The immune response induced by DNA vaccine expressing nfa1 gene against Naegleria fowleri

Parasitology Research

Volumn 111, Issue 6, 2012, Pages 2377-2384

  Kim, Jong Hyun ^a   Lee, Sang Hee ^a   Sohn, Hae Jin ^a   Lee, Jinyoung ^a   Chwae, Yong Joon ^a   Park, Sun ^a   Kim, Kyongmin ^a   Shin, Ho Joon ^a  

^a Ajou University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; LENTIVIRUS VECTOR; RETROVIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; CELLULAR IMMUNITY; CHO CELL; CONTROLLED STUDY; DNA IMMUNIZATION; DRUG EFFICACY; EPITHELIUM CELL; FEMALE; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; MOUSE; NAEGLERIA FOWLERI; NFA1 GENE; NONHUMAN; NOSE MUCOSA; NUCLEOTIDE SEQUENCE; PARASITE IMMUNITY; PRIMARY AMEBIC MENINGOENCEPHALITIS; PRIORITY JOURNAL; TH1 CELL; TH2 CELL; VIRUS PARTICLE;

AMEBIASIS; ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; CELL LINE; CENTRAL NERVOUS SYSTEM PROTOZOAL INFECTIONS; CRICETINAE; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GENETIC VECTORS; HUMANS; IMMUNOGLOBULIN G; LENTIVIRUS; MICE; MICE, INBRED BALB C; NAEGLERIA FOWLERI; PROTOZOAN PROTEINS; PROTOZOAN VACCINES; TH1 CELLS; TH2 CELLS; VACCINES, DNA; VACCINES, SYNTHETIC;

ANIMALIA; CRICETULUS GRISEUS; MUS; NAEGLERIA FOWLERI;

EID: 84872310187     PISSN: 09320113     EISSN: 14321955     Source Type: Journal    
DOI: 10.1007/s00436-012-3093-5     Document Type: Article

References (37)

