-
2
-
-
0035109764
-
Chronic pancreatitis: Diagnosis, classification, and new genetic developments
-
Etemad B, Whitcomb DC. Chronic pancreatitis: diagnosis, classification, and new genetic developments. Gastroenterology. 2001;120:682-707.
-
(2001)
Gastroenterology
, vol.120
, pp. 682-707
-
-
Etemad, B.1
Whitcomb, D.C.2
-
3
-
-
10144246566
-
Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene
-
Whitcomb DC, Gorry MC, Preston RA, Furey W, Sossenheimer MJ, Ulrich CD, et al. Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat Genet. 1996;14:141-5.
-
(1996)
Nat Genet
, vol.14
, pp. 141-145
-
-
Whitcomb, D.C.1
Gorry, M.C.2
Preston, R.A.3
Furey, W.4
Sossenheimer, M.J.5
Ulrich, C.D.6
-
4
-
-
44149094982
-
Hereditary pancreatitis caused by a double gain-of-function trypsinogen mutation
-
Masson E, Le Maréchal C, Delcenserie R, Chen JM, Férec C. Hereditary pancreatitis caused by a double gain-of-function trypsinogen mutation. Hum Genet. 2008;123:521-9.
-
(2008)
Hum Genet
, vol.123
, pp. 521-529
-
-
Masson, E.1
Le Maréchal, C.2
Delcenserie, R.3
Chen, J.M.4
Férec, C.5
-
5
-
-
0034039578
-
Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis
-
Witt H, Luck W, Hennies HC, Classen M, Kage A, Lass U, et al. Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis. Nat Genet. 2000;25:213-6.
-
(2000)
Nat Genet
, vol.25
, pp. 213-216
-
-
Witt, H.1
Luck, W.2
Hennies, H.C.3
Classen, M.4
Kage, A.5
Lass, U.6
-
6
-
-
0033857452
-
SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis
-
Pfützer RH, Barmada MM, Brunskill AP, Finch R, Hart PS, Neoptolemos J, et al. SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis. Gastroenterology. 2000;119:615-23.
-
(2000)
Gastroenterology
, vol.119
, pp. 615-623
-
-
Pfützer, R.H.1
Barmada, M.M.2
Brunskill, A.P.3
Finch, R.4
Hart, P.S.5
Neoptolemos, J.6
-
7
-
-
0035124067
-
Mutations of the pancreatic secretory trypsin inhibitor (PSTI) gene in idiopathic chronic pancreatitis
-
Chen JM, Mercier B, Audrezet MP, Raguenes O, Quere I, Ferec C. Mutations of the pancreatic secretory trypsin inhibitor (PSTI) gene in idiopathic chronic pancreatitis. Gastroenterology. 2001;120:1061-4.
-
(2001)
Gastroenterology
, vol.120
, pp. 1061-1064
-
-
Chen, J.M.1
Mercier, B.2
Audrezet, M.P.3
Raguenes, O.4
Quere, I.5
Ferec, C.6
-
8
-
-
23844540043
-
Mutations in the serine protease inhibitor Kazal type 1 (SPINK1) gene in Japanese patients with pancreatitis
-
Kume K, Masamune A, Mizutamari H, Kaneko K, Kikuta K, Satoh M, et al. Mutations in the serine protease inhibitor Kazal type 1 (SPINK1) gene in Japanese patients with pancreatitis. Pancreatology. 2005;5:354-60.
-
(2005)
Pancreatology
, vol.5
, pp. 354-360
-
-
Kume, K.1
Masamune, A.2
Mizutamari, H.3
Kaneko, K.4
Kikuta, K.5
Satoh, M.6
-
9
-
-
44849092282
-
Pathways to injury in chronic pancreatitis: Decoding the role of the high-risk SPINK1 N34S haplotype using meta-analysis
-
Aoun E, Chang CC, Greer JB, Papachristou GI, Barmada MM, Whitcomb DC. Pathways to injury in chronic pancreatitis: decoding the role of the high-risk SPINK1 N34S haplotype using meta-analysis. PLoS ONE. 2008;3:e2003.
-
(2008)
PLoS ONE
, vol.3
-
-
Aoun, E.1
Chang, C.C.2
Greer, J.B.3
Papachristou, G.I.4
Barmada, M.M.5
Whitcomb, D.C.6
-
10
-
-
37549072225
-
Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis
-
Rosendahl J, Witt H, Szmola R, Bhatia E, Ozsvári B, Landt O, et al. Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis. Nat Genet. 2008;40:78-82.
