PhoB Regulates the Survival of Bacteroides fragilis in Peritoneal Abscesses

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Wakimoto, Shin ^a   Nakayama Imaohji, Haruyuki ^b   Ichimura, Minoru ^a,b   Morita, Hidetoshi ^c   Hirakawa, Hideki ^d   Hayashi, Tetsuya ^e   Yasutomo, Koji ^a   Kuwahara, Tomomi ^b  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b KAGAWA UNIVERSITY   (Japan)

^c AZABU UNIVERSITY   (Japan)

^d KAZUSA DNA RESEARCH INSTITUTE   (Japan)

^e UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL POLYSACCHARIDE; BACTERIAL PROTEIN; CHAPERONE; HEAT SHOCK PROTEIN; PHOSPHATE; PROTEIN HISTIDINE KINASE; PROTEIN PHOB; PROTEIN PHOR; UNCLASSIFIED DRUG;

ABSCESS; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; BACTEROIDES FRAGILIS; CELL STRESS; CONTROLLED STUDY; CULTURE MEDIUM; DNA MICROARRAY; GEL MOBILITY SHIFT ASSAY; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; HOST PATHOGEN INTERACTION; IN VITRO STUDY; IN VIVO STUDY; INTESTINE FLORA; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PERITONEUM ABSCESS; PERITONITIS; PHOSPHATE METABOLISM; REGULON; TRANSCRIPTOMICS;

ABDOMINAL ABSCESS; ANIMALS; BACTERIAL PROTEINS; BACTEROIDES FRAGILIS; BACTEROIDES INFECTIONS; MALE; MICE; MICE, INBRED C57BL; MICROBIAL VIABILITY; PERITONEUM; PROTEIN KINASES; REGULON; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL;

BACTERIA (MICROORGANISMS); BACTEROIDES FRAGILIS;

EID: 84872411415     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053829     Document Type: Article

References (39)

