Semen Quality and Sperm Function Loss by Hypercholesterolemic Diet Was Recovered by Addition of Olive Oil to Diet in Rabbit

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Saez Lancellotti, Tania E ^a,b   Boarelli, Paola V ^a,b   Romero, Aida A ^a   Funes, Abi K ^a   Cid Barria, Macarena ^b   Cabrillana, María E ^a,b   Monclus, María A ^a,b   Simón, Layla ^a   Vicenti, Amanda E ^a   Fornés, Miguel W ^a,b  

^a INSTITUTO ARGENTINO DE NIVOLOGÍA   (Argentina)

^b Universidad del Aconcagua Argentina   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; OLIVE OIL; PHOSPHOTYROSINE;

ACROSOME REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; HYPERCHOLESTEROLEMIA; LIPID ANALYSIS; MALE; NONHUMAN; PROTEIN PHOSPHORYLATION; RABBIT; SEMEN ANALYSIS; SPERM FUNCTION LOSS; SPERM QUALITY; SPERMATOZOON CAPACITATION; SPERMATOZOON MOTILITY; UROGENITAL SYSTEM PARAMETERS;

ACROSOME REACTION; ANIMALS; CHOLESTEROL, DIETARY; DIET, HIGH-FAT; DIETARY FATS, UNSATURATED; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HYPERCHOLESTEROLEMIA; MALE; PHOSPHORYLATION; PHOSPHOTYROSINE; PLANT OILS; RABBITS; SEMEN ANALYSIS; SPERM CAPACITATION; SPERM COUNT; SPERM MOTILITY; SPERMATOZOA;

ORYCTOLAGUS CUNICULUS;

EID: 84872241055     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052386     Document Type: Article

References (64)

