Chronic exposure of neonatal rat adrenomedullary chromaffin cells to opioids in vitro blunts both hypoxia and hypercapnia chemosensitivity

Journal of Physiology

Volumn 591, Issue 2, 2013, Pages 515-529

  Salman, Shaima ^a   Buttigieg, Josef ^b   Zhang, Min ^a   Nurse, Colin A ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF REGINA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CARBON DIOXIDE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CATECHOLAMINE; DELTA OPIATE RECEPTOR; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; GLIBENCLAMIDE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; NALOXONE; NICOTINIC AGENT; OPIATE; OXYGEN; POTASSIUM ION; SPIRADOLINE; TYROSYL DEXTRO ARGINYLPHENYLALANYLLYSINAMIDE;

ANIMAL CELL; AROUSAL; ARTICLE; CATECHOLAMINE RELEASE; CELL MEMBRANE DEPOLARIZATION; CHANNEL GATING; CHEMOSENSITIVITY; CHROMAFFIN CELL; CONTROLLED STUDY; DOWN REGULATION; HYPERCAPNIA; HYPOXIA; IN VITRO STUDY; INCUBATION TIME; NEWBORN; NONHUMAN; POTASSIUM CURRENT; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SPLANCHNIC NERVE; UPREGULATION;

ACTION POTENTIALS; ADRENAL GLANDS; ANALGESICS, OPIOID; ANIMALS; CARBON DIOXIDE; CARBONIC ANHYDRASES; CELL HYPOXIA; CELLS, CULTURED; CHROMAFFIN CELLS; GENE EXPRESSION; GLYBURIDE; KATP CHANNELS; NALOXONE; NARCOTIC ANTAGONISTS; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RATS; RATS, WISTAR; RECEPTORS, OPIOID; SPLANCHNIC NERVES;

EID: 84872392014     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2012.243477     Document Type: Article

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