacteric 2009;12: 310-18
57. Reddy SY, Warner H, Guttuso T Jr, et al. Gabapentin, estrogen, and placebo for treating hot flushes: a randomized controlled trial. Obstet Gynecol 2006;108: 41-8 (Pubitemid 44336843)
58. Guttuso T, Kurlan R, McDermott MP, Kieburtz K. Gabapentin's effects on hot flashes in postmenopausal women: a randomized controlled trial. Obstet Gynecol 2003;101: 337-45 (Pubitemid 36170136)
59. Salmi T, Punnonen R. Clonidine in the treatment of menopausal symptoms. Int J Gynaecol Obstet 1979;16: 422-6 (Pubitemid 9149988)
60. Wren BG, Brown LB. A double-blind trial with clonidine and a placebo to treat hot flushes. Med J Aust 1986;144: 369-70 (Pubitemid 16069540)
61. Pandya KJ, Raubertas RF, Flynn PJ, et al. Oral clonidine in postmenopausal patients with breast cancer experiencing tamoxifeninduced hot flashes: a University of Rochester Cancer Center Community Clinical Oncology Program study. Ann Intern Med 2000;132: 788-93 (Pubitemid 30317793)
62. Kornstein SG, Jiang Q, Reddy S, Musgnung JJ, Guico-Pabia CJ. Short-term efficacy and safety of desvenlafaxine in a randomized, placebo-controlled study of perimenopausal and postmenopausal women with major depressive disorder. J Clin Psychiatry 2010;71: 1088-96