1. Bolumar F, Olsen J, Rebagliato M, Saez-Lloret I, Bisanti L, (2000) Body mass index and delayed conception: a European multicenter study on infertility and subfecundity. Am J Epidemiol 151: 1072-1079.
2. Rich-Edwards JW, Spiegelman D, Garland M, Hertzmark E, Hunter DJ, et al. (2002) Physical activity, body mass index, and ovulatory disorder infertility. Epidemiology 13: 184-190.
3. Pasquali R, (2006) Obesity, fat distribution and infertility. Maturitas 54: 363-371.
4. Pasquali R, Gambineri A, (2006) Metabolic effects of obesity on reproduction. Reprod Biomed Online 12: 542-551.
5. Sallmen M, Sandler DP, Hoppin JA, Blair A, Baird DD, (2006) Reduced fertility among overweight and obese men. Epidemiology 17: 520-523.
6. Hammoud AO, Gibson M, Peterson CM, Hamilton BD, Carrell DT, (2006) Obesity and male reproductive potential. J Androl 27: 619-626.
7. Nguyen RH, Wilcox AJ, Skjaerven R, Baird DD, (2007) Men's body mass index and infertility. Hum Reprod 22: 2488-2493.
8. Pasquali R, Patton L, Gambineri A, (2007) Obesity and infertility. Curr Opin Endocrinol Diabetes Obes 14: 482-487.
9. Matzuk MM, Lamb DJ, (2008) The biology of infertility: research advances and clinical challenges. Nat Med 14: 1197-1213.
10. Hammoud AO, Gibson M, Peterson CM, Meikle AW, Carrell DT, (2008) Impact of male obesity on infertility: a critical review of the current literature. Fertil Steril 90: 897-904.
11. Hammoud AO, Wilde N, Gibson M, Parks A, Carrell DT, et al. (2008) Male obesity and alteration in sperm parameters. Fertil Steril 90: 2222-2225.
12. Saez Lancellotti TE, Boarelli PV, Monclus MA, Cabrillana ME, Clementi MA, et al. (2010) Hypercholesterolemia impaired sperm functionality in rabbits. PLoS One 5 (10): e13457.
13. Iqbal R, Anand S, Ounpuu S, Islam S, Zhang S, et al. (2008) Dietary Patterns and the Risk of Acute Myocardial Infarction in 52 Countries: Results of the INTERHEART Study. Circulation 118 (19): 1929-1937.
14. Díaz-Fontdevila M, Bustos-Obregón E, Fornés M, (1992) Distribution of filipin-sterol complexes in sperm membranes from hypercholesterolaemic rabbits. Andrologia 24 (5): 279-83.
15. Diaz-Fontdevila M, Bustos-Obregón E, (1993) Cholesterol and polyunsaturated acid enriched diet: effect on kinetics of the acrosome reaction in rabbit spermatozoa. Mol Reprod Dev 35 (2): 176-80.
16. Diaz-Fontdevila M, Peña W, Bustos-Obregón E, (1998) Experimental hypercholesterolaemia in rabbits. Effect on lipid domains in homologous spermatozoa. Andrologia 30 (1): 15-22.
17. Ghanayem BI, Bai R, Kissling GE, Travlos G, Hoffler U, (2010) Diet-induced obesity in male mice is associated with reduced fertility and potentiation of acrylamide-induced reproductive toxicity. Biol Reprod 82 (1): 96-104.
18. Sallmén M, Sandler DP, Hoppin JA, Blair A, Baird DD, (2006) Reduced fertility among overweight and obese men. Epidemiology 17 (5): 520-3.
19. Volle DH, Mouzat K, Duggavathi R, Siddeek B, Déchelotte P, et al. (2007) Multiple roles of the nuclear receptors for oxysterols liver X receptor to maintain male fertility. Molecular Endocrinology 21 (5): 1014-1027.
20. Ouvrier A, Alves G, Damon-Soubeyrand C, Marceau G, Cadet R, et al. (2011) Dietary cholesterol-induced post-testicular infertility. PLOS ONE 6 (11): e26966 doi:10.1371/journal.pone.0026966.
21. Yamamoto Y, Shimamoto K, Sofikitis N, Miyagawa I, (1999) Effects of hypercholesterolaemia on Leydig and Sertoli cell secretory function and the overall sperm fertilizing capacity in the rabbit. Human Reproduction 14 (6): 1516-21.
22. Nicole O, Palmer NO, Bakos HW, Owens JA, Setchell BP, et al. (2012) Diet and exercise in an obese mouse fed a high-fat diet improve metabolic health and reverse perturbed sperm function. Am J Physiol Endocrinol Metab 302: E768-E780 doi:10.1152/ajpendo.00401.2011.
23. Yanagimachi R (1994) Mammalian fertilization. In: Knobil E, Neill JD, editors. The physiology of reproduction, 2nd edition. New York: Raven Press; pp. 189-317.
24. Cross NL, (2004) Reorganization of lipid rafts during capacitation of human sperm. Biol Reprod 71: 1367-73.
25. Gadella BM, Tsai PS, Boerke A, Brewis IA, (2008) Sperm head membrane reorganization during capacitation. Int J Dev Biol 52: 473-480.
26. Katcher HI, Hill AM, Lanford JL, Yoo JS, Kris-Etherton PM, (2009) Lifestyle approaches and dietary strategies to lower LDL-cholesterol and triglycerides and raise HDL-cholesterol. Endocrinol Metab Clin North Am 38 (1): 45-78.
27. Chrysohoou C, Panagiotakos DB, Pitsavos C, Skoumas J, Toutouza M, et al. (2010) Renal function, cardiovascular disease risk factors' prevalence and 5-year disease incidence; the role of diet, exercise, lipids and inflammation markers: the ATTICA study. QJM 103 (6): 413-22.
28. Perona JS, Cabello-Moruno R, Ruiz-Gutierrez V, (2006) The role of virgin olive oil components in the modulation of endothelial function. J Nutr Biochem 17 (7): 429-45 Review.
29. Hoefel AL, Hansen F, Rosa PD, Assis AM, Silveira SL, et al. (2011) The effects of hypercaloric diets on glucose homeostasis in the rat: influence of saturated and monounsaturated dietary lipids. Cell Biochem Funct 29 (7): 569-76 doi:10.1002/cbf.1789.
30. Institutional Committee for Use of Laboratory Animals (IACUC) website. Available: http://www.fcm.uncu.edu.ar/joomla/index.php/investigacion/cicual. Accessed 2011.
31. ImageJ 1.32j website. Available: http://rsb.info.nih.gov/ij/. Accessed 2012.
32. DeBoer KF, Krueger D, (1991) A simplified artificial vagina for use in rabbits and other species. Lab Anim Sci 41 (2): 187-8.
33. Bredderman PJ, Foote RN, Yassen AM, (1964) An improved artificial vagina for collecting rabbit semen. Journal of Reproduction and Fertility 7: 401-403.
