The effect of acute exercise on collagen turnover in human tendons: Influence of prior immobilization period

European Journal of Applied Physiology

Volumn 113, Issue 2, 2013, Pages 449-455

  Moerch, L ^a   Pingel, J ^a   Boesen, M ^a   Kjaer, M ^a   Langberg, Henning ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Blood flow velocity; Immobilization; Microdialysis; Power Doppler; Procollagen type I N terminal peptide

Indexed keywords

COLLAGEN;

ACHILLES TENDON; ADULT; ARTICLE; ENDURANCE; HUMAN; IMMOBILIZATION; MALE; METABOLIC CLEARANCE RATE; METABOLISM; METHODOLOGY; PHYSIOLOGY; WEIGHT BEARING;

ACHILLES TENDON; COLLAGEN; HUMANS; IMMOBILIZATION; MALE; METABOLIC CLEARANCE RATE; PHYSICAL ENDURANCE; WEIGHT-BEARING; YOUNG ADULT;

EID: 84872321970     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00421-012-2450-5     Document Type: Article

References (39)

1. Birch HL, McLaughlin L, Smith RK, Goodship AE (1999) Treadmill exercise-induced tendon hypertrophy: assessment of tendons with different mechanical functions. Equine Vet J Suppl 30:222-226
2. Boesen MI, Koenig MJ, Torp-Pedersen S, Bliddal H, Langberg H (2006a) Tendinopathy and Doppler activity: the vascular response of the achilles tendon to exercise. Scand J Med Sci Sports 16:463-469
3. Boesen MI, Torp-Pedersen S, Koenig MJ, Christensen R, Langberg H, Holmich P, Nielsen MB, Bliddal H (2006b) Ultrasound guided electrocoagulation in patients with chronic non-insertional Achilles tendinopathy: a pilot study. Br J Sports Med 40:761-766
4. Christensen B, Dyrberg E, Aagaard P, Enehjelm S, Krogsgaard M, Kjaer M, Langberg H (2008a) Effects of long-term immobilization and recovery on human triceps surae and collagen turnover in the Achilles tendon in patients with healing ankle fracture. J Appl Physiol 105:420-426
5. Christensen B, Dyrberg E, Aagaard P, Kjaer M, Langberg H (2008b) Short-term immobilization and recovery affect skeletal muscle but not collagen tissue turnover in humans. J Appl Physiol 105:1845-1851
6. Cook JL, Kiss ZS, Ptasznik R, Malliaras P (2005) Is vascularity more evident after exercise? Implications for tendon imaging. AJR 185:1138-1140
7. Couppe C, Kongsgaard M, Aagaard P, Hansen P, Bojsen-Moller J, Kjaer M, Magnusson SP (2008) Habitual loading results in tendon hypertrophy and increased stiffness of the human patellar tendon. J Appl Physiol 105:805-810
8. de Boer MD, Selby A, Atherton P, Smith K, Seynnes OR, Maganaris CN, Maffulli N, Movin T, Narici MV, Rennie MJ (2007) The temporal responses of protein synthesis, gene expression and cell signalling in human quadriceps muscle and patellar tendon to disuse. J Physiol 585:241-251
9. Doessing S, Heinemeier KM, Holm L, Mackey AL, Schjerling P, Rennie M, Smith K, Reitelseder S, Kappelgaard AM, Rasmussen MH, Flyvbjerg A, Kjaer M (2010) Growth hormone stimulates the collagen synthesis in human tendon and skeletal muscle without affecting myofibrillar protein synthesis. J Physiol 588:341-351
10. Eliasson P, Andersson T, Aspenberg P (2009) Rat Achilles tendon healing: mechanical loading and gene expression. J Appl Physiol 107:399-407
11. Eliasson P, Fahlgren A, Pasternak B, Aspenberg P (2007) Unloaded rat Achilles tendons continue to grow, but lose viscoelasticity. J Appl Physiol 103:459-463
12. Garnero P, Ferreras M, Karsdal MA, Nicamhlaoibh R, Risteli J, Borel O, Qvist P, Delmas PD, Foged NT, Delaisse JM (2003) The type I collagen fragments ICTP and CTX reveal distinct enzymatic pathways of bone collagen degradation. J Bone Miner Res 18:859-867
13. Hansen P, Aagaard P, Kjaer M, Larsson B, Magnusson SP (2003) Effect of habitual running on human Achilles tendon load-deformation properties and cross-sectional area. J Appl Physiol 95:2375-2380
14. Heinemeier K, Langberg H, Olesen JL, Kjaer M (2003) Role of TGF-beta1 in relation to exercise-induced type I collagen synthesis in human tendinous tissue. J Appl Physiol 95:2390-2397
15. Heinemeier KMOJ, Haddad F, Schjerling P, Baldwin KM, Kjaer M (2009) Effect of unloading followed by reloading on expression of collagen and related growth factors in rat tendon and muscle. J Appl Physiol 106:178-186
16. Kjaer M (2004) Role of extracellular matrix in adaptation of tendon and skeletal muscle to mechanical loading. Physiol Rev 84:649-698
17. Kjaer M, Magnusson P, Krogsgaard M, Boysen Moller J, Olesen J, Heinemeier K, Hansen M, Haraldsson B, Koskinen S, Esmarck B, Langberg H (2006) Extracellular matrix adaptation of tendon and skeletal muscle to exercise. J Anat 208:445-450
