A xenon recirculating ventilator for the newborn piglet: Developing clinical applications of xenon for neonates

European Journal of Anaesthesiology

Volumn 29, Issue 12, 2012, Pages 577-585

  Faulkner, Stuart D ^a   Downie, Neil A ^b   Mercer, Christopher J ^b   Kerr, Stuart A ^b   Sanders, Robert D ^c   Robertson, Nicola J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b AIR PRODUCTS AND CHEMICALS INC   (United States)

^c CHELSEA AND WESTMINSTER HOSPITAL   (United Kingdom)

Author keywords

Anaesthesia; Closed circuit ventilation; Neonate; Neuroprotection; Xenon

Indexed keywords

ISOFLURANE; OXYGEN; XENON;

AIR; ARTERIAL OXYGEN SATURATION; ARTICLE; BRAIN ISCHEMIA; CARBON DIOXIDE TENSION; HEART RATE; HYPOXIA; INDUCED HYPOTHERMIA; MALE; MECHANICAL VENTILATOR; NEUROPROTECTION; NEWBORN; NONHUMAN; OBSERVATIONAL STUDY; PIGLET; PROSPECTIVE STUDY;

AIR; ANESTHESIOLOGY; ANIMALS; ANIMALS, NEWBORN; AUTOMATION; CALIBRATION; HYPOXIA-ISCHEMIA, BRAIN; ISOFLURANE; MALE; OXYGEN; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; RESPIRATION, ARTIFICIAL; SWINE; TIME FACTORS; TREATMENT OUTCOME; XENON;

EID: 84872229675     PISSN: 02650215     EISSN: 13652346     Source Type: Journal    
DOI: 10.1097/EJA.0b013e3283583c4b     Document Type: Article

References (34)

