Therapeutic hypothermia for cardiac arrest: Real-world utilization trends and hospital mortality

Journal of Hospital Medicine

Volumn 7, Issue 9, 2012, Pages 684-689

  Jena, Anupam B ^a,b,c   Romley, John A ^d   Newton Cheh, Christopher ^b   Noseworthy, Peter ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c NATIONAL BUREAU OF ECONOMIC RESEARCH   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN HYPOXIA; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; FEMALE; HEALTH CARE UTILIZATION; HEART ARREST; HOSPITAL BILLING; HOSPITAL DISCHARGE; HUMAN; INDUCED HYPOTHERMIA; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TREND STUDY;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CALIFORNIA; COMORBIDITY; FEMALE; HEART ARREST; HOSPITAL MORTALITY; HUMANS; HYPOTHERMIA, INDUCED; HYPOXIA, BRAIN; MALE; MIDDLE AGED; ODDS RATIO; RETROSPECTIVE STUDIES; SEX FACTORS;

EID: 84872393328     PISSN: 15535592     EISSN: 15535606     Source Type: Journal    
DOI: 10.1002/jhm.1974     Document Type: Article

References (31)

1. Zheng ZJ, Croft JB, Giles WH, et al. Sudden cardiac death in the United States, 1989 to 1998. Circulation. 2001; 104( 18): 2158-2163.
2. Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006; 3( 11): e442.
3. Bernard SA, Gray TW, Buist MD, et al. Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med. 2002; 346( 8): 557-563.
4. Hypothermia After Cardiac Arrest Study Group. Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med. 2002; 346( 8): 549-556.
5. Nolan JP, Morley PT, Vanden Hoek TL, et al. Therapeutic hypothermia after cardiac arrest: an advisory statement by the Advanced Life Support Task Force of the International Liaison Committee on Resuscitation. Circulation. 2003; 108( 1): 118-121.
6. 2005 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care: part 7.5: postresuscitation support. Circulation. 2005; 112(suppl I): IV-84-IV-88.
7. Deakin CD, Morrison LJ, Morley PT, et al. Part 8: advanced life support: 2010 international consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations. Resuscitation. 2010; 81(suppl 1): e93-e174.
8. Abella BS, Rhee JW, Huang KN, et al. Induced hypothermia is underused after resuscitation from cardiac arrest: a current practice survey. Resuscitation. 2005; 64( 2): 181-186.
9. Merchant RM, Soar J, Skrifvars MB, et al. Therapeutic hypothermia utilization among physicians after resuscitation from cardiac arrest. Crit Care Med. 2006; 34( 7): 1935-1940.
10. Nielsen N, Sunde K, Hovdenes J, et al. Adverse events and their relation to mortality in out-of-hospital cardiac arrest patients treated with therapeutic hypothermia. Crit Care Med. 39( 1): 57-64.
11. Nielsen N, Hovdenes J, Nilsson F, et al. Outcome, timing and adverse events in therapeutic hypothermia after out-of-hospital cardiac arrest. Acta Anaesthesiol Scand. 2009; 53( 7): 926-934.
12. Arrich J. Clinical application of mild therapeutic hypothermia after cardiac arrest. Crit Care Med. 2007; 35( 4): 1041-1047.
13. Mooney MR, Unger BT, Boland LL, et al. Therapeutic hypothermia after out-of-hospital cardiac arrest: evaluation of a regional system to increase access to cooling. Circulation. 2011; 124( 2): 206-214.
14. American Hospital Association (AHA). American Hospital Association 2001 Annual Survey. Chicago, IL: Health Forum, LLC.
15. Austin PC, Daly PA, Tu JV. A multicenter study of the coding accuracy of hospital discharge administrative data for patients admitted to cardiac care units in Ontario. Am Heart J. 2002; 144( 2): 290-296.
16. Goldstein LB. Accuracy of ICD-9-CM coding for the identification of patients with acute ischemic stroke: effect of modifier codes. Stroke. 1998; 29( 8): 1602-1604.
17. Holzer M. Targeted temperature management for comatose survivors of cardiac arrest. N Engl J Med. 2010; 363( 13): 1256-1264.
18. Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987; 40( 5): 373-383.
19. Deyo RA, Cherkin DC, Ciol MA. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol. 1992; 45( 6): 613-619.
20. Romano PS, Roos LL, Jollis JG. Adapting a clinical comorbidity index for use with ICD-9-CM administrative data: differing perspectives. J Clin Epidemiol. 1993; 46( 10): 1075-1079; discussion 1081-1090.
21. Gaieski DF, Fuchs B, Carr BG, et al. Practical implementation of therapeutic hypothermia after cardiac arrest. Hosp Pract (Minneap). 2009; 37( 1): 71-83.
22. Zraick K. Paramedics will employ new therapy in cardiac arrest cases. New York Times. August 3, 2010: A18.
23. Mechem CC, Goodloe JM, Richmond NJ, et al. Resuscitation center designation: recommendations for emergency medical services practices. Prehosp Emerg Care. 2010; 14( 1): 51-61.
24. Szumita PM, Baroletti S, Avery KR, et al. Implementation of a hospital-wide protocol for induced hypothermia following successfully resuscitated cardiac arrest. Crit Pathw Cardiol. 2010; 9( 4): 216-220.
25. Kulstad CE, Holt SC, Abrahamsen AA, et al. Therapeutic hypothermia protocol in a community emergency department. West J Emerg Med. 2010; 11( 4): 367-372.
26. Walters EL, Morawski K, Dorotta I, et al. Implementation of a post-cardiac arrest care bundle including therapeutic hypothermia and hemodynamic optimization in comatose patients with return of spontaneous circulation after out-of-hospital cardiac arrest: a feasibility study. Shock. 2011; 35( 4): 360-366.
27. Hinchey PR, Myers JB, Lewis R, et al. Improved out-of-hospital cardiac arrest survival after the sequential implementation of 2005 AHA guidelines for compressions, ventilations, and induced hypothermia: the Wake County experience. Ann Emerg Med. 2010; 56( 4): 348-357.
28. Prior J, Lawhon-Triano M, Fedor D, et al. Community-based application of mild therapeutic hypothermia for survivors of cardiac arrest. South Med J. 2010; 103( 4): 295-300.
29. Arrich J, Holzer M, Herkner H, et al. Hypothermia for neuroprotection in adults after cardiopulmonary resuscitation. Cochrane Database Syst Rev 2009( 4): CD004128.
30. Holzer M, Behringer W. Therapeutic hypothermia after cardiac arrest and myocardial infarction. Best Pract Res Clin Anaesthesiol. 2008; 22( 4): 711-728.
31. Merchant RM, Becker LB, Abella BS, et al. Cost-effectiveness of therapeutic hypothermia after cardiac arrest. Circ Cardiovasc Qual Outcomes. 2009; 2( 5): 421-428.