34. Institute of Laboratory Animal Resources (1996) Guide for the Care and Use of Laboratory Animals. Washington, DC: National Academic Press.
35. Burgos MH, Di Paola G, (1951) Nuevo test con eosina para apreciar la vitalidad del espermatozoide. Rev de la Soc.Arg.de Biología pp. 281-5.
36. Orgebin-Crist MC, (1969) Studies on the function of the Epididymis. Biology of Reproduction 1: 155-175.
37. Biggers JD, Whitten WK, Whittingham DG, Daniel JD (1971) Methods in Mammalian Embriology. San Francisco: Freeman. pp. 86-116.
38. Visconti PE, Galantino-Homer H, Ning X, Moore GD, Valenzuela JP, et al. (1999) Cholesterol efflux-mediated signal transduction in mammalian sperm. Betacyclodextrins initiate transmembrane signaling leading to an increase in protein tyrosine phosphorylation and capacitation. J Biol Chem 274: 3235-3242.
39. Osheroff JE, Visconti PE, Valenzuela JP, Travis AJ, Alvarez J, et al. (1999) Regulation of human sperm capacitation by a cholesterol efflux-stimulated signal transduction pathway leading to protein kinase A-mediated up-regulation of protein tyrosine phosphorylation. Molecular Human Reproduction 5 (11): 1017-1026.
40. Jeyendran RS, Van der Ven HH, Perez-Pelaez M, Crabo BG, Zaneveld LJ, (1984) Development of an assay to assess the functional integrity of the human sperm membrane and its relationship to other semen characteristics. J Reprod Fertil 70 (1): 219-28.
41. Laemmli UK, (1970) Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature 22: 680-685.
42. Pietrobon EO, Domi{dotless}nguez LA, Vincenti AE, Burgos MH, Fornes MW, (2001) Detection of mouse acrosomal reaction by acid phosphatase. Comparison with chlortetracycline and electron microscopy methods. J of Androl 22: 96-103.
43. Talbot P, Chacón RS, (1981) A Triple-Stain technique for evaluating normal acrosome reactions of human sperm. Journal of Experimental Zoology 215: 201-208.
44. GraphPad website. Available: http://www.graphpad.com/scientific-software/prism/. Accessed 2012.
45. Gupta RS, Dixit VP, (1988) Effect of dietary cholesterol on spermatogenesis. Z Ernahrungswiss 27 (4): 236-43.
46. Bataineh HN, Nusier MK, (2005) Effect of cholesterol diet on reproductive function in male albino rats. Saudi Med J 26 (3): 398-404.
47. Grizard G, Sion B, Jouanel P, Benoit P, Boucher D, (1995) Cholesterol, phospholipids and markers of the function of the accessory sex glands in the semen of men with hypercholesterolaemia. Int J Androl 18 (3): 151-6.
48. Buffone MG, Verstraeten SV, Calamera JC, Doncell GF, (2009) High Cholesterol Content and Decreased Membrane Fluidity in Human Spermatozoa Are Associated With Protein Tyrosine Phosphorylation and Functional Deficiencies. Journal of Andrology 30 (5): 552-558.
49. Violante B, Gerbaudo L, Borretta G, Tassone F, (2009) Effects of extra virgin olive oil supplementation at two different low doses on lipid profile in mild hypercholesterolemic subjects: a randomised clinical trial. J Endocrinol Invest 32 (10): 794-6.
50. Xiangdong L, Yuanwu L, Hua Z, Liming R, Qiuyan L, et al. (2011) Animal models for the atherosclerosis research: a review. Protein Cell 2 (3): 189-201.
51. Pérez-López FR, Chedraui P, Haya J, Cuadros JL, (2009) Effects of the Mediterranean diet on longevity and age-related morbid conditions. Maturitas 64 (2): 67-79.
52. Yeagle PL, (1991) Modulation of membrane function by cholesterol. Biochimie 73 (10): 1303-10.
53. Selvaraj V, Buttke DE, Asano A, Wolf CA, Nelson JL, et al. (2007) GM1 dynamics as a marker for membrane changes associated with the process of capacitation in murine and bovine spermatozoa. J Androl 28 (4): 588-99.
54. Davis BK, Niwa K, (1974) Inhibition of mammalian fertilization in vitro by membrane vesicles from seminal plasma. Proc Soc Exp Biol Med 146 (1): 11-16.
55. Saez F, Ouvrier A, Drevet J, (2011) Epididymis cholesterol homeostasis and sperm fertilizing ability. Asian Journal of Andrology 13: 11-17.
56. Visconti PE, Ning X, Fornes MW, Alvarez JG, Stein P, et al. (1999) Cholesterol efflux-mediated signal transduction in mammalian sperm: cholesterol release signals an increase in protein tyrosine phosphorylation during mouse sperm capacitation. Dev Biol 214 (2): 429-43.
57. Visconti PE, Florman HM, (2010) Mechanisms of sperm-egg interactions: between sugars and broken bonds. Sci Signal 3 (142): pe35.
58. Belmonte SA, Lopez CI, Roggero M, De Blas GA, Tomes CN, et al. (2005) Cholesterol content regulates acrosomal exocytosis by enhancing Rab3A plasma membrane association. Developmental Biology 285: 393-408.
59. Piomboni P, Gambera L, Serafini F, Campanella G, Morgante G, et al. (2008) Sperm quality improvement after natural anti-oxidant treatment of asthenoteratospermic men with leukocytospermia. Asian J Androl 10 (2): 201-6.
60. Comhaire FH, El Garem Y, Mahmoud A, Eertmans F, Schoonjans F, (2005) Combined conventional/antioxidant "Astaxanthin" treatment for male infertility: a double blind, randomized trial. Asian J Androl 7 (3): 257-62.
61. Kamal R, Gupta RS, Lohiya NK, (2003) Plants for male fertility regulation. Phytother Res 17 (6): 579-90.
62. Fatma BA, Nozha CF, Ines D, Hamadi A, Basma H, et al. (2009) Sperm quality improvement after date seed oil in vitro supplementation in spontaneous and induced oxidative stress. Asian J Androl 11 (3): 393-8.
63. Singh RB, Dubnov G, Niaz MA, Ghosh S, Singh R, et al. (2002) Effect of an Indo-Mediterranean diet on progression of coronary artery disease in high risk patients (Indo-Mediterranean Diet Heart Study): a randomised single-blind trial. Lancet 360 (9344): 1455-61.
64. Halliwell B, (1993) The role of oxygen radicals in human disease, with particular reference to the vascular system. Haemostasis (Suppl 1) pp. 118-26.