Primary open-angle glaucoma vs normal-tension glaucoma: The vascular perspective

Archives of Ophthalmology

Volumn 131, Issue 1, 2013, Pages 36-43

  Mroczkowska, Stephanie ^a   Benavente Perez, Alexandra ^a   Negi, Anil ^b   Sung, Velota ^c   Patel, Sunni R ^a   Gherghel, Doina ^a  

^a ASTON UNIVERSITY   (United Kingdom)

^b UNIVERSITY HOSPITALS BIRMINGHAM NHS FOUNDATION TRUST   (United Kingdom)

^c CITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTERIAL STIFFNESS; ARTERIAL WALL THICKNESS; ARTICLE; BLOOD PRESSURE MONITORING; BLOOD VESSEL REACTIVITY; FEMALE; HUMAN; LOW TENSION GLAUCOMA; MAJOR CLINICAL STUDY; MALE; OPEN ANGLE GLAUCOMA; PRIORITY JOURNAL; PULSE WAVE; BLOOD FLOW VELOCITY; BLOOD PRESSURE; BODY CONSTITUTION; CIRCULATION; COMPARATIVE STUDY; INTRAOCULAR PRESSURE; LIGHT; MIDDLE AGED; OCULOPLETHYSMOGRAPHY; PATHOPHYSIOLOGY; PHYSIOLOGY; RADIATION EXPOSURE; RETINA BLOOD VESSEL; ADULT; BLOOD PRESSURE VARIABILITY; BLOOD VESSEL FUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE COURSE;

AGED; BLOOD CIRCULATION; BLOOD FLOW VELOCITY; BLOOD PRESSURE; BLOOD PRESSURE MONITORING, AMBULATORY; BODY CONSTITUTION; CAROTID INTIMA-MEDIA THICKNESS; FEMALE; GLAUCOMA, OPEN-ANGLE; HUMANS; INTRAOCULAR PRESSURE; LIGHT; LOW TENSION GLAUCOMA; MALE; MIDDLE AGED; RETINAL VESSELS; TONOMETRY, OCULAR;

MLCS; MLOWN;

EID: 84872362313     PISSN: 00039950     EISSN: 15383601     Source Type: Journal    
DOI: 10.1001/2013.jamaophthalmol.1     Document Type: Article

References (84)

