Tacrolimus pharmacokinetics in the early post-liver transplantation period and clinical applicability via Bayesian prediction

European Journal of Clinical Pharmacology

Volumn 69, Issue 1, 2013, Pages 65-74

  Oteo, Itziar ^a   Lukas, John C ^b   Leal, Nerea ^b   Suarez, Elena ^a   Valdivieso, Andres ^a,c   Gastaca, Mikel ^a,c   Ortiz De Urbina, Jorge ^a,c   Calvo, Rosario ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b Dynakin SL   (Spain)

^c HOSPITAL DE CRUCES   (Spain)

Author keywords

Bayesian; Clinical use; Liver transplantation; Model; Population pharmacokinetics; Tacrolimus

Indexed keywords

ALBUMIN; ASPARTATE AMINOTRANSFERASE; AZATHIOPRINE; CORTICOSTEROID; TACROLIMUS;

ARTICLE; BAYES THEOREM; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; HEMATOCRIT; HUMAN; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MATHEMATICAL ANALYSIS; POSTOPERATIVE PERIOD; PREDICTION; PRIORITY JOURNAL; VALIDITY;

BAYES THEOREM; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LIVER TRANSPLANTATION; MODELS, BIOLOGICAL; TACROLIMUS;

EID: 84872293353     PISSN: 00316970     EISSN: 14321041     Source Type: Journal    
DOI: 10.1007/s00228-012-1300-z     Document Type: Article

References (24)

