Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency

Journal of Cell Science

Volumn 125, Issue 24, 2012, Pages 6094-6104

  Paque, Vincent ^a,b,c   Radzisheuskaya, Aliaksandra ^b   Gillich, Astrid ^a,b   Halley Stott, Richard P ^a,b   Panamarova, Maryna ^a,b   Zernicka Goetz, Magdalena ^a,b   Surani, M Azim ^a,b   Silva, José C R ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cell commitment; Epigenetic stability; Induced pluripotency; MacroH2A; Nuclear reprogramming

Indexed keywords

HISTONE VARIANT MACROH2A; NUCLEAR PROTEIN; UNCLASSIFIED DRUG; HISTONE; MACROH2A HISTONE;

ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CELL FATE; CHROMATIN IMMUNOPRECIPITATION; ECTODERM; EMBRYO DEVELOPMENT; EPIGENETICS; FIBROBLAST; GENE OVEREXPRESSION; GENE SILENCING; IN VIVO STUDY; MOUSE; NEURAL STEM CELL; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SOMATIC CELL; TRANSGENE; ANIMAL; C57BL MOUSE; CBA MOUSE; CYTOLOGY; EMBRYONIC STEM CELL; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; MALE; METABOLISM; NUCLEAR REPROGRAMMING; PHYSIOLOGY;

ANIMALS; CELL DIFFERENTIATION; CELLULAR REPROGRAMMING; EMBRYONIC STEM CELLS; EPIGENOMICS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HISTONES; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; PLURIPOTENT STEM CELLS; TRANSFECTION;

EID: 84872442222     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.113019     Document Type: Article

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