Regular aerobic exercise protects against impaired fasting plasma glucose-associated vascular endothelial dysfunction with aging

Clinical Science

Volumn 124, Issue 5, 2013, Pages 325-331

  Devan, Allison E ^a   Eskurza, Iratxe ^a   Pierce, Gary L ^a   Walker, Ashley E ^a   Jablonski, Kristen L ^a   Kaplon, Rachelle E ^a   Seals, Douglas R ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Aging; Flow mediated dilation; Physical fitness; Prediabetic state

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; GLUCOSE; GLYCERYL TRINITRATE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; AEROBIC EXERCISE; AGING; ARTERY DILATATION; ARTICLE; BODY MASS; BRACHIAL ARTERY; CARBOHYDRATE INTAKE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ECHOGRAPHY; ENDOTHELIAL DYSFUNCTION; FAT INTAKE; FEMALE; FLOW MEDIATED DILATATION; GLUCOSE BLOOD LEVEL; HEART RATE; HIP CIRCUMFERENCE; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN INTAKE; SYSTOLIC BLOOD PRESSURE; VASCULAR ENDOTHELIUM; VITAMIN INTAKE; WAIST CIRCUMFERENCE; WAIST HIP RATIO;

ADOLESCENT; ADULT; AGED; AGING; BLOOD GLUCOSE; BRACHIAL ARTERY; CARDIOVASCULAR DISEASES; COHORT STUDIES; DATABASES, FACTUAL; ENDOTHELIUM, VASCULAR; EXERCISE; FASTING; FEMALE; HUMANS; INSULIN; MALE; MIDDLE AGED; PHYSICAL FITNESS; PREDIABETIC STATE; REGIONAL BLOOD FLOW; YOUNG ADULT;

EID: 84872256593     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20120291     Document Type: Article

References (41)