-
(2008)
Nat Genet
, vol.40
, pp. 78-82
-
-
Rosendahl, J.1
Witt, H.2
Szmola, R.3
Bhatia, E.4
Ozsvári, B.5
Landt, O.6
-
11
-
-
0022651240
-
Activation of pancreatic zymogens. Normal activation, premature intrapancreatic activation, protective mechanisms against inappropriate activation
-
Rinderknecht H. Activation of pancreatic zymogens. Normal activation, premature intrapancreatic activation, protective mechanisms against inappropriate activation. Dig Dis Sci. 1986;31: 314-21.
-
(1986)
Dig Dis Sci
, vol.31
, pp. 314-321
-
-
Rinderknecht, H.1
-
12
-
-
0036789203
-
Tropical calcific pancreatitis: Strong association with SPINK1 trypsin inhibitor mutations
-
Bhatia E, Choudhuri G, Sikora SS, Landt O, Kage A, Becker M, et al. Tropical calcific pancreatitis: strong association with SPINK1 trypsin inhibitor mutations. Gastroenterology. 2002;123:1020-5.
-
(2002)
Gastroenterology
, vol.123
, pp. 1020-1025
-
-
Bhatia, E.1
Choudhuri, G.2
Sikora, S.S.3
Landt, O.4
Kage, A.5
Becker, M.6
-
13
-
-
63849134622
-
Minigene analysis of intronic variants in common SPINK1 haplotypes associated with chronic pancreatitis
-
Kereszturi E, Király O, Sahin-Tóth M. Minigene analysis of intronic variants in common SPINK1 haplotypes associated with chronic pancreatitis. Gut. 2009;58:545-9.
-
(2009)
Gut
, vol.58
, pp. 545-549
-
-
Kereszturi, E.1
Király, O.2
Sahin-Tóth, M.3
-
14
-
-
76349094276
-
SPINK1 N34S is strongly associated with recurrent acute pancreatitis but is not a risk factor for the first or sentinel acute pancreatitis event
-
Aoun E, Muddana V, Papachristou GI, Whitcomb DC. SPINK1 N34S is strongly associated with recurrent acute pancreatitis but is not a risk factor for the first or sentinel acute pancreatitis event. Am J Gastroenterol. 2010;105:446-51.
-
(2010)
Am J Gastroenterol
, vol.105
, pp. 446-451
-
-
Aoun, E.1
Muddana, V.2
Papachristou, G.I.3
Whitcomb, D.C.4
-
15
-
-
79955885693
-
Genetic background is different between sentinel and recurrent acute pancreatitis
-
Masamune A, Ariga H, Kume K, Kakuta Y, Satoh K, Satoh A, et al. Genetic background is different between sentinel and recurrent acute pancreatitis. J Gastroenterol Hepatol. 2011;26: 974-8.
-
(2011)
J Gastroenterol Hepatol
, vol.26
, pp. 974-978
-
-
Masamune, A.1
Ariga, H.2
Kume, K.3
Kakuta, Y.4
Satoh, K.5
Satoh, A.6
-
16
-
-
77956673888
-
Phenotypic variability of the homozygous IVS3+2T[C mutation in the serine protease inhibitor Kazal type 1 (SPINK1) gene in patients with chronic pancreatitis
-
Ota Y, Masamune A, Inui K, Kume K, Shimosegawa T, Kikuyama M. Phenotypic variability of the homozygous IVS3+2T[C mutation in the serine protease inhibitor Kazal type 1 (SPINK1) gene in patients with chronic pancreatitis. Tohoku J Exp Med. 2010;221:197-201.
-
(2010)
Tohoku J Exp Med
, vol.221
, pp. 197-201
-
-
Ota, Y.1
Masamune, A.2
Inui, K.3
Kume, K.4
Shimosegawa, T.5
Kikuyama, M.6
-
17
-
-
0018823381
-
Serum pancreatic secretory trypsin inhibitor in acute pancreatitis
-
Ogawa M, Kitahara T, Fujimoto K, Tanaka S, Takatsuka Y, Kosaki G. Serum pancreatic secretory trypsin inhibitor in acute pancreatitis. Lancet. 1980;2:205.
-
(1980)
Lancet
, vol.2
, pp. 205
-
-
Ogawa, M.1
Kitahara, T.2
Fujimoto, K.3
Tanaka, S.4
Takatsuka, Y.5
Kosaki, G.6
-
18
-
-
0023003573
-
Elevated pancreatic secretory trypsin inhibitor levels during severe inflammatory disease, renal insufficiency, and after various surgical procedures
-
Lasson A, Borgström A, Ohlsson K. Elevated pancreatic secretory trypsin inhibitor levels during severe inflammatory disease, renal insufficiency, and after various surgical procedures. Scand J Gastroenterol. 1986;21:1275-80.
