Cognitive function in small vessel disease: The additional value of diffusion tensor imaging to conventional magnetic resonance imaging: The RUN DMC study

Journal of Alzheimer's Disease

Volumn 32, Issue 3, 2012, Pages 667-676

  Van Norden, Anouk G W ^a   De Laat, Karlijn F ^a   Van Dijk, Ewoud J ^a   De Leeuw, Frank Erik ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Aging; cerebral small vessel disease; cognition; diffusion tensor imaging; imaging; lacunar infarcts; magnetic resonance imaging; microbleeds; white matter lesions

Indexed keywords

ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT;

ADULT; AGED; ANTIHYPERTENSIVE THERAPY; ARTICLE; BRAIN HEMORRHAGE; BRAIN INFARCTION; BRAIN SIZE; CEREBROVASCULAR DISEASE; COGNITION; CONTROLLED STUDY; DIABETES MELLITUS; DIAGNOSTIC TEST ACCURACY STUDY; DIFFUSION COEFFICIENT; DIFFUSION TENSOR IMAGING; EDUCATIONAL STATUS; FEMALE; FRACTIONAL ANISOTROPY; GRAY MATTER; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; LACUNAR STROKE; MAJOR CLINICAL STUDY; MALE; MEAN DIFFUSIVITY; NEUROIMAGING; NORMAL APPEARING WHITE MATTER; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RISK FACTOR; WHITE MATTER; WHITE MATTER LESION;

EID: 84872232875     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2012-120784     Document Type: Article

References (32)