1. Roger, V. L., Go, A. S., Lloyd-Jones, D. M., Benjamin, E. J., Berry, J. D., Borden, W. B., Bravata, D. M., Dai, S., Ford, E. S., Fox, C. S. et al. (2012) Heart disease and stroke statistics - 2012 update: a report from the American Heart Association. Circulation 125, e2-e220
2. Shimokawa, H. (2010) Hydrogen peroxide as an endotheliumderived hyperpolarizing factor. Pflugers Arch. 459, 915-922
3. Widlansky, M. E., Gokce, N., Keaney, Jr, J. F. and Vita, J. A. (2003) The clinical implications of endothelial dysfunction. J. Am. Coll. Cardiol. 42, 1149-1160
4. Seals, D. R., Jablonski, K. L. and Donato, A. J. (2011) Aging and vascular endothelial function in humans. Clin. Sci. 120, 357-375
5. Sudano, I., Roas, S. and Noll, G. (2011) Vascular abnormalities in essential hypertension. Curr. Pharm. Des. 17, 3039-3044
6. Bauer, V. and Sotnikova, R. (2010) Nitric oxide - the endothelium-derived relaxing factor and its role in endothelial functions. Gen. Physiol. Biophys. 29, 319-340
7. Vehkavaara, S., Seppala-Lindroos, A., Westerbacka, J., Groop, P. H. and Yki-Jarvinen, H. (1999) In vivo endothelial dysfunction characterizes patients with impaired fasting glucose. Diabetes Care 22, 2055-2060
8. Xiang, G., Pu, J., Yue, L., Hou, J. and Sun, H. (2011) Alpha-lipoic acid can improve endothelial dysfunction in subjects with impaired fasting glucose. Metab., Clin. Exp. 60, 480-485
9. Xiang, G. D. and Wang, Y. L. (2004) Regular aerobic exercise training improves endothelium-dependent arterial dilation in patients with impaired fasting glucose. Diabetes Care 27, 801-802
10. Su, Y., Liu, X. M., Sun, Y. M., Jin, H. B., Fu, R., Wang, Y. Y., Wu, Y. and Luan, Y. (2008) The relationship between endothelial dysfunction and oxidative stress in diabetes and prediabetes. Int. J. Clin. Pract. 62, 877-882
11. James, C., Bullard, K. M., Rolka, D. B., Geiss, L. S., Williams, D. E., Cowie, C. C., Albright, A. and Gregg, E. W. (2011) Implications of alternative definitions of prediabetes for prevalence in U.S. adults. Diabetes Care 34, 387-391
12. Schini-Kerth, V. B., Auger, C., Etienne-Selloum, N. and Chataigneau, T. (2010) Polyphenol-induced endotheliumdependent relaxations role of NO and EDHF. Adv. Pharmacol. 60, 133-175
13. Seals, D. R., Walker, A. E., Pierce, G. L. and Lesniewski, L. A. (2009) Habitual exercise and vascular ageing. J. Physiol. 587, 5541-5549
14. Eskurza, I., Monahan, K. D., Robinson, J. A. and Seals, D. R. (2004) Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing. J. Physiol. 556, 315-324
15. Pierce, G. L., Donato, A. J., Larocca, T. J., Eskurza, I., Silver, A. E. and Seals, D. R. (2011) Habitually exercising older men do not demonstrate age-associated vascular endothelial oxidative stress. Aging Cell 10, 1032-1037
16. Seals, D. R., Desouza, C. A., Donato, A. J. and Tanaka, H. (2008) Habitual exercise and arterial aging. J. Appl. Physiol. 105, 1323-1332
17. Pierce, G. L., Eskurza, I., Walker, A. E., Fay, T. N. and Seals, D. R. (2011) Sex-specific effects of habitual aerobic exercise on brachial artery flow-mediated dilation in middle-aged and older adults. Clin. Sci. 120, 13-23
18. Schini-Kerth, V. B., Auger, C., Kim, J. H., Etienne-Selloum, N. and Chataigneau, T. (2010) Nutritional improvement of the endothelial control of vascular tone by polyphenols: role of NO and EDHF. Pflugers Arch. 459, 853-862
19. Van Pelt, R. E., Davy, K. P., Stevenson, E. T., Wilson, T. M., Jones, P. P., Desouza, C. A. and Seals, D. R. (1998) Smaller differences in total and regional adiposity with age in women who regularly perform endurance exercise. Am. J. Physiol. Endocrinol. Metab. 275, E626-634
20. Garland, C. J., Hiley, C. R. and Dora, K. A. (2011) EDHF: spreading the influence of the endothelium. Br. J. Pharmacol. 164, 839-852
21. Gates, P. E., Tanaka, H., Hiatt, W. R. and Seals, D. R. (2004) Dietary sodium restriction rapidly improves large elastic artery compliance in older adults with systolic hypertension. Hypertension 44, 35-41
22. Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F. and Turner, R. C. (1985) Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28, 412-419