1. Taylor AL, Watson CJ, Bradley JA (2005) Immunosuppressive agents in solid organ transplantation: mechanisms of action and therapeutic efficacy. Crit Rev Oncol Hematol 56(1):23-46
2. Bussittil RW, Holt CD (1998) Tacrolimus is superior to cyclosporine in liver transplantation. Transplant Proc 30(5):2174-2178
3. Oteo I, Lukas JC, Leal N, Suarez E, Valdivieso A, Ortiz de Urbina J, Gastaca M, Calvo R (2011) Pathophysiological idiosyncrasies and pharmacokinetic realities may interfere with Tacrolimus dose titration in liver transplantation. Eur J Clin Pharmacol 67(7):671-679
4. Kapturczak MH, Meier-Kriesche HU, Kaplan B (2004) Pharmacology of calcineurin antagonists. Transplant Proc 36 [Suppl 2]:25S-32S
5. Mancinelli LM, Frassetto L, Floren LC, Dressler D, Carrier S, Bekersky I, Benet LZ, Christians U (2001) The pharmacokinetics and metabolic disposition of tacrolimus: a comparison across ethnic groups. Clin Pharmacol Ther 69(1):24-31
6. Masuda S, Inui K (2006) An up-date review on individualized dosage adjustment of calcineurin inhibitors in organ transplant patients. Pharmacol Ther 112(1):184-198
7. Wallemacq P, Armstrong VW, Brunet M, Haufroid V, Holt DW, Johnston A, Kuypers D, Le Meur Y, Marquet P, Oellerich M, Thervet E, Toenshoff B, Undre N, Weber LT, Westley IS, Mourad M (2009) Opportunities to optimize tacrolimus therapy in solid organ transplantation: report of the European consensus conference. Ther Drug Monit 31(2):139-152
8. Staatz CE, Willis C, Taylor PJ, Lynch SV, Tett SE (2003) Toward better outcomes with tacrolimus therapy: population pharmacokinetics and individualized dosage prediction in adult liver transplantation. Liver Transpl 9(2):130-137
9. Antignac M, Hulot JS, Boleslawski E, Hannoun L, Touitou Y, Farinotti R, Lechat P, Urien S (2005) Population pharmacokinetics of tacrolimus in full liver transplant patients: modelling of the post-operative clearance. Eur J Clin Pharmacol 61(5-6):409-416
10. Lee JY, Hahn HJ, Son IJ, Suh KS, Yi NJ, Oh JM, Shin WG (2006) Factors affecting the apparent clearance of tacrolimus in Korean adult liver transplant recipients. Pharmacotherapy 26(8):1069-1077
11. Fukudo M, Yano I, Shinsako K, Katsura T, Takada Y, Uemoto S, Inui K (2009) Prospective evaluation of the bayesian method for individualizing tacrolimus dose early after living-donor liver transplantation. J Clin Pharmacol 49(7):789-797
12. Staatz CE, Tett SE (2004) Clinical pharmacokinetics and pharmacodynamics of tacrolimus in solid organ transplantation. Clin Pharmacokinet 43(10):623-653
13. Fukudo M, Yano I, Fukatsu S, Saito H, Uemoto S, Kiuchi T, Tanaka K, Inui K (2003) Forecasting of blood tacrolimus concentrations based on the Bayesian method in adult patients receiving living-donor liver transplantation. Clin Pharmacokinet 42(13):1161-1178
14. Karafoulidou A, Suarez E, Anastasopoulou I, Katsarou O, Kouramba A, Kotsi P, Zografidis A, Lukas JC (2009) Population pharmacokinetics of recombinant factor VIII:C (ReFacto) in adult HIV-negative and HIV-positive haemophilia patients. Eur J Clin Pharmacol 65(11):1121-1130
15. Sheiner LB, Beal SL (1981) Some suggestions for measuring predictive performance. J Pharmacokinet Biopharm 9(4):503-512
16. Proost JH (1995) Adaptive control of drug dosage regimens using maximum a posteriori probability Bayesian fitting. Int J Clin Pharmacol Ther 33(10):531-536
17. Zahir H, McLachlan AJ, Nelson A, McCaughan G, Gleeson M, Akhlaghi F (2005) Population pharmacokinetic estimation of tacrolimus apparent clearance in adult liver transplant recipients. Ther Drug Monit 27(4):422-430
18. Akbas SH, Ozdem S, Caglar S, Tuncer M, Gurkan A, Yucetin L, Senol Y, Demirbas A, Gultekin M, Ersoy FF, Akaydin M (2005) Effects of some hematological parameters on whole blood tacrolimus concentration measured by two immunoassay-based analytical methods. Clin Biochem 38(6):552-557
19. Hospital Regional Universitario Carlos Haya (2001) "Protocolo de Trasplante Hepático" v.2000-2001. Hospital Regional Universitario Carlos Haya, Malaga
20. Nagase K, Iwasaki K, Nozaki K, Noda K (1994) Distribution and protein binding of FK506, a potent immunosuppressive macrolide lactone, in human blood and its uptake by erythrocytes. J Pharm Pharmacol 46:113-117
21. Zahir H, McCaughan G, Gleeson M, Nand RA, McLachlan AJ (2003) Factors affecting variability in distribution of tacrolimus in liver transplant recipients. Br J Pharmacol 57(3):298-309
22. Sam WJ, Tham LS, Holmes MJ, Aw M, Quak SH, Lee KH, Seng GL (2006) Population pharmacokinetics of Tacrolimus in whole blood and plasma in Asian liver transplant patients. Clin Pharmacokinet 45(1):59-75
23. Marin-Gomez LM, Gomez-Bravo MA, Alamo-Martinez JA, Barrera-Pulido L, Bernal Bellido C, Suárez Artacho G, Pascasio JM (2009) Evaluation of clinical safety of conversion to Advagraf therapy in liver transplant recipients: observational study. Transplant Proc 41(6):2184-2186
24. Fischer L, Trunečka P, Gridelli B, Roy A, Vitale A, Valdivieso A, Varo E, Seehofer D, Lynch S, Samuel D, Ericzon BG, Boudjema K, Karpf C, Undre N (2011) Pharmacokinetics for once- versus twice-daily Tacrolimus formulations in de novo liver transplantation: a randomized, open-label trial. Liver Transpl 17:167-177