1. Goto T, Suwa K, Uezono S, et al. The blood-gas partition coefficient of xenon may be lower than generally accepted. Br J Anaesth 1998; 80:255- 256.
2. Ma M, Zhang C, Liu Y, et al. The influence of hypoxia inducible factor-1alpha expression on apoptosis and proliferation of T lymphocyte in the Peyer's patches after burn with delayed fluid resuscitation in rats at high altitude. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2009; 21:296-299.
3. Ma D, Lim T, Xu J, et al. Xenon preconditioning protects against renal ischemic-reperfusion injury via HIF-1alpha activation. J Am Soc Nephrol 2009; 20:713-720.
4. Dingley J, Tooley J, Porter H, Thoresen M. Xenon provides short-term neuroprotection in neonatal rats when administered after hypoxia-ischemia. Stroke 2006; 37:501-506.
5. Homi HM, Yokoo N, Ma D, et al. The neuroprotective effect of xenon administration during transient middle cerebral artery occlusion in mice. Anesthesiology 2003; 99:876-881.
6. Ma D, Hossain M, Chow A, et al. Xenon and hypothermia combine to provide neuroprotection from neonatal asphyxia. Ann Neurol 2005; 58:182-193.
7. Ma D, Hossain M, Rajakumaraswamy N, et al. Combination of xenon and isoflurane produces a synergistic protective effect against oxygen-glucose deprivation injury in a neuronal-glial co-culture model. Anesthesiology 2003; 99:748-751.
8. Wilhelm S,Ma D,Maze M, Franks NP. Effects of xenon on in vitro and in vivo models of neuronal injury. Anesthesiology 2002; 96:1485-1491.
9. Sanders RD, Davidson A. Anesthetic-induced neurotoxicity of the neonate: time for clinical guidelines? Paediatr Anaesth 2009; 19:1141- 1146.
10. Sanders RD, Ma D, Brooks P, Maze M. Balancing paediatric anaesthesia: preclinical insights into analgesia, hypnosis, neuroprotection, and neurotoxicity. Br J Anaesth 2008; 101:597-609.
11. Ma D, Williamson P, Januszewski A, et al. Xenon mitigates isofluraneinduced neuronal apoptosis in the developing rodent brain. Anesthesiology 2007; 106:746-753.
12. Hobbs C, Thoresen M, Tucker A, et al. Xenon and hypothermia combine additively, offering long-term functional and histopathologic neuroprotection after neonatal hypoxia/ischemia. Stroke 2008; 39:1307- 1313.
13. Jayasinghe D, Gill AB, Levene MI. CBF reactivity in hypotensive and normotensive preterm infants. Pediatr Res 2003; 54:848-853.
14. Lockwood GG, Franks NP, Downie NA, et al. Feasibility and safety of delivering xenon to patients undergoing coronary artery bypass graft surgery while on cardiopulmonary bypass: phase I study. Anesthesiology 2006; 104:458-465.
15. Kunitz O, Baumert JH, Hecker K, et al. Xenon does not modify mivacurium induced neuromuscular block. Can J Anaesth 2005; 52:940-943.
16. Coburn M, Kunitz O, Baumert JH, et al. Randomized controlled trial of the haemodynamic and recovery effects of xenon or propofol anaesthesia. Br J Anaesth 2005; 94:198-202.
17. Rossaint R, Reyle-Hahn M, Schulte Am Esch J, et al. Multicenter randomized comparison of the efficacy and safety of xenon and isoflurane in patients undergoing elective surgery. Anesthesiology 2003; 98:6-13.
18. Rawat S, Dingley J. Closed-circuit xenon delivery using a standard anesthesia workstation. Anesth Analg 2010; 110:101-109.
19. Luttropp HH, Thomasson R, Dahm S, et al. Clinical experience with minimal flow xenon anesthesia. Acta Anaesthesiol Scand 1994; 38:121-125.
20. Nathan N, Sperandio M, Erdmann W, et al. PhysioFlex: a target-controlled self-regulating closed-circuit inhalation anesthesia regulator. Ann Fr Anesth Reanim 1997; 16:534-540.
21. Chakkarapani E, Thoresen M, Hobbs CE, et al. A closed-circuit neonatal xenon delivery system: a technical and practical neuroprotection feasibility study in newborn pigs. Anesth Analg 2009; 109:451-460.
22. Roehl AB, Goetzenich A, Rossaint R, et al. A practical rule for optimal flows for xenon anaesthesia in a semi-closed anaesthesia circuit. Eur J Anaesthesiol 2010; 27:660-665.
23. Baumert JH, Reyle-Hahn M, Hecker K, et al. Increased airway resistance during xenon anaesthesia in pigs is attributed to physical properties of the gas. Br J Anaesth 2002; 88:540-545.
24. Katz I, Caillibotte G, Martin AR, Arpentinier P. Property value estimation for inhaled therapeutic binary gas mixtures: He, Xe, N2O, and N2 with O2. Med Gas Res 2011; 1:28.
25. Baumert JH, Hein M, Gerets C, et al. The effect of xenon anesthesia on the size of experimental myocardial infarction. Anesth Analg 2007; 105:1200- 1206.
26. Faulkner S, Bainbridge A, Kato T, et al. Xenon augmented hypothermia reduces early lactate/N-acetylaspartate and cell death in perinatal asphyxia. Ann Neurol 2011; 70:133-150.
27. Stroobant N, Van Nooten G, Van Belleghem Y, Vingerhoets G. Relation between neurocognitive impairment, embolic load, and cerebrovascular reactivity following on- and off-pump coronary artery bypass grafting. Chest 2005; 127:1967-1976.
28. Westenskow DR, Johnson CC, Jordan WS, Gehmlich DK. Instrumentation for measuring continuous oxygen consumption of surgical patients. IEEE Trans Biomed Eng 1977; 24:331-337.
29. Hecker KE, Reyle-Hahn M, Baumert JH, et al. Minimum alveolar anesthetic concentration of isoflurane with different xenon concentrations in swine. Anesth Analg 2003; 96:119-124.
30. Hecker KE, Horn N, Baumert JH, et al. Minimum alveolar concentration (MAC) of xenon in intubated swine. Br J Anaesth 2004; 92:421-424.
31. Saito H, Saito M, Goto T, Morita S. Priming of anesthesia circuit with xenon for closed circuit anesthesia. Artif Organs 1997; 21:70-72.
32. Hanne P, Marx T, Musati S, et al. Xenon: uptake and costs. Int Anesthesiol Clin 2001; 39:43-61.
33. Lerman J. Gas flow in the upper airway: turbulent or laminar? Paediatr Anaesth 2009; 19:1241.
34. Weiss M, Gerber AC. Cuffed tracheal tubes in children: things have changed. Paediatr Anaesth 2006; 16:1005-1007.