23. Jin, X., Satoh-Otonashi, Y., Zamami, Y., Takatori, S., Hashikawa-Hobara, N., Kitamura, Y. and Kawasaki, H. (2011) New molecular mechanisms for cardiovascular disease: contribution of endothelium-derived hyperpolarizing factor in the regulation of vasoconstriction in peripheral resistance arteries. J. Pharmacol. Sci. 116, 332-336
24. Barton, M. (2010) Obesity and aging: determinants of endothelial cell dysfunction and atherosclerosis. Pflugers Arch. 460, 825-837
25. Jin, X., Otonashi-Satoh, Y., Zamami, Y., Koyama, T., Sun, P., Kitamura, Y. and Kawasaki, H. (2010) Endothelial modulation of agonist-induced vasoconstriction in mesenteric microcirculation. Yakugaku Zasshi 130, 723-728
26. Gates, P. E., Boucher, M. L., Silver, A. E., Monahan, K. D. and Seals, D. R. (2007) Impaired flow-mediated dilation with age is not explained by L-arginine bioavailability or endothelial asymmetric dimethylarginine protein expression. J. Appl. Physiol. 102, 63-71
27. Kaplon, R. E., Walker, A. E. and Seals, D. R. (2011) Plasma norepinephrine is an independent predictor of vascular endothelial function with aging in healthy women. J. Appl. Physiol. 111, 1416-1421
28. Vanhoutte, P. M. (2010) Regeneration of the endothelium in vascular injury. Cardiovasc. Drugs Ther. 24, 299-303
29. Walker, A. E., Eskurza, I., Pierce, G. L., Gates, P. E. and Seals, D. R. (2009) Modulation of vascular endothelial function by low-density lipoprotein cholesterol with aging: influence of habitual exercise. Am. J. Hypertens. 22, 250-256
30. Ramli, J., CalderonArtero, P., Block, R. C. and Mousa, S. A. (2011) Novel therapeutic targets for preserving a healthy endothelium: strategies for reducing the risk of vascular and cardiovascular disease. Cardiol. J. 18, 352-363
31. Zhang, D. X. and Gutterman, D. D. (2011) Transient receptor potential channel activation and endothelium-dependent dilation in the systemic circulation. J. Cardiovasc. Pharmacol. 57, 133-139
32. Okada, S., Hiuge, A., Makino, H., Nagumo, A., Takaki, H., Konishi, H., Goto, Y., Yoshimasa, Y. and Miyamoto, Y. (2010) Effect of exercise intervention on endothelial function and incidence of cardiovascular disease in patients with type 2 diabetes. J. Atheroscler. Thromb. 17, 828-833
33. Taddei, S., Virdis, A., Ghiadoni, L., Salvetti, G., Bernini, G., Magagna, A. and Salvetti, A. (2001) Age-related reduction of NO availability and oxidative stress in humans. Hypertension 38, 274-279
34. Schini-Kerth, V. B., Etienne-Selloum, N., Chataigneau, T. and Auger, C. (2011) Vascular protection by natural product-derived polyphenols: in vitro and in vivo evidence. Planta Med. 77, 1161-1167
35. Kawano, H., Motoyama, T., Hirashima, O., Hirai, N., Miyao, Y., Sakamoto, T., Kugiyama, K., Ogawa, H. and Yasue, H. (1999) Hyperglycemia rapidly suppresses flow-mediated endothelium-dependent vasodilation of brachial artery. J. Am. Coll. Cardiol. 34, 146-154
36. Dessy, C., Feron, O. and Balligand, J. L. (2010) The regulation of endothelial nitric oxide synthase by caveolin: a paradigm validated in vivo and shared by the endotheliumderived hyperpolarizing factor. Pflugers Arch. 459, 817-827
37. Taddei, S., Virdis, A., Mattei, P., Ghiadoni, L., Gennari, A., Fasolo, C. B., Sudano, I. and Salvetti, A. (1995) Aging and endothelial function in normotensive subjects and patients with essential hypertension. Circulation 91, 1981-1987
38. Celermajer, D. S., Sorensen, K. E., Bull, C., Robinson, J. and Deanfield, J. E. (1994) Endothelium-dependent dilation in the systemic arteries of asymptomatic subjects relates to coronary risk factors and their interaction. J. Am. Coll. Cardiol. 24, 1468-1474
39. Rinder, M. R., Spina, R. J. and Ehsani, A. A. (2000) Enhanced endothelium-dependent vasodilation in older endurance-trained men. J. Appl. Physiol. 88, 761-766
40. Kuhr, F., Lowry, J., Zhang, Y., Brovkovych, V. and Skidgel, R. A. (2010) Differential regulation of inducible and endothelial nitric oxide synthase by kinin B1 and B2 receptors. Neuropeptides 44, 145-154
41. Yeboah, J., Crouse, J. R., Hsu, F. C., Burke, G. L. and Herrington, D. M. (2007) Brachial flow-mediated dilation predicts incident cardiovascular events in older adults: the Cardiovascular Health Study. Circulation 115, 2390-2397