1. Leydhecker W, ed. Glaucoma Symposium: Tutzing Castle, August 5-10, 1966. New York, NY: S Karger; 1967.
2. Hollows FC, Graham PA. Intra-ocular pressure, glaucoma, and glaucoma suspects in a defined population. Br J Ophthalmol. 1966;50(10):570-586.
3. Feke GT, Pasquale LR. Retinal blood flow response to posture change in glaucoma patients compared with healthy subjects. Ophthalmology. 2008;115(2):246-252. (Pubitemid 351163367)
4. Pemp B, Georgopoulos M, Vass C, et al. Diurnal fluctuation of ocular blood flow parameters in patients with primary open-angle glaucoma and healthy subjects. Br J Ophthalmol. 2009;93(4):486-491.
5. Garhöfer G, Zawinka C, Resch H, Huemer KH, Schmetterer L, Dorner GT. Response of retinal vessel diameters to flicker stimulation in patients with early open angle glaucoma. J Glaucoma. 2004;13(4):340-344. (Pubitemid 38944204)
6. Su W-W, Cheng S-T, Ho W-J, Tsay P-K, Wu S-C, Chang SHL. Glaucoma is associated with peripheral vascular endothelial dysfunction. Ophthalmology. 2008;115(7):1173-1178, e1.
7. Gherghel D, Hosking SL, Armstrong R, Cunliffe IA. Autonomic dysfunction in unselected and untreated primary open angle glaucoma patients: a pilot study. Ophthalmic Physiol Opt. 2007;27(4):336-341. (Pubitemid 46955423)
8. Gherghel D, Orgül S, Gugleta K, Gekkieva M, Flammer J. Relationship between ocular perfusion pressure and retrobulbar blood flow in patients with glaucoma with progressive damage. Am J Ophthalmol. 2000;130(5):597-605.
9. Gasser P, Flammer J. Blood-cell velocity in the nailfold capillaries of patients with normal-tension and high-tension glaucoma. Am J Ophthalmol. 1991;111(5):585-588.
10. Drance SM, Douglas GR, Wijsman K, Schulzer M, Britton RJ. Response of blood flow to warm and cold in normal and low-tension glaucoma patients. Am J Ophthalmol. 1988;105(1):35-39. (Pubitemid 18021341)
11. Su W-W, Cheng S-T, Hsu T-S, Ho W-J. Abnormal flow-mediated vasodilation in normal-tension glaucoma using a noninvasive determination for peripheral endothelial dysfunction. Invest Ophthalmol Vis Sci. 2006;47(8):3390-3394. (Pubitemid 351639702)
12. Oettli A, Gugleta K, Kochkorov A, Katamay R, Flammer J, Orgul S. Rigidity of retinal vessel in untreated eyes of normal tension primary open-angle glaucoma patients. J Glaucoma. 2011;20(5):303-306.
13. Collaborative Normal-Tension Glaucoma Study Group. Comparison of glaucomatous progression between untreated patients with normal-tension glaucoma and patients with therapeutically reduced intraocular pressures. Am J Ophthalmol. 1998;126(4):487-497.
14. Collaborative Normal-Tension Glaucoma Study Group. The effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucoma. Am J Ophthalmol. 1998;126(4):498-505.
15. Heijl A, Leske MC, Bengtsson B, Hyman L, Bengtsson B, Hussein M; Early Manifest Glaucoma Trial Group. Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial. Arch Ophthalmol. 2002;120(10):1268-1279. (Pubitemid 36105431)
16. Cartwright MJ, Anderson DR. Correlation of asymmetric damage with asymmetric intraocular pressure in normal-tension glaucoma (low-tension glaucoma). Arch Ophthalmol. 1988;106(7):898-900.
17. EGS. European Glaucoma Society: Terminology and Guidelines for Glaucoma. 3rd ed. Savona, Italy: Dogma; 2008.
18. Sommer A. Ocular hypertension and normal-tension glaucoma: time for banishment and burial. Arch Ophthalmol. 2011;129(6):785-787.
19. Shields MB. Normal-tension glaucoma: is it different from primary open-angle glaucoma? Curr Opin Ophthalmol. 2008;19(2):85-88. (Pubitemid 351322808)
20. Shields MB, Spaeth GL. The glaucomatous process and the evolving definition of glaucoma. J Glaucoma. 2012;21(3):141-143.
21. Caprioli J, Spaeth GL. Comparison of the optic nerve head in high- and low-tension glaucoma. Arch Ophthalmol. 1985;103(8):1145-1149. (Pubitemid 15024624)
22. Fazio P, Krupin T, Feitl ME, Werner EB, Carre DA. Optic disc topography in patients with low-tension and primary open angle glaucoma. Arch Ophthalmol. 1990;108(5):705-708. (Pubitemid 20168831)