-
(1986)
Scand J Gastroenterol
, vol.21
, pp. 1275-1280
-
-
Lasson, A.1
Borgström, A.2
Ohlsson, K.3
-
19
-
-
33745000756
-
Biochemistry and clinical role of trypsinogens and pancreatic secretory trypsin inhibitor
-
Paju A, Stenman UH. Biochemistry and clinical role of trypsinogens and pancreatic secretory trypsin inhibitor. Crit Rev Clin Lab Sci. 2006;43:103-42.
-
(2006)
Crit Rev Clin Lab Sci
, vol.43
, pp. 103-142
-
-
Paju, A.1
Stenman, U.H.2
-
20
-
-
0021848238
-
Appearance mechanism and molecular heterogeneity of serum pancreatic secretory trypsin inhibitor (PSTI)
-
Nakano I, Funakoshi A, Sumii T, Miyazaki K, Oogami Y, Kimura T, et al. Appearance mechanism and molecular heterogeneity of serum pancreatic secretory trypsin inhibitor (PSTI). Gastroenterol Jpn. 1985;20:354-60.
-
(1985)
Gastroenterol Jpn
, vol.20
, pp. 354-360
-
-
Nakano, I.1
Funakoshi, A.2
Sumii, T.3
Miyazaki, K.4
Oogami, Y.5
Kimura, T.6
-
21
-
-
0023726551
-
The measurement of serum immunoreactive pancreatic secretory trypsin inhibitor in gastrointestinal cancer and pancreatic disease
-
Satake K, Inui A, Sogabe T, Yoshii Y, Nakata B, Tanaka H, et al. The measurement of serum immunoreactive pancreatic secretory trypsin inhibitor in gastrointestinal cancer and pancreatic disease. Int J Pancreatol. 1988;3:323-31.
-
(1988)
Int J Pancreatol
, vol.3
, pp. 323-331
-
-
Satake, K.1
Inui, A.2
Sogabe, T.3
Yoshii, Y.4
Nakata, B.5
Tanaka, H.6
-
22
-
-
33746117691
-
[-215G>A; IVS3+2T>C] mutation in the SPINK1 gene causes exon 3 skipping and loss of the trypsin binding site
-
Kume K, Masamune A, Kikuta K, Shimosegawa T. [-215G>A; IVS3+2T>C] mutation in the SPINK1 gene causes exon 3 skipping and loss of the trypsin binding site. Gut. 2006;55:1214.
-
(2006)
Gut
, vol.55
, pp. 1214
-
-
Kume, K.1
Masamune, A.2
Kikuta, K.3
Shimosegawa, T.4
-
23
-
-
34948901262
-
Missense mutations in pancreatic secretory trypsin inhibitor (SPINK1) cause intracellular retention and degradation
-
Király O, Wartmann T, Sahin-Tóth M. Missense mutations in pancreatic secretory trypsin inhibitor (SPINK1) cause intracellular retention and degradation. Gut. 2007;56:1433-8.
-
(2007)
Gut
, vol.56
, pp. 1433-1438
-
-
Király, O.1
Wartmann, T.2
Sahin-Tóth, M.3
-
24
-
-
34548186235
-
Functional analysis of pancreatitis-associated missense mutations in the pancreatic secretory trypsin inhibitor (SPINK1) gene
-
Boulling A, Le Maréchal C, Trouvé P, Raguénès O, Chen JM, Férec C. Functional analysis of pancreatitis-associated missense mutations in the pancreatic secretory trypsin inhibitor (SPINK1) gene. Eur J Hum Genet. 2007;15:936-42.
-
(2007)
Eur J Hum Genet
, vol.15
, pp. 936-942
-
-
Boulling, A.1
Le Maréchal, C.2
Trouvé, P.3
Raguénès, O.4
Chen, J.M.5
Férec, C.6
-
25
-
-
84872272535
-
Normal level and normal range of serum PSTI concentration
-
Kosaki G, Ogawa M, editors. Tokyo: Igaku Tosho Shuppan; (in Japanese)
-
Ogawa M. Normal level and normal range of serum PSTI concentration. In: Kosaki G, Ogawa M, editors. Pancreatic secretory trypsin inhibitor. Tokyo: Igaku Tosho Shuppan; 1985. p. 91-3 (in Japanese).
-
(1985)
Pancreatic Secretory Trypsin Inhibitor
, pp. 91-93
-
-
Ogawa, M.1
-
26
-
-
84863260709
-
Functional analysis of eight missense mutations in the SPINK1 gene
-
Boulling A, Keiles S, Masson E, Chen JM, Férec C. Functional analysis of eight missense mutations in the SPINK1 gene. Pancreas. 2011;41:329-30.