1. Ahmed SB, Touihri L, Chtourou Y, Dellagi K, Bahloul C (2009) DNA based vaccination with a cocktail of plasmids encoding immunodominant Leishmania (Leishmania) major antigens confers full protection in BALB/c mice. Vaccine 27:99-106
2. Anderson K, Jamieson A (1972) Primary amoebic meningoencephalitis. Lancet 2:379
3. Apley J, Clarke SK, Roome AP, Sandry SA, Saygi G, Silk B, Warhurst DC (1970) Primary amoebic meningoencephalitis in Britain. Br Med J 7:596-599
4. Carter RF (1968) Primary amoebic meningoencephalitis: clinical, pathological and epidemiological features of six fatal cases. J Pathol Bacteriol 96:1-25
5. Carter RF (1972) Primary amoebic meningo-encephalitis. An appraisal of present knowledge. Trans R Soc Trop Med Hyg 66:193-213
6. Cho MS, Jung SY, Park S, Kim KH, Kim HI, Sohn S, Kim HJ, Im KI, Shin HJ (2003) Immunological characterizations of a cloned 13.1-kilodalton protein from pathogenic Naegleria fowleri. Clin Diagn Lab Immunol 10:954-959
7. Culbertson CG (1970) Pathogenic Naegleria and Hartmannella (Acanthamoeba). Ann N Y Acad Sci 74:1018-1022
8. Gurunathan S, Wu C, Freidag BL, Seder RA (2000) DNA vaccines: a key for inducing long-term cellular immunity. Curr Opin Immunol 12:442-447
9. Haan L, Verweij WR, Holtrop M, Brands R, Van Scharrenburg GJ, Palache AM, Agsteribbe E,Wilschut J (2001) Nasal or intramuscular immunization of mice with influenza subunit antigen and the B subunit of Escherichia coli heat-labile toxin induces IgA- or IgGmediated protective mucosal immunity. Vaccine 19:2898-2907
10. Holmgren J, Czerkinsky C (2005) Mucosal immunity and vaccines. Nat Med 11(suppl 4):S45-S53
11. Jeong SY, Kang SY, Lee SC, Song KJ, Im KI, Shin HJ (2004) Decreasing effect of an anti-Nfa1 polyclonal antibody on the in vitro cytotoxicity of pathogenic Naegleria fowleri. Kor J Parasitol 42:35-40
12. Kang SY, Song KJ, Jeong SR, Kim JH, Park S, Kim K, Kwon MH, Shin HJ (2005) Role of the Nfa1 protein in pathogenic Naegleria fowleri co-cultured with CHO target cells. Clin Diagn Lab Immunol 12:873-876
13. Khosroshahi KH, Ghaffarifar F, Sharifi Z, D'Souza S, Dalimi A, Hassan ZM, Khoshzaban F (2012) Comparing the effect of IL-12 genetic adjuvant and alum non-genetic adjuvant on the efficiency of the cocktail DNA vaccine containing plasmids encoding SAG-1 and ROP-2 of Toxoplasma gondii. Parasitol Res 111:403-411
14. Lee YJ, Kim JH, Jeong SR, Song KJ, Kim K, Park S, Park MS, Shin HJ (2007) Production of Nfa1-specific monoclonal antibodies that influences the in vitro cytotoxicity of Naegleria fowleri trophozoites on microglial cells. Parasitol Res 101:1191-1196
15. Lee YJ, Kim JH, Sohn HJ, Lee J, Jung SY, Chwae YJ, Kim K, Park S, Shin HJ (2011) Effects of immunization with the rNfa1 protein on experimental Naegleria fowleri-PAM mice. Parasite Immunol 33:382-389
16. Liljeqvist S, Ståhl S (1999) Production of recombinant subunit vaccines: protein immunogens, live delivery systems and nucleic acid vaccines. J Biotechnol 73:1-33
17. Limon-Flores AY, Cervera-Cetina R, Tzec-Arjona JL, Ek-Macias L, Sánchez-Burgos G, Ramirez-Sierra MJ, Cruz-Chan JV, VanWynsberghe NR, Dumonteil E (2011) Effect of a combination DNA vaccine for the prevention and therapy of Trypanosoma cruzi infection in mice: role of CD4+ and CD8+ T cells. Vaccine 28:7414-7419
18. Liu MA, Wahren B, Karlsson Hedestam GB (2006) DNA vaccines: recent developments and future possibilities. Hum Gene Ther 17:1051-1061
19. Loschiavo F, Ventura-Spagnolo T, Sessa E, Bramanti P (1993) Acute primary meningoencephalitis from entamoeba Naegleria fowleri. Report of a clinical case with a favourable outcome. Acta Neurol 15:333-340
20. Ma P, Visvesvara GS, Martinez AJ, Theodore FH, Gaggett PM, Sawyer TK (1990) Naegleria and Acanthamoeba infections: review. Rev Infect Dis 12:490-513
21. Martínez MB, Rodríguez MA, García-Rivera G, Sánchez T, Hernández- Pando R, Aguilar D, Orozco E (2009) A pcDNA-Ehcpadh vaccine against Entamoeba histolytica elicits a protective Th1-like response in hamster liver. Vaccine 27:4176-4186
22. Mascola JR, Nabel GJ (2001) Vaccines for the prevention of HIV-1 disease. Curr Opin Immunol 13:489-495
23. Miller AD, Rosman GJ (1989) Improved retroviral vectors for gene transfer and expression. Biotechniques 7:980-990
24. Mustafa AS (2001) Biotechnology in the development of new vaccines and diagnostic reagents against tuberculosis. Curr Pharm Biotechnol 2:157-173
25. Negri DR, Michelini Z, Bona R, Blasi M, Filati P, Leone P, Rossi A, Franco M, Cara A (2011) Integrase-defective lentiviral-vectorbased vaccine: a new vector for induction of T cell immunity. Expert Opin Biol Ther 11:739-750
26. Poungvarin N, Jariya P (1991) The fifth nonlethal case of primary amoebic meningoencephalitis. J Med Assoc Thai 74:112-115
27. Proffitt RT, Satorius A, Chiang SM, Sullivan L, Adler-Moore JP (1991) Pharmacology and toxicology of a liposomal formulation of amphotericin B (AmBisome) in rodents. J Antimicrob Chemother 28(suppl B):49-61
28. Rappuoli R, Pizza M, Douce G, Dougan G (1999) Structure and mucosal adjuvanticity of cholera and Escherichia coli heat-labile enterotoxins. Immunol Today 20:493-500
29. Rivera-Aguilar V, Hernández-Martínez D, Rojas-Hernández S, Oliver- Aguillón G, Tsutsumi V, Herrera-González N, Campos-Rodríguez R (2000) Immunoblot analysis of IgA antibodies to Naegleria fowleri in human saliva and serum. Parasitol Res 86:775-780
30. Robinson HL (1997) Nucleic acid vaccines: an overview. Vaccine 15:785-787
31. Seidel JS, Harmatz P, Visvesvara GS, Cohen A, Edwards J, Turner J (1982) Successful treatment of primary amebic meningoencephalitis. N Engl J Med 11:346-348
32. Shin HJ, Cho MS, Jung SY, Kim HI, Park S, Kim HJ, Im KI (2001) Molecular cloning and characterization of a gene encoding a 13.1 kDa antigenic protein of Naegleria fowleri. J Eukaryot Microbiol 48:713-717
33. Snow MJ, Stanley SL (2006) Recent progress in vaccines for amebiasis. Arch Med Res 37:280-287
34. Stevens AR, Shulman ST, Lansen TA, Cichon MJ, Willaert E (1981) Primary amoebic meningoencephalitis: a report of two cases and antibiotic and immunologic studies. J Infect Dis 143:193-199
35. Tian Z, Wang SP, Zeng SH, Liu XQ, Gao DM, Feng QM, Zhang SJ, Zhou YF, Wang XY, Xia YD (2012) Characterization and vaccination of two novel Schistosoma japonicum genes screened from a cercaria cDNA library. Parasitol Res 110:403-409
36. Wang A, Kay R, Poon WS, Ng HK (1993) Successful treatment of amoebic meningoencephalitis in a Chinese living in Hong Kong. Clin Neurol Neurosurg 95:249-252
37. Wolff JA, Malone RW, Williams P, Chong W, Acsadi G, Jani A, Felgner PL (1990) Direct gene transfer into mouse muscle in vivo. Science 247:1465-1468