23. Thonginnetra O, Greenstein VC, Chu D, Liebmann JM, Ritch R, Hood DC. Normal versus high tension glaucoma: a comparison of functional and structural defects. J Glaucoma. 2010;19(3):151-157.
24. Asrani S, Samuels B, Thakur M, Santiago C, Kuchibhatla M. Clinical profiles of primary open angle glaucoma versus normal tension glaucoma patients: a pilot study. Curr Eye Res. 2011;36(5):429-435.
25. Sowka J. New thoughts on normal tension glaucoma. Optometry. 2005;76(10):600-608. (Pubitemid 41608102)
26. Caprioli J, Spaeth GL. Comparison of visual field defects in the low-tension glaucomas with those in the high-tension glaucomas. Am J Ophthalmol. 1984;97(6):730-737. (Pubitemid 14082960)
27. Hitchings RA, Anderton SA. A comparative study of visual field defects seen in patients with low-tension glaucoma and chronic simple glaucoma. Br J Ophthalmol. 1983;67(12):818-821. (Pubitemid 14213515)
28. National Collaborating Centre for Acute Care. Glaucoma: Diagnosis and Management of Chronic Open Angle Glaucoma and Ocular Hypertension: NICE Clinical Guideline 85. London, England: National Institute for Health and Clinical Excellence; 2009.
29. Patel SR, Bellary S, Qin L, et al. Abnormal retinal vascular function and lipid levels in a sample of healthy UK South Asians. Br J Ophthalmol. 2011;95(11):1573-1576.
30. O'Brien E, Atkins N, Stergiou G, et al Working Group on Blood Pressure Monitoring of the European Society of Hypertension. European Society of Hypertension International Protocol revision 2010 for the validation of blood pressure measuring devices in adults. Blood Press Monit. 2010;15(1):23-38. doi:10.1097/MBP.1090b1013e3283360e3283398.
31. Donic V, Donicová V, Lesko R, Tomori Z. Blood pressure and heart rate monitoring as a method of detection of sleep apnea. Sb Lek. 2002;103(1):85-90.
32. Gherghel D, Hosking SL, Cunliffe IA, Heitmar R. Transient cardiac ischaemia and abnormal variations in systemic blood pressure in unselected primary open angle glaucoma patients. Ophthalmic Physiol Opt. 2010;30(2):175-181.
33. Heitmar R, Cubbidge RP, Lip GY, Gherghel D, Blann AD. Altered blood vessel responses in the eye and finger in coronary artery disease. Invest Ophthalmol Vis Sci. 2011;52(9):6199-6205.
34. O'Rourke MF, Pauca A, Jiang XJ. Pulse wave analysis. Br J Clin Pharmacol. 2001;51(6):507-522. (Pubitemid 32862740)
35. Wilkinson IB, Fuchs SA, Jansen IM, et al. Reproducibility of pulse wave velocity and augmentation index measured by pulse wave analysis. J Hypertens. 1998;16(12, pt 2):2079-2084. (Pubitemid 29002391)
36. Salonen R, Haapanen A, Salonen JT. Measurement of intima-media thickness of common carotid arteries with high-resolution B-mode ultrasonography: interand intra-observer variability. Ultrasound Med Biol. 1991;17(3):225-230.
37. Nagel E, Vilser W, Lanzl I. Age, blood pressure, and vessel diameter as factors influencing the arterial retinal flicker response. Invest Ophthalmol Vis Sci. 2004;45(5):1486-1492. (Pubitemid 38859329)
38. Garhofer G, Bek T, Boehm AG, et al Ocular Blood Flow Research Association. Use of the retinal vessel analyzer in ocular blood flow research. Acta Ophthalmol. 2010;88(7):717-722.
39. Mroczkowska S, Ekart A, Sung V, et al. Coexistence of macro- and microvascular abnormalities in newly diagnosed normal tension glaucoma patients. Acta Ophthalmol (Copenh). In press. doi:10.1111/j.1755-3768.2012.02494.x.
40. Tokunaga T, Kashiwagi K, Tsumura T, Taguchi K, Tsukahara S. Association between nocturnal blood pressure reduction and progression of visual field defect in patients with primary open-angle glaucoma or normal-tension glaucoma. Jpn J Ophthalmol. 2004;48(4):380-385. (Pubitemid 39013906)
41. Riccadonna M, Covi G, Pancera P, et al. Autonomic system activity and 24-hour blood pressure variations in subjects with normal- and high-tension glaucoma. J Glaucoma. 2003;12(2):156-163. (Pubitemid 36427704)
