Neddylation pathway regulates T-cell function by targeting an adaptor protein Shc and a protein kinase Erk signaling

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 2, 2013, Pages 624-629

  Jin, Hyung Seung ^a   Liao, Lujian ^b   Park, Yoon ^a   Liu, Yun Cai ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Allergy; Posttranslational modification; Signal transduction

Indexed keywords

[4 [4 [(2,3 DIHYDRO 1H INDEN 1 YL)AMINO] 7H PYRROLO[2,3 D]PYRIMIDIN 7 YL] 2 HYDROXYCYCLOPENTYLMETHYL] SULFAMATE; ADAPTOR PROTEIN; CD28 ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; NEDD8 PROTEIN; PROTEIN SHC; T LYMPHOCYTE RECEPTOR;

ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE FUNCTION; MOUSE; NEDDYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ADOPTIVE TRANSFER; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CULLIN PROTEINS; CYCLOPENTANES; GENE KNOCKDOWN TECHNIQUES; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; OLIGONUCLEOTIDES; PYRIMIDINES; RECEPTORS, ANTIGEN, T-CELL; SHC SIGNALING ADAPTOR PROTEINS; UBIQUITINS;

MUS;

EID: 84872199770     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1213819110     Document Type: Article

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