18. Koenig MJ, Torp-Pedersen S, Boesen MI, Holm CC, Bliddal H (2010) Doppler ultrasonography of the anterior knee tendons in elite badminton players: colour fraction before and after match. Br J Sports Med 44:134-139
19. Kongsgaard M, Aagaard P, Kjaer M, Magnusson SP (2005) Structural Achilles tendon properties in athletes subjected to different exercise modes and in Achilles tendon rupture patients. J Appl Physiol 99:1965-1971
20. Langberg H, Ellingsgaard H, Madsen T, Jansson J, Magnusson SP, Aagaard P, Kjaer M (2007) Eccentric rehabilitation exercise increases peritendinous type i collagen synthesis in humans with Achilles tendinosis. Scand J Med Sci Sports 17:61-66
21. Langberg H, Rosendal L, Kjaer M (2001) Training-induced changes in peritendinous type I collagen turnover determined by microdialysis in humans. J Physiol 534:297-302
22. Langberg H, Skovgaard D, Karamouzis M, Bulow J, Kjaer M (1999a) Metabolism and inflammatory mediators in the peritendinous space measured by microdialysis during intermittent isometric exercise in humans. J Physiol 515(Pt 3):919-927
23. Langberg H, Skovgaard D, Petersen LJ, Bulow J, Kjaer M (1999b) Type I collagen synthesis and degradation in peritendinous tissue after exercise determined by microdialysis in humans. J Physiol 521(Pt 1):299-306
24. Loitz BJ, Zernicke RF, Vailas AC, Kody MH, Meals RA (1989) Effects of short-term immobilization versus continuous passive motion on the biomechanical and biochemical properties of the rabbit tendon. Clin Orthop Relat Res 265-271
25. Magnusson SP, Langberg H, Kjaer M (2010) The pathogenesis of tendinopathy: balancing the response to loading. Nat Rev Rheumatol 6:262-268
26. Miller BF, Olesen JL, Hansen M, Dossing S, Crameri RM, Welling RJ, Langberg H, Flyvbjerg A, Kjaer M, Babraj JA, Smith K, Rennie MJ (2005) Coordinated collagen and muscle protein synthesis in human patella tendon and quadriceps muscle after exercise. J Physiol 567:1021-1033
27. Miyahara M, Njieha FK, Prockop DJ (1982) Formation of collagen fibrils in vitro by cleavage of procollagen with procollagen proteinases. J Biol Chem 257:8442-8448
28. Olesen JL, Heinemeier KM, Gemmer C, Kjaer M, Flyvbjerg A, Langberg H (2007) Exercise-dependent IGF-I, IGFBPS, and type I collagen changes in human peritendinous connective tissue determined by microdialysis. J Appl Physiol 102:214-220
29. Pingel J, Moerch L, Kjaer M, Langberg H (2009) The influence of training status on the drop in muscle strength after acute exercise. Eur J Appl Physiol 106:605-611
30. Reeves ND, Maganaris CN, Ferretti G, Narici MV (2005) Influence of 90-day simulated microgravity on human tendon mechanical properties and the effect of resistive countermeasures. J Appl Physiol 98:2278-2286
31. Reeves ND, Maganaris CN, Narici MV (2003a) Effect of strength training on human patella tendon mechanical properties of older individuals. J Physiol 548:971-981
32. Reeves ND, Narici MV, Maganaris CN (2003b) Strength training alters the viscoelastic properties of tendons in elderly humans. Muscle Nerve 28:74-81
33. Rosager S, Aagaard P, Dyhre-Poulsen P, Neergaard K, Kjaer M, Magnusson SP (2002) Load-displacement properties of the human triceps surae aponeurosis and tendon in runners and non-runners. Scand J Med Sci Sports 12:90-98
34. Scheller D, Kolb J (1991) The internal reference technique in microdialysis: a practical approach to monitoring dialysis efficiency and to calculating tissue concentration from dialysate samples. J Neurosci Methods 40:31-38
35. Shin D, Finni T, Ahn S, Hodgson JA, Lee HD, Edgerton VR, Sinha S (2008) Effect of chronic unloading and rehabilitation on human Achilles tendon properties: a velocity-encoded phase-contrast MRI study. J Appl Physiol 105:1179-1186
36. Sun YL, Thoreson AR, Cha SS, Zhao C, An KN, Amadio PC (2010) Temporal response of canine flexor tendon to limb suspension. J Appl Physiol 109:1762-1768
37. Vailas AC, Deluna DM, Lewis LL, Curwin SL, Roy RR, Alford EK (1988) Adaptation of bone and tendon to prolonged hindlimb suspension in rats. J Appl Physiol 65:373-376
38. Woo SL, Gomez MA, Amiel D, Ritter MA, Gelberman RH, Akeson WH (1981) The effects of exercise on the biomechanical and biochemical properties of swine digital flexor tendons. J Biomech Eng 103:51-56
39. Woo SL, Ritter MA, Amiel D, Sanders TM, Gomez MA, Kuei SC, Garfin SR, Akeson WH (1980) The biomechanical and biochemical properties of swine tendons - long term effects of exercise on the digital extensors. Connect Tissue Res 7:177-183