42. Kim YK, Oh WH, Park KH, Kim JM, Kim DM. Circadian blood pressure and intraocular pressure patterns in normal tension glaucoma patients with undisturbed sleep. Korean J Ophthalmol. 2010;24(1):23-28.
43. Leske MC, Heijl A, Hyman L, Bengtsson B, Dong L, Yang Z; EMGT Group. Predictors of long-term progression in the early manifest glaucoma trial. Ophthalmology. 2007;114(11):1965-1972. (Pubitemid 350016362)
44. Hayreh SS, Zimmerman MB, Podhajsky P, Alward WL. Nocturnal arterial hypotension and its role in optic nerve head and ocular ischemic disorders. Am J Ophthalmol. 1994;117(5):603-624. (Pubitemid 24150730)
45. Kaiser HJ, Flammer J, Graf T, Stümpfig D. Systemic blood pressure in glaucoma patients. Graefes Arch Clin Exp Ophthalmol. 1993;231(12):677-680. (Pubitemid 24026550)
46. Béchetoille A, Bresson-Dumont H. Diurnal and nocturnal blood pressure drops in patients with focal ischemic glaucoma. Graefes Arch Clin Exp Ophthalmol. 1994;232(11):675-679. (Pubitemid 24313572)
47. Hayreh SS, Podhajsky P, Zimmerman MB. Beta-blocker eyedrops and nocturnal arterial hypotension. Am J Ophthalmol. 1999;128(3):301-309. (Pubitemid 29413226)
48. Liu JHK, Zhang X, Kripke DF, Weinreb RN. Twenty-four-hour intraocular pressure pattern associated with early glaucomatous changes. Invest Ophthalmol Vis Sci. 2003;44(4):1586-1590. (Pubitemid 36378585)
49. Graham SL, Drance SM, Wijsman K, Douglas GR, Mikelberg FS. Ambulatory blood pressure monitoring in glaucoma: the nocturnal dip. Ophthalmology. 1995;102(1):61-69.
50. Wostyn P, Audenaert K, De Deyn PP. The Valsalva maneuver and Alzheimer's disease: is there a link? Curr Alzheimer Res. 2009;6(1):59-68.
51. Kaiser HJ, Flammer J. Systemic hypotension: a risk factor for glaucomatous damage? Ophthalmologica. 1991;203(3):105-108.
52. Collignon N, Dewe W, Guillaume S, Collignon-Brach J. Ambulatory blood pressure monitoring in glaucoma patients: the nocturnal systolic dip and its relationship with disease progression. Int Ophthalmol. 1998;22(1):19-25. (Pubitemid 29083231)
53. Bresson-Dumont H, Bechetoille A. Role of arterial blood pressure in the development of glaucomatous lesions. J Fr Ophtalmol. 1996;19(6-7):435-442. (Pubitemid 26233063)
54. Meyer JH, Brandi-Dohrn J, Funk J. Twenty four hour blood pressure monitoring in normal tension glaucoma. Br J Ophthalmol. 1996;80(10):864-867. (Pubitemid 26366552)
55. Stroman GA, Stewart WC, Golnik KC, Curé JK, Olinger RE. Magnetic resonance imaging in patients with low-tension glaucoma. Arch Ophthalmol. 1995;113(2):168-172.
56. Su D-F, Miao C-Y. Blood pressure variability and organ damage. Clin Exp Pharmacol Physiol. 2001;28(9):709-715. (Pubitemid 34204375)
57. Joe SG, Choi J, Sung KR, Park SB, Kook MS. Twenty-four hour blood pressure pattern in patients with normal tension glaucoma in the habitual position. Korean J Ophthalmol. 2009;23(1):32-39.
58. Plange N, Kaup M, Daneljan L, Predel HG, Remky A, Arend O. 24-h blood pressure monitoring in normal tension glaucoma: night-time blood pressure variability. J Hum Hypertens. 2006;20(2):137-142. (Pubitemid 43148615)
59. Sugiyama T, Utsunomiya K, Ota H, Ogura Y, Narabayashi I, Ikeda T. Comparative study of cerebral blood flow in patients with normal-tension glaucoma and control subjects. Am J Ophthalmol. 2006;141(2):394-396. (Pubitemid 43188054)
60. Choi J, Kim KH, Jeong J, Cho H-S, Lee CH, Kook MS. Circadian fluctuation of mean ocular perfusion pressure is a consistent risk factor for normal-tension glaucoma. Invest Ophthalmol Vis Sci. 2007;48(1):104-111. (Pubitemid 47251393)
61. Sung KR, Lee S, Park SB, et al. Twenty-four hour ocular perfusion pressure fluctuation and risk of normal-tension glaucoma progression. Invest Ophthalmol Vis Sci. 2009;50(11):5266-5274.
62. Choi J, Jeong J, Cho HS, Kook MS. Effect of nocturnal blood pressure reduction on circadian fluctuation of mean ocular perfusion pressure: a risk factor for normal tension glaucoma. Invest Ophthalmol Vis Sci. 2006;47(3):831-836. (Pubitemid 46768313)
63. Leske MC, Wu S-Y, Hennis A, Honkanen R, Nemesure B; BESs Study Group. Risk factors for incident open-angle glaucoma: the Barbados Eye Studies. Ophthalmology. 2008;115(1):85-93. (Pubitemid 350309410)
