Efficacy of intravenous lidocaine to reduce pain and distress associated with propofol infusion in pediatric patients during procedural sedation

Pediatric Emergency Care

Volumn 29, Issue 1, 2013, Pages 13-16

  Depue, Kent ^a   Christopher, Norman C ^a,b   Raed, Mona ^b   Forbes, Michael L ^c,d   Besunder, James ^c,d   Reed, Michael D ^b,c,d  

^a CHILDREN S MEDICAL CENTER   (United States)

^b Children's Hospital Medical Center of Akron (CHMCA)   (United States)

^c NORTHEAST OHIO MEDICAL UNIVERSITY   (United States)

^d Wilford Hall Medical Center   (United States)

Author keywords

lidocaine; pain; pediatric procedural sedation; propofol; visual analog scale

Indexed keywords

LIDOCAINE; PLACEBO; PROPOFOL;

ANALGESIA; ARTICLE; CHILD; CONTROLLED STUDY; DEEP SEDATION; DISTRESS SYNDROME; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PAIN; PAIN ASSESSMENT; PEDIATRIC ANESTHESIA; PRESCHOOL CHILD; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; VISUAL ANALOG SCALE;

ANALYSIS OF VARIANCE; ANESTHETICS, LOCAL; CHI-SQUARE DISTRIBUTION; CHILD; CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; INFANT; INJECTIONS, INTRAVENOUS; LIDOCAINE; MALE; PAIN MEASUREMENT; PLACEBOS; PROPOFOL; PROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84872285382     PISSN: 07495161     EISSN: 15351815     Source Type: Journal    
DOI: 10.1097/PEC.0b013e31827b227e     Document Type: Article

References (21)

1. Picard P, Tramer MR. Prevention of pain on injection with propofol: a quantitative systematic review. Anesth Analg. 2000;90:963-969.
2. Valtonen M, Iisalo E, Kanto J, et al. Propofol as an induction agent in children: pain on injection and pharmacokinetics. Acta Anaesthesiol Scand. 1989;33:152-155.
3. Cameron E, Johnstone G, Crofts S, et al. The minimum effective dose of lignocaine to prevent injection pain due to propofol in children. Anaesthesia. 1992;47:604-606.
4. Nyman Y, von Hofsten K, Georgiadi A, et al. Propofol injection pain in children: a prospective randomized double-blind trial of a new propofol formulation versus propofol with added lidocaine. Br J Anaesth. 2005;95:222-225.
5. Ganta R, Fee JP. Pain on injection of propofol: comparison of lignocaine with metoclopramide. Br J Anaesth. 1992;69:316-317.
6. Magnar D, Holak EJ. Tourniquet at 50 mmHg followed by intravenous lidocaine diminishes hand pain associated with propofol injection. Anesth Analg. 1992;74:250-252.
7. Madenoglu H, Yildiz K, Dogru K, et al. Efficacy of different doses of lidocaine in the prevention of pain due to propofol injection: a randomized, open-label trial in 120 patients. Curr Ther Res. 2003;64:310-316.
8. Rahman Al-Refai A, Al-Mujadi H, Petrova Ivanova M, et al. Prevention of pain on injection of propofol: a comparison of remifentanil with alfentanil in children. Minerva Anesth. 2007;73:219-223.
9. Apiliogullari S, Keles B, Apiliogullari B, et al. Comparison of diphenhydramine and lidocaine for prevention of pain after injection of propofol: a double-blind, placebo-controlled, randomized study. Euro J Anaesth. 2007;24:235-238.
10. Helbo-Hansen S, Westergaard V, Krogh BL, et al. The reduction of pain on injection of propofol: the effect of addition of lignocaine. Acta Anaesth Scand. 1988;32: 502-504.
11. McClusky A, Currer BA, Sayeed I. The efficacy of 5% lidocaine-prilocaine (EMLA) cream on pain during intravenous injection of propofol. Anesth Analg. 2003;97:713-714.
12. Yokota S, Komatsu T, Komura Y, et al. Pretreatment with topical 60% lidocaine tape reduces pain on injection of propofol. Anesth Analg. 1997;85:672-674.
13. Huang CL, Wang YP, Cheng YJ, et al. The effect of carrier intravenous fluid speed on the injection pain of propofol. Anaesth Analg. 1995;81:1087-1088.
14. McCrirrick A, Hunter S. Pain on injection of propofol: the effect of injectate temperature. Anaesthesia. 1990;45:443-444.
15. Gajraj NM, Nathanson MH. Preventing pain during injection of propofol: the optimal dose of lidocaine. J Clin Anesth. 1996;8:575-577.
16. Manworren RCB, Hynan LS. Clinical validation of FLACC: preverbal patient pain scale. Pediatr Nurs. 2003;29:140-146.
17. de Jong AEE, Bremer M, Schouten M, et al. Reliability and validity of the pain observation scale for young children and the visual analogue scale in children with burns. Burns. 2005;31:198-204.
18. Maki DG, Ringer M. Risk factors for infusion-related phlebitis with small peripheral venous catheters. A randomized controlled trial. Ann Intern Med. 1991;114:845-854.
19. dos Reis PE, Silveira RC, Vasques CI, et al. Pharmacological interventions to treat phlebitis: systematic review [review]. J Infus Nurs. 2009;32:74-79.
20. Ho CM, Tsou MY, Sun MS, et al. The optimal effective concentration of lidocaine to reduce pain on injection of propofol. J Clin Anesth. 1999;11:296-300.
21. Nishiyama T. How to decrease pain at rapid injection of propofol: effectiveness of flurbiprofen. J Anesth. 2005;19:273-276.