1. Marijuan PC, Navarro J, del Moral R, (2010) On prokaryotic intelligence: Strategies for sensing the environment. Biosystems 99: 94-103.
2. Wanner BL (1996) Phosphate assimilation and control of the phosphate regulon. In: Neidhardt FC, Curtiss R III, Ingraham JL, Lin ECC, Low KB, et al. editors. Escherichia coli and Salmonella: Cellular and Molecular Biology, 2nd ed. vol. 1. Washington DC: ASM Press. 1357-1381.
3. Lamarche MG, Wanner BL, Creoin S, Harel J, (2008) The phosphate regulon and bacterial virulence: a regulatory network connecting phosphate homeostasis and pathogenesis. FEMS Microbiol Rev 32: 461-473.
4. Chatterjee SS, Hossain H, Otten S, Kuenne C, Kuchmina K, et al. (2006) Intracellular gene expression profile of Listeria monocytogenes. Infect Immun 74: 1323-1338.
5. Dubail I, Berche P, Charbit A, (2000) Listriolysin O as a reporter to identify constitutive and in vivo-inducible promoters in the pathogen Listeria monocytogenes. Infect Immun 68: 3242-3250.
6. Grabenstein JP, Fukuto HS, Palmer LE, Bliska JB, (2006) Characterization of phagosome trafficking and identification of PhoP-regulated genes important for survival of Yersinia pestis in macrophages. Infect Immun 74: 3727-3741.
7. Talaat AM, Lyons R, Howard ST, Johnston SA, (2004) The temporal expression profile of Mycobacterium tuberculosis in mice. Proc Natl Acad Sci U S A 101: 4602-4607.
8. Yang S, Perna NT, Cooksey DA, Okinaka Y, Lindow SE, et al. (2004) Genome-wide identification of plant-upregulated genes of Erwinia chrysanthemi 3937 using a GFP-based IVET leaf array. Mol Plant Microbe Interact 17: 999-1008.
9. Costello EK, Lauber CL, Hamady M, Fierer N, Gordon JI, et al. (2009) Bacterial community variation in human body habitats across space and time. Science 326: 1694-1697.
10. Dethlefsen L, MacFall-Ngai M, Relman DA, (2007) An ecological and evolutionary perspective on human-microbe mutualism and disease. Nature 449: 811-818.
11. Alverdy J, Holbrook C, Rocha F, Seiden L, Licheng W, et al. (2000) Gut-derived sepsis occurs when the right pathogen with the right virulence genes meets the right host. Ann Surg 232: 480-489.
12. Long J, Zaborina O, Holbrook C, Zaborin A, Alverdy J, (2008) Depletion of intestinal phosphate after operative injury activates the virulence of P. aeruginosa causing lethal gut-derived sepsis. Surgery 144: 189-197.
13. Wu LR, Zoborina O, Zaborin A, Chang EB, Musch M, et al. (2005) Operative injury and metabolic stress enhance the virulence of the human opportunistic pathogen Pseudomonas aeruginosa. Surg Infect (Larchmt) 6: 185-195.
14. Coyne MJ, Tzianabos AO, Mallory BC, Carey VJ, Kasper DL, et al. (2001) Polysaccharide biosynthesis locus required for virulence of Bacteroides fragilis. Infect Immun 69: 4342-4350.
15. Coyne MJ, Kalka-Moll W, Tzianabos AO, Kasper DL, Comstock LE, (2000) Bacteroides fragilis NCTC9343 produces at least three distinct capsular polysaccharides: cloning, characterization, and reassignment of polysaccharide B and C biosynthesis loci. Infect Immun 68: 6176-6181.
16. Wexler HM, (2007) Bacteroides: the good, the bad, and the nitty-gritty. Clin Microbiol Rev 20: 593-621.
17. Varel VH, Bryant MP, (1974) Nutritional features of Bacteroides fragilis subsp. fragilis. Appl. Microbiol. 18: 251-257.
18. Ichimura M, Nakayama-Imaohji H, Wakimoto S, Morita H, Hayashi T, et al. (2010) Efficient electrotransformation of Bacteroides fragilis. Appl Environ Microbiol 76: 3325-3332.
19. Nakayama-Imaohji H, Hirakawa H, Ichimura M, Wakimoto S, Kuhara S, et al. (2009) Identification of the site-specific DNA invertase responsible for the phase variation of SusC/SusD family outer membrane proteins in Bacteroides fragilis. J Bacteriol 191: 6003-6011.
20. Rocha ER, Smith CJ, (1997) Regulation of Bacteriodes fragilis katB mRNA by oxidative stress and carbon limitation. J Bacteriol 179: 7033-7039.
21. Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Method 25: 402-408.
22. Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, et al. (2003) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4: 249-264.
23. Elson CO, Cong Y, McCracken VJ, Dimmitt RA, Lorenz RG, et al. (2005) Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota. Immunol Rev 206: 260-276.
24. Sartor RB, (2008) Microbial influences in inflammatory bowel diseases. Gastroenterol 134: 577-594.
25. Chu FF, Esworthy RS, Chu PG, Longmate JA, Huycke MM, et al. (2004) Bacteria-induced intestinal cancer in mice with disrupted gpx1 and gpx2 genes. Cancer Res 64: 962-968.
26. Ley RE, Backhed F, Turnbauch P, Lozupone CA, Knight RD, (2005) Obesity alters gut microbial ecology. Proc Natl Acad Sci U S A 102: 11070-11075.
27. Ley RE, Turnbauch PJ, Klein S, Gordon JI, (2006) Microbial ecology: human gut microbes associated with obesity. Nature 444: 1022-1023.
28. Turnbaugh PJ, Hamady M, Yatsunenko T, Cantarel BL, Duncan A, et al. (2009) A core gut microbiome in obese and lean twins. Nature 457: 480-484.
29. Turnbaugh PJ, Ley RE, Mahowald MA, Magrini V, Mardis ER, et al. (2006) An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 444: 1027-1031.
30. Hajishengallis C, Darveau RP, Curtis MA, (2012) The keystone-pathogen hypothesis. Nat Rev Microbiol 10: 717-725.
31. Kuwahara T, Yamashita A, Hirakawa H, Nakayama H, Toh H, et al. (2004) Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation. Proc Natl Acad Sci U S A 101: 14919-14924.
32. Krinos CM, Coyne MJ, Weinacht KG, Tzianabos AO, Kasper DL, et al. (2001) Extensive surface diversity of a commensal microorganism by multiple DNA inversions. Nature 414: 555-558.
33. Chatzidaki-Livanis M, Weinacht KG, Comstock LE, (2010) Trans locus inhibitors limit concomitant polysaccharide synthesis in the human gut symbiont Bacteroides fragilis. Proc Natl Acad Sci U S A 101: 14919-14924.
34. Patrick S, Blakely GW, Houston S, Moore J, Abratt VR, et al. (2010) Twenty-eight divergent polysaccharide loci specifying within- and amongst-strain capsule diversity in three strains of Bacteroides fragilis. Microbiol 156 (Pt11): 3255-69.
35. Patt JT, Ismail AM, Camilli A, (2010) PhoB regulates both environmental and virulence gene expression in Vibrio cholerae. Mol Microbiol 77: 1595-1605.
36. Bertrand N, Houle S, LeBihan G, Poirier E, Dozois CM, et al. (2010) Increased Pho regulon activation correlates with decreased virulence of an avian pathogenic Escherichia coli O78 strain. Infect Immun 78: 5324-5331.
37. Kuwahara T, Sarker MR, Ugai H, Akimoto S, Shaheduzzaman SM, et al. (2002) Physical and genetic map of the Bacteroides fragilis YCH46 chromosome. FEMS Microbiol Lett 207: 193-197.
38. Salyers AA, Shoemaker NB, Cooper A, D'Elia J, Shipman JA, (1999) Genetic methods for Bacteroides species. Methods Microbiol 29: 229-276.
39. Bayley DP, Rocha ER, Smith CJ, (2000) Analysis of cepA and other Bacteroides fragilis genes reveals a unique promoter structure. FEMS Microbiol Lett 193: 149-154.