64. Asrani S, Zeimer R, Wilensky J, Gieser D, Vitale S, Lindenmuth K. Large diurnal fluctuations in intraocular pressure are an independent risk factor in patients with glaucoma. J Glaucoma. 2000;9(2):134-142. (Pubitemid 32441322)
65. Cohn JN. Arterial stiffness, vascular disease, and risk of cardiovascular events. Circulation. 2006;113(5):601-603.
66. Simon A, Gariepy J, Chironi G, Megnien J-L, Levenson J. Intima-media thickness: a new tool for diagnosis and treatment of cardiovascular risk. J Hypertens. 2002;20(2):159-169. (Pubitemid 34913777)
67. Hulsman CA, Vingerling JR, Hofman A, Witteman JC, de Jong PT. Blood pressure, arterial stiffness, and open-angle glaucoma: the Rotterdam study. Arch Ophthalmol. 2007;125(6):805-812. (Pubitemid 46919742)
68. Visontai Z, Mersich B, Holló G. Carotid artery elasticity and baroreflex sensitivity in patients with glaucoma. J Glaucoma. 2005;14(1):30-35. (Pubitemid 40165489)
69. Siasos G, Tousoulis D, Siasou G, et al. The association between glaucoma, vascular function and inflammatory process. Int J Cardiol. 2011;146(1):113-115.
70. Güngör IU, Güngör L, Ozarslan Y, et al. Is symptomatic atherosclerotic cerebrovascular disease a risk factor for normal-tension glaucoma? Med Princ Pract. 2011;20(3):220-224.
71. Ohguro I, Ishikawa F, Ohguro H, Shimokawa R, Nakazawa M. Arterial sclerosis grade in normal-tension glaucoma patients. J Eye. 2004;21(3):397-400.
72. Chiba T, Chiba N, Kashiwagi K. Systemic arterial stiffness in glaucoma patients. J Glaucoma. 2008;17(1):15-18. (Pubitemid 351321470)
73. de Voogd S, Wolfs RCW, Jansonius NM, Witteman JCM, Hofman A, de Jong PTVM. Atherosclerosis, C-reactive protein, and risk for open-angle glaucoma: the Rotterdam study. Invest Ophthalmol Vis Sci. 2006;47(9):3772-3776. (Pubitemid 46044289)
74. Stewart WC, Sine C, Sutherland S, Stewart JA. Total cholesterol and high-density lipoprotein levels as risk factors for increased intraocular pressure. Am J Ophthalmol. 1996;122(4):575-577. (Pubitemid 26329694)
75. Ramdas WD, Wolfs RCW, Hofman A, de Jong PTVM, Vingerling JR, Jansonius NM. Lifestyle and risk of developing open-angle glaucoma: the Rotterdam study. Arch Ophthalmol. 2011;129(6):767-772.
76. Coutinho T, Rooke TW, Kullo IJ. Arterial dysfunction and functional performance in patients with peripheral artery disease: a review. Vasc Med. 2011;16(3):203-211.
77. Gugleta K, Zawinka C, Rickenbacher I, et al. Analysis of retinal vasodilation after flicker light stimulation in relation to vasospastic propensity. Invest Ophthalmol Vis Sci. 2006;47(9):4034-4041. (Pubitemid 46044321)
78. Flammer J, Pache M, Resink T. Vasospasm, its role in the pathogenesis of diseases with particular reference to the eye. Prog Retin Eye Res. 2001;20(3):319-349. (Pubitemid 32245685)
79. Sugiyama T, Moriya S, Oku H, Azuma I. Association of endothelin-1 with normal tension glaucoma: clinical and fundamental studies. Surv Ophthalmol. 1995;39(suppl 1):S49-S56.
80. Heitmar R, Blann AD, Cubbidge RP, Lip GY, Gherghel D. Continuous retinal vessel diameter measurements: the future in retinal vessel assessment? Invest Ophthalmol Vis Sci. 2010;51(11):5833-5839.
81. Kochkorov A, Gugleta K, Zawinka C, Katamay R, Flammer J, Orgul S. Short-term retinal vessel diameter variability in relation to the history of cold extremities. Invest Ophthalmol Vis Sci. 2006;47(9):4026-4033. (Pubitemid 46044320)
82. Kotliar KE, Nagel E, Vilser W, Lanzl IM. Functional in vivo assessment of retinal artery microirregularities in glaucoma. Acta Ophthalmol. 2008;86(4):424-433.
83. Klijn CJM, Kappelle LJ, van Schooneveld MJ, et al. Venous stasis retinopathy in symptomatic carotid artery occlusion. Stroke. 2002;33(3):695-701. (Pubitemid 34203992)
84. de Jong FJ, Vernooij MW, Ikram MK, et al. Arteriolar oxygen saturation, cerebral blood flow, and retinal vessel diameters: the Rotterdam Study. Ophthalmology. 2008;115(5):887-892.