-
(2011)
Pancreas
, vol.41
, pp. 329-330
-
-
Boulling, A.1
Keiles, S.2
Masson, E.3
Chen, J.M.4
Férec, C.5
-
27
-
-
0036857490
-
Functional analysis of recombinant pancreatic secretory trypsin inhibitor protein with amino-acid substitution
-
Kuwata K, Hirota M, Shimizu H, Nakae M, Nishihara S, Takimoto A, Mitsushima K, Kikuchi N, Endo K, Inoue M, Ogawa M. Functional analysis of recombinant pancreatic secretory trypsin inhibitor protein with amino-acid substitution. J Gastroenterol. 2002;37:928-34.
-
(2002)
J Gastroenterol
, vol.37
, pp. 928-934
-
-
Kuwata, K.1
Hirota, M.2
Shimizu, H.3
Nakae, M.4
Nishihara, S.5
Takimoto, A.6
Mitsushima, K.7
Kikuchi, N.8
Endo, K.9
Inoue, M.10
Ogawa, M.11
-
28
-
-
34248158166
-
N34S mutation in the SPINK1 gene is not associated with alternative splicing
-
Masamune A, Kume K, Takagi Y, Kikuta K, Satoh K, Satoh A, Shimosegawa T. N34S mutation in the SPINK1 gene is not associated with alternative splicing. Pancreas. 2007;34:423-8.
-
(2007)
Pancreas
, vol.34
, pp. 423-428
-
-
Masamune, A.1
Kume, K.2
Takagi, Y.3
Kikuta, K.4
Satoh, K.5
Satoh, A.6
Shimosegawa, T.7
-
29
-
-
33745559705
-
Relationship between pancreatic secretory trypsin inhibitor and early recurrence of intrahepatic cholangiocarcinoma following surgical resection
-
Tonouchi A, Ohtsuka M, Ito H, Kimura F, Shimizu H, Kato M, Nimura Y, Iwase K, Hiwasa T, Seki N, Takiguchi M, Miyazaki M. Relationship between pancreatic secretory trypsin inhibitor and early recurrence of intrahepatic cholangiocarcinoma following surgical resection. Am J Gastroenterol. 2006;101:1601-10.
-
(2006)
Am J Gastroenterol
, vol.101
, pp. 1601-1610
-
-
Tonouchi, A.1
Ohtsuka, M.2
Ito, H.3
Kimura, F.4
Shimizu, H.5
Kato, M.6
Nimura, Y.7
Iwase, K.8
Hiwasa, T.9
Seki, N.10
Takiguchi, M.11
Miyazaki, M.12
-
30
-
-
67349251220
-
High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer
-
Gaber A, Johansson M, Stenman UH, Hotakainen K, Pontén F, Glimelius B, Bjartell A, Jirström K, Birgisson H. High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer. Br J Cancer. 2009;100:1540-8.
-
(2009)
Br J Cancer
, vol.100
, pp. 1540-1548
-
-
Gaber, A.1
Johansson, M.2
Stenman, U.H.3
Hotakainen, K.4
Pontén, F.5
Glimelius, B.6
Bjartell, A.7
Jirström, K.8
Birgisson, H.9
-
31
-
-
35748961384
-
Increased expression of tumorassociated trypsin inhibitor, TATI, in prostate cancer and in androgen-independent 22Rv1 cells
-
Paju A, Hotakainen K, Cao Y, Laurila T, Gadaleanu V, Hemminki A, Stenman UH, Bjartell A. Increased expression of tumorassociated trypsin inhibitor, TATI, in prostate cancer and in androgen-independent 22Rv1 cells. Eur Urol. 2007;52:1670-9.
-
(2007)
Eur Urol
, vol.52
, pp. 1670-1679
-
-
Paju, A.1
Hotakainen, K.2
Cao, Y.3
Laurila, T.4
Gadaleanu, V.5
Hemminki, A.6
Stenman, U.H.7
Bjartell, A.8
-
32
-
-
70349479239
-
Serine protease inhibitor Kazal type 1 promotes proliferation of pancreatic cancer cells through the epidermal growth factor receptor
-
Ozaki N, Ohmuraya M, Hirota M, Ida S, Wang J, Takamori H, Higashiyama S, Baba H, Yamamura K. Serine protease inhibitor Kazal type 1 promotes proliferation of pancreatic cancer cells through the epidermal growth factor receptor. Mol Cancer Res. 2009;7:1572-81.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1572-1581
-
-
Ozaki, N.1
Ohmuraya, M.2
Hirota, M.3
Ida, S.4
Wang, J.5
Takamori, H.6
Higashiyama, S.7
Baba, H.8
Yamamura, K.9
|