1. de Groot JC, de Leeuw FE, Oudkerk M, van Gijn J, Hofman A, Jolles J, Breteler MM (2000) Cerebral white matter lesions and cognitive function: The Rotterdam Scan Study. Ann Neurol 47, 145-151. (Pubitemid 30078560)
2. Vermeer SE, Prins ND, den Heijer T, Hofman A, Koudstaal PJ, Breteler MM (2003) Silent brain infarcts and the risk of dementia and cognitive decline. N Engl J Med 348, 1215-1222. (Pubitemid 36359297)
3. van Norden AG, van den Berg HA, de Laat KF, Gons RA, van Dijk EJ, de Leeuw FE (2011) Frontal and temporal microbleeds are related to cognitive function. Stroke 42, 3382-3386.
4. de Leeuw FE, de Groot JC, Achten E, Oudkerk M, Ramos LM, Heijboer R, Hofman A, Jolles J, van Gijn J, Breteler MM (2001) Prevalence of cerebral white matter lesions in elderly people:Apopulation based magnetic resonance imaging study The Rotterdam Scan Study. J Neurol Neurosurg Psychiatry 70, 9-14. (Pubitemid 32096113)
5. VernooijMW, IkramMA,Tanghe HL,Vincent AJ, Hofman A, Krestin GP, Niessen WJ, Breteler MM, van der Lugt A (2007) Incidental findings on brain MRI in the general population. N Engl J Med 357, 1821-1828. (Pubitemid 350044802)
6. Cordonnier C, Al-Shahi Salman R, Wardlaw J (2007) Spontaneous brain microbleeds: Systematic review, subgroup analyses and standards for study design and reporting. Brain 130, 1988-2003. (Pubitemid 47236609)
7. Awad IA, Johnson PC, Spetzler RF, Hodak JA (1986) Incidental subcortical lesions identified on magnetic resonance imaging in the elderly. II. Postmortem pathological correlations. Stroke 17, 1090-1097. (Pubitemid 17008935)
8. Ikram MA, Vrooman HA, Vernooij MW, den Heijer T, Hofman A, Niessen WJ, van der Lugt A, Koudstaal PJ, Breteler MM (2008) Brain tissue volumes in the general elderly population The Rotterdam Scan Study. Neurobiol Aging 29, 882-890. (Pubitemid 351601893)
9. Jones DK, Lythgoe D, Horsfield MA, Simmons A, Williams SC, Markus HS (1999) Characterization of white matter damage in ischemic leukoaraiosis with diffusion tensor MRI. Stroke 30, 393-397. (Pubitemid 29071807)
10. Pierpaoli C, Jezzard P, Basser PJ, Barnett A, Di ChiroG(1996) Diffusion tensor MR imaging of the human brain. Radiology 201, 637-648.
11. Basser PJ, Mattiello J, LeBihan D (1994)MRdiffusion tensor spectroscopy and imaging. Biophys J 66, 259-267.
12. Basser PJ, Pierpaoli C (1996) Microstructural and physiological features of tissues elucidated by quantitative-Diffusiontensor MRI. J Magn Reson B 111, 209-219. (Pubitemid 126758682)
13. Le Bihan D, Mangin JF, Poupon C, Clark CA, Pappata S, Molko N, Chabriat H (2001) Diffusion tensor imaging: Concepts and applications. J Magn Reson Imaging 13, 534-546. (Pubitemid 32231507)
14. van NordenAG, de Laat KF, Gons RA, van Uden IW, van Dijk EJ, van Oudheusden LJ, Esselink RA, Bloem BR, van Engelen BG, Zwarts MJ, Tendolkar I, Olde-Rikkert MG, van der Vlugt MJ, ZwiersMP, Norris DG, de Leeuw FE (2011) Causes and consequences of cerebral small vessel disease The RUN DMC study: A prospective cohort study. Study rationale and protocol. BMC Neurol 11, 29.
15. Erkinjuntti T (2002) Subcortical vascular dementia. Cerebrovasc Dis 13(Suppl 2), 58-60. (Pubitemid 34233911)
16. American Psychiatric Association (2000) Diagnostic and Statistical Manual of Mental Disorders, 4th ed.Washington, D.C.
17. Ashburner J, Friston KJ (2005) Unified segmentation. Neuroimage 26, 839-851. (Pubitemid 40825026)
18. Basser PJ, Jones DK (2002) Diffusion-Tensor MRI: Theory, experimental design and data analysis - A technical review. NMR Biomed 15, 456-467. (Pubitemid 36054509)
19. Hochstenbach J, Mulder T, van Limbeek J, Donders R, SchoonderwaldtH(1998) Cognitive decline following stroke: A comprehensive study of cognitive decline following stroke. J Clin Exp Neuropsychol 20, 503-517. (Pubitemid 29030414)
20. Rosendorff C, Black HR, Cannon CP, Gersh BJ, Gore J, Izzo JL, Kaplan NM, O'Connor CM, O'Gara PT, Oparil S (2007) Treatment of hypertension in the prevention and management of ischemic heart disease: A scientific statement from the American Heart Association Council for High Blood Pressure Research and the Councils on Clinical Cardiology and Epidemiology and Prevention. Circulation 115, 2761-2788. (Pubitemid 46842793)
21. de Groot JC, de Leeuw FE, Oudkerk M, Hofman A, Jolles J, BretelerMM(2000) Cerebral white matter lesions and depressive symptoms in elderly adults. Arch Gen Psychiatry 57, 1071-1076.
22. de Leeuw FE, Korf E, Barkhof F, Scheltens P (2006) White matter lesions are associated with progression of medial temporal lobe atrophy in alzheimer disease. Stroke 37, 2248-2252. (Pubitemid 44337164)
23. Patel B, Markus HS (2011) Magnetic resonance imaging in cerebral small vessel disease and its use as a surrogate disease marker. Int J Stroke 6, 47-59.
24. Yamauchi H, Fukuyama H, Ogawa M, Ouchi Y, Kimura J (1994) Callosal atrophy in patients with lacunar infarction and extensive leukoaraiosis. An indicator of cognitive impairment. Stroke 25, 1788-1793.
25. Mungas D, Jagust WJ, Reed BR, Kramer JH, Weiner MW, Schuff N, Norman D, Mack WJ, Willis L, Chui HC (2001) MRI predictors of cognition in subcortical ischemic vascular disease and alzheimer's disease. Neurology 26, 2229-2235. (Pubitemid 34016456)
26. Nitkunan A, Barrick TR, Charlton RA, Clark CA, Markus HS (2008) Multimodal MRI in cerebral small vessel disease: Its relationship with cognition and sensitivity to change over time. Stroke 39, 1999-2005.
27. Schavione F, Charlton RA, Barrick TR, Morris RG, Markus HS (2009) Imaging age-Related cognitive decline: A comparison of diffusion tensor and magnetization transfer MRI. J Magn Reson Imaging 29, 23-30.
28. Viswanathan A, Godin O, Jouvent E, O'Sullivan M, Gschwendtner A, Peters N, Duering M, Guichard JP, Holtmannspotter M, Dufouil C, Pachai C, Bousser MG, Dichgans M, Chabriat H (2010) Impact of MRI markers in subcortical vascular dementia: A multi-modal analysis in CADASIL. Neurobiol Aging 31, 1629-1636.
29. Taylor WD, Bae JN, MacFall JR, Payne ME, Provenzale JM, Steffens DC, Krishnan KR (2007)Widespread effects of hyperintense lesions on cerebral white matter structure. Am J Roentgenol 188, 1695-1704. (Pubitemid 46866878)
30. Schmidt R, Scheltens P, Erkinjuntti T, Pantoni L, Markus HS, Wallin A, Barkhof F, Fazekas F (2004) White matter lesion progression: A surrogate endpoint for trials in cerebral smallvessel disease. Neurology 63, 139-144. (Pubitemid 38943791)
31. Holtmannspotter M, Peters N, Opherk C, Martin D, Herzog J, Bruckmann H, Samann P, Gschwendtner A, Dichgans M (2005) Diffusion magnetic resonance histograms as a surrogate marker and predictor of disease progression in CADASIL:Atwo year followup study. Stroke 36, 2559-2565.
32. Charlton RA, Schiavone F, Barrick TR, Morris RG, Markus HS (2010) Diffusion tensor imaging detects age related white matter change over a 2 year follow-up which is associated with working memory decline. J Neurol Neurosurg Psychiatry 81, 13-19.