Rapid and highly specific screening for NPM1 mutations in acute myeloid leukemia

Annals of Hematology

Volumn 92, Issue 2, 2013, Pages 173-177

  Oppliger Leibundgut, Elisabeth ^a   Porret, Naomi A ^a   Bienz Muggli, Marianne ^a   Baumgartner, Heidi ^a   Dahlhaus, Meike ^a   Baerlocher, Gabriela M ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Acute myeloid leukemia; Mutation detection; NPM1; Sensitivity; Specificity

Indexed keywords

NUCLEOPHOSMIN;

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ADULT; AGAR GEL ELECTROPHORESIS; AGED; ARTICLE; CANCER RISK; CANCER SCREENING; CHROMOSOME ABERRATION; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; EXON; FAST POLYMERASE CHAIN REACTION; FEMALE; FRAMESHIFT MUTATION; GENE DELETION; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC RISK; HUMAN; INTERMETHOD COMPARISON; LIMIT OF DETECTION; MAJOR CLINICAL STUDY; MALE; MUTATIONAL ANALYSIS; NUCLEOPHOSMIN GENE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PREDICTIVE VALUE; PRIORITY JOURNAL; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; STOP CODON;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; DNA MUTATIONAL ANALYSIS; DNA, COMPLEMENTARY; DNA, NEOPLASM; ELECTROPHORESIS, AGAR GEL; EXONS; FEMALE; FRAMESHIFT MUTATION; GENETIC TESTING; HUMANS; LEUKEMIA, MYELOID, ACUTE; LEUKEMIA, MYELOMONOCYTIC, ACUTE; MALE; MIDDLE AGED; MUTAGENESIS, INSERTIONAL; NEOPLASM PROTEINS; NUCLEAR PROTEINS; ONCOGENE PROTEINS, FUSION; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; TIME FACTORS; YOUNG ADULT;

EID: 84872348708     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-012-1617-9     Document Type: Article

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